| Definition | Nocardioides sp. JS614 chromosome, complete genome. |
|---|---|
| Accession | NC_008699 |
| Length | 4,985,871 |
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The map label for this gene is ftsI [H]
Identifier: 119717293
GI number: 119717293
Start: 3268290
End: 3270050
Strand: Reverse
Name: ftsI [H]
Synonym: Noca_3069
Alternate gene names: 119717293
Gene position: 3270050-3268290 (Counterclockwise)
Preceding gene: 119717294
Following gene: 119717292
Centisome position: 65.59
GC content: 72.74
Gene sequence:
>1761_bases TTGCGCCAGCCCCGTGCACCCCGCGGCTCCCGCCGCGGCTCTCCGCAGCTGCGGCTGCGGGTCGGCTTCGTGGTGATCGC GATGACCCTCTCGGTCTTCGGGGCGCGACTGGTCCAGCTGCAGGGCCTCGACCCGAACTCCTACGCCGCCATGGCCGCCG CCGAGGGACTGGTCGAGGTCGGCCTGCCCGCCGAGCGGGGCGACATCCTCGACCGCAACGGCAAGCCGCTGGCCGGCTCG GTCGACGGGCTGATGGTCGTCGCCGACCCGGCGATGACCGCGGAGCGGGCGCCCGAGCTGGCGCGCTTCCTCTACCGCCG GCTCGACGTCGACTACGTGACGACCCTGAACAAGCTCCGCGAGCAGGGCAGCCGCTTCGAGTACATCGCCCGTCGGGTGC CGGCCACCAAGGCCACCGAGGTGCTGGATGCCGCCGAGCGGCAGGGCTTCGAGGGACTCGACACCCGGCGCGACCCGCTG CGCGACTACCCGGCCGGTGACGTCGCGGCCAACCTGGTCGGCTTCATGGGCACCGACGAGCCCCTGGCGGGGCTGGAGCG CACCTTCGACCGCCAGCTGGCCGGCACCGACGGCTCGGCACGCTACGAGGTCGGCGGCGGCAACCGGATCCCGCTCGGCG AGAACACCGTGACCGACCCGGTCGACGGCCACGACCTGCGCACGACGCTCGACCTGGACCTGCAGTGGTACACCCAGCGC GTCCTGGGGCAGACCGTGGTCGGCGCCCGCGGCGACAGCGGCTTCGCCGTGGTCATGGACAGCCGCACCGGCGAGCTGCT GGCCGTGGCGGACTACCCCACGTTCGACGCGAACGACCCCACGTCGTCGCCGAAGGCCGACCTCGGGTCGCGGGCGATGC AGGACGTCTACGAGCCGGGCTCGGTCGAGAAGGTGCTCACGGTCAGCTCGCTGCTCGACCTCGGCCTGGTCACCCCCCGC ACCAGGATCGTCGTACCCCCTCAGCTCCAGCGGGAGGACCGCCCGATCAACGACTGGTTCTCCCACGGCACCATCCACCT GACCCTCGCGGGCGTGATCGCGAAGTCCTCCAACATCGGCACCGTCCTCGCGGCCGACAAGTTCGAGCAGGGCCAGCTCT ACGACTACCTGCGCGACTTCGGCCTGGGGCGGCGCACCGACATCGGGGTGCGCGGCGAGTCCCAGGGACTGCTCCCCGAC GGCAGCGCCTGGACCCACCAGATGCAGGACCGCATCGCGTTCGGCCAGTCGCTCTCCGTGAACGGCGTGCAGATGGCCGC CGCCGTGAACACCATCGCCAACGACGGGGTGCGCGTCGCGCCGAGCCTGGTCCAGGGCGAGGCGACCACCGACGACGGCG ACGTCGTCGGCACCGACACCACCAGCAAGCGACGGGTGATCAGCACCCGGGCGGCCCACGACACGGCGCGGATGATGGAG CGCGTCGTCGACCCGGAGGTGGGCGTCGCACCGGGCGCGGCGGTGCCCGGCTATCGGGTGGCCGGCAAGACCGGCACCGC GCAGCGGGTCGGCGCGGAGTGCGGGTGCTACGACGGCACGTTCACCGTCTCCTTCGCCGGCTTCGCTCCCGCCGACGACC CCCGGTTCACGATCTACGTCGTGGTCCAGAACCCGCGCAACGGCGGGGGCGGTGGCTCGGTCGCCGGCCCGGCGTTCGCG AAGATCATGAGCTACGCCCTCCAGCGGTACGCCGTCCCGCCGACCGGCACCAAGCCCTCCCGGCTCCCGGTCGAGTGGTA G
Upstream 100 bases:
>100_bases GCAGTCCCATCAGCAACAGCAGCAACAACAGCAACAACAGCAGCAGACCCGCCGCTGACCTCCCGCCGACCCAGCCGCCC CCCGACCTCCGGAGACCCCG
Downstream 100 bases:
>100_bases CCGGGCGCAGCGATAGCCTCGCGTGGTGAGCGACTCCAACCGGCCCGCGCAGCCGCCCCGGACGCCGCTCGCGACCGTGG CGGCCTGGGCCGGTGCCGAG
Product: peptidoglycan glycosyltransferase
Products: NA
Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]
Number of amino acids: Translated: 586; Mature: 586
Protein sequence:
>586_residues MRQPRAPRGSRRGSPQLRLRVGFVVIAMTLSVFGARLVQLQGLDPNSYAAMAAAEGLVEVGLPAERGDILDRNGKPLAGS VDGLMVVADPAMTAERAPELARFLYRRLDVDYVTTLNKLREQGSRFEYIARRVPATKATEVLDAAERQGFEGLDTRRDPL RDYPAGDVAANLVGFMGTDEPLAGLERTFDRQLAGTDGSARYEVGGGNRIPLGENTVTDPVDGHDLRTTLDLDLQWYTQR VLGQTVVGARGDSGFAVVMDSRTGELLAVADYPTFDANDPTSSPKADLGSRAMQDVYEPGSVEKVLTVSSLLDLGLVTPR TRIVVPPQLQREDRPINDWFSHGTIHLTLAGVIAKSSNIGTVLAADKFEQGQLYDYLRDFGLGRRTDIGVRGESQGLLPD GSAWTHQMQDRIAFGQSLSVNGVQMAAAVNTIANDGVRVAPSLVQGEATTDDGDVVGTDTTSKRRVISTRAAHDTARMME RVVDPEVGVAPGAAVPGYRVAGKTGTAQRVGAECGCYDGTFTVSFAGFAPADDPRFTIYVVVQNPRNGGGGGSVAGPAFA KIMSYALQRYAVPPTGTKPSRLPVEW
Sequences:
>Translated_586_residues MRQPRAPRGSRRGSPQLRLRVGFVVIAMTLSVFGARLVQLQGLDPNSYAAMAAAEGLVEVGLPAERGDILDRNGKPLAGS VDGLMVVADPAMTAERAPELARFLYRRLDVDYVTTLNKLREQGSRFEYIARRVPATKATEVLDAAERQGFEGLDTRRDPL RDYPAGDVAANLVGFMGTDEPLAGLERTFDRQLAGTDGSARYEVGGGNRIPLGENTVTDPVDGHDLRTTLDLDLQWYTQR VLGQTVVGARGDSGFAVVMDSRTGELLAVADYPTFDANDPTSSPKADLGSRAMQDVYEPGSVEKVLTVSSLLDLGLVTPR TRIVVPPQLQREDRPINDWFSHGTIHLTLAGVIAKSSNIGTVLAADKFEQGQLYDYLRDFGLGRRTDIGVRGESQGLLPD GSAWTHQMQDRIAFGQSLSVNGVQMAAAVNTIANDGVRVAPSLVQGEATTDDGDVVGTDTTSKRRVISTRAAHDTARMME RVVDPEVGVAPGAAVPGYRVAGKTGTAQRVGAECGCYDGTFTVSFAGFAPADDPRFTIYVVVQNPRNGGGGGSVAGPAFA KIMSYALQRYAVPPTGTKPSRLPVEW >Mature_586_residues MRQPRAPRGSRRGSPQLRLRVGFVVIAMTLSVFGARLVQLQGLDPNSYAAMAAAEGLVEVGLPAERGDILDRNGKPLAGS VDGLMVVADPAMTAERAPELARFLYRRLDVDYVTTLNKLREQGSRFEYIARRVPATKATEVLDAAERQGFEGLDTRRDPL RDYPAGDVAANLVGFMGTDEPLAGLERTFDRQLAGTDGSARYEVGGGNRIPLGENTVTDPVDGHDLRTTLDLDLQWYTQR VLGQTVVGARGDSGFAVVMDSRTGELLAVADYPTFDANDPTSSPKADLGSRAMQDVYEPGSVEKVLTVSSLLDLGLVTPR TRIVVPPQLQREDRPINDWFSHGTIHLTLAGVIAKSSNIGTVLAADKFEQGQLYDYLRDFGLGRRTDIGVRGESQGLLPD GSAWTHQMQDRIAFGQSLSVNGVQMAAAVNTIANDGVRVAPSLVQGEATTDDGDVVGTDTTSKRRVISTRAAHDTARMME RVVDPEVGVAPGAAVPGYRVAGKTGTAQRVGAECGCYDGTFTVSFAGFAPADDPRFTIYVVVQNPRNGGGGGSVAGPAFA KIMSYALQRYAVPPTGTKPSRLPVEW
Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=561, Percent_Identity=31.729055258467, Blast_Score=225, Evalue=6e-60, Organism=Escherichia coli, GI1786854, Length=615, Percent_Identity=24.7154471544715, Blast_Score=127, Evalue=2e-30,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 62738; Mature: 62738
Theoretical pI: Translated: 5.30; Mature: 5.30
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRQPRAPRGSRRGSPQLRLRVGFVVIAMTLSVFGARLVQLQGLDPNSYAAMAAAEGLVEV CCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHCCHHEE GLPAERGDILDRNGKPLAGSVDGLMVVADPAMTAERAPELARFLYRRLDVDYVTTLNKLR CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH EQGSRFEYIARRVPATKATEVLDAAERQGFEGLDTRRDPLRDYPAGDVAANLVGFMGTDE HCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCC PLAGLERTFDRQLAGTDGSARYEVGGGNRIPLGENTVTDPVDGHDLRTTLDLDLQWYTQR HHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHH VLGQTVVGARGDSGFAVVMDSRTGELLAVADYPTFDANDPTSSPKADLGSRAMQDVYEPG HHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCC SVEKVLTVSSLLDLGLVTPRTRIVVPPQLQREDRPINDWFSHGTIHLTLAGVIAKSSNIG CHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHCCCEEEEEEEEEHCCCCCCC TVLAADKFEQGQLYDYLRDFGLGRRTDIGVRGESQGLLPDGSAWTHQMQDRIAFGQSLSV EEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC NGVQMAAAVNTIANDGVRVAPSLVQGEATTDDGDVVGTDTTSKRRVISTRAAHDTARMME CCCHHHHHHHHHHCCCEEECHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHH RVVDPEVGVAPGAAVPGYRVAGKTGTAQRVGAECGCYDGTFTVSFAGFAPADDPRFTIYV HHCCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCCCEEEEEEECCCCCCCCCEEEEE VVQNPRNGGGGGSVAGPAFAKIMSYALQRYAVPPTGTKPSRLPVEW EEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC >Mature Secondary Structure MRQPRAPRGSRRGSPQLRLRVGFVVIAMTLSVFGARLVQLQGLDPNSYAAMAAAEGLVEV CCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHCCHHEE GLPAERGDILDRNGKPLAGSVDGLMVVADPAMTAERAPELARFLYRRLDVDYVTTLNKLR CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH EQGSRFEYIARRVPATKATEVLDAAERQGFEGLDTRRDPLRDYPAGDVAANLVGFMGTDE HCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCC PLAGLERTFDRQLAGTDGSARYEVGGGNRIPLGENTVTDPVDGHDLRTTLDLDLQWYTQR HHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHH VLGQTVVGARGDSGFAVVMDSRTGELLAVADYPTFDANDPTSSPKADLGSRAMQDVYEPG HHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCC SVEKVLTVSSLLDLGLVTPRTRIVVPPQLQREDRPINDWFSHGTIHLTLAGVIAKSSNIG CHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHCCCEEEEEEEEEHCCCCCCC TVLAADKFEQGQLYDYLRDFGLGRRTDIGVRGESQGLLPDGSAWTHQMQDRIAFGQSLSV EEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC NGVQMAAAVNTIANDGVRVAPSLVQGEATTDDGDVVGTDTTSKRRVISTRAAHDTARMME CCCHHHHHHHHHHCCCEEECHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHH RVVDPEVGVAPGAAVPGYRVAGKTGTAQRVGAECGCYDGTFTVSFAGFAPADDPRFTIYV HHCCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCCCEEEEEEECCCCCCCCCEEEEE VVQNPRNGGGGGSVAGPAFAKIMSYALQRYAVPPTGTKPSRLPVEW EEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]