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The map label for this gene is yrkH [H]

Identifier: 119717161

GI number: 119717161

Start: 3118667

End: 3120025

Strand: Reverse

Name: yrkH [H]

Synonym: Noca_2937

Alternate gene names: 119717161

Gene position: 3120025-3118667 (Counterclockwise)

Preceding gene: 119717162

Following gene: 119717154

Centisome position: 62.58

GC content: 72.48

Gene sequence:

>1359_bases
ATGGCCCAGGTGGAGGTGCTCGAGACCACCGAGCTCGGCGACCGGAGCTACGTCGTCCACGACGGCACCACGGCGGTCGT
CGTGGACCCGCAGCGCGACATCGACCGGGTGGAGGGGCTCCTCGTGGCTCGCGGTCTCGCGCTCGGCGCGGTGGCGGAGA
CCCACCTCCACAACGACTACGTGAGCGGTGGCGCCGCGCTGGCGCGTCGTGCGGGTGTCGACCACCTCGTCTGTGCCGAT
GACGACGTCGCCTTTCGCCGGCGCGCCGTTCGGAGTGGCGACGAGCTCCGGTACGGCGGCCTCACGGTGCGCGCGCTGCA
CACGCCCGGGCACACCTTCCACCACCTCAGCTACGTCGCCTTCGGCGAGGACGACGACCCGCCCGCGGTGTTCACCGGCG
GGTCCCTCCTCTACGGAAGCGTCGGCCGGACCGACCTGCTCGGCCCGGAGCATGCCGAGGAGCTGACCCGCGAGCAGTTC
CGGTCCGCTCGTCGGCTCTCCGGGGCGTTCGATGACGACGCTCGGATCTTCCCCACCCACGGCTTCGGGAGCTTCTGCTC
GGCCGGATCGACCACCGGCGCGGACCGTTCGACGATGGGGGAGGAGCGCGAGCAGAACGATGCGCTCACCGCGGCCGGCG
AGGACGGGTTCGTCGAGGAGCTGCTGGCGAACCTCACGCCCTATCCCGACTACTACACGCACATGGGCGAGCGGAACGCC
GTGGGCCCGGAGCGGCCCGACCTCGCGCCTGCGGTGCCGGTCGACCCGGAGCGGTTGCGCGCCTCGATCCGCGCCGGCGA
GTGGGTGGTCGACCTGCGCAGTCGCCGGGCGTACGCGGCCGGTCATGTCAGTGGCACCGTCGGCATCGAGCTCGAGTCGG
ACCAGTTCTCGACGTACCTCGGCTGGTTGATGCCCTGGGACACGCCCGTGACGCTCATCGGCAGCAGTTCGGACCAGGTG
GCGCGGGCCCAGCGCCAGATGGTCCGGATCGGGATCGAGCGCCCTGGGGGCGCGGCGGTCGGCCGGATCGAGGACCTGGC
CGACGGTCGGCGACCCGAGTCCTACCCCCGGGCGGAGTTCGGCGACCTGGCCGGCGCACACCACGCGACCGTGCTCGACG
TGCGCCAGGACGACGAGCGGCAGCAGTCCGCGATCCCCGGGTCGCTGCACGTGCCGATCCACCGCGTGCCGGACCGGACA
GGTGAGCTGCCCCGCGACGCGAAGCTGTGGGTGCACTGCGCGTCGGGGTTCCGGGCCTCGATTGCCGCCAGCCTGCTGGC
CCGGGACGGCCACGACGTGGTGCTGATCGACGACGAGTACACGAACGCGGTGCGGCTCGGTCTCGCCGAGCAGCGCTGA

Upstream 100 bases:

>100_bases
GCGACTGACCGAGGCGGCAGGCATTTCTGGCTGCGGTGAATCATGCACCCGTGATCGGGGCACCGGGGGATCCCGTGCCC
GTCGGCTGGAAGGTGATCCC

Downstream 100 bases:

>100_bases
CCTCGCTCAGGCCACGTCGTCACCGCAGATGCGTGCTTCCGGCCCCAGCAACCGCACCAGCAGTCCCGCGGCGTGTGCGC
GAGCACCCCGGATCTCGAAC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MAQVEVLETTELGDRSYVVHDGTTAVVVDPQRDIDRVEGLLVARGLALGAVAETHLHNDYVSGGAALARRAGVDHLVCAD
DDVAFRRRAVRSGDELRYGGLTVRALHTPGHTFHHLSYVAFGEDDDPPAVFTGGSLLYGSVGRTDLLGPEHAEELTREQF
RSARRLSGAFDDDARIFPTHGFGSFCSAGSTTGADRSTMGEEREQNDALTAAGEDGFVEELLANLTPYPDYYTHMGERNA
VGPERPDLAPAVPVDPERLRASIRAGEWVVDLRSRRAYAAGHVSGTVGIELESDQFSTYLGWLMPWDTPVTLIGSSSDQV
ARAQRQMVRIGIERPGGAAVGRIEDLADGRRPESYPRAEFGDLAGAHHATVLDVRQDDERQQSAIPGSLHVPIHRVPDRT
GELPRDAKLWVHCASGFRASIAASLLARDGHDVVLIDDEYTNAVRLGLAEQR

Sequences:

>Translated_452_residues
MAQVEVLETTELGDRSYVVHDGTTAVVVDPQRDIDRVEGLLVARGLALGAVAETHLHNDYVSGGAALARRAGVDHLVCAD
DDVAFRRRAVRSGDELRYGGLTVRALHTPGHTFHHLSYVAFGEDDDPPAVFTGGSLLYGSVGRTDLLGPEHAEELTREQF
RSARRLSGAFDDDARIFPTHGFGSFCSAGSTTGADRSTMGEEREQNDALTAAGEDGFVEELLANLTPYPDYYTHMGERNA
VGPERPDLAPAVPVDPERLRASIRAGEWVVDLRSRRAYAAGHVSGTVGIELESDQFSTYLGWLMPWDTPVTLIGSSSDQV
ARAQRQMVRIGIERPGGAAVGRIEDLADGRRPESYPRAEFGDLAGAHHATVLDVRQDDERQQSAIPGSLHVPIHRVPDRT
GELPRDAKLWVHCASGFRASIAASLLARDGHDVVLIDDEYTNAVRLGLAEQR
>Mature_451_residues
AQVEVLETTELGDRSYVVHDGTTAVVVDPQRDIDRVEGLLVARGLALGAVAETHLHNDYVSGGAALARRAGVDHLVCADD
DVAFRRRAVRSGDELRYGGLTVRALHTPGHTFHHLSYVAFGEDDDPPAVFTGGSLLYGSVGRTDLLGPEHAEELTREQFR
SARRLSGAFDDDARIFPTHGFGSFCSAGSTTGADRSTMGEEREQNDALTAAGEDGFVEELLANLTPYPDYYTHMGERNAV
GPERPDLAPAVPVDPERLRASIRAGEWVVDLRSRRAYAAGHVSGTVGIELESDQFSTYLGWLMPWDTPVTLIGSSSDQVA
RAQRQMVRIGIERPGGAAVGRIEDLADGRRPESYPRAEFGDLAGAHHATVLDVRQDDERQQSAIPGSLHVPIHRVPDRTG
ELPRDAKLWVHCASGFRASIAASLLARDGHDVVLIDDEYTNAVRLGLAEQR

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI46361987, Length=186, Percent_Identity=34.4086021505376, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI14150041, Length=185, Percent_Identity=32.972972972973, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221330176, Length=222, Percent_Identity=30.1801801801802, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 49052; Mature: 48921

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVEVLETTELGDRSYVVHDGTTAVVVDPQRDIDRVEGLLVARGLALGAVAETHLHNDY
CCCEEEEEECCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSGGAALARRAGVDHLVCADDDVAFRRRAVRSGDELRYGGLTVRALHTPGHTFHHLSYVA
HCCHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCEEECCEEEEEEECCCCCEEEEEEEE
FGEDDDPPAVFTGGSLLYGSVGRTDLLGPEHAEELTREQFRSARRLSGAFDDDARIFPTH
ECCCCCCCEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
GFGSFCSAGSTTGADRSTMGEEREQNDALTAAGEDGFVEELLANLTPYPDYYTHMGERNA
CCHHHHCCCCCCCCCHHHCCCHHHHCCCEEECCCCCHHHHHHHHCCCCCHHHHHCCCCCC
VGPERPDLAPAVPVDPERLRASIRAGEWVVDLRSRRAYAAGHVSGTVGIELESDQFSTYL
CCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEHHHCCEEEECCCCCEEEEEECCCHHHHHH
GWLMPWDTPVTLIGSSSDQVARAQRQMVRIGIERPGGAAVGRIEDLADGRRPESYPRAEF
HHEECCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCHH
GDLAGAHHATVLDVRQDDERQQSAIPGSLHVPIHRVPDRTGELPRDAKLWVHCASGFRAS
HHCCCCCCEEEEECCCCCHHHHHCCCCEEECCEEECCCCCCCCCCCCEEEEEECCCCHHH
IAASLLARDGHDVVLIDDEYTNAVRLGLAEQR
HHHHHHHCCCCEEEEEECCCCCEEEECCCCCC
>Mature Secondary Structure 
AQVEVLETTELGDRSYVVHDGTTAVVVDPQRDIDRVEGLLVARGLALGAVAETHLHNDY
CCEEEEEECCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSGGAALARRAGVDHLVCADDDVAFRRRAVRSGDELRYGGLTVRALHTPGHTFHHLSYVA
HCCHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCEEECCEEEEEEECCCCCEEEEEEEE
FGEDDDPPAVFTGGSLLYGSVGRTDLLGPEHAEELTREQFRSARRLSGAFDDDARIFPTH
ECCCCCCCEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
GFGSFCSAGSTTGADRSTMGEEREQNDALTAAGEDGFVEELLANLTPYPDYYTHMGERNA
CCHHHHCCCCCCCCCHHHCCCHHHHCCCEEECCCCCHHHHHHHHCCCCCHHHHHCCCCCC
VGPERPDLAPAVPVDPERLRASIRAGEWVVDLRSRRAYAAGHVSGTVGIELESDQFSTYL
CCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEHHHCCEEEECCCCCEEEEEECCCHHHHHH
GWLMPWDTPVTLIGSSSDQVARAQRQMVRIGIERPGGAAVGRIEDLADGRRPESYPRAEF
HHEECCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCHH
GDLAGAHHATVLDVRQDDERQQSAIPGSLHVPIHRVPDRTGELPRDAKLWVHCASGFRAS
HHCCCCCCEEEEECCCCCHHHHHCCCCEEECCEEECCCCCCCCCCCCEEEEEECCCCHHH
IAASLLARDGHDVVLIDDEYTNAVRLGLAEQR
HHHHHHHCCCCEEEEEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]