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The map label for this gene is yrkH [H]

Identifier: 119717154

GI number: 119717154

Start: 3109588

End: 3110724

Strand: Reverse

Name: yrkH [H]

Synonym: Noca_2930

Alternate gene names: 119717154

Gene position: 3110724-3109588 (Counterclockwise)

Preceding gene: 119717161

Following gene: 119717153

Centisome position: 62.39

GC content: 71.33

Gene sequence:

>1137_bases
ATGGCCGACACCATCACCCCGCTCGCGCTGTTCCACGCGATCAATGCGGGCGACGTCAGCGAGATCCTCGACGTCCGGAA
CATCGACGAGTTCGAGGCCAGCAAGGTGGAGGCGAACCGTCCCGTCGCCACTCGCAACGTCCCGGTCTACCGGGTCTTCG
AGGACCTCGAGGCGGAGGCCGGCCGCACCCGCGAGGAGGCGATCGTGATCTGCGGACAGGGCAACGGCTCGCAGCTGGTG
GCCGAGGAGTTCGAGGACCTCGGCCGGCGAGCCCGGTCCCTCGAGGGCGGCACGGACGCCTGGAACCGGCTCCTGGTGCC
GATCGAGATCACCGGCCTGCCCGGCCCGGTGCGGGTGTGGCAGTTCCTACGGCCGGCCAAGGCGTGCTTGTCCTACGTCG
TCGGCGTCCCCGGCCAGCACTGCATCGTCGTGGACCCCTCGCGCCAGCCGCAGCCCTACCTCGACCTCGCGTCCGAGCAC
GGGATGTCGGTGACCCACGTGGTGGACACCCACGTGCACGCCGACCACGTCAGCGGCGGACCCCGGCTCGCGGCCGACCT
GGGCGTGGAGTACCACCTGCCGCCCGAGGACGCGGGCGGCGTGGTCCCGTTCCCCAACCGGCCGTTGAAGGACGGCGACG
TCCTCGACCTCGGGGATGCCCAGGTCCGGGTGATGAGCATGCACCTGCCCGGCCACACCCCCGGCACGATCGCGCTGCTC
GTCAGCGACAGCGTCCTGCTCGTGGGTGACACGGTCTTCGTCCGTGGGCTCGGCCGCCCCGACCTGACCGGCCAGGCCGA
CGAGCTCGCCCGCGACCTCTTCCGCAGCGTGCACGAGCGTCTGCGCCCGCTGCCCGCGCAGACGCTGATCGCCCCGGCGC
ACTGGTCGACGGCGGAGGAGGTGAACGCCGACGGTCTGGTCGTGACGTCGCTGGCGGACGTGTTCACCGCGACCCTGCTC
AACGAGAAGGCCATGGAGAGGTTCGTCGAGGAGATCGTCACCTCGCTGCCCGCGGCCCCGGACTCCTACGACACCATCCG
GCGGATCAACGCCGGCCAGGTCGCACCGCCGGAGGACGAGGTCGACATCCTCGACGTGGGCCGCAACCAGTGCGCGGCGT
CGACGTCGCTGGTCTGA

Upstream 100 bases:

>100_bases
CTGGATACTTCGACGGCCATTGCGCGGTGTGACCCAGGACACTACATTCATGAGTGCGCATATAACAACCCTGATCGATA
CCAGATCCGTAGGAGTTGCG

Downstream 100 bases:

>100_bases
TGCGGTCCGAGCCCGGGTCGTCGTCCGGTCCGGCCGAGCACCGCCGGCTGGACGAGGTCGGGGCTGCGCCGGACTACCGC
TTCACGCTGGCCAACGAGCG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MADTITPLALFHAINAGDVSEILDVRNIDEFEASKVEANRPVATRNVPVYRVFEDLEAEAGRTREEAIVICGQGNGSQLV
AEEFEDLGRRARSLEGGTDAWNRLLVPIEITGLPGPVRVWQFLRPAKACLSYVVGVPGQHCIVVDPSRQPQPYLDLASEH
GMSVTHVVDTHVHADHVSGGPRLAADLGVEYHLPPEDAGGVVPFPNRPLKDGDVLDLGDAQVRVMSMHLPGHTPGTIALL
VSDSVLLVGDTVFVRGLGRPDLTGQADELARDLFRSVHERLRPLPAQTLIAPAHWSTAEEVNADGLVVTSLADVFTATLL
NEKAMERFVEEIVTSLPAAPDSYDTIRRINAGQVAPPEDEVDILDVGRNQCAASTSLV

Sequences:

>Translated_378_residues
MADTITPLALFHAINAGDVSEILDVRNIDEFEASKVEANRPVATRNVPVYRVFEDLEAEAGRTREEAIVICGQGNGSQLV
AEEFEDLGRRARSLEGGTDAWNRLLVPIEITGLPGPVRVWQFLRPAKACLSYVVGVPGQHCIVVDPSRQPQPYLDLASEH
GMSVTHVVDTHVHADHVSGGPRLAADLGVEYHLPPEDAGGVVPFPNRPLKDGDVLDLGDAQVRVMSMHLPGHTPGTIALL
VSDSVLLVGDTVFVRGLGRPDLTGQADELARDLFRSVHERLRPLPAQTLIAPAHWSTAEEVNADGLVVTSLADVFTATLL
NEKAMERFVEEIVTSLPAAPDSYDTIRRINAGQVAPPEDEVDILDVGRNQCAASTSLV
>Mature_377_residues
ADTITPLALFHAINAGDVSEILDVRNIDEFEASKVEANRPVATRNVPVYRVFEDLEAEAGRTREEAIVICGQGNGSQLVA
EEFEDLGRRARSLEGGTDAWNRLLVPIEITGLPGPVRVWQFLRPAKACLSYVVGVPGQHCIVVDPSRQPQPYLDLASEHG
MSVTHVVDTHVHADHVSGGPRLAADLGVEYHLPPEDAGGVVPFPNRPLKDGDVLDLGDAQVRVMSMHLPGHTPGTIALLV
SDSVLLVGDTVFVRGLGRPDLTGQADELARDLFRSVHERLRPLPAQTLIAPAHWSTAEEVNADGLVVTSLADVFTATLLN
EKAMERFVEEIVTSLPAAPDSYDTIRRINAGQVAPPEDEVDILDVGRNQCAASTSLV

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=218, Percent_Identity=28.4403669724771, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1787158, Length=170, Percent_Identity=28.2352941176471, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221330176, Length=177, Percent_Identity=26.5536723163842, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 40767; Mature: 40636

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTITPLALFHAINAGDVSEILDVRNIDEFEASKVEANRPVATRNVPVYRVFEDLEAEA
CCCCHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHC
GRTREEAIVICGQGNGSQLVAEEFEDLGRRARSLEGGTDAWNRLLVPIEITGLPGPVRVW
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEEEECCCCCHHHHH
QFLRPAKACLSYVVGVPGQHCIVVDPSRQPQPYLDLASEHGMSVTHVVDTHVHADHVSGG
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEEEECCEEHHCCCCC
PRLAADLGVEYHLPPEDAGGVVPFPNRPLKDGDVLDLGDAQVRVMSMHLPGHTPGTIALL
CCCHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCEEEEE
VSDSVLLVGDTVFVRGLGRPDLTGQADELARDLFRSVHERLRPLPAQTLIAPAHWSTAEE
EECCEEEEECEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCHHH
VNADGLVVTSLADVFTATLLNEKAMERFVEEIVTSLPAAPDSYDTIRRINAGQVAPPEDE
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCC
VDILDVGRNQCAASTSLV
EEHEECCCCHHHHHCCCC
>Mature Secondary Structure 
ADTITPLALFHAINAGDVSEILDVRNIDEFEASKVEANRPVATRNVPVYRVFEDLEAEA
CCCHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHC
GRTREEAIVICGQGNGSQLVAEEFEDLGRRARSLEGGTDAWNRLLVPIEITGLPGPVRVW
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEEEECCCCCHHHHH
QFLRPAKACLSYVVGVPGQHCIVVDPSRQPQPYLDLASEHGMSVTHVVDTHVHADHVSGG
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEEEECCEEHHCCCCC
PRLAADLGVEYHLPPEDAGGVVPFPNRPLKDGDVLDLGDAQVRVMSMHLPGHTPGTIALL
CCCHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCEEEEE
VSDSVLLVGDTVFVRGLGRPDLTGQADELARDLFRSVHERLRPLPAQTLIAPAHWSTAEE
EECCEEEEECEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCHHH
VNADGLVVTSLADVFTATLLNEKAMERFVEEIVTSLPAAPDSYDTIRRINAGQVAPPEDE
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCC
VDILDVGRNQCAASTSLV
EEHEECCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]