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The map label for this gene is hmp [H]

Identifier: 119716837

GI number: 119716837

Start: 2778653

End: 2779249

Strand: Reverse

Name: hmp [H]

Synonym: Noca_2611

Alternate gene names: 119716837

Gene position: 2779249-2778653 (Counterclockwise)

Preceding gene: 119716840

Following gene: 119716836

Centisome position: 55.74

GC content: 75.04

Gene sequence:

>597_bases
GTGGACCACCTGCCCGGGCAGCACTACGTGGTGCGGCTGCGCGCGCCCGACGACTACACCGCCCAGCGGTCGTACTCGGT
CGCCTCCGACCCCGACGACCCGCTGCTGGAGCTGATGGTCGAGTGCCTGCCCGGCGGGGAGGTCTCCGGGTTCCTGTACG
ACGTCGCCGAGGTGGGTGACGTGCTGGAGCTGCGCGGACCGATCGGCGGCTGGTTCGTCTGGGAGGGGGACGTGCCGGCG
CTGTGCCTCGCGGGCGGGTCCGGCGTGGTGCCGGTCGTCGCGATGACCCGCTACGCCCGGCGGCTGGGCCTCCAGGACCG
GCTCCGGGTCGTGGCCGTCGCCCGCACCTGGGACCAGCTCCCCTACGCCGCCGAGCTGAGCCGGCACGGCGCGTTCGTGG
CGCTGACCCGCGAGAACCTGGGCGAGCGGGTCGCGGCCCCGCCGTACCCCTCGGAGCTGGAGGCGTACGCCGCCCGCGCC
GAGCGGGCCTACGTGTGCGGCTCGGTCGGCTTCGCGTCGTACGCCACCCGCCTGCTCGAGGAGGTCGGCGTGGCCACCGA
CACGATCCGCGTCGAGCAGTTCGGCGAGACCGGCTGA

Upstream 100 bases:

>100_bases
AAGCCGCTCGCCTACGTGCTCGCCACCCCGGGGCCGGATCATCGAGATCGACCACCCGACCGACCGCCTGGTCCGGCTGC
GGCTGCACGTCGACGACCGC

Downstream 100 bases:

>100_bases
CGGAGCAGTCCCGGGCTGGGCCGCTCGCTCCCCCGCGCCCGGGCCGGGCTCCGGGGGCGTCGTTTGGTCACCAACGACAG
CCGGGAGCGACCAGGGTCCG

Product: oxidoreductase FAD-binding subunit

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MDHLPGQHYVVRLRAPDDYTAQRSYSVASDPDDPLLELMVECLPGGEVSGFLYDVAEVGDVLELRGPIGGWFVWEGDVPA
LCLAGGSGVVPVVAMTRYARRLGLQDRLRVVAVARTWDQLPYAAELSRHGAFVALTRENLGERVAAPPYPSELEAYAARA
ERAYVCGSVGFASYATRLLEEVGVATDTIRVEQFGETG

Sequences:

>Translated_198_residues
MDHLPGQHYVVRLRAPDDYTAQRSYSVASDPDDPLLELMVECLPGGEVSGFLYDVAEVGDVLELRGPIGGWFVWEGDVPA
LCLAGGSGVVPVVAMTRYARRLGLQDRLRVVAVARTWDQLPYAAELSRHGAFVALTRENLGERVAAPPYPSELEAYAARA
ERAYVCGSVGFASYATRLLEEVGVATDTIRVEQFGETG
>Mature_198_residues
MDHLPGQHYVVRLRAPDDYTAQRSYSVASDPDDPLLELMVECLPGGEVSGFLYDVAEVGDVLELRGPIGGWFVWEGDVPA
LCLAGGSGVVPVVAMTRYARRLGLQDRLRVVAVARTWDQLPYAAELSRHGAFVALTRENLGERVAAPPYPSELEAYAARA
ERAYVCGSVGFASYATRLLEEVGVATDTIRVEQFGETG

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=211, Percent_Identity=29.8578199052133, Blast_Score=74, Evalue=6e-15,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 21502; Mature: 21502

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHLPGQHYVVRLRAPDDYTAQRSYSVASDPDDPLLELMVECLPGGEVSGFLYDVAEVGD
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
VLELRGPIGGWFVWEGDVPALCLAGGSGVVPVVAMTRYARRLGLQDRLRVVAVARTWDQL
HHHHCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
PYAAELSRHGAFVALTRENLGERVAAPPYPSELEAYAARAERAYVCGSVGFASYATRLLE
CCHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHH
EVGVATDTIRVEQFGETG
HHCCCCCEEEEECCCCCC
>Mature Secondary Structure
MDHLPGQHYVVRLRAPDDYTAQRSYSVASDPDDPLLELMVECLPGGEVSGFLYDVAEVGD
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
VLELRGPIGGWFVWEGDVPALCLAGGSGVVPVVAMTRYARRLGLQDRLRVVAVARTWDQL
HHHHCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
PYAAELSRHGAFVALTRENLGERVAAPPYPSELEAYAARAERAYVCGSVGFASYATRLLE
CCHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHH
EVGVATDTIRVEQFGETG
HHCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]