Click here to switch to the map view.

The map label for this gene is ycbL [H]

Identifier: 119716748

GI number: 119716748

Start: 2688838

End: 2689530

Strand: Reverse

Name: ycbL [H]

Synonym: Noca_2522

Alternate gene names: 119716748

Gene position: 2689530-2688838 (Counterclockwise)

Preceding gene: 119716749

Following gene: 119716743

Centisome position: 53.94

GC content: 72.73

Gene sequence:

>693_bases
ATGACCGAGGCGCACGACTACACCGGGGCGGTGCGGCCCGGCGGGCCGCCTGACGTACGCACGCTGGCGCACCTGTCGAT
CACCAAGGTCGCCGTCGACGAGCAGATGTCGAACAACTGCTACCTGCTGCGCTGCCGGGAGACGGGCGCCCAGCTCCTCG
TCGACGCGGCAGCCGAGCCCGCGACGCTGCTGCCGCTCATCGGGGAGACGGGCCTGACGGCTGTCGTCACGACCCACCAG
CACTGGGACCACCACCGGGCGCTCGCCGACATCGTCGCGGCCACCGGCGCGGAGGTGGTCGTCGGCCTACCCGACGCCGC
GGCCGTCACCGAGCAGACCGGGGTCGAGGTGACCCGCACGGTCTCCGAGGGCGACACCGTGGCCGTCGGCACGTGCACGC
TCCAGGTGATCACGATCGCCGGCCACACCCCCGGATCGGTCGCGCTGCTGTACGACGACACCGCGTCCGAGGGCGGTCGC
CCCCACCTGTTCACCGGCGACTCGCTGTTCCCGGGCGGCGTCGGCAACACGTTCGGCGACGAGGCGGCCTTCGCCCAGCT
CATCGACGACGTCGAGACGAAGATCTTCCAGCGGCTCCCCGACGACACCTGGTTCTACCCCGGCCACGGGGACGACTCCA
CGCTCGGCGCCGAGCGTCCGCACCTCGGCGAGTGGCGCGCCCGCGGCTGGTGA

Upstream 100 bases:

>100_bases
CGGGCACCGCGGCCGACCTCGCGTGGTGGCTCACCGGTCGAGGAGCCGGCGAGGGGCTGACCAGCGACGGCGGCGAGCTC
CCGCGGATCGAGGAGTGGTG

Downstream 100 bases:

>100_bases
GCTCGGTGCCCGTCCTCAGGCCGGCCACCAGCCTCAGAACGCCACGTGCGGCCAGTCGCCGAAGCCGCTCAGGTCGTCCG
GCACCCTTCCGGTCTGTCGG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTEAHDYTGAVRPGGPPDVRTLAHLSITKVAVDEQMSNNCYLLRCRETGAQLLVDAAAEPATLLPLIGETGLTAVVTTHQ
HWDHHRALADIVAATGAEVVVGLPDAAAVTEQTGVEVTRTVSEGDTVAVGTCTLQVITIAGHTPGSVALLYDDTASEGGR
PHLFTGDSLFPGGVGNTFGDEAAFAQLIDDVETKIFQRLPDDTWFYPGHGDDSTLGAERPHLGEWRARGW

Sequences:

>Translated_230_residues
MTEAHDYTGAVRPGGPPDVRTLAHLSITKVAVDEQMSNNCYLLRCRETGAQLLVDAAAEPATLLPLIGETGLTAVVTTHQ
HWDHHRALADIVAATGAEVVVGLPDAAAVTEQTGVEVTRTVSEGDTVAVGTCTLQVITIAGHTPGSVALLYDDTASEGGR
PHLFTGDSLFPGGVGNTFGDEAAFAQLIDDVETKIFQRLPDDTWFYPGHGDDSTLGAERPHLGEWRARGW
>Mature_229_residues
TEAHDYTGAVRPGGPPDVRTLAHLSITKVAVDEQMSNNCYLLRCRETGAQLLVDAAAEPATLLPLIGETGLTAVVTTHQH
WDHHRALADIVAATGAEVVVGLPDAAAVTEQTGVEVTRTVSEGDTVAVGTCTLQVITIAGHTPGSVALLYDDTASEGGRP
HLFTGDSLFPGGVGNTFGDEAAFAQLIDDVETKIFQRLPDDTWFYPGHGDDSTLGAERPHLGEWRARGW

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI46361987, Length=185, Percent_Identity=28.1081081081081, Blast_Score=64, Evalue=8e-11,
Organism=Homo sapiens, GI41327741, Length=174, Percent_Identity=32.183908045977, Blast_Score=64, Evalue=9e-11,
Organism=Homo sapiens, GI14150041, Length=185, Percent_Identity=28.1081081081081, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787158, Length=201, Percent_Identity=35.3233830845771, Blast_Score=99, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17538952, Length=192, Percent_Identity=26.5625, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI221330176, Length=181, Percent_Identity=29.8342541436464, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 24334; Mature: 24203

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAHDYTGAVRPGGPPDVRTLAHLSITKVAVDEQMSNNCYLLRCRETGAQLLVDAAAEP
CCCCCCCCCCCCCCCCCCHHHHHHHHHEEEEEHHHCCCCEEEEEECCCCCEEEEECCCCC
ATLLPLIGETGLTAVVTTHQHWDHHRALADIVAATGAEVVVGLPDAAAVTEQTGVEVTRT
CEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCEEEEE
VSEGDTVAVGTCTLQVITIAGHTPGSVALLYDDTASEGGRPHLFTGDSLFPGGVGNTFGD
ECCCCEEEEEEEEEEEEEEECCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCC
EAAFAQLIDDVETKIFQRLPDDTWFYPGHGDDSTLGAERPHLGEWRARGW
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEAHDYTGAVRPGGPPDVRTLAHLSITKVAVDEQMSNNCYLLRCRETGAQLLVDAAAEP
CCCCCCCCCCCCCCCCCHHHHHHHHHEEEEEHHHCCCCEEEEEECCCCCEEEEECCCCC
ATLLPLIGETGLTAVVTTHQHWDHHRALADIVAATGAEVVVGLPDAAAVTEQTGVEVTRT
CEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCEEEEE
VSEGDTVAVGTCTLQVITIAGHTPGSVALLYDDTASEGGRPHLFTGDSLFPGGVGNTFGD
ECCCCEEEEEEEEEEEEEEECCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCC
EAAFAQLIDDVETKIFQRLPDDTWFYPGHGDDSTLGAERPHLGEWRARGW
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]