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The map label for this gene is sir1 [H]

Identifier: 119716578

GI number: 119716578

Start: 2503374

End: 2505095

Strand: Reverse

Name: sir1 [H]

Synonym: Noca_2351

Alternate gene names: 119716578

Gene position: 2505095-2503374 (Counterclockwise)

Preceding gene: 119716580

Following gene: 119716577

Centisome position: 50.24

GC content: 70.5

Gene sequence:

>1722_bases
ATGACTGACCTGCGCTACACCGTCCAGCCCGCCAGCAGCACCGAGATCCCGCGTCCCAAGCGGGCCGAGGGCCAGTGGGC
CCTCGGCCTCCGCGAGCCGCTCAACGCCAACGAGCAGCAGAAGAAGGACGACAGTCCGCTCAACGTGCGCGACCGGATCG
TGAACGTCTACAGCAAGCGCGGGTTCGACTCCATCGACCCCGCCGACCTGCGCGGCCGGTTCCGCTGGTACGGCATCTAC
ACCCAGCGTCGCCCCGGGCTCGACGGCGGCAAGACCGGAGCCCTCGAGCCGCACGAGCTCGACGACCGCTACTTCATGAT
GCGGGTGCGCAGCGACGGGGCACTGCTCGGCGCCGAGCAGCTGCGGACGCTCGGCGGCATCTCCACCGACTTCGCCCGGG
ACACCGCCGACATCACCGACCGGCAGAACATCCAGTACCACTGGATCGACATCGTCGACGTCCCGGAGATCTGGGACCGC
CTCGCCCGCGTCGGGCTGACCACCGAGGAGGCCTGCGGCGACTCCCCCCGTGGGTTCCTCGGCTCCCCGGTCGCCGGCGT
CGCCAAGGACGAGATCATCGACGGGACCCCGGCCCTGTTGGAGATCGGCCGCCGGCGCGCGGGCAACCCCGACTACGCCA
ACCTCCCCCGCAAGTTCAAGACCTCCGTCTCCGGGCACCCCTCGCTCGACGCGACGCCGGAGATCAACGACGTCGCGTTC
GTCGGCGTGGTGCACCCCGAGCTCGGCGCCGGCTTCGACCTGTGGGTCGGCGGCTCCCTGTCGACCAACCCCTTCCTGTC
CGCCAAGATGGGCGTCTGGATCCCGCTCGACGAGGTCGCCGACGTGTGGGAGGGCGTGATCTCGATCTTCCGGGACTACG
GCTACCGGCGCCTCCGGTCCCGGGCCCGGCTCAAGTTCCTCGTCCAGGACTGGGGCATCGAGAAGTTCCGCGAGGTGCTC
GAGAACGAGTACCTCCACCGCCGGCTCCCCGACTGCGCGTCGCCGGAGGTCGCGGCCGGCAACGGCGACCACATCGGCGT
GCACGAGCAGAAGGACGGCCGGTTCTACGTCGGCGCGAGCGCGACCGTGGGACGCGTGAGCGGCAGCCTGCTGAGCCGGC
TCGGCGACCTGGTCGAGAAGTACGGCGTGGACGGGGTCCGGCTCACGGCGTACCAGAAACTCGTGATCCTCGGCGTCGAC
GGCGCCCGGGTCGACGAGCTGCTCGACGACCTGGAGCTGATCGGCCTGTCCGCGCGCCCCTCCCCATGGCGGCGCTCCAC
GATGGCCTGCACCGGCATCGAGTTCTGCAAGCTGGCGATCGTCGAGACCAAGCATCGGGCCAGCGCCCTGGTCGACGAGC
TGGAGCGGCGCTTCCCCGACCTCGACACGCCGATCACCGTCAACGTGAACGGGTGCCCGAATGCCTGCGCGCGTACCCAG
GTCGCGGACATCGGGCTCAAGGGCCAGCTCGTCCTGCACGAGGGCGAGCAGGTCGAGGGCTTCCAGGTGCACCTGGGCGG
TGGCATCGGGCTCACCCAGCGGCTGGGCCGCAAGCTGCGCGCGCACAAGGTCACCAGCGCCGGGCTCGACGACTACATCA
CCTCGGTCGTCACCAACTACCTCACCGACCGCACCGACGGCGAGGCGTTCGCCGCCTGGGTCGAGCGCGCCGACGAGGAG
CTGCTGCGCGGCGACAAGACCCTGGAGGCGGTGGCGACATGA

Upstream 100 bases:

>100_bases
CGCCCACCGCGCAGCTGACCGCACCGGTTGACCGCAGGCCCCGACGACGTGGCCGCCCCCGGTTCGATGGTCGCTCGCAC
CGTCGCTTCAGGAAGCCCCG

Downstream 100 bases:

>100_bases
GCGAGCGCGCCGTCCCCTTCCACTGCCCCTACTGCGGGGAGGAGGACCTGCGCCCGCACGAGGTCCTCTCGGAGAACGGC
GAGGTCCACTCGCCCCACGG

Product: ferredoxin--nitrite reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MTDLRYTVQPASSTEIPRPKRAEGQWALGLREPLNANEQQKKDDSPLNVRDRIVNVYSKRGFDSIDPADLRGRFRWYGIY
TQRRPGLDGGKTGALEPHELDDRYFMMRVRSDGALLGAEQLRTLGGISTDFARDTADITDRQNIQYHWIDIVDVPEIWDR
LARVGLTTEEACGDSPRGFLGSPVAGVAKDEIIDGTPALLEIGRRRAGNPDYANLPRKFKTSVSGHPSLDATPEINDVAF
VGVVHPELGAGFDLWVGGSLSTNPFLSAKMGVWIPLDEVADVWEGVISIFRDYGYRRLRSRARLKFLVQDWGIEKFREVL
ENEYLHRRLPDCASPEVAAGNGDHIGVHEQKDGRFYVGASATVGRVSGSLLSRLGDLVEKYGVDGVRLTAYQKLVILGVD
GARVDELLDDLELIGLSARPSPWRRSTMACTGIEFCKLAIVETKHRASALVDELERRFPDLDTPITVNVNGCPNACARTQ
VADIGLKGQLVLHEGEQVEGFQVHLGGGIGLTQRLGRKLRAHKVTSAGLDDYITSVVTNYLTDRTDGEAFAAWVERADEE
LLRGDKTLEAVAT

Sequences:

>Translated_573_residues
MTDLRYTVQPASSTEIPRPKRAEGQWALGLREPLNANEQQKKDDSPLNVRDRIVNVYSKRGFDSIDPADLRGRFRWYGIY
TQRRPGLDGGKTGALEPHELDDRYFMMRVRSDGALLGAEQLRTLGGISTDFARDTADITDRQNIQYHWIDIVDVPEIWDR
LARVGLTTEEACGDSPRGFLGSPVAGVAKDEIIDGTPALLEIGRRRAGNPDYANLPRKFKTSVSGHPSLDATPEINDVAF
VGVVHPELGAGFDLWVGGSLSTNPFLSAKMGVWIPLDEVADVWEGVISIFRDYGYRRLRSRARLKFLVQDWGIEKFREVL
ENEYLHRRLPDCASPEVAAGNGDHIGVHEQKDGRFYVGASATVGRVSGSLLSRLGDLVEKYGVDGVRLTAYQKLVILGVD
GARVDELLDDLELIGLSARPSPWRRSTMACTGIEFCKLAIVETKHRASALVDELERRFPDLDTPITVNVNGCPNACARTQ
VADIGLKGQLVLHEGEQVEGFQVHLGGGIGLTQRLGRKLRAHKVTSAGLDDYITSVVTNYLTDRTDGEAFAAWVERADEE
LLRGDKTLEAVAT
>Mature_572_residues
TDLRYTVQPASSTEIPRPKRAEGQWALGLREPLNANEQQKKDDSPLNVRDRIVNVYSKRGFDSIDPADLRGRFRWYGIYT
QRRPGLDGGKTGALEPHELDDRYFMMRVRSDGALLGAEQLRTLGGISTDFARDTADITDRQNIQYHWIDIVDVPEIWDRL
ARVGLTTEEACGDSPRGFLGSPVAGVAKDEIIDGTPALLEIGRRRAGNPDYANLPRKFKTSVSGHPSLDATPEINDVAFV
GVVHPELGAGFDLWVGGSLSTNPFLSAKMGVWIPLDEVADVWEGVISIFRDYGYRRLRSRARLKFLVQDWGIEKFREVLE
NEYLHRRLPDCASPEVAAGNGDHIGVHEQKDGRFYVGASATVGRVSGSLLSRLGDLVEKYGVDGVRLTAYQKLVILGVDG
ARVDELLDDLELIGLSARPSPWRRSTMACTGIEFCKLAIVETKHRASALVDELERRFPDLDTPITVNVNGCPNACARTQV
ADIGLKGQLVLHEGEQVEGFQVHLGGGIGLTQRLGRKLRAHKVTSAGLDDYITSVVTNYLTDRTDGEAFAAWVERADEEL
LRGDKTLEAVAT

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Escherichia coli, GI1789122, Length=526, Percent_Identity=25.6653992395437, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6322597, Length=560, Percent_Identity=26.0714285714286, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 63330; Mature: 63199

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLRYTVQPASSTEIPRPKRAEGQWALGLREPLNANEQQKKDDSPLNVRDRIVNVYSKR
CCCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHC
GFDSIDPADLRGRFRWYGIYTQRRPGLDGGKTGALEPHELDDRYFMMRVRSDGALLGAEQ
CCCCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEECHHH
LRTLGGISTDFARDTADITDRQNIQYHWIDIVDVPEIWDRLARVGLTTEEACGDSPRGFL
HHHHCCCCHHHHCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHCCCCCHHHCCCCCCCCC
GSPVAGVAKDEIIDGTPALLEIGRRRAGNPDYANLPRKFKTSVSGHPSLDATPEINDVAF
CCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCHHCCCHHHHHCCCCCCCCCCCCCCCCEEE
VGVVHPELGAGFDLWVGGSLSTNPFLSAKMGVWIPLDEVADVWEGVISIFRDYGYRRLRS
EEEECCCCCCCEEEEECCCCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
RARLKFLVQDWGIEKFREVLENEYLHRRLPDCASPEVAAGNGDHIGVHEQKDGRFYVGAS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCEECCCCCEEEECC
ATVGRVSGSLLSRLGDLVEKYGVDGVRLTAYQKLVILGVDGARVDELLDDLELIGLSARP
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCC
SPWRRSTMACTGIEFCKLAIVETKHRASALVDELERRFPDLDTPITVNVNGCPNACARTQ
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHH
VADIGLKGQLVLHEGEQVEGFQVHLGGGIGLTQRLGRKLRAHKVTSAGLDDYITSVVTNY
HHHCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LTDRTDGEAFAAWVERADEELLRGDKTLEAVAT
HCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
TDLRYTVQPASSTEIPRPKRAEGQWALGLREPLNANEQQKKDDSPLNVRDRIVNVYSKR
CCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHC
GFDSIDPADLRGRFRWYGIYTQRRPGLDGGKTGALEPHELDDRYFMMRVRSDGALLGAEQ
CCCCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEECHHH
LRTLGGISTDFARDTADITDRQNIQYHWIDIVDVPEIWDRLARVGLTTEEACGDSPRGFL
HHHHCCCCHHHHCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHCCCCCHHHCCCCCCCCC
GSPVAGVAKDEIIDGTPALLEIGRRRAGNPDYANLPRKFKTSVSGHPSLDATPEINDVAF
CCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCHHCCCHHHHHCCCCCCCCCCCCCCCCEEE
VGVVHPELGAGFDLWVGGSLSTNPFLSAKMGVWIPLDEVADVWEGVISIFRDYGYRRLRS
EEEECCCCCCCEEEEECCCCCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
RARLKFLVQDWGIEKFREVLENEYLHRRLPDCASPEVAAGNGDHIGVHEQKDGRFYVGAS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCEECCCCCEEEECC
ATVGRVSGSLLSRLGDLVEKYGVDGVRLTAYQKLVILGVDGARVDELLDDLELIGLSARP
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCC
SPWRRSTMACTGIEFCKLAIVETKHRASALVDELERRFPDLDTPITVNVNGCPNACARTQ
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHH
VADIGLKGQLVLHEGEQVEGFQVHLGGGIGLTQRLGRKLRAHKVTSAGLDDYITSVVTNY
HHHCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LTDRTDGEAFAAWVERADEELLRGDKTLEAVAT
HCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA