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The map label for this gene is cysH [H]

Identifier: 119716576

GI number: 119716576

Start: 2502437

End: 2503183

Strand: Reverse

Name: cysH [H]

Synonym: Noca_2349

Alternate gene names: 119716576

Gene position: 2503183-2502437 (Counterclockwise)

Preceding gene: 119716577

Following gene: 119716575

Centisome position: 50.21

GC content: 71.08

Gene sequence:

>747_bases
ATGACCGCGGCGACCACGAACTCGGCTCGCAACTTCCGTGGCATCGAGACCGCTGGCCGCTCCTCCGAGGAGCTGCGCGA
GCTGGTGTCCCACTGGGGCGCCGAGCTCGAGCTCGCGCCCGCCGAGGACATCGTCGAGTGGGCGGTGGCGACCTTCGGCG
AGAGGTTCTGCGTGACGTCGTCGATGGCGGATGCCGTCCTCGCGCACCTGGTCTCCCGCGTCGCGCCGGGGATCGACGTG
CTCTTCCTGGACACCGGCTACCACTTCGCCGAGACGATCGGGACCCGGGACGCGGTCCAGGCGACGCTGCCGGTCAACCT
GATCACGATCACCCCGGTGCAGTCGGTCGCCGAGCAGGACGCGGCGTACGGCACGGACCTCTACAAGACCGACCCCGACC
TGTGCTGCGCGCTGCGCAAGGTGCAGCCGCTCGCGGACGCCCTCGAGGGGTACGACGCGTGGGCGACCGGGCTGCGCCGC
GCCGAGACCCAGCACCGCGTGATCGCCCCGGTCATCGGCTGGGACGCCAAGCGCGGCAAGGTCAAGGTCTCGCCGCTGGC
ACGCTGGACCGACGAGGAGATCGAGCGCTACATCGCCGACCACGACGTGCTGGTGAACCCGCTCGCGTACGACGGCTACC
CGTCCATCGGCTGCTGGCCCTGCACACGCCGCGTGGCTCCCGGCGAGGACCCACGCAGCGGCCGTTGGGCCGGCACCACC
AAGACCGAGTGCGGGATCCACTCATGA

Upstream 100 bases:

>100_bases
CGCCCCACGGCACCTGGGAGTGCCGCGCCTGCCTGCGCGCCTTCTCCCTGAAGATGCTCGGTCTGGTCCGCCCCTCGACC
GCTGCACCGGGAGCGCCGTC

Downstream 100 bases:

>100_bases
CCCGGATCCCGCACCCCAGCCCGGCCGACAGCGTGGCCGACCGCGGCTTGCCCGAGATGCACTCCCCCGCACCAACCGCA
CGCACACGTAAGGAGGCGGC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTAATTNSARNFRGIETAGRSSEELRELVSHWGAELELAPAEDIVEWAVATFGERFCVTSSMADAVLAHLVSRVAPGIDV
LFLDTGYHFAETIGTRDAVQATLPVNLITITPVQSVAEQDAAYGTDLYKTDPDLCCALRKVQPLADALEGYDAWATGLRR
AETQHRVIAPVIGWDAKRGKVKVSPLARWTDEEIERYIADHDVLVNPLAYDGYPSIGCWPCTRRVAPGEDPRSGRWAGTT
KTECGIHS

Sequences:

>Translated_248_residues
MTAATTNSARNFRGIETAGRSSEELRELVSHWGAELELAPAEDIVEWAVATFGERFCVTSSMADAVLAHLVSRVAPGIDV
LFLDTGYHFAETIGTRDAVQATLPVNLITITPVQSVAEQDAAYGTDLYKTDPDLCCALRKVQPLADALEGYDAWATGLRR
AETQHRVIAPVIGWDAKRGKVKVSPLARWTDEEIERYIADHDVLVNPLAYDGYPSIGCWPCTRRVAPGEDPRSGRWAGTT
KTECGIHS
>Mature_247_residues
TAATTNSARNFRGIETAGRSSEELRELVSHWGAELELAPAEDIVEWAVATFGERFCVTSSMADAVLAHLVSRVAPGIDVL
FLDTGYHFAETIGTRDAVQATLPVNLITITPVQSVAEQDAAYGTDLYKTDPDLCCALRKVQPLADALEGYDAWATGLRRA
ETQHRVIAPVIGWDAKRGKVKVSPLARWTDEEIERYIADHDVLVNPLAYDGYPSIGCWPCTRRVAPGEDPRSGRWAGTTK
TECGIHS

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=222, Percent_Identity=34.6846846846847, Blast_Score=109, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6325425, Length=235, Percent_Identity=32.7659574468085, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27085; Mature: 26953

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAATTNSARNFRGIETAGRSSEELRELVSHWGAELELAPAEDIVEWAVATFGERFCVTS
CCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCHHHHHHH
SMADAVLAHLVSRVAPGIDVLFLDTGYHFAETIGTRDAVQATLPVNLITITPVQSVAEQD
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCHHHHEEECCEEEEEECCHHHHHHHH
AAYGTDLYKTDPDLCCALRKVQPLADALEGYDAWATGLRRAETQHRVIAPVIGWDAKRGK
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEHHHCCCCCCCE
VKVSPLARWTDEEIERYIADHDVLVNPLAYDGYPSIGCWPCTRRVAPGEDPRSGRWAGTT
EEECHHHHCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KTECGIHS
CCCCCCCC
>Mature Secondary Structure 
TAATTNSARNFRGIETAGRSSEELRELVSHWGAELELAPAEDIVEWAVATFGERFCVTS
CCCCCCCCHHCCCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCHHHHHHH
SMADAVLAHLVSRVAPGIDVLFLDTGYHFAETIGTRDAVQATLPVNLITITPVQSVAEQD
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCHHHHEEECCEEEEEECCHHHHHHHH
AAYGTDLYKTDPDLCCALRKVQPLADALEGYDAWATGLRRAETQHRVIAPVIGWDAKRGK
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEHHHCCCCCCCE
VKVSPLARWTDEEIERYIADHDVLVNPLAYDGYPSIGCWPCTRRVAPGEDPRSGRWAGTT
EEECHHHHCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KTECGIHS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]