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The map label for this gene is ubiB [C]

Identifier: 119715209

GI number: 119715209

Start: 1012147

End: 1013484

Strand: Reverse

Name: ubiB [C]

Synonym: Noca_0964

Alternate gene names: 119715209

Gene position: 1013484-1012147 (Counterclockwise)

Preceding gene: 119715211

Following gene: 119715208

Centisome position: 20.33

GC content: 73.92

Gene sequence:

>1338_bases
GTGACCGAGCTGCCCCGCAAGGCCGTCGCCCGGACGGCGAGGCTGGCCGCGCTGCCCCTGGGGTACGCCGGCCGCAGCGC
GGTCGGCCTCGGCAAGCGGCTCGGTGGCGCGCCGGCCGAGACCGTGATGACCGAGATCCAGCAGCGCACGGCCGAGCAGC
TGTTCCGCACCCTCGGGGAGCTCAAGGGCGGCGCGATGAAGGTCGGCCAGATGCTCTCGATCATGGAGTCGGCGCTTCCC
GAGAGCCTCGCCGGCCCCTACCGCGAGCACCTCACCCGGCTCCAGGACGACGCTCCGCCGATGCCGACGCAGACGGTGCG
CGACATCCTCGCCCGCGATCTCGGCCCCGACTGGCGCGAGCAGCTGGTCTGGCTCGACGGCGGCCCGACCGCCGCCGCCT
CGATCGGGCAGGTGCACCGGGGCCGCTGGCACGACGGCCGCGAGGTCGCCGTCAAGGTGCAGTACCCCGGTGCGGCCGAC
GCCCTGCGCTCGGACCTGCGCCAGCTCGCCCGGGTCGCCCGGACCGCGGCACCGCTGGTGCCGGGGCTCGACCTCAAGCC
CCTGGTCGCCGAGCTCCAGGCGCGCGCCGAGGACGAGCTCGACTACCAGCTCGAGGCGGAGGCCCAGGCGACGTTCGCGG
CCGCGTTCCGCGACGACCCGGACATCGTGGTCCCCGACGTGGTGGCGGTCGGCGAGACGGTCCTGGTGACCGAGTGGCTC
GAGAGCCCGGCCTCCCTGGCGTCGATCATCGCCGGCGGCACCCAGGAGGAGCGCGACCACTACGGCGAGCTGCTCGTCCG
GTTCCTCTTCTCCGGCCCGGCCCGGACCGGCATGCTGCACGCCGACCCGCACCCCGGCAACTACCGCATCCTGCCCGGAC
CCGGCGGCGAGCCCGGCCGGCTCGGCGTCCTCGACTTCGGCGCGGTCGCCCGGCTCCCGGAGCGTGGGCTCCCCGAGGCC
ATGGGTCGGCTGCTACGGGTTGCGGCCGTCGAGGACCCCGAGGAGCTGTTGGAGGGGTTGCGCCGCGAGGGCTTCGTCAA
GGACCGGGTCCGGGTCGACCCCCAGCAGCTGCTCGACTACCTGGCGCCGTTCGTCGAGCCGACCAAGGTCGAGCGGTTCC
GGTTCTCGCGGTCCTGGATGCGCAGTCAGTTCGCGCGGATCAACGACCCGCGCGACCCGGCGTACACCGTCGGCATGAAG
ATCAACCTGCCGCCGTCGTACCTGCTGATCCACCGCACCTGGCTGGCCGGCATCGGCGTGCTGAGCCAGCTGGAGTGCGA
GGCGCCGTTCCGGCAGATCCTCACCGAGTCGCTGCCCGGGTTCGCCGATCCGAGCTGA

Upstream 100 bases:

>100_bases
GCTCACCGCTCGACGGTACCCGGCGACGTCCGCCCCATGCAGCGCGGCGGCGCAGCGGCCGCTTCGGTCGCCGCCTTCGG
CCACCTGGGAGAATGGCTGC

Downstream 100 bases:

>100_bases
GCCTCCTCCGAGCCACCCGATGGGGCCATTGCGGGTCGGGCAGGGCGGGCGCACGCTGGGCGGATGGCACTGACCGAGAG
CGCGGTCGCGGTGATGCTCC

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTELPRKAVARTARLAALPLGYAGRSAVGLGKRLGGAPAETVMTEIQQRTAEQLFRTLGELKGGAMKVGQMLSIMESALP
ESLAGPYREHLTRLQDDAPPMPTQTVRDILARDLGPDWREQLVWLDGGPTAAASIGQVHRGRWHDGREVAVKVQYPGAAD
ALRSDLRQLARVARTAAPLVPGLDLKPLVAELQARAEDELDYQLEAEAQATFAAAFRDDPDIVVPDVVAVGETVLVTEWL
ESPASLASIIAGGTQEERDHYGELLVRFLFSGPARTGMLHADPHPGNYRILPGPGGEPGRLGVLDFGAVARLPERGLPEA
MGRLLRVAAVEDPEELLEGLRREGFVKDRVRVDPQQLLDYLAPFVEPTKVERFRFSRSWMRSQFARINDPRDPAYTVGMK
INLPPSYLLIHRTWLAGIGVLSQLECEAPFRQILTESLPGFADPS

Sequences:

>Translated_445_residues
MTELPRKAVARTARLAALPLGYAGRSAVGLGKRLGGAPAETVMTEIQQRTAEQLFRTLGELKGGAMKVGQMLSIMESALP
ESLAGPYREHLTRLQDDAPPMPTQTVRDILARDLGPDWREQLVWLDGGPTAAASIGQVHRGRWHDGREVAVKVQYPGAAD
ALRSDLRQLARVARTAAPLVPGLDLKPLVAELQARAEDELDYQLEAEAQATFAAAFRDDPDIVVPDVVAVGETVLVTEWL
ESPASLASIIAGGTQEERDHYGELLVRFLFSGPARTGMLHADPHPGNYRILPGPGGEPGRLGVLDFGAVARLPERGLPEA
MGRLLRVAAVEDPEELLEGLRREGFVKDRVRVDPQQLLDYLAPFVEPTKVERFRFSRSWMRSQFARINDPRDPAYTVGMK
INLPPSYLLIHRTWLAGIGVLSQLECEAPFRQILTESLPGFADPS
>Mature_444_residues
TELPRKAVARTARLAALPLGYAGRSAVGLGKRLGGAPAETVMTEIQQRTAEQLFRTLGELKGGAMKVGQMLSIMESALPE
SLAGPYREHLTRLQDDAPPMPTQTVRDILARDLGPDWREQLVWLDGGPTAAASIGQVHRGRWHDGREVAVKVQYPGAADA
LRSDLRQLARVARTAAPLVPGLDLKPLVAELQARAEDELDYQLEAEAQATFAAAFRDDPDIVVPDVVAVGETVLVTEWLE
SPASLASIIAGGTQEERDHYGELLVRFLFSGPARTGMLHADPHPGNYRILPGPGGEPGRLGVLDFGAVARLPERGLPEAM
GRLLRVAAVEDPEELLEGLRREGFVKDRVRVDPQQLLDYLAPFVEPTKVERFRFSRSWMRSQFARINDPRDPAYTVGMKI
NLPPSYLLIHRTWLAGIGVLSQLECEAPFRQILTESLPGFADPS

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI34147522, Length=315, Percent_Identity=32.3809523809524, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI27363457, Length=264, Percent_Identity=32.5757575757576, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI40254938, Length=287, Percent_Identity=27.5261324041812, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI217416386, Length=229, Percent_Identity=31.4410480349345, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI41393593, Length=296, Percent_Identity=29.7297297297297, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI217035081, Length=206, Percent_Identity=27.6699029126214, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI2367309, Length=272, Percent_Identity=30.5147058823529, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI32565180, Length=367, Percent_Identity=31.3351498637602, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17559152, Length=312, Percent_Identity=26.2820512820513, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321319, Length=261, Percent_Identity=31.4176245210728, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI18859849, Length=300, Percent_Identity=30, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI22024280, Length=288, Percent_Identity=27.0833333333333, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24662575, Length=283, Percent_Identity=27.208480565371, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 48722; Mature: 48591

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELPRKAVARTARLAALPLGYAGRSAVGLGKRLGGAPAETVMTEIQQRTAEQLFRTLGE
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LKGGAMKVGQMLSIMESALPESLAGPYREHLTRLQDDAPPMPTQTVRDILARDLGPDWRE
HCCCHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHH
QLVWLDGGPTAAASIGQVHRGRWHDGREVAVKVQYPGAADALRSDLRQLARVARTAAPLV
CEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
PGLDLKPLVAELQARAEDELDYQLEAEAQATFAAAFRDDPDIVVPDVVAVGETVLVTEWL
CCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCEECCCHHHHCCHHHHHHHH
ESPASLASIIAGGTQEERDHYGELLVRFLFSGPARTGMLHADPHPGNYRILPGPGGEPGR
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEEEECCCCCCCCE
LGVLDFGAVARLPERGLPEAMGRLLRVAAVEDPEELLEGLRREGFVKDRVRVDPQQLLDY
EEEECHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHH
LAPFVEPTKVERFRFSRSWMRSQFARINDPRDPAYTVGMKINLPPSYLLIHRTWLAGIGV
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
LSQLECEAPFRQILTESLPGFADPS
HHHHHHCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TELPRKAVARTARLAALPLGYAGRSAVGLGKRLGGAPAETVMTEIQQRTAEQLFRTLGE
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LKGGAMKVGQMLSIMESALPESLAGPYREHLTRLQDDAPPMPTQTVRDILARDLGPDWRE
HCCCHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHH
QLVWLDGGPTAAASIGQVHRGRWHDGREVAVKVQYPGAADALRSDLRQLARVARTAAPLV
CEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
PGLDLKPLVAELQARAEDELDYQLEAEAQATFAAAFRDDPDIVVPDVVAVGETVLVTEWL
CCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCEECCCHHHHCCHHHHHHHH
ESPASLASIIAGGTQEERDHYGELLVRFLFSGPARTGMLHADPHPGNYRILPGPGGEPGR
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEEEECCCCCCCCE
LGVLDFGAVARLPERGLPEAMGRLLRVAAVEDPEELLEGLRREGFVKDRVRVDPQQLLDY
EEEECHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHH
LAPFVEPTKVERFRFSRSWMRSQFARINDPRDPAYTVGMKINLPPSYLLIHRTWLAGIGV
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
LSQLECEAPFRQILTESLPGFADPS
HHHHHHCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]