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The map label for this gene is alr [H]

Identifier: 119715145

GI number: 119715145

Start: 940501

End: 941637

Strand: Direct

Name: alr [H]

Synonym: Noca_0900

Alternate gene names: 119715145

Gene position: 940501-941637 (Clockwise)

Preceding gene: 119715144

Following gene: 119715146

Centisome position: 18.86

GC content: 75.81

Gene sequence:

>1137_bases
ATGAACGCCCCACCGGTCGCGCGCGCCGAGATCGTCGTCGATCTCGCGGCGATCCGGAACAACGTCCGCCGGCTCCGCGA
GGTCACCGGGGTCGCCTCGATGACCGTGGTCAAGGCCGACGGCTACGGGCACGGCATGCTGGAGGCCGCTCGGGCCGCGC
GCGAGGCCGGCTCGGAGTGGCTCGGGGTGGCCACCCTCGACGAGGCGGCGGCCCTGCGCGCCGCGGGCGACACCGGCCGG
GTGCTCACCTGGCTGACGGTGCCGGGCGAGGACTACGCCTCCGCGATCGCCGCGGACGTCGACGTCACCGCCTACAGCCC
GGCCGAGCTGGACGAGATCGCTGCCGGCGTGCGAGCCGCCGGCCGTCCGGCCCGGGTCCAGCTCAAGATCGACACCGGGC
TCTCCCGGGGCGGCGCCACCGTCGAGCAGTGGCCGGACCTGGTCGCGGCCGCCCGTGCCGGCGAGGAGGCCGGCCGATGG
CGGGTCACCGGGATCTGGTCCCACTTCGCCTGCAGCGACGAGCCCGACCATCCCGCCAACGCCGCCCAGGAGACGGCCTT
CCGGCACGCTCTCGAGGTCGCCGACCGCGCCGGCCTGCGCCCGGAGGTGCGGCACCTGGCCAACTCCGCGGCCGGGCTGC
TGCGGCCCTCGGCGCGGTTCGACCTGGTGCGGTTCGGGCTCGCGTCGTACGGCCTCGATCCCGCGCCCGGCCACCTCGCC
GAGGCCGACCTCGGGCTCGTCCCGGCGATGACGGCGCGCGCCGTGCTGGTGCTGACCAAGCCGCTGCCCGCCGGCGCCGG
CGTCTCCTACGGGCACACCTGGGTCGCGGACACGCCGACCTCCGTCGGCCTGGTGCCGGTCGGGTACGGCGACGGCATCC
CGCGCCACGCCGGCAACCACGCCCAGGTGCTGGTCGACGGCAAGCGCCGGGCCGTGCGCGGCCAGGTCTGCATGGACCAG
TTCGTGGTCGACCTCGGCGGCGACCTGCTGGAGCCGGGCCACGCGGTGGTGCTCTTCGGGCCCGGGACCGCGGGCGAGCC
GACCGTCCAGGAGTGGGCCGACGCGGCCGGCACCATCTCCTACGAGATCATCAGCAGGATCGGGGGCCGGATGAGCAGGA
GGTACGTCGACTCGTGA

Upstream 100 bases:

>100_bases
CTCGCGGCCCGCCGCGGACCGCTGGTGGCCGGCGACGTGGCCCGCGCCCTCCCGGCGGCCGTCCGCAACCTGCCGGGCTG
GTGATGGGAGAATTGCCGGC

Downstream 100 bases:

>100_bases
GGCTCCGCACGCACCTGATCGGTGCCACCGCGACCGCGGTCGGCATCGCCGCGGGCGCCGGCGCCGGGGTCGCCCGGCAG
CGCCGCGCCATCGCGCGCCG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MNAPPVARAEIVVDLAAIRNNVRRLREVTGVASMTVVKADGYGHGMLEAARAAREAGSEWLGVATLDEAAALRAAGDTGR
VLTWLTVPGEDYASAIAADVDVTAYSPAELDEIAAGVRAAGRPARVQLKIDTGLSRGGATVEQWPDLVAAARAGEEAGRW
RVTGIWSHFACSDEPDHPANAAQETAFRHALEVADRAGLRPEVRHLANSAAGLLRPSARFDLVRFGLASYGLDPAPGHLA
EADLGLVPAMTARAVLVLTKPLPAGAGVSYGHTWVADTPTSVGLVPVGYGDGIPRHAGNHAQVLVDGKRRAVRGQVCMDQ
FVVDLGGDLLEPGHAVVLFGPGTAGEPTVQEWADAAGTISYEIISRIGGRMSRRYVDS

Sequences:

>Translated_378_residues
MNAPPVARAEIVVDLAAIRNNVRRLREVTGVASMTVVKADGYGHGMLEAARAAREAGSEWLGVATLDEAAALRAAGDTGR
VLTWLTVPGEDYASAIAADVDVTAYSPAELDEIAAGVRAAGRPARVQLKIDTGLSRGGATVEQWPDLVAAARAGEEAGRW
RVTGIWSHFACSDEPDHPANAAQETAFRHALEVADRAGLRPEVRHLANSAAGLLRPSARFDLVRFGLASYGLDPAPGHLA
EADLGLVPAMTARAVLVLTKPLPAGAGVSYGHTWVADTPTSVGLVPVGYGDGIPRHAGNHAQVLVDGKRRAVRGQVCMDQ
FVVDLGGDLLEPGHAVVLFGPGTAGEPTVQEWADAAGTISYEIISRIGGRMSRRYVDS
>Mature_378_residues
MNAPPVARAEIVVDLAAIRNNVRRLREVTGVASMTVVKADGYGHGMLEAARAAREAGSEWLGVATLDEAAALRAAGDTGR
VLTWLTVPGEDYASAIAADVDVTAYSPAELDEIAAGVRAAGRPARVQLKIDTGLSRGGATVEQWPDLVAAARAGEEAGRW
RVTGIWSHFACSDEPDHPANAAQETAFRHALEVADRAGLRPEVRHLANSAAGLLRPSARFDLVRFGLASYGLDPAPGHLA
EADLGLVPAMTARAVLVLTKPLPAGAGVSYGHTWVADTPTSVGLVPVGYGDGIPRHAGNHAQVLVDGKRRAVRGQVCMDQ
FVVDLGGDLLEPGHAVVLFGPGTAGEPTVQEWADAAGTISYEIISRIGGRMSRRYVDS

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=380, Percent_Identity=35, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1787439, Length=366, Percent_Identity=31.6939890710383, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39543; Mature: 39543

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPPVARAEIVVDLAAIRNNVRRLREVTGVASMTVVKADGYGHGMLEAARAAREAGSEW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHEEEEEEECCCCCHHHHHHHHHHHCCCCE
LGVATLDEAAALRAAGDTGRVLTWLTVPGEDYASAIAADVDVTAYSPAELDEIAAGVRAA
EEEEEHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHCCEEEECCCHHHHHHHHHHHCC
GRPARVQLKIDTGLSRGGATVEQWPDLVAAARAGEEAGRWRVTGIWSHFACSDEPDHPAN
CCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCHHCCCEEEEEEEEECCCCCCCCCCCC
AAQETAFRHALEVADRAGLRPEVRHLANSAAGLLRPSARFDLVRFGLASYGLDPAPGHLA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC
EADLGLVPAMTARAVLVLTKPLPAGAGVSYGHTWVADTPTSVGLVPVGYGDGIPRHAGNH
CCCCCCCCHHHHCEEEEEECCCCCCCCCCCCCEEECCCCCCCCEEEECCCCCCCCCCCCC
AQVLVDGKRRAVRGQVCMDQFVVDLGGDLLEPGHAVVLFGPGTAGEPTVQEWADAAGTIS
EEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCHH
YEIISRIGGRMSRRYVDS
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNAPPVARAEIVVDLAAIRNNVRRLREVTGVASMTVVKADGYGHGMLEAARAAREAGSEW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHEEEEEEECCCCCHHHHHHHHHHHCCCCE
LGVATLDEAAALRAAGDTGRVLTWLTVPGEDYASAIAADVDVTAYSPAELDEIAAGVRAA
EEEEEHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHCCEEEECCCHHHHHHHHHHHCC
GRPARVQLKIDTGLSRGGATVEQWPDLVAAARAGEEAGRWRVTGIWSHFACSDEPDHPAN
CCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCHHCCCEEEEEEEEECCCCCCCCCCCC
AAQETAFRHALEVADRAGLRPEVRHLANSAAGLLRPSARFDLVRFGLASYGLDPAPGHLA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC
EADLGLVPAMTARAVLVLTKPLPAGAGVSYGHTWVADTPTSVGLVPVGYGDGIPRHAGNH
CCCCCCCCHHHHCEEEEEECCCCCCCCCCCCCEEECCCCCCCCEEEECCCCCCCCCCCCC
AQVLVDGKRRAVRGQVCMDQFVVDLGGDLLEPGHAVVLFGPGTAGEPTVQEWADAAGTIS
EEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCHH
YEIISRIGGRMSRRYVDS
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]