Click here to switch to the map view.

The map label for this gene is citA [H]

Identifier: 119714980

GI number: 119714980

Start: 780896

End: 782002

Strand: Reverse

Name: citA [H]

Synonym: Noca_0733

Alternate gene names: 119714980

Gene position: 782002-780896 (Counterclockwise)

Preceding gene: 119714985

Following gene: 119714977

Centisome position: 15.68

GC content: 71.91

Gene sequence:

>1107_bases
ATGACCGAGGTGCAGCACGGGCTGGAGGGCGTCGTGGCCTTCGAGACCGAGATCGCAGAGCCGGACAAGGAGGGCTCGGC
GCTGCGCTACCGCGGCGTGGACATCGAGGAGCTCGTCGGCCGGGTGCCGTTCGAGAAGGTCTGGGGGCTGCTCATCGACG
GCGGCTACGACCCCGGCCTGCCACCCGCCGAGGCCTACAACATCGCGGTGCACACCGGCGACGTCCGCGTCGACGTGCAG
GCTGCGATCGCGATGCTGGCCCCGGCGTTCGGCTTCCGCGCCACCTATGACATCAGCGACGAGCAGGCCCGCGCGGACCT
CTCGCGGGTCGCGGTGATGGTGCTGTCGTACGCCGCACAGTCGGCTCGCGGCCTGCACCAGCCGGTCGTGCCGCAGACCG
AGGTCGACAAGGGCAGCACCCTGGCCGAGAAGTTCCTGATCCGGTGGAAGGGCGAGGCCGACCCCAAGCACGCCCATGCG
ATCGACGCGTACTGGTCCTCCGCGGCCGAGCACGGGATGAATGCCTCCACGTTCACTGCGCGCGTGATCACCTCGACCGG
TGCCGATGTCGCCGCAGCGTTCTCCGGAGCGATCGGCGCGATGAGCGGACCACTGCACGGCGGCGCCCCCTCCCGCGTGC
TGGGCATGATCGAGGAGGTCGAGAAGCGCGACGGCGACGCCCGGTCCTACGTCAAGGAGCTGCTCGACGACGGCGAGCGG
CTGATGGGCTTCGGCCACCGCGTCTACCGCGCGGAGGACCCCCGGGCCCGGGTGCTGCGGCGTACGGCGAAGGAGCTGGC
CGCCCCGCGCTACGAGGTCGCCGAGGAACTGGAGCGAGCGGCGCTCGCCGAGCTGCGCGAGCGCCGGCCGGACCGGGTCC
TGGAGACCAACGTGGAGTTCTGGGCCGCGATCGTGCTCGACTTCGCCGAGGTGCCCGCGAACATGTTCACCTCGATGTTC
ACCTGCGCCCGCACGGGCGGCTGGTCGGCGCACATCCTCGAGCAGAAGCGCACCGGCCGGCTGATCCGGCCCTCGGCCGT
CTACACCGGGCCGTCGTCACGGCCCGCCTCGGAGGTGGCCGGCTGGCGCGCGGAGTGGGCGCGGTGA

Upstream 100 bases:

>100_bases
AAGAGCAGCGAGATCGAGGTGTCCCATGCCCTCGACCCTAGTCGCGGCCCGGGGCACAATGCCTCGGGCGCTTGCTCGCG
TAGTCCAGCGAAGGAGTCAC

Downstream 100 bases:

>100_bases
GCGAAGTGACGGCCTTGGCCGGGAGGTGCTGAGCACCTCGGACTCGACCGCCGTCGGCAGATCCGCAAGCCCGGCTAGAG
GCGCCCGTCGTACCAGCTGG

Product: citrate synthase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MTEVQHGLEGVVAFETEIAEPDKEGSALRYRGVDIEELVGRVPFEKVWGLLIDGGYDPGLPPAEAYNIAVHTGDVRVDVQ
AAIAMLAPAFGFRATYDISDEQARADLSRVAVMVLSYAAQSARGLHQPVVPQTEVDKGSTLAEKFLIRWKGEADPKHAHA
IDAYWSSAAEHGMNASTFTARVITSTGADVAAAFSGAIGAMSGPLHGGAPSRVLGMIEEVEKRDGDARSYVKELLDDGER
LMGFGHRVYRAEDPRARVLRRTAKELAAPRYEVAEELERAALAELRERRPDRVLETNVEFWAAIVLDFAEVPANMFTSMF
TCARTGGWSAHILEQKRTGRLIRPSAVYTGPSSRPASEVAGWRAEWAR

Sequences:

>Translated_368_residues
MTEVQHGLEGVVAFETEIAEPDKEGSALRYRGVDIEELVGRVPFEKVWGLLIDGGYDPGLPPAEAYNIAVHTGDVRVDVQ
AAIAMLAPAFGFRATYDISDEQARADLSRVAVMVLSYAAQSARGLHQPVVPQTEVDKGSTLAEKFLIRWKGEADPKHAHA
IDAYWSSAAEHGMNASTFTARVITSTGADVAAAFSGAIGAMSGPLHGGAPSRVLGMIEEVEKRDGDARSYVKELLDDGER
LMGFGHRVYRAEDPRARVLRRTAKELAAPRYEVAEELERAALAELRERRPDRVLETNVEFWAAIVLDFAEVPANMFTSMF
TCARTGGWSAHILEQKRTGRLIRPSAVYTGPSSRPASEVAGWRAEWAR
>Mature_367_residues
TEVQHGLEGVVAFETEIAEPDKEGSALRYRGVDIEELVGRVPFEKVWGLLIDGGYDPGLPPAEAYNIAVHTGDVRVDVQA
AIAMLAPAFGFRATYDISDEQARADLSRVAVMVLSYAAQSARGLHQPVVPQTEVDKGSTLAEKFLIRWKGEADPKHAHAI
DAYWSSAAEHGMNASTFTARVITSTGADVAAAFSGAIGAMSGPLHGGAPSRVLGMIEEVEKRDGDARSYVKELLDDGERL
MGFGHRVYRAEDPRARVLRRTAKELAAPRYEVAEELERAALAELRERRPDRVLETNVEFWAAIVLDFAEVPANMFTSMFT
CARTGGWSAHILEQKRTGRLIRPSAVYTGPSSRPASEVAGWRAEWAR

Specific function: Catalyzes The Synthesis Of 2-Methylcitrate From Propionyl-CoA And Oxaloacetate. Also Catalyzes The Condensation Of Oxaloacetate With Acetyl-CoA But With A Lower Specificity. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=210, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1786527, Length=377, Percent_Identity=33.9522546419098, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786939, Length=391, Percent_Identity=29.4117647058824, Blast_Score=129, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 40205; Mature: 40074

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVQHGLEGVVAFETEIAEPDKEGSALRYRGVDIEELVGRVPFEKVWGLLIDGGYDPGL
CCCHHHHHCCEEEEEHHHCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHEECCCCCCC
PPAEAYNIAVHTGDVRVDVQAAIAMLAPAFGFRATYDISDEQARADLSRVAVMVLSYAAQ
CCCHHEEEEEECCCEEEHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
SARGLHQPVVPQTEVDKGSTLAEKFLIRWKGEADPKHAHAIDAYWSSAAEHGMNASTFTA
HHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHEE
RVITSTGADVAAAFSGAIGAMSGPLHGGAPSRVLGMIEEVEKRDGDARSYVKELLDDGER
EEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHH
LMGFGHRVYRAEDPRARVLRRTAKELAAPRYEVAEELERAALAELRERRPDRVLETNVEF
HHHCCHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WAAIVLDFAEVPANMFTSMFTCARTGGWSAHILEQKRTGRLIRPSAVYTGPSSRPASEVA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCEEECCCCCCCHHHHH
GWRAEWAR
CCHHHCCC
>Mature Secondary Structure 
TEVQHGLEGVVAFETEIAEPDKEGSALRYRGVDIEELVGRVPFEKVWGLLIDGGYDPGL
CCHHHHHCCEEEEEHHHCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHEECCCCCCC
PPAEAYNIAVHTGDVRVDVQAAIAMLAPAFGFRATYDISDEQARADLSRVAVMVLSYAAQ
CCCHHEEEEEECCCEEEHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
SARGLHQPVVPQTEVDKGSTLAEKFLIRWKGEADPKHAHAIDAYWSSAAEHGMNASTFTA
HHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHEE
RVITSTGADVAAAFSGAIGAMSGPLHGGAPSRVLGMIEEVEKRDGDARSYVKELLDDGER
EEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHH
LMGFGHRVYRAEDPRARVLRRTAKELAAPRYEVAEELERAALAELRERRPDRVLETNVEF
HHHCCHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WAAIVLDFAEVPANMFTSMFTCARTGGWSAHILEQKRTGRLIRPSAVYTGPSSRPASEVA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCEEECCCCCCCHHHHH
GWRAEWAR
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]