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The map label for this gene is cutL [H]

Identifier: 119714868

GI number: 119714868

Start: 647541

End: 649913

Strand: Reverse

Name: cutL [H]

Synonym: Noca_0612

Alternate gene names: 119714868

Gene position: 649913-647541 (Counterclockwise)

Preceding gene: 119714872

Following gene: 119714867

Centisome position: 13.04

GC content: 63.8

Gene sequence:

>2373_bases
GTGAGTAGACCTGGCGCTTCCGGTGGTCTCGGCCCTTCAGCCAAGCGATACGTGGGACAGCCCGTGCGTCGCCGTGAGGA
CGCGCGGCTCCTGCGGGGAGATGCGCGTTTCGTGGACGATGTCGATATTCACGGGCAGCTGTACATGAGCGTGGTGCGTT
CATCTGAGGCCCATGCGCGCATCGTCTCCGTGGAGCCCTCTGCGGCCCGACGGGCTCCCGGCGTCCGGCTAGTCATCACG
GCTGATGACATCGATGCTGAAGTGCCGCTGGAACAGATCGGCTACCACGAGGTTTACCCGCAGATCGACGACTATCTGCA
CCCGGTCTTCGCCGGTGACCGTGTCCGGTACGTCGGGCAACCCGTCGCCGCCGTCATCGCTGACACGCCGTATCTGGCTG
AAGACGCCGCCGGGCTGGTGGAGGTCACCTACGACCTCCTTCCGCCGGTGCTCGATCCTCAGTACGCCTTGACCGATGAG
GCCGAACCACTCTTCGAGGGGCAGTCCAACGAGGCCGTTCGCATCGTGAAGGCGTACGGCGACGTCGCGGACGCCTTTAA
GAAGGCAGCGCATGTCGTGAAGGGTCGCTACGTGGTCGGTCGTCATTCCGGGGTGCCGATGGAGACGAGAGGGTGCATCG
CAGAGCCCGACCGCGGCCGCAAGCAACTCTTCATGTGGGGGCCGGTCCACACCCACGACTGTCAGCGCCTCATCGCGCAA
GTACTCGAACTCCCGCTCGCGGATCTGCGCATGAAACACGTCGACATCGGAGGGAACTTCGGTGTGAAGGGCGGGGTCTT
TCCGGAATACATCATGGTGGGCTGGGCGGCCATGCGTCTGGGACGTCCTGTCAAGTGGACCGAAGATCGCCTCGAGCACA
TGGTGGCAAACGCTCACGCTCGCGAACAGGTGCACGAAATGGCCGCGGCCTTCGACGCCGACGGGGTCCTGCTGGCTTTG
AAGGACGAGATCTGGCACAACCACGGAGCGTTCATTCGGCAGGCCGAGCCTCTCGTCAGCGACATCACAGTCGGGATGGT
CCCAGGCCCCTACCGAGTGCCGGCGTACGACGGGCTCCTTCACGTCGTGGTGTCCAACAAGACGCCGCTGTCCGCCTACC
GTGCTCCAGGCAGGTACGAAGGGACCTTCGCTCGCGAGCGGCTCCTCGACCTCGCGGCCGAACAGATCGGCATTTCGCAG
GTAGAGATTCGGCGCCGCAATCTGCTGACCGAAGCCGACCTTCCATTCGCGCCGGGCATGGACATCTGTTTCGAGCCCTA
CCACTTCGATTCGGGTGACGTCGTTGACCACTTGGACAAAGCGCTCGAGTCGGCGGGGTTCGACGATTGGGAGCGGGAGG
CGGCAGAGCTCCGAGCGCAGGGCCGCTTAGTCGGCAACGGAATCGGCATGCTGATGGACAAGGCTGGCCTTGGGCTCTAC
GAGACGAGCGCCATCGACGTAGACGCCTCTGGACGGATCAGAGTTCGAACTGGGGCATCTTCCGTCGGACAGGGTATCGA
AACAGTCCTGGCGCAGATCGTTGCCGATGAACTCCAAGTCGATCCAGAGCTCATCGACGTCGTTCACGGTGACACCGAGC
TTGTGCCCGAGGGTGTCGGCTCCTGGTCGAGTCGCTCGACCGTTCTGGCCGGAGGAGCGGCGCGTCAGGCGGCCCTCGAC
ACGCTAGCCAAGGCCAAGAGGCTCGCCAGCGAGATGCTGGAAGCAAATGTGGACGATCTGATCCTCGTCGATGGCCGCAT
CGTGGTGTCCGGGCTCGAGCAGCAGGGGTTGAGTCTCGCCGAGATCGCCGGACGGTGGGACGGATGGTCCGCGAGGTTGG
CCAACGACGAGCCAGGCCTCGGCGCGCAGGCCGTCTACCTGGATGAGCACATGAACTATCCCTACGGGGTCACTCTCGTG
CAGATCGAGATTGATCCCGCCACGGGAGGTCACACCTTGAGGCGTTTCCTTACCAGCACCGAGGCCGGACGAGCGATCAA
TCCAATGACCACCCGCGGCCAAGTGATCGGTGCGGCAGCGCAAGGCATCGGAGGTGCCCTCTACGAGGAGTTCCTGTACG
ACGAATCCGGTCAACCGTTGGCCACGTCCTTCATGGACTACCTTCTGCCGACTTCGCTGGACGTGCCAGATGTCGACTTC
TTCATGACGGAGGACGCGCCTACACCCAACAACCCGTTCGGGGCCAAGGGCTTGGGGGAGGTCGGCCTCATCGCTGTGGG
CGCGGCCATCGCGGGCGCCATAGACGATGCCTTTGGCGAAGGTGTGCGCACGATCAAGGTGCCCGTCCCGCCCGAGACGC
TCTGGCGGAGGTCGCATTCGATCGCGTTCAGTGATGAACCCGAGTCGATGTGA

Upstream 100 bases:

>100_bases
CATCGGGCGGATGCGCTTCTCCCGCCAGCGAGCAGCGGCAGCAACGGCGCCGCGACGACACTTCGTGTCTCGGTACATCG
CACAGAAGTGAGGACGAGCA

Downstream 100 bases:

>100_bases
GTCGCAACACCCGGAAGACGTCAAACGGTGGTCTCGCATTGTCCGGAACCGAATAGCCCAACTCGTTCCCCAGGATCCAC
AGTTGCGTGTCTTTTCGCCG

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 790; Mature: 789

Protein sequence:

>790_residues
MSRPGASGGLGPSAKRYVGQPVRRREDARLLRGDARFVDDVDIHGQLYMSVVRSSEAHARIVSVEPSAARRAPGVRLVIT
ADDIDAEVPLEQIGYHEVYPQIDDYLHPVFAGDRVRYVGQPVAAVIADTPYLAEDAAGLVEVTYDLLPPVLDPQYALTDE
AEPLFEGQSNEAVRIVKAYGDVADAFKKAAHVVKGRYVVGRHSGVPMETRGCIAEPDRGRKQLFMWGPVHTHDCQRLIAQ
VLELPLADLRMKHVDIGGNFGVKGGVFPEYIMVGWAAMRLGRPVKWTEDRLEHMVANAHAREQVHEMAAAFDADGVLLAL
KDEIWHNHGAFIRQAEPLVSDITVGMVPGPYRVPAYDGLLHVVVSNKTPLSAYRAPGRYEGTFARERLLDLAAEQIGISQ
VEIRRRNLLTEADLPFAPGMDICFEPYHFDSGDVVDHLDKALESAGFDDWEREAAELRAQGRLVGNGIGMLMDKAGLGLY
ETSAIDVDASGRIRVRTGASSVGQGIETVLAQIVADELQVDPELIDVVHGDTELVPEGVGSWSSRSTVLAGGAARQAALD
TLAKAKRLASEMLEANVDDLILVDGRIVVSGLEQQGLSLAEIAGRWDGWSARLANDEPGLGAQAVYLDEHMNYPYGVTLV
QIEIDPATGGHTLRRFLTSTEAGRAINPMTTRGQVIGAAAQGIGGALYEEFLYDESGQPLATSFMDYLLPTSLDVPDVDF
FMTEDAPTPNNPFGAKGLGEVGLIAVGAAIAGAIDDAFGEGVRTIKVPVPPETLWRRSHSIAFSDEPESM

Sequences:

>Translated_790_residues
MSRPGASGGLGPSAKRYVGQPVRRREDARLLRGDARFVDDVDIHGQLYMSVVRSSEAHARIVSVEPSAARRAPGVRLVIT
ADDIDAEVPLEQIGYHEVYPQIDDYLHPVFAGDRVRYVGQPVAAVIADTPYLAEDAAGLVEVTYDLLPPVLDPQYALTDE
AEPLFEGQSNEAVRIVKAYGDVADAFKKAAHVVKGRYVVGRHSGVPMETRGCIAEPDRGRKQLFMWGPVHTHDCQRLIAQ
VLELPLADLRMKHVDIGGNFGVKGGVFPEYIMVGWAAMRLGRPVKWTEDRLEHMVANAHAREQVHEMAAAFDADGVLLAL
KDEIWHNHGAFIRQAEPLVSDITVGMVPGPYRVPAYDGLLHVVVSNKTPLSAYRAPGRYEGTFARERLLDLAAEQIGISQ
VEIRRRNLLTEADLPFAPGMDICFEPYHFDSGDVVDHLDKALESAGFDDWEREAAELRAQGRLVGNGIGMLMDKAGLGLY
ETSAIDVDASGRIRVRTGASSVGQGIETVLAQIVADELQVDPELIDVVHGDTELVPEGVGSWSSRSTVLAGGAARQAALD
TLAKAKRLASEMLEANVDDLILVDGRIVVSGLEQQGLSLAEIAGRWDGWSARLANDEPGLGAQAVYLDEHMNYPYGVTLV
QIEIDPATGGHTLRRFLTSTEAGRAINPMTTRGQVIGAAAQGIGGALYEEFLYDESGQPLATSFMDYLLPTSLDVPDVDF
FMTEDAPTPNNPFGAKGLGEVGLIAVGAAIAGAIDDAFGEGVRTIKVPVPPETLWRRSHSIAFSDEPESM
>Mature_789_residues
SRPGASGGLGPSAKRYVGQPVRRREDARLLRGDARFVDDVDIHGQLYMSVVRSSEAHARIVSVEPSAARRAPGVRLVITA
DDIDAEVPLEQIGYHEVYPQIDDYLHPVFAGDRVRYVGQPVAAVIADTPYLAEDAAGLVEVTYDLLPPVLDPQYALTDEA
EPLFEGQSNEAVRIVKAYGDVADAFKKAAHVVKGRYVVGRHSGVPMETRGCIAEPDRGRKQLFMWGPVHTHDCQRLIAQV
LELPLADLRMKHVDIGGNFGVKGGVFPEYIMVGWAAMRLGRPVKWTEDRLEHMVANAHAREQVHEMAAAFDADGVLLALK
DEIWHNHGAFIRQAEPLVSDITVGMVPGPYRVPAYDGLLHVVVSNKTPLSAYRAPGRYEGTFARERLLDLAAEQIGISQV
EIRRRNLLTEADLPFAPGMDICFEPYHFDSGDVVDHLDKALESAGFDDWEREAAELRAQGRLVGNGIGMLMDKAGLGLYE
TSAIDVDASGRIRVRTGASSVGQGIETVLAQIVADELQVDPELIDVVHGDTELVPEGVGSWSSRSTVLAGGAARQAALDT
LAKAKRLASEMLEANVDDLILVDGRIVVSGLEQQGLSLAEIAGRWDGWSARLANDEPGLGAQAVYLDEHMNYPYGVTLVQ
IEIDPATGGHTLRRFLTSTEAGRAINPMTTRGQVIGAAAQGIGGALYEEFLYDESGQPLATSFMDYLLPTSLDVPDVDFF
MTEDAPTPNNPFGAKGLGEVGLIAVGAAIAGAIDDAFGEGVRTIKVPVPPETLWRRSHSIAFSDEPESM

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=778, Percent_Identity=25.1928020565553, Blast_Score=187, Evalue=5e-47,
Organism=Homo sapiens, GI71773480, Length=785, Percent_Identity=25.4777070063694, Blast_Score=180, Evalue=4e-45,
Organism=Escherichia coli, GI1789230, Length=763, Percent_Identity=28.4403669724771, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1789246, Length=809, Percent_Identity=25.2163164400494, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1786478, Length=772, Percent_Identity=26.8134715025907, Blast_Score=159, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI17540638, Length=776, Percent_Identity=23.5824742268041, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17539860, Length=772, Percent_Identity=21.7616580310881, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32566215, Length=772, Percent_Identity=21.5025906735751, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17737937, Length=772, Percent_Identity=24.740932642487, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24647195, Length=816, Percent_Identity=25, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24647199, Length=805, Percent_Identity=23.7267080745342, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24647197, Length=781, Percent_Identity=24.7119078104994, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24647193, Length=787, Percent_Identity=23.7611181702668, Blast_Score=123, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24647201, Length=809, Percent_Identity=22.991347342398, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 85534; Mature: 85402

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPGASGGLGPSAKRYVGQPVRRREDARLLRGDARFVDDVDIHGQLYMSVVRSSEAHAR
CCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEE
IVSVEPSAARRAPGVRLVITADDIDAEVPLEQIGYHEVYPQIDDYLHPVFAGDRVRYVGQ
EEEECCHHHHCCCCEEEEEEECCCCCCCCHHHCCCHHHCCCHHHHHCHHHCCCEEEECCC
PVAAVIADTPYLAEDAAGLVEVTYDLLPPVLDPQYALTDEAEPLFEGQSNEAVRIVKAYG
CHHHHHCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEHHHH
DVADAFKKAAHVVKGRYVVGRHSGVPMETRGCIAEPDRGRKQLFMWGPVHTHDCQRLIAQ
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHH
VLELPLADLRMKHVDIGGNFGVKGGVFPEYIMVGWAAMRLGRPVKWTEDRLEHMVANAHA
HHHCCHHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
REQVHEMAAAFDADGVLLALKDEIWHNHGAFIRQAEPLVSDITVGMVPGPYRVPAYDGLL
HHHHHHHHHHCCCCCEEEEEEHHHHCCCCCHHECCCHHHHHCEEEECCCCCCCCCCCCEE
HVVVSNKTPLSAYRAPGRYEGTFARERLLDLAAEQIGISQVEIRRRNLLTEADLPFAPGM
EEEECCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCC
DICFEPYHFDSGDVVDHLDKALESAGFDDWEREAAELRAQGRLVGNGIGMLMDKAGLGLY
CCEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCHHHHHHHCCCCEE
ETSAIDVDASGRIRVRTGASSVGQGIETVLAQIVADELQVDPELIDVVHGDTELVPEGVG
ECCEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHCCCCCC
SWSSRSTVLAGGAARQAALDTLAKAKRLASEMLEANVDDLILVDGRIVVSGLEQQGLSLA
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEECHHHHCCHHH
EIAGRWDGWSARLANDEPGLGAQAVYLDEHMNYPYGVTLVQIEIDPATGGHTLRRFLTST
HHHCCCCCCEEEECCCCCCCCEEEEEEHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHC
EAGRAINPMTTRGQVIGAAAQGIGGALYEEFLYDESGQPLATSFMDYLLPTSLDVPDVDF
CCCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCE
FMTEDAPTPNNPFGAKGLGEVGLIAVGAAIAGAIDDAFGEGVRTIKVPVPPETLWRRSHS
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCC
IAFSDEPESM
EEECCCCCCC
>Mature Secondary Structure 
SRPGASGGLGPSAKRYVGQPVRRREDARLLRGDARFVDDVDIHGQLYMSVVRSSEAHAR
CCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEE
IVSVEPSAARRAPGVRLVITADDIDAEVPLEQIGYHEVYPQIDDYLHPVFAGDRVRYVGQ
EEEECCHHHHCCCCEEEEEEECCCCCCCCHHHCCCHHHCCCHHHHHCHHHCCCEEEECCC
PVAAVIADTPYLAEDAAGLVEVTYDLLPPVLDPQYALTDEAEPLFEGQSNEAVRIVKAYG
CHHHHHCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEHHHH
DVADAFKKAAHVVKGRYVVGRHSGVPMETRGCIAEPDRGRKQLFMWGPVHTHDCQRLIAQ
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHH
VLELPLADLRMKHVDIGGNFGVKGGVFPEYIMVGWAAMRLGRPVKWTEDRLEHMVANAHA
HHHCCHHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
REQVHEMAAAFDADGVLLALKDEIWHNHGAFIRQAEPLVSDITVGMVPGPYRVPAYDGLL
HHHHHHHHHHCCCCCEEEEEEHHHHCCCCCHHECCCHHHHHCEEEECCCCCCCCCCCCEE
HVVVSNKTPLSAYRAPGRYEGTFARERLLDLAAEQIGISQVEIRRRNLLTEADLPFAPGM
EEEECCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCC
DICFEPYHFDSGDVVDHLDKALESAGFDDWEREAAELRAQGRLVGNGIGMLMDKAGLGLY
CCEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCHHHHHHHCCCCEE
ETSAIDVDASGRIRVRTGASSVGQGIETVLAQIVADELQVDPELIDVVHGDTELVPEGVG
ECCEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHCCCCCC
SWSSRSTVLAGGAARQAALDTLAKAKRLASEMLEANVDDLILVDGRIVVSGLEQQGLSLA
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEECHHHHCCHHH
EIAGRWDGWSARLANDEPGLGAQAVYLDEHMNYPYGVTLVQIEIDPATGGHTLRRFLTST
HHHCCCCCCEEEECCCCCCCCEEEEEEHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHC
EAGRAINPMTTRGQVIGAAAQGIGGALYEEFLYDESGQPLATSFMDYLLPTSLDVPDVDF
CCCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCE
FMTEDAPTPNNPFGAKGLGEVGLIAVGAAIAGAIDDAFGEGVRTIKVPVPPETLWRRSHS
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCC
IAFSDEPESM
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]