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The map label for this gene is trpB

Identifier: 119386498

GI number: 119386498

Start: 925618

End: 926850

Strand: Direct

Name: trpB

Synonym: Pden_3791

Alternate gene names: 119386498

Gene position: 925618-926850 (Clockwise)

Preceding gene: 119386497

Following gene: 119386500

Centisome position: 53.5

GC content: 66.99

Gene sequence:

>1233_bases
ATGGCCGAAGACCTCATCAACAGCTTCATGACCGGCCCGGACGAGCAGGGCCGCTTCGGCATCTTCGGCGGCCGCTTCGT
CAGCGAGACGCTGATGCCGCTGATCCTCGACCTCGAGGCCGAATACGAGCGCGCCAAGGACGACGCGTCCTTCTGGGCCG
AGATGGACGATCTGTGGAAACATTACGTCGGCCGGCCCAGCCCGCTCTATTTCGCCCCGCGCCTGACCGAGGAACTGGGC
GGTGCCAAGATCTATCTCAAGCGCGAAGAGCTGAACCATACCGGCAGCCACAAGATCAACAACGTGCTGGGCCAGATCCT
GCTGGCGCGCCGCATGGGCAAGACCCGGATCATCGCCGAAACCGGCGCCGGCCAGCATGGCGTGGCGACCGCGACGGTCT
GCGCCCGCTTCGGGCTGAAATGCATCGTCTACATGGGCGCGCATGACGTCGAGCGCCAGGCGCCGAACGTCTTCCGCATG
CGGCTGCTGGGCGCCGAGGTGGTGCCGGTCACCTCGGGCCGCGGCACGCTCAAGGATGCGATGAACGACGCGCTGCGCGA
CTGGGTGACCAATGTGCGCGACACCTTCTATTGCATCGGCACCGTCGCCGGCCCGCATCCCTATCCGGCCATGGTGCGCG
ATTTCCAATGCATCATCGGTCGCGAGACCCGCCGGCAACTGGCCGAGCAGGAAGGCGAGGGGCGGCTGCCCGACAGCGTG
GTCGCGGCCATCGGCGGCGGCTCGAACGCCATGGGGCTGTTCCATCCCTTCCTCGACGAGCCCTCGGTGCGCATCATCGG
CGTCGAGGCCGGCGGCAAGGGCGTCGACGAGCGCATGCAGCATTGCGCCAGCCTGACCGGCGGCCGCCCCGGCGTGCTGC
ACGGCAATCGCACCTATCTGCTCCAGGACGGCGAGGGCCAGATCCTCGAAGGCCATTCGATCAGCGCCGGTCTGGACTAT
CCCGGTATCGGACCCGAGCATGCCTGGCTCAAGGAACAGGGCCGCGCCGAATATGTCAGCGTGACCGATGACGAGGCGCT
GGCGGCCTTCCAGACCCTTTGCCGGCTCGAAGGCATCATCCCGGCGCTGGAGCCCAGCCACGCGCTGGCCCATGTCGTCA
AGATCGCGCCGGACCTGCCGCGCGACCATATCATGGTGGTGAACCTGTCGGGCCGGGGCGACAAGGACATCTTCACCGTC
GCCAAGCATCTCGGCGTCGATATCCGCACCTGA

Upstream 100 bases:

>100_bases
AGGCTCGGCTTTACCCCTTCCCATATCGGATATAAGAAATCCCTCTGACGGGGCTTCTCTGTTCCCCAAATACTCATTGC
GACCGCGCCCGAGGAGAGCC

Downstream 100 bases:

>100_bases
ATGCGAAAGGCGCGCGCTATTTCGCGGCGCGCGCCTCGGCCACCAGTTCGGCCAGGTCGTCCTTGCTCAGATAGCCGAAG
ATCGCCCGGTCGCCGGCGAT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MAEDLINSFMTGPDEQGRFGIFGGRFVSETLMPLILDLEAEYERAKDDASFWAEMDDLWKHYVGRPSPLYFAPRLTEELG
GAKIYLKREELNHTGSHKINNVLGQILLARRMGKTRIIAETGAGQHGVATATVCARFGLKCIVYMGAHDVERQAPNVFRM
RLLGAEVVPVTSGRGTLKDAMNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQCIIGRETRRQLAEQEGEGRLPDSV
VAAIGGGSNAMGLFHPFLDEPSVRIIGVEAGGKGVDERMQHCASLTGGRPGVLHGNRTYLLQDGEGQILEGHSISAGLDY
PGIGPEHAWLKEQGRAEYVSVTDDEALAAFQTLCRLEGIIPALEPSHALAHVVKIAPDLPRDHIMVVNLSGRGDKDIFTV
AKHLGVDIRT

Sequences:

>Translated_410_residues
MAEDLINSFMTGPDEQGRFGIFGGRFVSETLMPLILDLEAEYERAKDDASFWAEMDDLWKHYVGRPSPLYFAPRLTEELG
GAKIYLKREELNHTGSHKINNVLGQILLARRMGKTRIIAETGAGQHGVATATVCARFGLKCIVYMGAHDVERQAPNVFRM
RLLGAEVVPVTSGRGTLKDAMNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQCIIGRETRRQLAEQEGEGRLPDSV
VAAIGGGSNAMGLFHPFLDEPSVRIIGVEAGGKGVDERMQHCASLTGGRPGVLHGNRTYLLQDGEGQILEGHSISAGLDY
PGIGPEHAWLKEQGRAEYVSVTDDEALAAFQTLCRLEGIIPALEPSHALAHVVKIAPDLPRDHIMVVNLSGRGDKDIFTV
AKHLGVDIRT
>Mature_409_residues
AEDLINSFMTGPDEQGRFGIFGGRFVSETLMPLILDLEAEYERAKDDASFWAEMDDLWKHYVGRPSPLYFAPRLTEELGG
AKIYLKREELNHTGSHKINNVLGQILLARRMGKTRIIAETGAGQHGVATATVCARFGLKCIVYMGAHDVERQAPNVFRMR
LLGAEVVPVTSGRGTLKDAMNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQCIIGRETRRQLAEQEGEGRLPDSVV
AAIGGGSNAMGLFHPFLDEPSVRIIGVEAGGKGVDERMQHCASLTGGRPGVLHGNRTYLLQDGEGQILEGHSISAGLDYP
GIGPEHAWLKEQGRAEYVSVTDDEALAAFQTLCRLEGIIPALEPSHALAHVVKIAPDLPRDHIMVVNLSGRGDKDIFTVA
KHLGVDIRT

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=383, Percent_Identity=57.9634464751958, Blast_Score=442, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6321412, Length=404, Percent_Identity=54.7029702970297, Blast_Score=467, Evalue=1e-132,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_PARDP (A1B8L3)

Other databases:

- EMBL:   CP000490
- RefSeq:   YP_917553.1
- ProteinModelPortal:   A1B8L3
- SMR:   A1B8L3
- STRING:   A1B8L3
- GeneID:   4582342
- GenomeReviews:   CP000490_GR
- KEGG:   pde:Pden_3791
- eggNOG:   COG0133
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- PhylomeDB:   A1B8L3
- ProtClustDB:   PRK04346
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 44831; Mature: 44700

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEDLINSFMTGPDEQGRFGIFGGRFVSETLMPLILDLEAEYERAKDDASFWAEMDDLWK
CHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHH
HYVGRPSPLYFAPRLTEELGGAKIYLKREELNHTGSHKINNVLGQILLARRMGKTRIIAE
HHCCCCCCEEECCHHHHHCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
TGAGQHGVATATVCARFGLKCIVYMGAHDVERQAPNVFRMRLLGAEVVPVTSGRGTLKDA
CCCCCCCHHHHHHHHHHCCEEEEEECCCHHHHCCCHHHHHHHHCCEEEEECCCCCHHHHH
MNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQCIIGRETRRQLAEQEGEGRLPDSV
HHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHH
VAAIGGGSNAMGLFHPFLDEPSVRIIGVEAGGKGVDERMQHCASLTGGRPGVLHGNRTYL
HEEECCCCCCCHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEECCEEEE
LQDGEGQILEGHSISAGLDYPGIGPEHAWLKEQGRAEYVSVTDDEALAAFQTLCRLEGII
EECCCCCEEECCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCC
PALEPSHALAHVVKIAPDLPRDHIMVVNLSGRGDKDIFTVAKHLGVDIRT
CCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AEDLINSFMTGPDEQGRFGIFGGRFVSETLMPLILDLEAEYERAKDDASFWAEMDDLWK
HHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHH
HYVGRPSPLYFAPRLTEELGGAKIYLKREELNHTGSHKINNVLGQILLARRMGKTRIIAE
HHCCCCCCEEECCHHHHHCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
TGAGQHGVATATVCARFGLKCIVYMGAHDVERQAPNVFRMRLLGAEVVPVTSGRGTLKDA
CCCCCCCHHHHHHHHHHCCEEEEEECCCHHHHCCCHHHHHHHHCCEEEEECCCCCHHHHH
MNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQCIIGRETRRQLAEQEGEGRLPDSV
HHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHH
VAAIGGGSNAMGLFHPFLDEPSVRIIGVEAGGKGVDERMQHCASLTGGRPGVLHGNRTYL
HEEECCCCCCCHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEECCEEEE
LQDGEGQILEGHSISAGLDYPGIGPEHAWLKEQGRAEYVSVTDDEALAAFQTLCRLEGII
EECCCCCEEECCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCC
PALEPSHALAHVVKIAPDLPRDHIMVVNLSGRGDKDIFTVAKHLGVDIRT
CCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA