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The map label for this gene is tlyC [H]

Identifier: 119386402

GI number: 119386402

Start: 842608

End: 843540

Strand: Direct

Name: tlyC [H]

Synonym: Pden_3694

Alternate gene names: 119386402

Gene position: 842608-843540 (Clockwise)

Preceding gene: 119386401

Following gene: 119386406

Centisome position: 48.7

GC content: 69.13

Gene sequence:

>933_bases
ATGACCAACGACCGAAGTCCCGACACGCCCGTCTCCACCGAACCCGCCTCATGGGCGGATGGCACGGGCGGGGACGGGCG
TGACCTGCCGCAATCGCGCGGCTTTCTGGGGCGCATCCTGGGTGCCTTCGGCGGCGGCGGCGAGCCCGAGCCCGAGGGCG
CCGAGGCCCGCGACAAGGGACCGGCCGCCCCGTCGTCGGGCGTTCCCGGGATGGTCAACCTGCGGCGGATGCGCGTCGAC
GACGTGGCCGTGCCCAAGGCCGAGATCGTCGCCGCGCCGGTGACTGCCACCCTGCCGGAACTGGTCGAGATGTTCCGCGA
GCACGGCTTTTCCCGCATCCCGGTGTTTCGTGGCACGCTGGACAGCCCGCTGGGGCTGATCCACCTGAAGGATCTGGCGC
TGAAATACGGCTTCGGCGTCAAGGCTCCGGTCAAGTTCGCGCTGCGCCCGATGCTGCGGCCGCTGCTTTACGTGCCGCCC
TCGATGCCCATCGGCGTGCTCTTGCAGCAGATGCAGCAAAAGCGCATCCACATGGCGCTGGTGATCGACGAATATGGCGG
CGTGGACGGGCTCGTCACCATCGAGGACCTGATCGAGCAGGTCATCGGCGAGATCGAGGACGAGCATGACGAGATCGAGG
GCGGGCTCGTCATCCAGGAAAAGCCCGGCCAATGGCTGATCCAGGCCCGCGCCGCGCTGGAGGATGTCGAGGCCCAGACC
GGCCTGCGCCTTGCCACCGACGAGGAAGAGGAAGAGATCGACACGCTGGGCGGCCTGATCTTCATGCTGACCGGCCGGGT
GCCGGTGCGCGGCGAGGTGATCCCGCATGAAAGCGGCGCCGAGTTCGAGATCGTCGACGCCGATCCGCGCCGGGTCAAGC
GCGTGCGGCTCCGGCTGCCGCAACAGGAGGCGCCGCCGGAGAGCGAGGGCTGA

Upstream 100 bases:

>100_bases
ATGACCATATCGACGACGAGGATGCCGAAACCATGGAGGATGCAGAACGCTCGATCCTGGGCAAGCTGGGCATCCCCGAC
CCTTATCTGGAACATGAGAC

Downstream 100 bases:

>100_bases
GGCGTGTCACAGCCCGGCAAAGGCCGGGGCATGGGCGATGCGGCTGCCTGCGGGCAGCTCAGGCCCCAGCGCCATGAGAT
GCGGCCCGGCATAGGGCGAA

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTNDRSPDTPVSTEPASWADGTGGDGRDLPQSRGFLGRILGAFGGGGEPEPEGAEARDKGPAAPSSGVPGMVNLRRMRVD
DVAVPKAEIVAAPVTATLPELVEMFREHGFSRIPVFRGTLDSPLGLIHLKDLALKYGFGVKAPVKFALRPMLRPLLYVPP
SMPIGVLLQQMQQKRIHMALVIDEYGGVDGLVTIEDLIEQVIGEIEDEHDEIEGGLVIQEKPGQWLIQARAALEDVEAQT
GLRLATDEEEEEIDTLGGLIFMLTGRVPVRGEVIPHESGAEFEIVDADPRRVKRVRLRLPQQEAPPESEG

Sequences:

>Translated_310_residues
MTNDRSPDTPVSTEPASWADGTGGDGRDLPQSRGFLGRILGAFGGGGEPEPEGAEARDKGPAAPSSGVPGMVNLRRMRVD
DVAVPKAEIVAAPVTATLPELVEMFREHGFSRIPVFRGTLDSPLGLIHLKDLALKYGFGVKAPVKFALRPMLRPLLYVPP
SMPIGVLLQQMQQKRIHMALVIDEYGGVDGLVTIEDLIEQVIGEIEDEHDEIEGGLVIQEKPGQWLIQARAALEDVEAQT
GLRLATDEEEEEIDTLGGLIFMLTGRVPVRGEVIPHESGAEFEIVDADPRRVKRVRLRLPQQEAPPESEG
>Mature_309_residues
TNDRSPDTPVSTEPASWADGTGGDGRDLPQSRGFLGRILGAFGGGGEPEPEGAEARDKGPAAPSSGVPGMVNLRRMRVDD
VAVPKAEIVAAPVTATLPELVEMFREHGFSRIPVFRGTLDSPLGLIHLKDLALKYGFGVKAPVKFALRPMLRPLLYVPPS
MPIGVLLQQMQQKRIHMALVIDEYGGVDGLVTIEDLIEQVIGEIEDEHDEIEGGLVIQEKPGQWLIQARAALEDVEAQTG
LRLATDEEEEEIDTLGGLIFMLTGRVPVRGEVIPHESGAEFEIVDADPRRVKRVRLRLPQQEAPPESEG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=181, Percent_Identity=32.0441988950276, Blast_Score=105, Evalue=7e-23,
Organism=Escherichia coli, GI1786879, Length=297, Percent_Identity=31.3131313131313, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI145693175, Length=247, Percent_Identity=22.2672064777328, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87082033, Length=229, Percent_Identity=27.0742358078603, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788119, Length=263, Percent_Identity=28.1368821292776, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33635; Mature: 33504

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDRSPDTPVSTEPASWADGTGGDGRDLPQSRGFLGRILGAFGGGGEPEPEGAEARDKG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PAAPSSGVPGMVNLRRMRVDDVAVPKAEIVAAPVTATLPELVEMFREHGFSRIPVFRGTL
CCCCCCCCCCCHHHHHEECCHHCCCHHHHEECCHHHHHHHHHHHHHHCCCCCCCEECCCC
DSPLGLIHLKDLALKYGFGVKAPVKFALRPMLRPLLYVPPSMPIGVLLQQMQQKRIHMAL
CCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHEEEEE
VIDEYGGVDGLVTIEDLIEQVIGEIEDEHDEIEGGLVIQEKPGQWLIQARAALEDVEAQT
EEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHC
GLRLATDEEEEEIDTLGGLIFMLTGRVPVRGEVIPHESGAEFEIVDADPRRVKRVRLRLP
CCEECCCCHHHHHHHHHHHHHEEECCCCCCCEECCCCCCCCEEEECCCHHHHHHHHHCCC
QQEAPPESEG
CCCCCCCCCC
>Mature Secondary Structure 
TNDRSPDTPVSTEPASWADGTGGDGRDLPQSRGFLGRILGAFGGGGEPEPEGAEARDKG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PAAPSSGVPGMVNLRRMRVDDVAVPKAEIVAAPVTATLPELVEMFREHGFSRIPVFRGTL
CCCCCCCCCCCHHHHHEECCHHCCCHHHHEECCHHHHHHHHHHHHHHCCCCCCCEECCCC
DSPLGLIHLKDLALKYGFGVKAPVKFALRPMLRPLLYVPPSMPIGVLLQQMQQKRIHMAL
CCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHEEEEE
VIDEYGGVDGLVTIEDLIEQVIGEIEDEHDEIEGGLVIQEKPGQWLIQARAALEDVEAQT
EEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHC
GLRLATDEEEEEIDTLGGLIFMLTGRVPVRGEVIPHESGAEFEIVDADPRRVKRVRLRLP
CCEECCCCHHHHHHHHHHHHHEEECCCCCCCEECCCCCCCCEEEECCCHHHHHHHHHCCC
QQEAPPESEG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA