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The map label for this gene is fepG [H]

Identifier: 119386245

GI number: 119386245

Start: 683546

End: 684598

Strand: Direct

Name: fepG [H]

Synonym: Pden_3534

Alternate gene names: 119386245

Gene position: 683546-684598 (Clockwise)

Preceding gene: 119386244

Following gene: 119386248

Centisome position: 39.51

GC content: 71.23

Gene sequence:

>1053_bases
ATGATTCTGCCCCGGACCCGTGCCCTTCGCATCGGCGGCGCCTCGGTCCTGTGGCGCCCGCGCAGCGTGACCGTCTGCCT
GGCGCTGTGCCTGCTGTGCCTTGTGCTGGCACTGCTGCTGTTGGGCACCGGCACGGCCCGGCTGTCGCCCGGACAGGTGG
TCGAGGGGCTGATCGGCTCATCGGACGATGCCACCGCAACGCGCGTGCTGCGCCGCATCCGGCTGCCGCGGGTGCTGACG
GCGGCGATGGTCGGGGCCTCTCTGGGCATGGCGGGGGCGGTCTTTCAGTCGCTGTCGCGCAATCCGCTTGGCTCGCCCGA
CGTGATCGGCTTCACCACCGGGGCCGCGACGGGGGCCATCGTGCAGATCACCCTGTTCAATGCCGGGACGTTCCAGGTCG
CATCGGCGGCGGTGATCTCGGGCCTGGCGACGGCGCTGGTCGTGCTGATGCTGTCGCGGCGCAAGGGGACCGAGGGCGGC
TATCGCCTGATCCTGGTCGGCATCGGCGTCGGTGCGGTGCTGACCGGGGTGAACAACGTGCTGATGGTCATGGGCAGCCT
CGAGCGCGCGATGTCGGCGCAGATCTGGCTGGCCGGCTCGTTGAACGCGCGAAGCTGGGGTCATGTCTGGCCGGCACTGG
CGGGGCTGGTGCTGTTTGCGCCGCTGGTTCTGCGGAACGCGCGCCGCCTCGCGTTGCTGGAGATGGGCGAGGCCCTGGCC
GCGCAGCTTGGGCTGAATGTCGGCCGGACCCGGGTGACGCTGGTGATCGTGGCCATCGGGCTGACCTCGGTCGCGACCGC
CAGCGCCGGTCCCATCGCCTTCGTCGCGCTGGCCGGGCCGCAGATCGCGCGTCGCCTGACCCGCTCGCCCGAACTGCCGC
TGCTGTCCGGGGCGTTGACGGGGGCGGCGCTGCTGATGGCGGCCGATCTGATCGGGCAATGGGCACCCTTCGGCCTGCTG
ATGCCCATCGGCACGATGACCGGGTTGTGCGGCGGGCTGTATCTGGTCTGGCTGCTGGGGCAGGGCGAAAGGACTGCCCC
GGCAGGCAGGTGA

Upstream 100 bases:

>100_bases
TCGTCGCGCCCCCGAACGAGATCGCGGCCGGCATCGTCGCGACGATCCTGGGTGGCCCGTTCTTCATCCATGTCGTGCGC
CGCTTCAGGCTGGCACGGCT

Downstream 100 bases:

>100_bases
GGCTGCGAAGGCGGTCGGCAAGATCGCCGGATCGCGGGCCCCGCCTTTGGCATGGGGCCCGCGATCCGGAATGTGCTTCA
GGCCGCGGGCACCGATGCGG

Product: transport system permease protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MILPRTRALRIGGASVLWRPRSVTVCLALCLLCLVLALLLLGTGTARLSPGQVVEGLIGSSDDATATRVLRRIRLPRVLT
AAMVGASLGMAGAVFQSLSRNPLGSPDVIGFTTGAATGAIVQITLFNAGTFQVASAAVISGLATALVVLMLSRRKGTEGG
YRLILVGIGVGAVLTGVNNVLMVMGSLERAMSAQIWLAGSLNARSWGHVWPALAGLVLFAPLVLRNARRLALLEMGEALA
AQLGLNVGRTRVTLVIVAIGLTSVATASAGPIAFVALAGPQIARRLTRSPELPLLSGALTGAALLMAADLIGQWAPFGLL
MPIGTMTGLCGGLYLVWLLGQGERTAPAGR

Sequences:

>Translated_350_residues
MILPRTRALRIGGASVLWRPRSVTVCLALCLLCLVLALLLLGTGTARLSPGQVVEGLIGSSDDATATRVLRRIRLPRVLT
AAMVGASLGMAGAVFQSLSRNPLGSPDVIGFTTGAATGAIVQITLFNAGTFQVASAAVISGLATALVVLMLSRRKGTEGG
YRLILVGIGVGAVLTGVNNVLMVMGSLERAMSAQIWLAGSLNARSWGHVWPALAGLVLFAPLVLRNARRLALLEMGEALA
AQLGLNVGRTRVTLVIVAIGLTSVATASAGPIAFVALAGPQIARRLTRSPELPLLSGALTGAALLMAADLIGQWAPFGLL
MPIGTMTGLCGGLYLVWLLGQGERTAPAGR
>Mature_350_residues
MILPRTRALRIGGASVLWRPRSVTVCLALCLLCLVLALLLLGTGTARLSPGQVVEGLIGSSDDATATRVLRRIRLPRVLT
AAMVGASLGMAGAVFQSLSRNPLGSPDVIGFTTGAATGAIVQITLFNAGTFQVASAAVISGLATALVVLMLSRRKGTEGG
YRLILVGIGVGAVLTGVNNVLMVMGSLERAMSAQIWLAGSLNARSWGHVWPALAGLVLFAPLVLRNARRLALLEMGEALA
AQLGLNVGRTRVTLVIVAIGLTSVATASAGPIAFVALAGPQIARRLTRSPELPLLSGALTGAALLMAADLIGQWAPFGLL
MPIGTMTGLCGGLYLVWLLGQGERTAPAGR

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=326, Percent_Identity=43.2515337423313, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1790740, Length=273, Percent_Identity=35.8974358974359, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1786347, Length=272, Percent_Identity=29.7794117647059, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1790741, Length=279, Percent_Identity=31.5412186379928, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788004, Length=276, Percent_Identity=30.4347826086957, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786805, Length=246, Percent_Identity=32.520325203252, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35948; Mature: 35948

Theoretical pI: Translated: 12.20; Mature: 12.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILPRTRALRIGGASVLWRPRSVTVCLALCLLCLVLALLLLGTGTARLSPGQVVEGLIGS
CCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
SDDATATRVLRRIRLPRVLTAAMVGASLGMAGAVFQSLSRNPLGSPDVIGFTTGAATGAI
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEE
VQITLFNAGTFQVASAAVISGLATALVVLMLSRRKGTEGGYRLILVGIGVGAVLTGVNNV
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHH
LMVMGSLERAMSAQIWLAGSLNARSWGHVWPALAGLVLFAPLVLRNARRLALLEMGEALA
HHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AQLGLNVGRTRVTLVIVAIGLTSVATASAGPIAFVALAGPQIARRLTRSPELPLLSGALT
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHH
GAALLMAADLIGQWAPFGLLMPIGTMTGLCGGLYLVWLLGQGERTAPAGR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MILPRTRALRIGGASVLWRPRSVTVCLALCLLCLVLALLLLGTGTARLSPGQVVEGLIGS
CCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
SDDATATRVLRRIRLPRVLTAAMVGASLGMAGAVFQSLSRNPLGSPDVIGFTTGAATGAI
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEE
VQITLFNAGTFQVASAAVISGLATALVVLMLSRRKGTEGGYRLILVGIGVGAVLTGVNNV
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHH
LMVMGSLERAMSAQIWLAGSLNARSWGHVWPALAGLVLFAPLVLRNARRLALLEMGEALA
HHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AQLGLNVGRTRVTLVIVAIGLTSVATASAGPIAFVALAGPQIARRLTRSPELPLLSGALT
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHH
GAALLMAADLIGQWAPFGLLMPIGTMTGLCGGLYLVWLLGQGERTAPAGR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 9278503 [H]