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The map label for this gene is yybE [H]

Identifier: 119386178

GI number: 119386178

Start: 610387

End: 611307

Strand: Direct

Name: yybE [H]

Synonym: Pden_3466

Alternate gene names: 119386178

Gene position: 610387-611307 (Clockwise)

Preceding gene: 119386175

Following gene: 119386181

Centisome position: 35.28

GC content: 68.51

Gene sequence:

>921_bases
ATGGTTCGCTTCACGCTGCGCCAATGCGCCTATTTCCGCGCCGTCGCCGAGCATGGCGGCATTGCGCAGGCCGCGCGCGC
GCTGAACATCTCTCAGCCCTCGGTGGCGCAGGCGCTGGAAAAGCTCGAGGACGTGACCCGTCTGGTGCTGTTCGAGCGGC
ATCATGCGCGCGGGCTGACGCTGACGCTGCAGGGCCGGCTGTTCCTTGAGCATGTGAACCGCCTCGAGGAACAGGCCGGG
CAGGTCGAGCGCGAGGCGGCGGCACTGGCGGCCGAGACCGCCGGAGAGATCCGGCTGGGCGTGTTCCGAACGCTGTCGCC
CTTTTACGCCGCGGGGCTGATCCGCAGTTTCGGCGAGGCGGTGCCGGGGGTGATCGTGCGGCAGCGCGAGATGGCGCTGG
CCAATCTGGCCGATGCGCTGCGCGACGGCTCGATCGACCTGGCACTGACCTATGATCGGGGCAGCGATCCCCAGGGGCTG
GCCTTCGTGCAGCTTGCGGCATTGCGACCGATGGTGGTTCTTGCCGCCGATCACCCGCTTGCCGGGCGCGATTCCATCGA
CCTCGCCGATCTGGCCGACGAGCCCTATGTCATGCTGGAAGGGCCCGGAAGCCGCAGCTATTTCGAGGAGCTTCTGGCCG
AAAGCGGGATCAGCCCGCCGGTCTCCTACGTCTCGACCTCGCTGGAGGCGGTGCGCAGTGCGGTCGCGGCGGGTTTCGGC
TTTACGCTGCTGGTGATGCGGCCCCCGTCGTCGATGACCTATGACGGGGGCGAGGTCAGGACCTTGCCGATCACGAACGA
CCTGCGCCCGCTGCGCATCGTGCTGGCCTCGCGCGATGGCGCGCATCGGGGACTTGTCGCGCGGCGCTTCACCCAGCATG
CCATTGGCTATTTCGCCGCCCGCCATCACGCCCCGGCCTGA

Upstream 100 bases:

>100_bases
GCGGACAGCCTGTTCGCGCGGGCCGCTGGTCGGGAACCAGCTTGACCTTTTTGCAAGGAATATGAAAACTTGAATATCCG
ATGATTAAGACAGGCAAAAT

Downstream 100 bases:

>100_bases
CGGCCTCGGAATGCCGGGACGCCGGGGACCGCGCCGTTCGGCAGAGTGGGGCGGGGCAGGGCGCCGAATGCGCGCCGACA
ACTCGCAAGCCGCATGGGCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MVRFTLRQCAYFRAVAEHGGIAQAARALNISQPSVAQALEKLEDVTRLVLFERHHARGLTLTLQGRLFLEHVNRLEEQAG
QVEREAAALAAETAGEIRLGVFRTLSPFYAAGLIRSFGEAVPGVIVRQREMALANLADALRDGSIDLALTYDRGSDPQGL
AFVQLAALRPMVVLAADHPLAGRDSIDLADLADEPYVMLEGPGSRSYFEELLAESGISPPVSYVSTSLEAVRSAVAAGFG
FTLLVMRPPSSMTYDGGEVRTLPITNDLRPLRIVLASRDGAHRGLVARRFTQHAIGYFAARHHAPA

Sequences:

>Translated_306_residues
MVRFTLRQCAYFRAVAEHGGIAQAARALNISQPSVAQALEKLEDVTRLVLFERHHARGLTLTLQGRLFLEHVNRLEEQAG
QVEREAAALAAETAGEIRLGVFRTLSPFYAAGLIRSFGEAVPGVIVRQREMALANLADALRDGSIDLALTYDRGSDPQGL
AFVQLAALRPMVVLAADHPLAGRDSIDLADLADEPYVMLEGPGSRSYFEELLAESGISPPVSYVSTSLEAVRSAVAAGFG
FTLLVMRPPSSMTYDGGEVRTLPITNDLRPLRIVLASRDGAHRGLVARRFTQHAIGYFAARHHAPA
>Mature_306_residues
MVRFTLRQCAYFRAVAEHGGIAQAARALNISQPSVAQALEKLEDVTRLVLFERHHARGLTLTLQGRLFLEHVNRLEEQAG
QVEREAAALAAETAGEIRLGVFRTLSPFYAAGLIRSFGEAVPGVIVRQREMALANLADALRDGSIDLALTYDRGSDPQGL
AFVQLAALRPMVVLAADHPLAGRDSIDLADLADEPYVMLEGPGSRSYFEELLAESGISPPVSYVSTSLEAVRSAVAAGFG
FTLLVMRPPSSMTYDGGEVRTLPITNDLRPLRIVLASRDGAHRGLVARRFTQHAIGYFAARHHAPA

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=294, Percent_Identity=26.1904761904762, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790399, Length=252, Percent_Identity=30.5555555555556, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787601, Length=295, Percent_Identity=28.135593220339, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787879, Length=300, Percent_Identity=27.6666666666667, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789204, Length=282, Percent_Identity=30.1418439716312, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787530, Length=237, Percent_Identity=22.3628691983122, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081904, Length=257, Percent_Identity=26.4591439688716, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367136, Length=243, Percent_Identity=27.9835390946502, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789506, Length=264, Percent_Identity=26.1363636363636, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788887, Length=285, Percent_Identity=24.2105263157895, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=24.1803278688525, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI145693105, Length=236, Percent_Identity=24.5762711864407, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33150; Mature: 33150

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRFTLRQCAYFRAVAEHGGIAQAARALNISQPSVAQALEKLEDVTRLVLFERHHARGLT
CCEEHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
LTLQGRLFLEHVNRLEEQAGQVEREAAALAAETAGEIRLGVFRTLSPFYAAGLIRSFGEA
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHH
VPGVIVRQREMALANLADALRDGSIDLALTYDRGSDPQGLAFVQLAALRPMVVLAADHPL
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCEEEEEECCCC
AGRDSIDLADLADEPYVMLEGPGSRSYFEELLAESGISPPVSYVSTSLEAVRSAVAAGFG
CCCCCCCHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
FTLLVMRPPSSMTYDGGEVRTLPITNDLRPLRIVLASRDGAHRGLVARRFTQHAIGYFAA
EEEEEECCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
RHHAPA
HCCCCC
>Mature Secondary Structure
MVRFTLRQCAYFRAVAEHGGIAQAARALNISQPSVAQALEKLEDVTRLVLFERHHARGLT
CCEEHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
LTLQGRLFLEHVNRLEEQAGQVEREAAALAAETAGEIRLGVFRTLSPFYAAGLIRSFGEA
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHH
VPGVIVRQREMALANLADALRDGSIDLALTYDRGSDPQGLAFVQLAALRPMVVLAADHPL
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCEEEEEECCCC
AGRDSIDLADLADEPYVMLEGPGSRSYFEELLAESGISPPVSYVSTSLEAVRSAVAAGFG
CCCCCCCHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
FTLLVMRPPSSMTYDGGEVRTLPITNDLRPLRIVLASRDGAHRGLVARRFTQHAIGYFAA
EEEEEECCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
RHHAPA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]