Click here to switch to the map view.

The map label for this gene is tolC [C]

Identifier: 119357466

GI number: 119357466

Start: 1892412

End: 1893806

Strand: Direct

Name: tolC [C]

Synonym: Cpha266_1665

Alternate gene names: 119357466

Gene position: 1892412-1893806 (Clockwise)

Preceding gene: 119357465

Following gene: 119357467

Centisome position: 60.39

GC content: 46.09

Gene sequence:

>1395_bases
TTGACCATCAGGCTTGTTTTCATTTTCTGTATTGCATCGCTCCTTTTTTTCACCCCGTCAGAAAGCAATGCGCTTGAACC
CGTAGATAAAAAAGTATCACTTGACGAGTGTATCGCAATAGCCCTTGAAAATGCATCAACAACAAAAAAAGCAGAGAACT
CTCTCAGGCTTCAGGGAGCTGACATCCTGAGAAGTTATGGTAATTTTCTTCCGAAAATCTCGGCATCGGCAAGTTATATA
CCATACAGCCTCAGCCGATCTTACACGGATCTCACAGGATCAGCAAATCAAACCAAAAAGATCAAAACAAAAAGTGAAAC
CATTGATCTCACCCTTACAACATCACTGAATATTTTTAATGGATTCAGGGATTACGCATCACTGCAAGCCGCACTGAAAA
GAGAAGATGCGGGACGATTTTCCCTGTCGAGAGCTAAACAGGCGATAGTTTTCGATGTCACCCAGGCATACTACCAGGTT
CTCCTGAATCAGGAAATTCTTGCCATTACGCGTGAAAATCTGCTCTCGACAAAAGACCAGCTAACCCTCACCGACAGGCA
ATTTCAGATCGGCCTGAAATCAATGATTGATCTCTATCAGCAGCAGGCAGAAGCGGCCAACAGCGAGTTATCGGTTATCC
AGGCCGAAAACCAGCTTGAACGGAGCAGACTCGAACTGTTGCGCCGTCTGCGGATTGATCCACTCACCAGACTTACGCTT
GCACCTGTACCAAAGAACCTCTTCACAACGCTTCCTGAAAACATCGACATCAACGCACTTATTGCAGCAGGCCTTGAAAA
ACGCCCGGATCTCAAAGGCGCGGAACTCGAAACCCGAGCGGCAAAATGGCAGATAACCCAGTACCGGGGAGCTCTCTATC
CAAAATTCGACCTGAATTTCAACATCAGTACAAGCGGAACAGAATCCCTTAGCCGATCAATAGGTGGAGATACTATTGAC
TACTCCTATCCGCCCCTTCTTGATCAGCTTGAAAATCTGACCGGATACTCTGTGGTACTCAGCATGAACTGGGCAATTTT
TGACGGCTTTCAAACCCGGTATGCTATCGAGCAGGCCAAAATCAATTACCTTAACCAGAGGCTTGACTATGACGATCTGA
AATCGGATATCCAGATCGAACTTCAGCAGGCCGCCTCTGAATATTCGGCAGCACGAAAAAGCATTGAATCAGCCAAAACA
AACCTGAAAGCTGCGCGTGCTGCATATGAAGGTATAAAAAGAAAGTATGATCTTGGGGCAGCGGGATTCGTTGAATTGAG
CACCTCAAGAGCAGCTCTTTTCAGCGCCATGTCAAGCCTGAGCCAGGCCACCTACACCCTTGCTCTTCAGAAAAACACAC
TTGATTTTGCTACAGGAAACGTACCTATTTATTGA

Upstream 100 bases:

>100_bases
ATGATCTACCTGATCAGCGGGAAGCTTAATTTTGGCTTACCCACTTGAAATAGCGAGGAGCCAAAGATTTTCATCAACCA
AACGGTATACAGTTTCACTT

Downstream 100 bases:

>100_bases
ACAACGCAAATTTTTTGCAAGAACCAATGTCAAAAAAGAAACCTTCACAGAAACGCAACACGATAATCTTTGCTCTAACC
GGAATTCTTGTTGCTGGCGG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: LC Family Type I Secretion Outer Membrane Protein; Outer Membrane Transport/Efflux Protein; Type I Secretion Outer Membrane Protein lC Family; Outer Membrane Protein; HlyD Family Secretion Protein; RND Efflux System Outer Membrane Lipoprotein NodT; Type I Secretion Outer Membrane Protein lC; Type I Secretion Outer Membrane Protein; Outer Membrane Channel Protein; Outer Membrane Macrolide Efflux Protein; LC Protein; Outer lC Membrane Protein; FusA/NodT Family Protein; Outer Membrane Protein-Like Protein; Outer Membrane Efflux Protein RaxC; Outer Membrane Efflux Family Protein; LC Outer Membrane Protein; Outer Membrane Export Factor

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTIRLVFIFCIASLLFFTPSESNALEPVDKKVSLDECIAIALENASTTKKAENSLRLQGADILRSYGNFLPKISASASYI
PYSLSRSYTDLTGSANQTKKIKTKSETIDLTLTTSLNIFNGFRDYASLQAALKREDAGRFSLSRAKQAIVFDVTQAYYQV
LLNQEILAITRENLLSTKDQLTLTDRQFQIGLKSMIDLYQQQAEAANSELSVIQAENQLERSRLELLRRLRIDPLTRLTL
APVPKNLFTTLPENIDINALIAAGLEKRPDLKGAELETRAAKWQITQYRGALYPKFDLNFNISTSGTESLSRSIGGDTID
YSYPPLLDQLENLTGYSVVLSMNWAIFDGFQTRYAIEQAKINYLNQRLDYDDLKSDIQIELQQAASEYSAARKSIESAKT
NLKAARAAYEGIKRKYDLGAAGFVELSTSRAALFSAMSSLSQATYTLALQKNTLDFATGNVPIY

Sequences:

>Translated_464_residues
MTIRLVFIFCIASLLFFTPSESNALEPVDKKVSLDECIAIALENASTTKKAENSLRLQGADILRSYGNFLPKISASASYI
PYSLSRSYTDLTGSANQTKKIKTKSETIDLTLTTSLNIFNGFRDYASLQAALKREDAGRFSLSRAKQAIVFDVTQAYYQV
LLNQEILAITRENLLSTKDQLTLTDRQFQIGLKSMIDLYQQQAEAANSELSVIQAENQLERSRLELLRRLRIDPLTRLTL
APVPKNLFTTLPENIDINALIAAGLEKRPDLKGAELETRAAKWQITQYRGALYPKFDLNFNISTSGTESLSRSIGGDTID
YSYPPLLDQLENLTGYSVVLSMNWAIFDGFQTRYAIEQAKINYLNQRLDYDDLKSDIQIELQQAASEYSAARKSIESAKT
NLKAARAAYEGIKRKYDLGAAGFVELSTSRAALFSAMSSLSQATYTLALQKNTLDFATGNVPIY
>Mature_463_residues
TIRLVFIFCIASLLFFTPSESNALEPVDKKVSLDECIAIALENASTTKKAENSLRLQGADILRSYGNFLPKISASASYIP
YSLSRSYTDLTGSANQTKKIKTKSETIDLTLTTSLNIFNGFRDYASLQAALKREDAGRFSLSRAKQAIVFDVTQAYYQVL
LNQEILAITRENLLSTKDQLTLTDRQFQIGLKSMIDLYQQQAEAANSELSVIQAENQLERSRLELLRRLRIDPLTRLTLA
PVPKNLFTTLPENIDINALIAAGLEKRPDLKGAELETRAAKWQITQYRGALYPKFDLNFNISTSGTESLSRSIGGDTIDY
SYPPLLDQLENLTGYSVVLSMNWAIFDGFQTRYAIEQAKINYLNQRLDYDDLKSDIQIELQQAASEYSAARKSIESAKTN
LKAARAAYEGIKRKYDLGAAGFVELSTSRAALFSAMSSLSQATYTLALQKNTLDFATGNVPIY

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082199, Length=394, Percent_Identity=21.8274111675127, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51746; Mature: 51615

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRLVFIFCIASLLFFTPSESNALEPVDKKVSLDECIAIALENASTTKKAENSLRLQGA
CEEEHHHHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHHHHCCCCCCHHHHHCCEEECHH
DILRSYGNFLPKISASASYIPYSLSRSYTDLTGSANQTKKIKTKSETIDLTLTTSLNIFN
HHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEECCCEEEEEEEECCHHHH
GFRDYASLQAALKREDAGRFSLSRAKQAIVFDVTQAYYQVLLNQEILAITRENLLSTKDQ
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
LTLTDRQFQIGLKSMIDLYQQQAEAANSELSVIQAENQLERSRLELLRRLRIDPLTRLTL
EEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCEEEE
APVPKNLFTTLPENIDINALIAAGLEKRPDLKGAELETRAAKWQITQYRGALYPKFDLNF
CCCCHHHHHHCCCCCCCHHHEECCCCCCCCCCCCCCHHHHHHEEEEHHCCCCCEEEECCE
NISTSGTESLSRSIGGDTIDYSYPPLLDQLENLTGYSVVLSMNWAIFDGFQTRYAIEQAK
EECCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCEECCCHHHHHHHHHH
INYLNQRLDYDDLKSDIQIELQQAASEYSAARKSIESAKTNLKAARAAYEGIKRKYDLGA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGFVELSTSRAALFSAMSSLSQATYTLALQKNTLDFATGNVPIY
CCEEEECCHHHHHHHHHHHHHHCEEEEEEECCCCEEECCCCCCC
>Mature Secondary Structure 
TIRLVFIFCIASLLFFTPSESNALEPVDKKVSLDECIAIALENASTTKKAENSLRLQGA
EEEHHHHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHHHHCCCCCCHHHHHCCEEECHH
DILRSYGNFLPKISASASYIPYSLSRSYTDLTGSANQTKKIKTKSETIDLTLTTSLNIFN
HHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEECCCEEEEEEEECCHHHH
GFRDYASLQAALKREDAGRFSLSRAKQAIVFDVTQAYYQVLLNQEILAITRENLLSTKDQ
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
LTLTDRQFQIGLKSMIDLYQQQAEAANSELSVIQAENQLERSRLELLRRLRIDPLTRLTL
EEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCEEEE
APVPKNLFTTLPENIDINALIAAGLEKRPDLKGAELETRAAKWQITQYRGALYPKFDLNF
CCCCHHHHHHCCCCCCCHHHEECCCCCCCCCCCCCCHHHHHHEEEEHHCCCCCEEEECCE
NISTSGTESLSRSIGGDTIDYSYPPLLDQLENLTGYSVVLSMNWAIFDGFQTRYAIEQAK
EECCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCEECCCHHHHHHHHHH
INYLNQRLDYDDLKSDIQIELQQAASEYSAARKSIESAKTNLKAARAAYEGIKRKYDLGA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGFVELSTSRAALFSAMSSLSQATYTLALQKNTLDFATGNVPIY
CCEEEECCHHHHHHHHHHHHHHCEEEEEEECCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA