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The map label for this gene is arpC [H]

Identifier: 119357057

GI number: 119357057

Start: 1410851

End: 1412287

Strand: Direct

Name: arpC [H]

Synonym: Cpha266_1244

Alternate gene names: 119357057

Gene position: 1410851-1412287 (Clockwise)

Preceding gene: 119357056

Following gene: 119357059

Centisome position: 45.02

GC content: 53.03

Gene sequence:

>1437_bases
ATGAGAAATACAGACTTGGCGTTACTCTCTTTTGCCCTTCTCTTATCAGGCTGCAGTGCGGGTCCGGATTTTGTTCGACC
TGAAGCGCCGAAGAGCACCCGCTACACGTCAACTGAGGTTGCGTCTCGCATTGATGCGGAACATATCGGAAGGGAAGAGG
CGCAGATCGTTGTTCAAGGTGAGGTTTCAGACTCATGGTGGGAGGCATTCAACGCTCCAAAACTCAATGGGCTGATAGCG
GAAGCATTAATAAAAAATCCGACTCTTGAGTCCGCGGCAGCTATGCTTCGCCAGGCTGAATATCTCTATAAAGCTAAAGG
CGGATCGACCCTCTATCCACGGATCGATGCGGTTTCCGGCGCCCGGAGAGAGGGTATAAACGGGAGTATGACGGGGCAGG
AAGGCAGTCAAAAAACCTTTAATCTTTTCAACGCTTCTCTTGTTGCCGGTTACACGTTTGATCTTTCCGGAGGAAACCGT
CGGCAGCTGGAATCTCTTGCGGCAAAGGCCGGTTATCAGCGTTTTCAACTTGCAGGCGCACGATTGATGCTTGCCGCCGA
TATAGCATCAACAGCAATTCGTCAGGCAGAGCTTTCCGGCCAAATTGCGGCGATGGAAAAAATACTGGCCGCACGTCGCC
AGCAGCTTCAGATAACCCGCGAACGTCAGCGCCTCGGAGCTTCGTCGGGAGCAGAAGTTTTTGCCATGCAGGCCGTTGCG
GAGCAAGCCCGGGCGGTTTTGCCCGGCTTGCGTCAACAACTTGCCGAAACAAGACATCTGCTTGCCATTTTTGCAGGTCA
ATCGCCGGATAGAGGAGAAATACCCTCGTTTCTGTTACAGGATTTTACGCTGCCTCGCACGCTGCCGCTCAGGGTGCCAT
CATCTCTTGTTCGAGTGCGACCTGATATTCAGGCATCCGAAGCCCTTATGAAAGCGGCAAATGCCGATTATGGTGCAGCC
ATAGCGAAATCATTCCCTCAGATAACCCTGGGGGTCGATATCGGATCAACTGCGTTGACCCTGGCATCACTTTTCGGAGG
AGGATCGCTGGTTTGGGGAGTTGCCGGGCAGCTTGTTCAGCCGCTTTTCAACAGGGGGACAGGCGCAGAGCAAGATGCCG
CCAAAGCGGGATTTGATGCGGCCGCAGCAAACTATCGCCAGAGTGTGCTCAAGGGATTAAAGGAAGTTGCAGATGTTCTG
ACGGCTCTTGAAAACGATGCCCAAACCCTCTCTGCCTGCAGAGACGCCGATGAGGCAATACAGGCAGAGTTGCGCATCAT
GGAAAGTCGTTACAGGCTGGGGAGTGCATCTTTTCTTGAGATGTTACAGGCTCAAGATGAAGCGGAGCAGTATCGCATTG
AGCTCATCAAGGCAGAGTCGCGTCGCTTGTCGGATACGGTGGCTTTTTATCAGGCTATGGGAGGAAGCGGAAAATAA

Upstream 100 bases:

>100_bases
TACCTACCTTTAAGCGGATCTATCAAATTCGCGATGGTCGCACTCATGAAGAGGTTGGTGAGGGAAAATCTCCTTCGGAA
CAGCTTAAAACCTATTTGGA

Downstream 100 bases:

>100_bases
AAGGGCACCACCATGAAAGGCGCCTGCGTAATCGGGCAGGAAACTTTCGGACAAAGGGTGATGTCTCGCCGTTTGTCATG
AAATGACATGAGGATCCTTC

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MRNTDLALLSFALLLSGCSAGPDFVRPEAPKSTRYTSTEVASRIDAEHIGREEAQIVVQGEVSDSWWEAFNAPKLNGLIA
EALIKNPTLESAAAMLRQAEYLYKAKGGSTLYPRIDAVSGARREGINGSMTGQEGSQKTFNLFNASLVAGYTFDLSGGNR
RQLESLAAKAGYQRFQLAGARLMLAADIASTAIRQAELSGQIAAMEKILAARRQQLQITRERQRLGASSGAEVFAMQAVA
EQARAVLPGLRQQLAETRHLLAIFAGQSPDRGEIPSFLLQDFTLPRTLPLRVPSSLVRVRPDIQASEALMKAANADYGAA
IAKSFPQITLGVDIGSTALTLASLFGGGSLVWGVAGQLVQPLFNRGTGAEQDAAKAGFDAAAANYRQSVLKGLKEVADVL
TALENDAQTLSACRDADEAIQAELRIMESRYRLGSASFLEMLQAQDEAEQYRIELIKAESRRLSDTVAFYQAMGGSGK

Sequences:

>Translated_478_residues
MRNTDLALLSFALLLSGCSAGPDFVRPEAPKSTRYTSTEVASRIDAEHIGREEAQIVVQGEVSDSWWEAFNAPKLNGLIA
EALIKNPTLESAAAMLRQAEYLYKAKGGSTLYPRIDAVSGARREGINGSMTGQEGSQKTFNLFNASLVAGYTFDLSGGNR
RQLESLAAKAGYQRFQLAGARLMLAADIASTAIRQAELSGQIAAMEKILAARRQQLQITRERQRLGASSGAEVFAMQAVA
EQARAVLPGLRQQLAETRHLLAIFAGQSPDRGEIPSFLLQDFTLPRTLPLRVPSSLVRVRPDIQASEALMKAANADYGAA
IAKSFPQITLGVDIGSTALTLASLFGGGSLVWGVAGQLVQPLFNRGTGAEQDAAKAGFDAAAANYRQSVLKGLKEVADVL
TALENDAQTLSACRDADEAIQAELRIMESRYRLGSASFLEMLQAQDEAEQYRIELIKAESRRLSDTVAFYQAMGGSGK
>Mature_478_residues
MRNTDLALLSFALLLSGCSAGPDFVRPEAPKSTRYTSTEVASRIDAEHIGREEAQIVVQGEVSDSWWEAFNAPKLNGLIA
EALIKNPTLESAAAMLRQAEYLYKAKGGSTLYPRIDAVSGARREGINGSMTGQEGSQKTFNLFNASLVAGYTFDLSGGNR
RQLESLAAKAGYQRFQLAGARLMLAADIASTAIRQAELSGQIAAMEKILAARRQQLQITRERQRLGASSGAEVFAMQAVA
EQARAVLPGLRQQLAETRHLLAIFAGQSPDRGEIPSFLLQDFTLPRTLPLRVPSSLVRVRPDIQASEALMKAANADYGAA
IAKSFPQITLGVDIGSTALTLASLFGGGSLVWGVAGQLVQPLFNRGTGAEQDAAKAGFDAAAANYRQSVLKGLKEVADVL
TALENDAQTLSACRDADEAIQAELRIMESRYRLGSASFLEMLQAQDEAEQYRIELIKAESRRLSDTVAFYQAMGGSGK

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=487, Percent_Identity=28.1314168377823, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI2367348, Length=498, Percent_Identity=24.0963855421687, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 51339; Mature: 51339

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNTDLALLSFALLLSGCSAGPDFVRPEAPKSTRYTSTEVASRIDAEHIGREEAQIVVQG
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHCCCCCCEEEEEE
EVSDSWWEAFNAPKLNGLIAEALIKNPTLESAAAMLRQAEYLYKAKGGSTLYPRIDAVSG
CCCHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEECCCHHHHCC
ARREGINGSMTGQEGSQKTFNLFNASLVAGYTFDLSGGNRRQLESLAAKAGYQRFQLAGA
HHHCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCHHHHHHHCH
RLMLAADIASTAIRQAELSGQIAAMEKILAARRQQLQITRERQRLGASSGAEVFAMQAVA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
EQARAVLPGLRQQLAETRHLLAIFAGQSPDRGEIPSFLLQDFTLPRTLPLRVPSSLVRVR
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHCC
PDIQASEALMKAANADYGAAIAKSFPQITLGVDIGSTALTLASLFGGGSLVWGVAGQLVQ
CCCHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHH
PLFNRGTGAEQDAAKAGFDAAAANYRQSVLKGLKEVADVLTALENDAQTLSACRDADEAI
HHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHH
QAELRIMESRYRLGSASFLEMLQAQDEAEQYRIELIKAESRRLSDTVAFYQAMGGSGK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRNTDLALLSFALLLSGCSAGPDFVRPEAPKSTRYTSTEVASRIDAEHIGREEAQIVVQG
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHCCCCCCEEEEEE
EVSDSWWEAFNAPKLNGLIAEALIKNPTLESAAAMLRQAEYLYKAKGGSTLYPRIDAVSG
CCCHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEECCCHHHHCC
ARREGINGSMTGQEGSQKTFNLFNASLVAGYTFDLSGGNRRQLESLAAKAGYQRFQLAGA
HHHCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCHHHHHHHCH
RLMLAADIASTAIRQAELSGQIAAMEKILAARRQQLQITRERQRLGASSGAEVFAMQAVA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
EQARAVLPGLRQQLAETRHLLAIFAGQSPDRGEIPSFLLQDFTLPRTLPLRVPSSLVRVR
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHCC
PDIQASEALMKAANADYGAAIAKSFPQITLGVDIGSTALTLASLFGGGSLVWGVAGQLVQ
CCCHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHH
PLFNRGTGAEQDAAKAGFDAAAANYRQSVLKGLKEVADVLTALENDAQTLSACRDADEAI
HHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHH
QAELRIMESRYRLGSASFLEMLQAQDEAEQYRIELIKAESRRLSDTVAFYQAMGGSGK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]