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The map label for this gene is ynfJ [C]

Identifier: 119357059

GI number: 119357059

Start: 1413557

End: 1415419

Strand: Direct

Name: ynfJ [C]

Synonym: Cpha266_1246

Alternate gene names: 119357059

Gene position: 1413557-1415419 (Clockwise)

Preceding gene: 119357057

Following gene: 119357060

Centisome position: 45.11

GC content: 46.81

Gene sequence:

>1863_bases
ATGAAACTATCACCTAAAAAAAAGGGGAGTCTCAGCAGAAAGGGGCTGGCTTTTTTTTACAGTATTTCAAGGCGAAGCAG
GTATTTCAAAGGGACTTTTCAACAGTTTTTCAGGCTGACTTTAAAATATTTCCTTGTTCAACTGAATCTGAACCAGGATA
TTCCGTTTTTGTTTGTGGCTGTAGGAGTTGGCCTTCTTACCGGATATGTGGCTGTGGTGTTTCACGATGCTATTATGGTA
ATCAGTACCATCTGTTTTACAGGAATTCCTTCGTTGGCAAGTGCGCCTTTTTTTGAGAAGTACCGGATGATTATGCTTCC
ACTCATTCCCGCTTTCGGCGGTCTTCTTGTCGGTCTCTATAACGCGTTTGTGGTAAAGGAGCGTCCGGGACACGGGCTTG
CGTCAGTAATCAAGGCCGTTGCTCAGAATGATGGTGTTCTTAACCGTAAGCTCTGGATTCACAGAAGCATAACATCGGTA
TTAAGCATCGGTACAGGCGGCGGTGGTGGACGAGAAGCGCCGATTGTTCAGGTTGGCGCAGCAATTGGTTCAACTGTTGC
TCAGGTGCTGAAATTCTCGCCAAATAAAACCCGTACCCTCCTTGGTTGCGGGGCGGCTGCCGGGCTCGCCGCAGTTTTCA
ATACGCCTATCGGTGGCGTTATGTTTGCCATTGAGGTGCTGCTTGGAGATTTCAGCGTGAAGACCTTCAGTCCTATTGTG
ATTGCCGCCGTTATCGGCACCGTGCTTTCAAGAAGTTTTCTTGGCAATTCCCCGACATTTCAGGTTCATGAGTATACCCT
TGTTTCAAATACAGAGCTGGTTTTTTATTTTCTTCTCGGCATTCTTGCCGGTCTTTCGGCGGTTTTGTTTATCAGAATCT
ATTACGCCATAGAGGAGTGGTTCGAGAGAATTGAAAAACGGTGGAAAATTCCGGTATGGGCAATGCCTGCAATCGGCGGG
TTCATGGCCGGTCTGATCTGTTTATGGCTTCCCGGACTGTATGGGTTTTCCTATGAAGCTATTAACACGGCTCTGCTTGG
TAATGAAAGCTGGACCAACATGGTTGGTATCTATTTTCTCAAACCGGTTGTTGCAGCTCTATCGGTTGGTTCCGGCGGTT
CCGGAGGCATGTTTGCACCAGCCATGAAAATGGGCGCAATGCTTGGCGGTATGTTCGGCAATGCCGTCCATATGCTTTTC
CCTGAAATCACGGCAACGTCGGGAGCTTACGCCCTTGTCGGCATGGGCGCCCTGACAGCCGGGATCATGAGAGCCCCGCT
GTCGGTGATTCTCATTCTTTTTGAAATAACCGGCCAGTATGAAATCGTATTGCCCATCATGTTTGCCGCCGTAACATCAG
CTCTCATTGCCCGGCTTGTTTACCGTCACAGTATGGAAACCTACGTTCTTGAAAAAGAGGGGGTCAGAGTAGGATTTGGT
ATCGCGCTTTCAGTGGCCGAGCATATCAATATTTCAGATGTTATAAAAAAAAACTACATAAAATTTACAAACACCGTTCG
AGCAACAGTCATCATCGATACTTTTTACAATACGCCTGAATCATGTTTTTTGGTTACGGATAACAGGGGAAGATTTTCGG
GACTCATAAGGCTCGATGAGATGCGTATTCTGCTCAGGGAGGGATTGCCAGACGGGCTGATTGCGGAGGATGTGACAAAA
AAGGATGTTCCCGTTCTTTACAATACGTCTAAGCTTGATGAGGCGTTAAAGCTATTTGAAATAACGGATTATGATATGTT
GCCGGTTCTGGATGAAGAGACGGACATACTCCTCGGGGTTGTTCATCAGGAAGAGGCCTTTGCCTATTATCGCAAACAGC
TCAATCTTTACAGTTCTACATGA

Upstream 100 bases:

>100_bases
TTTGACAGATAGTCCGCTGCAAGTTTTTTCGTGAATATCAAGGTACGATGCATGAGGCACTCCGTTTCACACTTCCCCCC
CCATTTCTTTTAATTAATTC

Downstream 100 bases:

>100_bases
ACACGTGAGCGCAAAGAAAAGTACTTTTGTTCATCGTGCCCGGTGAACGTTATCCTTATGTGCTTTGTTTGATAAAGTGC
ATGAGGATGCCGGTATAAAG

Product: Cl- channel, voltage-gated family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MKLSPKKKGSLSRKGLAFFYSISRRSRYFKGTFQQFFRLTLKYFLVQLNLNQDIPFLFVAVGVGLLTGYVAVVFHDAIMV
ISTICFTGIPSLASAPFFEKYRMIMLPLIPAFGGLLVGLYNAFVVKERPGHGLASVIKAVAQNDGVLNRKLWIHRSITSV
LSIGTGGGGGREAPIVQVGAAIGSTVAQVLKFSPNKTRTLLGCGAAAGLAAVFNTPIGGVMFAIEVLLGDFSVKTFSPIV
IAAVIGTVLSRSFLGNSPTFQVHEYTLVSNTELVFYFLLGILAGLSAVLFIRIYYAIEEWFERIEKRWKIPVWAMPAIGG
FMAGLICLWLPGLYGFSYEAINTALLGNESWTNMVGIYFLKPVVAALSVGSGGSGGMFAPAMKMGAMLGGMFGNAVHMLF
PEITATSGAYALVGMGALTAGIMRAPLSVILILFEITGQYEIVLPIMFAAVTSALIARLVYRHSMETYVLEKEGVRVGFG
IALSVAEHINISDVIKKNYIKFTNTVRATVIIDTFYNTPESCFLVTDNRGRFSGLIRLDEMRILLREGLPDGLIAEDVTK
KDVPVLYNTSKLDEALKLFEITDYDMLPVLDEETDILLGVVHQEEAFAYYRKQLNLYSST

Sequences:

>Translated_620_residues
MKLSPKKKGSLSRKGLAFFYSISRRSRYFKGTFQQFFRLTLKYFLVQLNLNQDIPFLFVAVGVGLLTGYVAVVFHDAIMV
ISTICFTGIPSLASAPFFEKYRMIMLPLIPAFGGLLVGLYNAFVVKERPGHGLASVIKAVAQNDGVLNRKLWIHRSITSV
LSIGTGGGGGREAPIVQVGAAIGSTVAQVLKFSPNKTRTLLGCGAAAGLAAVFNTPIGGVMFAIEVLLGDFSVKTFSPIV
IAAVIGTVLSRSFLGNSPTFQVHEYTLVSNTELVFYFLLGILAGLSAVLFIRIYYAIEEWFERIEKRWKIPVWAMPAIGG
FMAGLICLWLPGLYGFSYEAINTALLGNESWTNMVGIYFLKPVVAALSVGSGGSGGMFAPAMKMGAMLGGMFGNAVHMLF
PEITATSGAYALVGMGALTAGIMRAPLSVILILFEITGQYEIVLPIMFAAVTSALIARLVYRHSMETYVLEKEGVRVGFG
IALSVAEHINISDVIKKNYIKFTNTVRATVIIDTFYNTPESCFLVTDNRGRFSGLIRLDEMRILLREGLPDGLIAEDVTK
KDVPVLYNTSKLDEALKLFEITDYDMLPVLDEETDILLGVVHQEEAFAYYRKQLNLYSST
>Mature_620_residues
MKLSPKKKGSLSRKGLAFFYSISRRSRYFKGTFQQFFRLTLKYFLVQLNLNQDIPFLFVAVGVGLLTGYVAVVFHDAIMV
ISTICFTGIPSLASAPFFEKYRMIMLPLIPAFGGLLVGLYNAFVVKERPGHGLASVIKAVAQNDGVLNRKLWIHRSITSV
LSIGTGGGGGREAPIVQVGAAIGSTVAQVLKFSPNKTRTLLGCGAAAGLAAVFNTPIGGVMFAIEVLLGDFSVKTFSPIV
IAAVIGTVLSRSFLGNSPTFQVHEYTLVSNTELVFYFLLGILAGLSAVLFIRIYYAIEEWFERIEKRWKIPVWAMPAIGG
FMAGLICLWLPGLYGFSYEAINTALLGNESWTNMVGIYFLKPVVAALSVGSGGSGGMFAPAMKMGAMLGGMFGNAVHMLF
PEITATSGAYALVGMGALTAGIMRAPLSVILILFEITGQYEIVLPIMFAAVTSALIARLVYRHSMETYVLEKEGVRVGFG
IALSVAEHINISDVIKKNYIKFTNTVRATVIIDTFYNTPESCFLVTDNRGRFSGLIRLDEMRILLREGLPDGLIAEDVTK
KDVPVLYNTSKLDEALKLFEITDYDMLPVLDEETDILLGVVHQEEAFAYYRKQLNLYSST

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557473, Length=384, Percent_Identity=28.3854166666667, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI189217923, Length=374, Percent_Identity=30.2139037433155, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI189217921, Length=374, Percent_Identity=30.2139037433155, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI153252026, Length=377, Percent_Identity=28.6472148541114, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI55770840, Length=448, Percent_Identity=26.3392857142857, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI55770838, Length=376, Percent_Identity=27.9255319148936, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI119433677, Length=392, Percent_Identity=23.2142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87081943, Length=421, Percent_Identity=27.0783847980998, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1786350, Length=307, Percent_Identity=31.2703583061889, Blast_Score=122, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17532615, Length=374, Percent_Identity=25.668449197861, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71980828, Length=421, Percent_Identity=24.2280285035629, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71980824, Length=421, Percent_Identity=24.2280285035629, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71980820, Length=426, Percent_Identity=23.943661971831, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 67717; Mature: 67717

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSPKKKGSLSRKGLAFFYSISRRSRYFKGTFQQFFRLTLKYFLVQLNLNQDIPFLFVA
CCCCCCCCCCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHH
VGVGLLTGYVAVVFHDAIMVISTICFTGIPSLASAPFFEKYRMIMLPLIPAFGGLLVGLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
NAFVVKERPGHGLASVIKAVAQNDGVLNRKLWIHRSITSVLSIGTGGGGGREAPIVQVGA
HHHEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHH
AIGSTVAQVLKFSPNKTRTLLGCGAAAGLAAVFNTPIGGVMFAIEVLLGDFSVKTFSPIV
HHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHH
IAAVIGTVLSRSFLGNSPTFQVHEYTLVSNTELVFYFLLGILAGLSAVLFIRIYYAIEEW
HHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FERIEKRWKIPVWAMPAIGGFMAGLICLWLPGLYGFSYEAINTALLGNESWTNMVGIYFL
HHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEECCCCHHHHHHHHHH
KPVVAALSVGSGGSGGMFAPAMKMGAMLGGMFGNAVHMLFPEITATSGAYALVGMGALTA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHH
GIMRAPLSVILILFEITGQYEIVLPIMFAAVTSALIARLVYRHSMETYVLEKEGVRVGFG
HHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCEEEEH
IALSVAEHINISDVIKKNYIKFTNTVRATVIIDTFYNTPESCFLVTDNRGRFSGLIRLDE
HHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEEECCCCCEEEEEEHHH
MRILLREGLPDGLIAEDVTKKDVPVLYNTSKLDEALKLFEITDYDMLPVLDEETDILLGV
HHHHHHCCCCCCCHHHCCCCCCCCEEECCHHHHHHHHHHEECCCCCCCCCCCCCCEEEEE
VHQEEAFAYYRKQLNLYSST
EEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLSPKKKGSLSRKGLAFFYSISRRSRYFKGTFQQFFRLTLKYFLVQLNLNQDIPFLFVA
CCCCCCCCCCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHH
VGVGLLTGYVAVVFHDAIMVISTICFTGIPSLASAPFFEKYRMIMLPLIPAFGGLLVGLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
NAFVVKERPGHGLASVIKAVAQNDGVLNRKLWIHRSITSVLSIGTGGGGGREAPIVQVGA
HHHEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHH
AIGSTVAQVLKFSPNKTRTLLGCGAAAGLAAVFNTPIGGVMFAIEVLLGDFSVKTFSPIV
HHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHH
IAAVIGTVLSRSFLGNSPTFQVHEYTLVSNTELVFYFLLGILAGLSAVLFIRIYYAIEEW
HHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FERIEKRWKIPVWAMPAIGGFMAGLICLWLPGLYGFSYEAINTALLGNESWTNMVGIYFL
HHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEECCCCHHHHHHHHHH
KPVVAALSVGSGGSGGMFAPAMKMGAMLGGMFGNAVHMLFPEITATSGAYALVGMGALTA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHH
GIMRAPLSVILILFEITGQYEIVLPIMFAAVTSALIARLVYRHSMETYVLEKEGVRVGFG
HHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCEEEEH
IALSVAEHINISDVIKKNYIKFTNTVRATVIIDTFYNTPESCFLVTDNRGRFSGLIRLDE
HHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEEECCCCCEEEEEEHHH
MRILLREGLPDGLIAEDVTKKDVPVLYNTSKLDEALKLFEITDYDMLPVLDEETDILLGV
HHHHHHCCCCCCCHHHCCCCCCCCEEECCHHHHHHHHHHEECCCCCCCCCCCCCCEEEEE
VHQEEAFAYYRKQLNLYSST
EEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]