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The map label for this gene is trxB [H]

Identifier: 119357013

GI number: 119357013

Start: 1357782

End: 1358717

Strand: Direct

Name: trxB [H]

Synonym: Cpha266_1197

Alternate gene names: 119357013

Gene position: 1357782-1358717 (Clockwise)

Preceding gene: 119357012

Following gene: 119357015

Centisome position: 43.33

GC content: 48.5

Gene sequence:

>936_bases
ATGGAACGCGACATCAGGGATATTGTTATCATGGGCACCGGTCCGGCCGGTTATACTGCAGCGATATACAGCGGCAGGGC
CAATCTCAAACCGCTTGTTATTGAAGGTTCGCAACCGGGCGGTCAGCTTATGATCACCAGCGAAATAGAGAATTTTCCCG
GATTTCCCGAAGGAATTTTCGGGCCGGAACTTATGGCAAGAATGCGTCAGCAGATTATTCGATTTGGCGTTGAGATTGCA
TATGGAAGCGTTCAGGATGTTGATCTTTCAAGAACGCCCTTCTCGCTTTCCCTCGATGACGGTACGGAAATCGTTACCCG
TTCACTTATTGTTGCCACCGGAGCGAATGCCAAATGGCTCAATATTGACTCCGAAAAAATGTATAGGGGCAAAGGCGTTT
CAGCCTGTGCGACCTGTGACGGTTTTTTCTTCAAGCAGTGCAAGGTGTTTGTTGTCGGCGGGGGAGATACAGCCATGGAA
GAGGCTTTATATCTCACCAAATTTGCAGCGGAGGTTATCATTGTTCACCGACGTGAAGAGTTCAGAGCATCGAAAATCAT
GAGTCTTCGAGCCGGTAAAAATCCGAAAATCAGCACCATGCTCAATCAGGTTGTTGATGAGATTCTCGGAGATGGTCACA
AAGTAACCGGAATACGACTTCAAAACGTGCTTACCGGTGAAAAGACGGAACATCAGTGCGATGGCGTGTTTATGGCTATC
GGTCACGCTCCTAATGCAGAGCTTTTCAAGGGTCAGCTTCGCATTGATGATTACGGTTATATCGAAACGAAAAAAACATC
GACTGAAACCAGCGTTCCCGGCGTTTTTGCCTGTGGTGACGTGCAGGATTACACCTATCGTCAAGCCATAACGGCAGCGG
GTACCGGCTGTATGGCCGCTGTCGATGCCGAGCGATTCCTTGAATCAATTCGTTAA

Upstream 100 bases:

>100_bases
AAACATCTGCATGATCGACTGATCCGGAAATCCGTTCTTGATAAGGGGATTTCCGGAAAGCTGTTCTGTGCCGGAACAAC
ATAATTTCCCCAAAAATATC

Downstream 100 bases:

>100_bases
TAAAGCCCGGAATCTGAACACACTCCTTCCGTGTCGGGCATGTCAGAGTCGTGGCAGGAGGAGGGGAGTTGCCCGTTAAC
ATCCAGTTCCGGATAGGGTA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MERDIRDIVIMGTGPAGYTAAIYSGRANLKPLVIEGSQPGGQLMITSEIENFPGFPEGIFGPELMARMRQQIIRFGVEIA
YGSVQDVDLSRTPFSLSLDDGTEIVTRSLIVATGANAKWLNIDSEKMYRGKGVSACATCDGFFFKQCKVFVVGGGDTAME
EALYLTKFAAEVIIVHRREEFRASKIMSLRAGKNPKISTMLNQVVDEILGDGHKVTGIRLQNVLTGEKTEHQCDGVFMAI
GHAPNAELFKGQLRIDDYGYIETKKTSTETSVPGVFACGDVQDYTYRQAITAAGTGCMAAVDAERFLESIR

Sequences:

>Translated_311_residues
MERDIRDIVIMGTGPAGYTAAIYSGRANLKPLVIEGSQPGGQLMITSEIENFPGFPEGIFGPELMARMRQQIIRFGVEIA
YGSVQDVDLSRTPFSLSLDDGTEIVTRSLIVATGANAKWLNIDSEKMYRGKGVSACATCDGFFFKQCKVFVVGGGDTAME
EALYLTKFAAEVIIVHRREEFRASKIMSLRAGKNPKISTMLNQVVDEILGDGHKVTGIRLQNVLTGEKTEHQCDGVFMAI
GHAPNAELFKGQLRIDDYGYIETKKTSTETSVPGVFACGDVQDYTYRQAITAAGTGCMAAVDAERFLESIR
>Mature_311_residues
MERDIRDIVIMGTGPAGYTAAIYSGRANLKPLVIEGSQPGGQLMITSEIENFPGFPEGIFGPELMARMRQQIIRFGVEIA
YGSVQDVDLSRTPFSLSLDDGTEIVTRSLIVATGANAKWLNIDSEKMYRGKGVSACATCDGFFFKQCKVFVVGGGDTAME
EALYLTKFAAEVIIVHRREEFRASKIMSLRAGKNPKISTMLNQVVDEILGDGHKVTGIRLQNVLTGEKTEHQCDGVFMAI
GHAPNAELFKGQLRIDDYGYIETKKTSTETSVPGVFACGDVQDYTYRQAITAAGTGCMAAVDAERFLESIR

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=49.5176848874598, Blast_Score=316, Evalue=1e-87,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=32.3717948717949, Blast_Score=140, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=48.4076433121019, Blast_Score=298, Evalue=6e-82,
Organism=Saccharomyces cerevisiae, GI6321898, Length=312, Percent_Identity=47.1153846153846, Blast_Score=288, Evalue=6e-79,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33922; Mature: 33922

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERDIRDIVIMGTGPAGYTAAIYSGRANLKPLVIEGSQPGGQLMITSEIENFPGFPEGIF
CCCCCEEEEEEECCCCCCEEEEECCCCCCCEEEEECCCCCCEEEEEECHHCCCCCCCCCC
GPELMARMRQQIIRFGVEIAYGSVQDVDLSRTPFSLSLDDGTEIVTRSLIVATGANAKWL
CHHHHHHHHHHHHHHCCEEEECCEECCCCCCCCEEEECCCCHHHHHHEEEEEECCCCEEE
NIDSEKMYRGKGVSACATCDGFFFKQCKVFVVGGGDTAMEEALYLTKFAAEVIIVHRREE
ECCHHHHHCCCCCCEEHHHCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHEEEEEECHHH
FRASKIMSLRAGKNPKISTMLNQVVDEILGDGHKVTGIRLQNVLTGEKTEHQCDGVFMAI
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCEEEEEE
GHAPNAELFKGQLRIDDYGYIETKKTSTETSVPGVFACGDVQDYTYRQAITAAGTGCMAA
CCCCCHHHEEEEEEECCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCEEH
VDAERFLESIR
HHHHHHHHHCC
>Mature Secondary Structure
MERDIRDIVIMGTGPAGYTAAIYSGRANLKPLVIEGSQPGGQLMITSEIENFPGFPEGIF
CCCCCEEEEEEECCCCCCEEEEECCCCCCCEEEEECCCCCCEEEEEECHHCCCCCCCCCC
GPELMARMRQQIIRFGVEIAYGSVQDVDLSRTPFSLSLDDGTEIVTRSLIVATGANAKWL
CHHHHHHHHHHHHHHCCEEEECCEECCCCCCCCEEEECCCCHHHHHHEEEEEECCCCEEE
NIDSEKMYRGKGVSACATCDGFFFKQCKVFVVGGGDTAMEEALYLTKFAAEVIIVHRREE
ECCHHHHHCCCCCCEEHHHCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHEEEEEECHHH
FRASKIMSLRAGKNPKISTMLNQVVDEILGDGHKVTGIRLQNVLTGEKTEHQCDGVFMAI
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCEEEEEE
GHAPNAELFKGQLRIDDYGYIETKKTSTETSVPGVFACGDVQDYTYRQAITAAGTGCMAA
CCCCCHHHEEEEEEECCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCEEH
VDAERFLESIR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]