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The map label for this gene is kdsC [H]

Identifier: 119357002

GI number: 119357002

Start: 1339452

End: 1339979

Strand: Direct

Name: kdsC [H]

Synonym: Cpha266_1186

Alternate gene names: 119357002

Gene position: 1339452-1339979 (Clockwise)

Preceding gene: 119357001

Following gene: 119357003

Centisome position: 42.74

GC content: 48.67

Gene sequence:

>528_bases
ATGCTGTCACTTACAAACGAAGAGCTTGTTCTACGGGCCAACAGGATTAAGCTGGTTCTTTCGGACAACGATGGCGTCTT
TACCGATAACGGTGTTTATTACGGGGCGAACGGTGAAGTTATGAAGCGTTATTCGATCCGTGACGGGATGGGTGTTGAAC
GGCTCCAGGGTTACGGTATCGATACTGCTATCATGACAGGAGAGCGCTCTGCGAGCATCGCCATGCGGGCAGAGAAGCTT
AAAATGAAACACCTCTATCTTGGTGCCAGCGATAAATTATCGAAACTGGATGATGTTTTGTCGGATACGGGTTTGTCTTT
GCATGAGTTGGCGTATATCGGAGATGATGTCAATGATGCCGCCATCATGAAAGAGATTGCTGCGGTTGGTCTTACGGCCT
GTCCAAACGATGCGCTTGATTTTGTAAGGCCGTTTACCCATTACACCGCTTTACATAATGGCGGGTACGGTGCTTTTCGT
GATTTTGCGGAGTGGCTGATCTCCCTTAAAATCCTTGCTCGGGCGTGA

Upstream 100 bases:

>100_bases
GCGAAAGGCTTTGATATCACAGAAAAGTAATATATTTGCCCTGATAAATTCCGGGTATTGGTCGCCCGGTTCTTTTTTGA
GGTTTTCAAAGCTTTTTATC

Downstream 100 bases:

>100_bases
CGTTGATGCGACAGGTCAAGCCGTCGTTTCGGCGATAAAGATGTTTTTTTATTCATTTATTTTTTGAGGTTATGGCTGAA
GTGCAAATCGGGAACAGAAA

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MLSLTNEELVLRANRIKLVLSDNDGVFTDNGVYYGANGEVMKRYSIRDGMGVERLQGYGIDTAIMTGERSASIAMRAEKL
KMKHLYLGASDKLSKLDDVLSDTGLSLHELAYIGDDVNDAAIMKEIAAVGLTACPNDALDFVRPFTHYTALHNGGYGAFR
DFAEWLISLKILARA

Sequences:

>Translated_175_residues
MLSLTNEELVLRANRIKLVLSDNDGVFTDNGVYYGANGEVMKRYSIRDGMGVERLQGYGIDTAIMTGERSASIAMRAEKL
KMKHLYLGASDKLSKLDDVLSDTGLSLHELAYIGDDVNDAAIMKEIAAVGLTACPNDALDFVRPFTHYTALHNGGYGAFR
DFAEWLISLKILARA
>Mature_175_residues
MLSLTNEELVLRANRIKLVLSDNDGVFTDNGVYYGANGEVMKRYSIRDGMGVERLQGYGIDTAIMTGERSASIAMRAEKL
KMKHLYLGASDKLSKLDDVLSDTGLSLHELAYIGDDVNDAAIMKEIAAVGLTACPNDALDFVRPFTHYTALHNGGYGAFR
DFAEWLISLKILARA

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=149, Percent_Identity=30.8724832214765, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI2367202, Length=163, Percent_Identity=33.1288343558282, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19210; Mature: 19210

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLTNEELVLRANRIKLVLSDNDGVFTDNGVYYGANGEVMKRYSIRDGMGVERLQGYGI
CCCCCCCCEEEEEEEEEEEEECCCCEEECCCEEECCCCCEEEEEECCCCCCHHHHHCCCC
DTAIMTGERSASIAMRAEKLKMKHLYLGASDKLSKLDDVLSDTGLSLHELAYIGDDVNDA
CEEEECCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCHH
AIMKEIAAVGLTACPNDALDFVRPFTHYTALHNGGYGAFRDFAEWLISLKILARA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSLTNEELVLRANRIKLVLSDNDGVFTDNGVYYGANGEVMKRYSIRDGMGVERLQGYGI
CCCCCCCCEEEEEEEEEEEEECCCCEEECCCEEECCCCCEEEEEECCCCCCHHHHHCCCC
DTAIMTGERSASIAMRAEKLKMKHLYLGASDKLSKLDDVLSDTGLSLHELAYIGDDVNDA
CEEEECCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCHH
AIMKEIAAVGLTACPNDALDFVRPFTHYTALHNGGYGAFRDFAEWLISLKILARA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]