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The map label for this gene is cobP [H]

Identifier: 119356825

GI number: 119356825

Start: 1136991

End: 1137506

Strand: Direct

Name: cobP [H]

Synonym: Cpha266_0998

Alternate gene names: 119356825

Gene position: 1136991-1137506 (Clockwise)

Preceding gene: 119356816

Following gene: 119356826

Centisome position: 36.28

GC content: 49.81

Gene sequence:

>516_bases
ATGCACAGAATTATTTATGTGACGGGAGGCGCCCGGAGTGGAAAAAGCTCTTATGCGCTGTCGCTTGCCCTTGGTTATGC
CAACAGGTATTTTCTGGCAACAGCAGAGCCTTTTGATGACGAGATGCAGGAACGTATCCGGAAGCACCGACTTGAGCGCA
AGGAGGGGTTTACAACTATCGAGGAACCTCTTTTTCTTGATCGGGCACTTTCTTTGCTGCCTGTTTCTGCTGATGTGGTG
CTTCTCGATTGTCTGACCGTCTGGAGCGGAAACATGATGCATCATTTAGAGGATGACAAGGCAATTGATAAATGCATAAC
GGCACTGCTTGCAGCGCTGCCCGCGCTCTCATGCGACTGTATTGTCGTTTCTAATGAGGTCGGCATGGGGATCGTTCCTG
AAAATCCTTTGGCAAGAAGATTTCGGGATATTGCCGGCATCGTGAACCAGAAGGTTGCCGCTCTTGCAACAGATGCATAC
CTGCTTTGCAGCGGCATTCCGCTTAAGCTCAGATAA

Upstream 100 bases:

>100_bases
CAACAGCTTTTGTTCCGCCCGCTGCATTTGCCTGATTTTTGTTAAGTTAGGTTTTTTATTGTCAGTCCTCACTGAAACGA
TACGGGTTACGGGATCAGGT

Downstream 100 bases:

>100_bases
AACAAAAATAAAAAGTATTTAATAAAAAGCTGAACAGGAATACGATACATATGCGTCAAAAACTTGAAGAGCTGCTTACC
GCAATTCAATCTCCCGATCG

Product: adenosylcobinamide kinase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MHRIIYVTGGARSGKSSYALSLALGYANRYFLATAEPFDDEMQERIRKHRLERKEGFTTIEEPLFLDRALSLLPVSADVV
LLDCLTVWSGNMMHHLEDDKAIDKCITALLAALPALSCDCIVVSNEVGMGIVPENPLARRFRDIAGIVNQKVAALATDAY
LLCSGIPLKLR

Sequences:

>Translated_171_residues
MHRIIYVTGGARSGKSSYALSLALGYANRYFLATAEPFDDEMQERIRKHRLERKEGFTTIEEPLFLDRALSLLPVSADVV
LLDCLTVWSGNMMHHLEDDKAIDKCITALLAALPALSCDCIVVSNEVGMGIVPENPLARRFRDIAGIVNQKVAALATDAY
LLCSGIPLKLR
>Mature_171_residues
MHRIIYVTGGARSGKSSYALSLALGYANRYFLATAEPFDDEMQERIRKHRLERKEGFTTIEEPLFLDRALSLLPVSADVV
LLDCLTVWSGNMMHHLEDDKAIDKCITALLAALPALSCDCIVVSNEVGMGIVPENPLARRFRDIAGIVNQKVAALATDAY
LLCSGIPLKLR

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=180, Percent_Identity=41.6666666666667, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18862; Mature: 18862

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRIIYVTGGARSGKSSYALSLALGYANRYFLATAEPFDDEMQERIRKHRLERKEGFTTI
CCEEEEEECCCCCCCCCEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCH
EEPLFLDRALSLLPVSADVVLLDCLTVWSGNMMHHLEDDKAIDKCITALLAALPALSCDC
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCE
IVVSNEVGMGIVPENPLARRFRDIAGIVNQKVAALATDAYLLCSGIPLKLR
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MHRIIYVTGGARSGKSSYALSLALGYANRYFLATAEPFDDEMQERIRKHRLERKEGFTTI
CCEEEEEECCCCCCCCCEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCH
EEPLFLDRALSLLPVSADVVLLDCLTVWSGNMMHHLEDDKAIDKCITALLAALPALSCDC
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCE
IVVSNEVGMGIVPENPLARRFRDIAGIVNQKVAALATDAYLLCSGIPLKLR
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]