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The map label for this gene is dnaC [H]

Identifier: 118578973

GI number: 118578973

Start: 570917

End: 572293

Strand: Direct

Name: dnaC [H]

Synonym: Ppro_0534

Alternate gene names: 118578973

Gene position: 570917-572293 (Clockwise)

Preceding gene: 118578972

Following gene: 118578974

Centisome position: 14.24

GC content: 62.89

Gene sequence:

>1377_bases
ATGACCAACCCCGATCTTCGCAAACTCCCCCCCCAGAGCCTGGAGGCTGAAATGTCCGTGCTGGGGGGCATCCTGATCGA
TAACGATGCCATCAACCGGGTGCTGGAAATCCTCGGCGCGGAAGACTTCTACCGCGAGAGCCACCGCAAGATCTTCCAGG
CCATGATGCGCCTCTCGGACCAGCGCGAGCCGTGCGACCTGATCACCATGACCGACATGCTCAAGAAGCAGGGTGAACTG
GAGGAGGTGGGGGGCGCCCCCTACCTGTTGACCCTGGTGGACTACGTTCCCACCGCGGCCAACATCGCCTACTACTGCAA
GATCGTGAAGGAAAAGGCGGTCAACCGTAAGCTGATCAGCGTGGCCACCGAGATCGTGACCCGGGGGTACGACGAGCAGG
CCGATATCAACGAACTGCTGGATCTGGCCCAGAAGAACATCTACGAGATCTCCGAGAACAAGCTGCGCCCCCAGTACGTG
CCGGTGCAGGCGGTGCTCAAGGAAGCCTTCACCATCCTGAAGACCCTGCACGACCGCAAGGAGCATGTCACCGGCGTGCC
CACCGGTTATGTGGACCTGGACCACATGACCGCCGGCTTCCAGCCCGGCGACCTGATTATCGTGGCCGCGCGCCCCTCCA
TGGGCAAGACCACCCTGGCGCTGAACGTGGCCGAATACGCTAGCGCCGATCCCCACAACAAGAAGAAGGTCCCCTCGGTG
ATCTTCTCCCTGGAGATGGGCAAGGAACAGCTGGTGATGCGTTTTTTGGCCTCCATCGCCAAGGTGGACTTCGGCAGGAT
GCGCACCGGCCACTTCCTGGATTCGGACTGGCCCCGCCTCACCAGGGCGGCCGGCATCCTGCACGACGCCAAGATATTCA
TCGACGACACGCCGGCCATCTCGGTGCTGGAGCTGCGCTCCAAGGCGCGGCGCCTGAAGAGCGAGCACGACATCGGCCTG
ATCATCATCGACTACCTGCAGCTGATGCGGGGGGGCGCCAACCCGGAATCCCGCCAGCAGGAGATCTCGGAGATCTCCCG
CTCCCTGAAGGCGCTGGCCAAGGAGCTGAACGTGCCGGTGATCGCCCTGTCCCAGCTCAACCGCGAACTGGAAAAGCGCG
CCGACAAGCGCCCCATGATGAGCGACCTGCGCGAGTCGGGCGCCATCGAACAGGATGCCGACGTGATCATGTTCGTCTAC
CGCGAATCGGTGTACTGCGAGCAGTGCCGCAAGCGGGACGGCACCTGCACCCAGAACCACGAACGCAACTCCGAGATCAT
CATCGGCAAGCAGCGTAACGGCGCCATCGGCACCGTCAACCTGGCCTTCTTCGGAGAGCACACCCGCTTCGAGAACCTGA
GCGCCCGGGAAGGCTGA

Upstream 100 bases:

>100_bases
TCCCGCGCAGCTTCCCGGATCAAGGCCCTGCCCCTGATCCGGTCGGGCCCGTAGGGAAGATTACCCGCACTTCAATGTTT
TCCGGAGAAGAAATACCCCC

Downstream 100 bases:

>100_bases
GGCGCCCCGGCGGTTCCCGCGGTGAGGGAGTTTTGGCGTAGTGCCAAGGCACATTCTATGGTATGAACATCCAGTTACGG
GAGAGGAACCATGACCGAGT

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTNPDLRKLPPQSLEAEMSVLGGILIDNDAINRVLEILGAEDFYRESHRKIFQAMMRLSDQREPCDLITMTDMLKKQGEL
EEVGGAPYLLTLVDYVPTAANIAYYCKIVKEKAVNRKLISVATEIVTRGYDEQADINELLDLAQKNIYEISENKLRPQYV
PVQAVLKEAFTILKTLHDRKEHVTGVPTGYVDLDHMTAGFQPGDLIIVAARPSMGKTTLALNVAEYASADPHNKKKVPSV
IFSLEMGKEQLVMRFLASIAKVDFGRMRTGHFLDSDWPRLTRAAGILHDAKIFIDDTPAISVLELRSKARRLKSEHDIGL
IIIDYLQLMRGGANPESRQQEISEISRSLKALAKELNVPVIALSQLNRELEKRADKRPMMSDLRESGAIEQDADVIMFVY
RESVYCEQCRKRDGTCTQNHERNSEIIIGKQRNGAIGTVNLAFFGEHTRFENLSAREG

Sequences:

>Translated_458_residues
MTNPDLRKLPPQSLEAEMSVLGGILIDNDAINRVLEILGAEDFYRESHRKIFQAMMRLSDQREPCDLITMTDMLKKQGEL
EEVGGAPYLLTLVDYVPTAANIAYYCKIVKEKAVNRKLISVATEIVTRGYDEQADINELLDLAQKNIYEISENKLRPQYV
PVQAVLKEAFTILKTLHDRKEHVTGVPTGYVDLDHMTAGFQPGDLIIVAARPSMGKTTLALNVAEYASADPHNKKKVPSV
IFSLEMGKEQLVMRFLASIAKVDFGRMRTGHFLDSDWPRLTRAAGILHDAKIFIDDTPAISVLELRSKARRLKSEHDIGL
IIIDYLQLMRGGANPESRQQEISEISRSLKALAKELNVPVIALSQLNRELEKRADKRPMMSDLRESGAIEQDADVIMFVY
RESVYCEQCRKRDGTCTQNHERNSEIIIGKQRNGAIGTVNLAFFGEHTRFENLSAREG
>Mature_457_residues
TNPDLRKLPPQSLEAEMSVLGGILIDNDAINRVLEILGAEDFYRESHRKIFQAMMRLSDQREPCDLITMTDMLKKQGELE
EVGGAPYLLTLVDYVPTAANIAYYCKIVKEKAVNRKLISVATEIVTRGYDEQADINELLDLAQKNIYEISENKLRPQYVP
VQAVLKEAFTILKTLHDRKEHVTGVPTGYVDLDHMTAGFQPGDLIIVAARPSMGKTTLALNVAEYASADPHNKKKVPSVI
FSLEMGKEQLVMRFLASIAKVDFGRMRTGHFLDSDWPRLTRAAGILHDAKIFIDDTPAISVLELRSKARRLKSEHDIGLI
IIDYLQLMRGGANPESRQQEISEISRSLKALAKELNVPVIALSQLNRELEKRADKRPMMSDLRESGAIEQDADVIMFVYR
ESVYCEQCRKRDGTCTQNHERNSEIIIGKQRNGAIGTVNLAFFGEHTRFENLSAREG

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=454, Percent_Identity=51.7621145374449, Blast_Score=430, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 51600; Mature: 51469

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPDLRKLPPQSLEAEMSVLGGILIDNDAINRVLEILGAEDFYRESHRKIFQAMMRLSD
CCCCCCCCCCCHHHHHHHHHHCCCEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
QREPCDLITMTDMLKKQGELEEVGGAPYLLTLVDYVPTAANIAYYCKIVKEKAVNRKLIS
CCCCCHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VATEIVTRGYDEQADINELLDLAQKNIYEISENKLRPQYVPVQAVLKEAFTILKTLHDRK
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EHVTGVPTGYVDLDHMTAGFQPGDLIIVAARPSMGKTTLALNVAEYASADPHNKKKVPSV
HHCCCCCCCCEEHHHHHCCCCCCCEEEEEECCCCCCEEEEEEHHHHCCCCCCCHHHHHHH
IFSLEMGKEQLVMRFLASIAKVDFGRMRTGHFLDSDWPRLTRAAGILHDAKIFIDDTPAI
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCH
SVLELRSKARRLKSEHDIGLIIIDYLQLMRGGANPESRQQEISEISRSLKALAKELNVPV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
IALSQLNRELEKRADKRPMMSDLRESGAIEQDADVIMFVYRESVYCEQCRKRDGTCTQNH
EEHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCC
ERNSEIIIGKQRNGAIGTVNLAFFGEHTRFENLSAREG
CCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TNPDLRKLPPQSLEAEMSVLGGILIDNDAINRVLEILGAEDFYRESHRKIFQAMMRLSD
CCCCCCCCCCHHHHHHHHHHCCCEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
QREPCDLITMTDMLKKQGELEEVGGAPYLLTLVDYVPTAANIAYYCKIVKEKAVNRKLIS
CCCCCHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VATEIVTRGYDEQADINELLDLAQKNIYEISENKLRPQYVPVQAVLKEAFTILKTLHDRK
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EHVTGVPTGYVDLDHMTAGFQPGDLIIVAARPSMGKTTLALNVAEYASADPHNKKKVPSV
HHCCCCCCCCEEHHHHHCCCCCCCEEEEEECCCCCCEEEEEEHHHHCCCCCCCHHHHHHH
IFSLEMGKEQLVMRFLASIAKVDFGRMRTGHFLDSDWPRLTRAAGILHDAKIFIDDTPAI
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCH
SVLELRSKARRLKSEHDIGLIIIDYLQLMRGGANPESRQQEISEISRSLKALAKELNVPV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
IALSQLNRELEKRADKRPMMSDLRESGAIEQDADVIMFVYRESVYCEQCRKRDGTCTQNH
EEHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCC
ERNSEIIIGKQRNGAIGTVNLAFFGEHTRFENLSAREG
CCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]