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The map label for this gene is cobS [H]

Identifier: 118578651

GI number: 118578651

Start: 204969

End: 205892

Strand: Direct

Name: cobS [H]

Synonym: Ppro_0207

Alternate gene names: 118578651

Gene position: 204969-205892 (Clockwise)

Preceding gene: 118578650

Following gene: 118578652

Centisome position: 5.11

GC content: 55.19

Gene sequence:

>924_bases
ATGAAATATAGCATCAAGGACATCTTCAATATTCCCGTGAAAGAGAGTCTCTGCGTAGAAGGTCGGCCTCAGACCGACAA
CCCCTTCATCCCTGAAGTTGACAGCGACTATGTGTTCAGGAAGGAAATCCTGTCGGATGTACTTTCCTGGTACATGATGG
GCGCCAACGACGGTCTGTACCTGACCGGTCCGACCGGCAGCGGCAAGTCTTCGATCGTTTTGCAGACCGCCGCCCGGCTC
AATATACCGGTCATGGTCGTCACAGGGCACAGCAGACTCGAAACCCCGGAACTTGTGGGGCATCACGTAATTGTCAACAA
CTCGATGGAGTATGTCTACGGACCGCTAGCCATGGCCATGAAGGAAGGTCACTGGTTCCTGCTGGACGAGATCGACTTGC
TCGATCCCGCAACTGCAGCAGGTTTGAACGGCATAGTCGAAGGAAGACCCCTCACCATTCCGGAAAAGGGTGGTGAAGTC
ATCAAACCGGCACCGGGCTTTCGTTTTATTGCGACAGCCAACACCGCCGGCAGCGGTGATCGCTCAGGTCTCTATCAAGG
GACCTTACGGCAGAACGGCGCATTTCTGGATCGCTTCTGGATGGTTGAAGTCGACTACCCTGACGAAGTCCAGGAAAGAC
AGATTCTGGCCAAAGCCATGCCCAGTCTGGCTGATACGGTCAGGGAAGCGCTGGTATCGTATGCCAACGAAATCCGCAAA
CTCTTCATCAAAGGGGAAATAGAAGTCACCTTCTCCACCAGAACCCTCGTCAGATGGGCGAAGCTTGTGTATCTCTTCCG
CCCGGCATCTGCCGAAGGGAAAAACCCGATCATCCATGCTCTCGACCGTGCTCTCGGGTACCGAGCAGAGCCGGAAAGCC
GCGAGGCGTTGCACGAACTGGCGCAACGCGTCTTCGGCGGATAG

Upstream 100 bases:

>100_bases
ATCGTTTTGGAGCATCTGAAAACAGGGCGCGATCTCAACGACCTCATCGAGGAAGCTGACTTCGCGGCACTTAACCAAAT
CGGACAAGGAGCTGATCACC

Downstream 100 bases:

>100_bases
GGGGTGCTGCATGGCATTACGACAGCATCTTCACCTCCAGTGCAACACTGCGGCTGGCGGCAAGTTCTGGATCGCCCAGA
TTCATGACGATCCGCCACGG

Product: ATPase

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKYSIKDIFNIPVKESLCVEGRPQTDNPFIPEVDSDYVFRKEILSDVLSWYMMGANDGLYLTGPTGSGKSSIVLQTAARL
NIPVMVVTGHSRLETPELVGHHVIVNNSMEYVYGPLAMAMKEGHWFLLDEIDLLDPATAAGLNGIVEGRPLTIPEKGGEV
IKPAPGFRFIATANTAGSGDRSGLYQGTLRQNGAFLDRFWMVEVDYPDEVQERQILAKAMPSLADTVREALVSYANEIRK
LFIKGEIEVTFSTRTLVRWAKLVYLFRPASAEGKNPIIHALDRALGYRAEPESREALHELAQRVFGG

Sequences:

>Translated_307_residues
MKYSIKDIFNIPVKESLCVEGRPQTDNPFIPEVDSDYVFRKEILSDVLSWYMMGANDGLYLTGPTGSGKSSIVLQTAARL
NIPVMVVTGHSRLETPELVGHHVIVNNSMEYVYGPLAMAMKEGHWFLLDEIDLLDPATAAGLNGIVEGRPLTIPEKGGEV
IKPAPGFRFIATANTAGSGDRSGLYQGTLRQNGAFLDRFWMVEVDYPDEVQERQILAKAMPSLADTVREALVSYANEIRK
LFIKGEIEVTFSTRTLVRWAKLVYLFRPASAEGKNPIIHALDRALGYRAEPESREALHELAQRVFGG
>Mature_307_residues
MKYSIKDIFNIPVKESLCVEGRPQTDNPFIPEVDSDYVFRKEILSDVLSWYMMGANDGLYLTGPTGSGKSSIVLQTAARL
NIPVMVVTGHSRLETPELVGHHVIVNNSMEYVYGPLAMAMKEGHWFLLDEIDLLDPATAAGLNGIVEGRPLTIPEKGGEV
IKPAPGFRFIATANTAGSGDRSGLYQGTLRQNGAFLDRFWMVEVDYPDEVQERQILAKAMPSLADTVREALVSYANEIRK
LFIKGEIEVTFSTRTLVRWAKLVYLFRPASAEGKNPIIHALDRALGYRAEPESREALHELAQRVFGG

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=206, Percent_Identity=28.6407766990291, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323135, Length=210, Percent_Identity=30, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI161076560, Length=204, Percent_Identity=25.9803921568627, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076562, Length=204, Percent_Identity=25.9803921568627, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 34042; Mature: 34042

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYSIKDIFNIPVKESLCVEGRPQTDNPFIPEVDSDYVFRKEILSDVLSWYMMGANDGLY
CCCCHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCEE
LTGPTGSGKSSIVLQTAARLNIPVMVVTGHSRLETPELVGHHVIVNNSMEYVYGPLAMAM
EECCCCCCCCEEEEEEHHHCCCCEEEEECCCCCCCHHHHCCEEEEECCHHHHHHHHHHHH
KEGHWFLLDEIDLLDPATAAGLNGIVEGRPLTIPEKGGEVIKPAPGFRFIATANTAGSGD
HCCCEEEEECCCCCCCHHHHCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEECCCCCCCC
RSGLYQGTLRQNGAFLDRFWMVEVDYPDEVQERQILAKAMPSLADTVREALVSYANEIRK
CCCCEECHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFIKGEIEVTFSTRTLVRWAKLVYLFRPASAEGKNPIIHALDRALGYRAEPESREALHEL
EEEECEEEEEECHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
AQRVFGG
HHHHHCC
>Mature Secondary Structure
MKYSIKDIFNIPVKESLCVEGRPQTDNPFIPEVDSDYVFRKEILSDVLSWYMMGANDGLY
CCCCHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCEE
LTGPTGSGKSSIVLQTAARLNIPVMVVTGHSRLETPELVGHHVIVNNSMEYVYGPLAMAM
EECCCCCCCCEEEEEEHHHCCCCEEEEECCCCCCCHHHHCCEEEEECCHHHHHHHHHHHH
KEGHWFLLDEIDLLDPATAAGLNGIVEGRPLTIPEKGGEVIKPAPGFRFIATANTAGSGD
HCCCEEEEECCCCCCCHHHHCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEECCCCCCCC
RSGLYQGTLRQNGAFLDRFWMVEVDYPDEVQERQILAKAMPSLADTVREALVSYANEIRK
CCCCEECHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFIKGEIEVTFSTRTLVRWAKLVYLFRPASAEGKNPIIHALDRALGYRAEPESREALHEL
EEEECEEEEEECHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
AQRVFGG
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]