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The map label for this gene is moeA [H]

Identifier: 118479857

GI number: 118479857

Start: 4515541

End: 4516830

Strand: Reverse

Name: moeA [H]

Synonym: BALH_4295

Alternate gene names: 118479857

Gene position: 4516830-4515541 (Counterclockwise)

Preceding gene: 118479859

Following gene: 118479856

Centisome position: 85.92

GC content: 41.78

Gene sequence:

>1290_bases
ATGGTAGAAAAACGAATTCCGATTCAAGTTGCTGAGGCAGTAGAGAGAGTAATGGAATATGCGAAAATTGGTGAAGTAGA
AGAGGTTTCTATTACGGAAAGTTACGGGAGAATTCTTGGGGAGGATGTTGTCTCTGATCATGACGTTCCTCATTTTGATC
GTTCTCCTTACGATGGTTTCGCAATTCGAGCAGAAGATACGAAAGAAGCAAATCAAGAGAATGCAATTGAGTTTGAAGTA
ATAGGAGAAATCGGGGCGGGGTCTGTTTTTACAGAAAAAGTAGGATCTTTTCAGGCGGTTCGTATTATGACAGGAGCAGC
TATTCCAGCGGATTGTAATGCAGTCGTAATGCTAGAACTGACGGAAGGTTTTGAGAAGAACGGAAAAACATATATGAAGT
TAAAGCGTCCTTTTCATAGTGGCGACAATGTGTCATTTAAAGGGGAAGATATAAAACAAAATCAAGTTCTCGTTCAGGAA
GGTGCTGTAATCAATCCAGGTGTTGCGGCCTTATTAGCGACGTTTGGATACAGTAATGTGAAGGTTGTAAAACAGCCAGT
TGTTGGTATTGTGACGACAGGAAGTGAACTGTTAGAAGTACATGAGTCATTACAGCCGGGGAAAATTAGAAATAGTAACT
CTTATATGATTGCCGCCCAAATTATGAAAGCTGGGGGTAAAGTCCGTTATTATGGTCAACTTGCCGACGAGTTAGATGCA
TGTTTTACAGCCGTTCAATCGGCGATAGATGAGGTGGATATTTTAATTACGACAGGCGGTGTGTCGGTAGGAGATTATGA
CTACTTACCGGCTATTTATGAAAGGTTACAGGCGAATGTACTCTTTAATAAAATAGCAATGAGACCGGGCAGTGTAACGA
CAGTAGCTGAAGTGGATGGAAAGTTACTTTTCGGTTTATCAGGGAATCCGTCAGCTTGTTATGTGGGATTTGAGTTATTT
GTGCATCCGGTTATAAAAACTTATTTGTATGCGAAGGAACCACACGTATATAGAGCAGATGCTATTTTGCAAAAAGATTT
TCCAAAACCAAATCCGTTTACTCGTTTTGTAAGAGCAAAGGTGACAATCGTGGACGGGGCATTACACGCGATGCCGGTCG
GTTTAGATAAATCGAGTGCGGTATCTTCTCTTGCAGATGCGAATGCTTTTATTGTGCTGCCTGGAGGAACGAGAGGCTTT
GAGGCAGGGATGAAAGTGTCTGTATTATTGTTAGAGAACGCTGAGGGATGTGATTGGCCATGGGCAAAGCCCCTTCAATC
TTACAAATAG

Upstream 100 bases:

>100_bases
TGTGTGAATGAAGACATGGAATTCCTCCTTGAAGTAATTTCTATTTAATATATAAAGTTTAATCGAGATAAAAAAAATTG
CAAATATGAGGTGAGAAACG

Downstream 100 bases:

>100_bases
TAGGGTATCAAAATAGCGGGAAAACAACACTTGTTGAGAAAGTTGTGTATGCATTAGCTGAACGAAAAATGAAAGTTGCT
ACCATTAAACATCACGGACA

Product: molybdopterin biosynthesis protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MVEKRIPIQVAEAVERVMEYAKIGEVEEVSITESYGRILGEDVVSDHDVPHFDRSPYDGFAIRAEDTKEANQENAIEFEV
IGEIGAGSVFTEKVGSFQAVRIMTGAAIPADCNAVVMLELTEGFEKNGKTYMKLKRPFHSGDNVSFKGEDIKQNQVLVQE
GAVINPGVAALLATFGYSNVKVVKQPVVGIVTTGSELLEVHESLQPGKIRNSNSYMIAAQIMKAGGKVRYYGQLADELDA
CFTAVQSAIDEVDILITTGGVSVGDYDYLPAIYERLQANVLFNKIAMRPGSVTTVAEVDGKLLFGLSGNPSACYVGFELF
VHPVIKTYLYAKEPHVYRADAILQKDFPKPNPFTRFVRAKVTIVDGALHAMPVGLDKSSAVSSLADANAFIVLPGGTRGF
EAGMKVSVLLLENAEGCDWPWAKPLQSYK

Sequences:

>Translated_429_residues
MVEKRIPIQVAEAVERVMEYAKIGEVEEVSITESYGRILGEDVVSDHDVPHFDRSPYDGFAIRAEDTKEANQENAIEFEV
IGEIGAGSVFTEKVGSFQAVRIMTGAAIPADCNAVVMLELTEGFEKNGKTYMKLKRPFHSGDNVSFKGEDIKQNQVLVQE
GAVINPGVAALLATFGYSNVKVVKQPVVGIVTTGSELLEVHESLQPGKIRNSNSYMIAAQIMKAGGKVRYYGQLADELDA
CFTAVQSAIDEVDILITTGGVSVGDYDYLPAIYERLQANVLFNKIAMRPGSVTTVAEVDGKLLFGLSGNPSACYVGFELF
VHPVIKTYLYAKEPHVYRADAILQKDFPKPNPFTRFVRAKVTIVDGALHAMPVGLDKSSAVSSLADANAFIVLPGGTRGF
EAGMKVSVLLLENAEGCDWPWAKPLQSYK
>Mature_429_residues
MVEKRIPIQVAEAVERVMEYAKIGEVEEVSITESYGRILGEDVVSDHDVPHFDRSPYDGFAIRAEDTKEANQENAIEFEV
IGEIGAGSVFTEKVGSFQAVRIMTGAAIPADCNAVVMLELTEGFEKNGKTYMKLKRPFHSGDNVSFKGEDIKQNQVLVQE
GAVINPGVAALLATFGYSNVKVVKQPVVGIVTTGSELLEVHESLQPGKIRNSNSYMIAAQIMKAGGKVRYYGQLADELDA
CFTAVQSAIDEVDILITTGGVSVGDYDYLPAIYERLQANVLFNKIAMRPGSVTTVAEVDGKLLFGLSGNPSACYVGFELF
VHPVIKTYLYAKEPHVYRADAILQKDFPKPNPFTRFVRAKVTIVDGALHAMPVGLDKSSAVSSLADANAFIVLPGGTRGF
EAGMKVSVLLLENAEGCDWPWAKPLQSYK

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=398, Percent_Identity=32.6633165829146, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI10880983, Length=398, Percent_Identity=32.6633165829146, Blast_Score=180, Evalue=3e-45,
Organism=Escherichia coli, GI1787049, Length=374, Percent_Identity=31.5508021390374, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI25147659, Length=390, Percent_Identity=27.4358974358974, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17562606, Length=366, Percent_Identity=23.7704918032787, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17136978, Length=360, Percent_Identity=30, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24638841, Length=360, Percent_Identity=30, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 46614; Mature: 46614

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEKRIPIQVAEAVERVMEYAKIGEVEEVSITESYGRILGEDVVSDHDVPHFDRSPYDGF
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
AIRAEDTKEANQENAIEFEVIGEIGAGSVFTEKVGSFQAVRIMTGAAIPADCNAVVMLEL
EEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCEEEEEEEECCCCCCCCCEEEEEEE
TEGFEKNGKTYMKLKRPFHSGDNVSFKGEDIKQNQVLVQEGAVINPGVAALLATFGYSNV
ECCCCCCCCEEEEEECCCCCCCCEEECCCCCCCCEEEEECCCEECCCHHHHHHHHCCCCE
KVVKQPVVGIVTTGSELLEVHESLQPGKIRNSNSYMIAAQIMKAGGKVRYYGQLADELDA
EEEECCCEEEEECCHHHHHHHHCCCCCCEECCCCEEEEEEHHHCCCCEEEEHHHHHHHHH
CFTAVQSAIDEVDILITTGGVSVGDYDYLPAIYERLQANVLFNKIAMRPGSVTTVAEVDG
HHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
KLLFGLSGNPSACYVGFELFVHPVIKTYLYAKEPHVYRADAILQKDFPKPNPFTRFVRAK
EEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCHHHHEEEEE
VTIVDGALHAMPVGLDKSSAVSSLADANAFIVLPGGTRGFEAGMKVSVLLLENAEGCDWP
EEEEECCHHHEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCC
WAKPLQSYK
CCCHHHCCC
>Mature Secondary Structure
MVEKRIPIQVAEAVERVMEYAKIGEVEEVSITESYGRILGEDVVSDHDVPHFDRSPYDGF
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
AIRAEDTKEANQENAIEFEVIGEIGAGSVFTEKVGSFQAVRIMTGAAIPADCNAVVMLEL
EEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCEEEEEEEECCCCCCCCCEEEEEEE
TEGFEKNGKTYMKLKRPFHSGDNVSFKGEDIKQNQVLVQEGAVINPGVAALLATFGYSNV
ECCCCCCCCEEEEEECCCCCCCCEEECCCCCCCCEEEEECCCEECCCHHHHHHHHCCCCE
KVVKQPVVGIVTTGSELLEVHESLQPGKIRNSNSYMIAAQIMKAGGKVRYYGQLADELDA
EEEECCCEEEEECCHHHHHHHHCCCCCCEECCCCEEEEEEHHHCCCCEEEEHHHHHHHHH
CFTAVQSAIDEVDILITTGGVSVGDYDYLPAIYERLQANVLFNKIAMRPGSVTTVAEVDG
HHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
KLLFGLSGNPSACYVGFELFVHPVIKTYLYAKEPHVYRADAILQKDFPKPNPFTRFVRAK
EEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCHHHHEEEEE
VTIVDGALHAMPVGLDKSSAVSSLADANAFIVLPGGTRGFEAGMKVSVLLLENAEGCDWP
EEEEECCHHHEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCC
WAKPLQSYK
CCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]