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The map label for this gene is moeB [H]

Identifier: 118479859

GI number: 118479859

Start: 4517438

End: 4518451

Strand: Reverse

Name: moeB [H]

Synonym: BALH_4297

Alternate gene names: 118479859

Gene position: 4518451-4517438 (Counterclockwise)

Preceding gene: 118479860

Following gene: 118479857

Centisome position: 85.95

GC content: 38.07

Gene sequence:

>1014_bases
ATGCAGGAGCGATATTCAAGGCAAATATTATTTTCTGGTGTTGGAGAAGAAGGACAGAGAAAAATTAGAGAGAAGCATGT
GCTTATTATTGGTGCTGGAGCTCTTGGTGCAGCAAATGCAGAAGCGATTGTTAGAGCAGGTGTTGGAAAAATAACAATTG
CGGATCGTGATTATGTAGAGTGGAGTAATTTACAAAGGCAACAATTATATACAGAAGAAGACGCAAAGCAGTATAAACCG
AAGGCGGTAGCAGCGGCAGAGCATTTAAAAGCGATTAATTCTGAGGTGGAAATAAATCCGGTTGTGACTGATGTAACAGT
GCAGGAAATGGAAGAGTTAGTGAAGGATGTAGATTTAATATTAGATGCGACAGATAATTTTGAAACGCGTCTTCTTATTA
ATGATATTTCACAAAAGTATAATATTCCGTGGATATATGGTGGTTGTGTCGGAAGCTACGGAGTAACGTATACAATTGTA
CCAGGGAAAACACCGTGTTTCCGCTGTTTAATGGAGCATCCAGCAAGCGGAGCAACATGTGATACGGCTGGTATTATACA
GCCGGCGGTGCAATTAGTAGTTGCGCATCAAATAACAGAAGCGTTGAAAATATTAGTAGAAGACTTTGAGGCACTTCGTG
AAACGATGTTATCGTTTGATCTTTGGAATAATCAACAGATGGCATTTAAAGTGAATAGACAGAAAAAAGACACGTGTTTA
TCTTGCGGAAGATTACGTACATATCCGAGTTTAACTTTTGAAGCACAAACGAAAACAGAAGTGTTATGTGGCCGGAATAC
AGTACAAATCCGTCCAGGTGTGCGAAATGAATTTAATTTAGAAGAAATTAAAAAACGCTTACAAAGAAGTGTGGATGTAA
AAGCTACTCCGTATTTAGTATCGTTTCTAGTAGAGGAATTTCGTTTTGTTTTATTTACAGATGGTAGGGCGTTTATTCAT
GGGACGAATGATATAAATGTAGCAAAACGCTTATATACAAGATACATAGGTTGA

Upstream 100 bases:

>100_bases
AGAAAAGATAGGTATTCGGATGAACGGACAGAAGAAAGTGCGAAAAATCGTCCGAAAATTGAAATGTCTTATATAGGAGG
ATAAGAAGGGAGGCTATCGT

Downstream 100 bases:

>100_bases
ACCTAAAGAGAAACCCTTTAGGTTCAACAGAGAGAAGATCAAGACTTTCTCGTATAATCTCCACTTTTTCCACCTGTTTT
TTCAAGTAAGTACGTTTCGC

Product: thiamine/molybdopterin biosynthesis MoeB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MQERYSRQILFSGVGEEGQRKIREKHVLIIGAGALGAANAEAIVRAGVGKITIADRDYVEWSNLQRQQLYTEEDAKQYKP
KAVAAAEHLKAINSEVEINPVVTDVTVQEMEELVKDVDLILDATDNFETRLLINDISQKYNIPWIYGGCVGSYGVTYTIV
PGKTPCFRCLMEHPASGATCDTAGIIQPAVQLVVAHQITEALKILVEDFEALRETMLSFDLWNNQQMAFKVNRQKKDTCL
SCGRLRTYPSLTFEAQTKTEVLCGRNTVQIRPGVRNEFNLEEIKKRLQRSVDVKATPYLVSFLVEEFRFVLFTDGRAFIH
GTNDINVAKRLYTRYIG

Sequences:

>Translated_337_residues
MQERYSRQILFSGVGEEGQRKIREKHVLIIGAGALGAANAEAIVRAGVGKITIADRDYVEWSNLQRQQLYTEEDAKQYKP
KAVAAAEHLKAINSEVEINPVVTDVTVQEMEELVKDVDLILDATDNFETRLLINDISQKYNIPWIYGGCVGSYGVTYTIV
PGKTPCFRCLMEHPASGATCDTAGIIQPAVQLVVAHQITEALKILVEDFEALRETMLSFDLWNNQQMAFKVNRQKKDTCL
SCGRLRTYPSLTFEAQTKTEVLCGRNTVQIRPGVRNEFNLEEIKKRLQRSVDVKATPYLVSFLVEEFRFVLFTDGRAFIH
GTNDINVAKRLYTRYIG
>Mature_337_residues
MQERYSRQILFSGVGEEGQRKIREKHVLIIGAGALGAANAEAIVRAGVGKITIADRDYVEWSNLQRQQLYTEEDAKQYKP
KAVAAAEHLKAINSEVEINPVVTDVTVQEMEELVKDVDLILDATDNFETRLLINDISQKYNIPWIYGGCVGSYGVTYTIV
PGKTPCFRCLMEHPASGATCDTAGIIQPAVQLVVAHQITEALKILVEDFEALRETMLSFDLWNNQQMAFKVNRQKKDTCL
SCGRLRTYPSLTFEAQTKTEVLCGRNTVQIRPGVRNEFNLEEIKKRLQRSVDVKATPYLVSFLVEEFRFVLFTDGRAFIH
GTNDINVAKRLYTRYIG

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=267, Percent_Identity=30.7116104868914, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI38045948, Length=170, Percent_Identity=30, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI150417996, Length=171, Percent_Identity=28.6549707602339, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI13376212, Length=181, Percent_Identity=32.5966850828729, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1787048, Length=243, Percent_Identity=32.9218106995885, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082356, Length=248, Percent_Identity=33.8709677419355, Blast_Score=118, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17540406, Length=265, Percent_Identity=32.4528301886792, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI193203301, Length=155, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321903, Length=298, Percent_Identity=29.1946308724832, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6320598, Length=174, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325323, Length=155, Percent_Identity=32.258064516129, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322639, Length=186, Percent_Identity=29.5698924731183, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325438, Length=153, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24582879, Length=305, Percent_Identity=26.5573770491803, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28573937, Length=179, Percent_Identity=29.0502793296089, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641311, Length=163, Percent_Identity=34.3558282208589, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24660640, Length=152, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 38046; Mature: 38046

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQERYSRQILFSGVGEEGQRKIREKHVLIIGAGALGAANAEAIVRAGVGKITIADRDYVE
CCCHHHHHHHHCCCCHHHHHHHHHCEEEEEECCCCCCCCHHHHHHCCCCEEEECCCCCHH
WSNLQRQQLYTEEDAKQYKPKAVAAAEHLKAINSEVEINPVVTDVTVQEMEELVKDVDLI
HHCCHHHHHHCHHHHHHCCCHHHHHHHHHHHHCCCEEECCEEECCCHHHHHHHHHHHHHE
LDATDNFETRLLINDISQKYNIPWIYGGCVGSYGVTYTIVPGKTPCFRCLMEHPASGATC
EECCCCCCEEEEEEHHHHHCCCCEEECCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCC
DTAGIIQPAVQLVVAHQITEALKILVEDFEALRETMLSFDLWNNQQMAFKVNRQKKDTCL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHH
SCGRLRTYPSLTFEAQTKTEVLCGRNTVQIRPGVRNEFNLEEIKKRLQRSVDVKATPYLV
HCCCCCCCCCEEEECCCCHHHEECCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHHH
SFLVEEFRFVLFTDGRAFIHGTNDINVAKRLYTRYIG
HHHHHHCEEEEEECCEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQERYSRQILFSGVGEEGQRKIREKHVLIIGAGALGAANAEAIVRAGVGKITIADRDYVE
CCCHHHHHHHHCCCCHHHHHHHHHCEEEEEECCCCCCCCHHHHHHCCCCEEEECCCCCHH
WSNLQRQQLYTEEDAKQYKPKAVAAAEHLKAINSEVEINPVVTDVTVQEMEELVKDVDLI
HHCCHHHHHHCHHHHHHCCCHHHHHHHHHHHHCCCEEECCEEECCCHHHHHHHHHHHHHE
LDATDNFETRLLINDISQKYNIPWIYGGCVGSYGVTYTIVPGKTPCFRCLMEHPASGATC
EECCCCCCEEEEEEHHHHHCCCCEEECCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCC
DTAGIIQPAVQLVVAHQITEALKILVEDFEALRETMLSFDLWNNQQMAFKVNRQKKDTCL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHH
SCGRLRTYPSLTFEAQTKTEVLCGRNTVQIRPGVRNEFNLEEIKKRLQRSVDVKATPYLV
HCCCCCCCCCEEEECCCCHHHEECCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHHH
SFLVEEFRFVLFTDGRAFIHGTNDINVAKRLYTRYIG
HHHHHHCEEEEEECCEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]