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The map label for this gene is argG [H]

Identifier: 118479773

GI number: 118479773

Start: 4434289

End: 4435524

Strand: Reverse

Name: argG [H]

Synonym: BALH_4210

Alternate gene names: 118479773

Gene position: 4435524-4434289 (Counterclockwise)

Preceding gene: 118479776

Following gene: 118479772

Centisome position: 84.37

GC content: 37.94

Gene sequence:

>1236_bases
ATGAATATTTATTCTTTAGGGGGATGCAAAATGGAGAAGAAAAAAGTGGTATTAGCATATTCCGGAGGTCTTGATACTTC
CGTTGCAATTAAATGGTTACAAGAGAAGAATTATGATATTATCGCGCTTTGTTTAGACTTAGGGGAAGGTAAAGACTTAG
CATTTGTAAAAGAAAAGGCACTTTCAGTAGGTGCAATTAAATCATATATGATTGATGTTCAAGAAGAATTTGCAAATGAA
TATGCATTGATGGCGATGCAAGCACACACGTTATACGAAGGGAAATACCCTCTCGTTTCAGCGTTATCACGCCCACTTAT
CGCGAAGAAATTAGTAGAAATTGCAGAACAAGAAGGGGCGACTGCAGTTGCACATGGATGTACAGGGAAAGGGAATGATC
AAGTTCGTTTTGAAGTTTCTATTCAAGCGTTAAATCCTTACTTAGAGGTGATTGCTCCTGTACGTGAATGGAAATGGTCA
CGTGAAGAAGAAATTGCCTATGCAAAAGAAAACAATGTACCAATTCCGATTAATTTAGATAGCCCATTTTCAATCGATCA
AAACTTATGGGGACGCAGTAATGAATGTGGCATTTTAGAAGATCCATGGGCAGCGCCACCAGAAGATGCATATGAGATGA
CATTGGCATTAGAAGATACACCGAATAAACCAGAGTTTGTAGAAATCGGTTTTGAAGCAGGTGTACCAACTACTTTAAAT
GGCACTGCATATCCACTTTCAGAATTAATTAAAACGTTAAATGCACTTGCTGGAAAACATGGCGTTGGACGTATCGATCA
CGTAGAAAATCGTCTTGTTGGTATTAAATCGCGTGAAGTATACGAATGCCCAGCAGCGATGACATTAATTACGGCGCATA
AGGAACTTGAAGATTTAACACTCGTAAAAGAAGTAGCGCATTTTAAACCGATGATTGAGCAGAAAATAACAGAACTTATT
TATAACGGTTTATGGTTCTCACCTTTAAAACAAGCGCTTAACGCTTTCTTACAAGAAACACAAAAGAATGTAACAGGTAC
AGTGCGTGTGAAATTATTTAAAGGCCATGCGATTGTAGAAGGACGTAAATCTGAGTACTCTTTATACGATGAAAAATTAG
CAACATATACTGCTCAGGATGAATTCAATCATGATGCAGCAGTTGGGTTCATTTCATTATTCGGTTTACCGACGAAAGTA
TATAGCCAAGTGAATCAAAAGAAGGTGGAAGCGTGA

Upstream 100 bases:

>100_bases
AAAACAGAAAGAAGTTCGACGAAATTGTTTGAAAAAATTTGAAAATGACTCTTGATACATTTTGTAAAAGGTGTTAAAGT
GTGAATTATTATAAAATAAA

Downstream 100 bases:

>100_bases
GCAAACTTTGGGGCGGACGTTTTACAGAAGAAGCGGAAGCGTGGGTTGAAGAGTTCGGGGCATCCATCTCCTTCGATCAA
CAATTAGTAAATCAAGATAT

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MNIYSLGGCKMEKKKVVLAYSGGLDTSVAIKWLQEKNYDIIALCLDLGEGKDLAFVKEKALSVGAIKSYMIDVQEEFANE
YALMAMQAHTLYEGKYPLVSALSRPLIAKKLVEIAEQEGATAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWS
REEEIAYAKENNVPIPINLDSPFSIDQNLWGRSNECGILEDPWAAPPEDAYEMTLALEDTPNKPEFVEIGFEAGVPTTLN
GTAYPLSELIKTLNALAGKHGVGRIDHVENRLVGIKSREVYECPAAMTLITAHKELEDLTLVKEVAHFKPMIEQKITELI
YNGLWFSPLKQALNAFLQETQKNVTGTVRVKLFKGHAIVEGRKSEYSLYDEKLATYTAQDEFNHDAAVGFISLFGLPTKV
YSQVNQKKVEA

Sequences:

>Translated_411_residues
MNIYSLGGCKMEKKKVVLAYSGGLDTSVAIKWLQEKNYDIIALCLDLGEGKDLAFVKEKALSVGAIKSYMIDVQEEFANE
YALMAMQAHTLYEGKYPLVSALSRPLIAKKLVEIAEQEGATAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWS
REEEIAYAKENNVPIPINLDSPFSIDQNLWGRSNECGILEDPWAAPPEDAYEMTLALEDTPNKPEFVEIGFEAGVPTTLN
GTAYPLSELIKTLNALAGKHGVGRIDHVENRLVGIKSREVYECPAAMTLITAHKELEDLTLVKEVAHFKPMIEQKITELI
YNGLWFSPLKQALNAFLQETQKNVTGTVRVKLFKGHAIVEGRKSEYSLYDEKLATYTAQDEFNHDAAVGFISLFGLPTKV
YSQVNQKKVEA
>Mature_411_residues
MNIYSLGGCKMEKKKVVLAYSGGLDTSVAIKWLQEKNYDIIALCLDLGEGKDLAFVKEKALSVGAIKSYMIDVQEEFANE
YALMAMQAHTLYEGKYPLVSALSRPLIAKKLVEIAEQEGATAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWS
REEEIAYAKENNVPIPINLDSPFSIDQNLWGRSNECGILEDPWAAPPEDAYEMTLALEDTPNKPEFVEIGFEAGVPTTLN
GTAYPLSELIKTLNALAGKHGVGRIDHVENRLVGIKSREVYECPAAMTLITAHKELEDLTLVKEVAHFKPMIEQKITELI
YNGLWFSPLKQALNAFLQETQKNVTGTVRVKLFKGHAIVEGRKSEYSLYDEKLATYTAQDEFNHDAAVGFISLFGLPTKV
YSQVNQKKVEA

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=409, Percent_Identity=43.520782396088, Blast_Score=311, Evalue=6e-85,
Organism=Homo sapiens, GI16950633, Length=409, Percent_Identity=43.520782396088, Blast_Score=311, Evalue=6e-85,
Organism=Escherichia coli, GI1789563, Length=406, Percent_Identity=26.6009852216749, Blast_Score=117, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324514, Length=417, Percent_Identity=38.6091127098321, Blast_Score=284, Evalue=2e-77,
Organism=Drosophila melanogaster, GI21358151, Length=398, Percent_Identity=39.6984924623116, Blast_Score=285, Evalue=4e-77,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 45738; Mature: 45738

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIYSLGGCKMEKKKVVLAYSGGLDTSVAIKWLQEKNYDIIALCLDLGEGKDLAFVKEKA
CCEEECCCCCEECCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHH
LSVGAIKSYMIDVQEEFANEYALMAMQAHTLYEGKYPLVSALSRPLIAKKLVEIAEQEGA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHCCC
TAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWSREEEIAYAKENNVPIPINLD
EEEEECCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCEEEEECC
SPFSIDQNLWGRSNECGILEDPWAAPPEDAYEMTLALEDTPNKPEFVEIGFEAGVPTTLN
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCC
GTAYPLSELIKTLNALAGKHGVGRIDHVENRLVGIKSREVYECPAAMTLITAHKELEDLT
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHEECCCCCCHHHCCHHHHHHHHHHHHHHHH
LVKEVAHFKPMIEQKITELIYNGLWFSPLKQALNAFLQETQKNVTGTVRVKLFKGHAIVE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCEEEC
GRKSEYSLYDEKLATYTAQDEFNHDAAVGFISLFGLPTKVYSQVNQKKVEA
CCCCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIYSLGGCKMEKKKVVLAYSGGLDTSVAIKWLQEKNYDIIALCLDLGEGKDLAFVKEKA
CCEEECCCCCEECCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHH
LSVGAIKSYMIDVQEEFANEYALMAMQAHTLYEGKYPLVSALSRPLIAKKLVEIAEQEGA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHCCC
TAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWSREEEIAYAKENNVPIPINLD
EEEEECCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCEEEEECC
SPFSIDQNLWGRSNECGILEDPWAAPPEDAYEMTLALEDTPNKPEFVEIGFEAGVPTTLN
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCC
GTAYPLSELIKTLNALAGKHGVGRIDHVENRLVGIKSREVYECPAAMTLITAHKELEDLT
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHEECCCCCCHHHCCHHHHHHHHHHHHHHHH
LVKEVAHFKPMIEQKITELIYNGLWFSPLKQALNAFLQETQKNVTGTVRVKLFKGHAIVE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCEEEC
GRKSEYSLYDEKLATYTAQDEFNHDAAVGFISLFGLPTKVYSQVNQKKVEA
CCCCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA