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The map label for this gene is mocR [H]

Identifier: 118478616

GI number: 118478616

Start: 3185041

End: 3186456

Strand: Reverse

Name: mocR [H]

Synonym: BALH_2995

Alternate gene names: 118478616

Gene position: 3186456-3185041 (Counterclockwise)

Preceding gene: 118478618

Following gene: 118478614

Centisome position: 60.61

GC content: 34.32

Gene sequence:

>1416_bases
ATGCTTTGGATACCCATTGACCGGTCATTAGATATACCATTAATTAGACAAGTTTATCAGCAAATACGAGAACAAATTTT
AAACGGGGACTTACAATCAGGAGAAAAACTACCGTCGACACGTGAATTATCTTCTGAGTTGAATGTATCCAGGAATGTGA
TTTTGGAAGCGTATGATCAATTATTGGCTGAAGGATTTTTAGTTGCAAAAAGGGGTGCTGGAACATTTGTTGCTGAAGGA
ACTTTTTTAGAACAACAGAATAAAACACCTTCATTTCATTCTGTGAATTGGAGTGAAGATAAAAATAAAGATGATAACAT
CATCAACTTTCGTTCAGGTATACCAGCACTGGATTTATTTCCGCGTAAGACATGGGCAAAATTGTCTCATACCATATGGA
ATGACATTGCACCTTCTACTTTTGGATACGATATTCCCGAAGGACGTCCGGAATTACGACAGGTTTTATCACGCTATTTA
CTGAAAACAAGAGGTGTTGATTGTCATCCAGAACAAATTGTGATTACATCTGGTGCAACCCAAGCTATGACACTTGTTTC
TAAATTACTTTTATCGCACGATGATACAGTGATAATGGAAGATCCAATCACCAATGATATTCAAACTATATTTAAAACTT
CAGGTGCTCTTCTTTACCCTATACCTGTTGATGAATATGGAATGAAGACATCGTTGCTGCCATTAAATAATTATCCAAAG
TTTATCTTTGTTACTCCGTCCCACCAGTTTCCGTTAGGGGGAACGTTACCAATTCAACGAAGGATTCAATTGATTAACTA
TTCTAGAAGAACAAATTGTTATCTTGTTGAGGATGATTATGACAGTGAATTTAGATATGAAGGACCACCTGTAAGTTCAT
TACAGGGATTGGATTCAGATCGTGTATTATATATTGGTTCGTTTAGTAAAATCTTATCACCAGCCCTTAGAATGGGATAT
TTAATTCTTCCTTCACAACTTATTGAAAAATGTCGCAAGCTAAAATGGTTTTCGGATTTACATACCCCTTCTTTAGAACA
GCTTATCCTTGCCCGTTTTATTGATGAAGGCTATTTGGAACGACATATTATGAAGATGAAGAAAATGTACAAAAAACGAA
GAAACTTCCTTATTCATTGCTTAAAAACAACATTTTCGAATAGGGTTAATGTTTTCGGTTATTCAACAGGCTTACACCTA
ATTGTTGAATTAAATGAATCCCATTTTTCAAAAGAATTACTCGAATGGATCGAACGGTTTGGAGTTAAAGTATATCCTGT
AGAAGATCATACTATAGAAAAAGGAAAACATCATAATCGCATTATTTTAGGTTATGGGCATCTAAAAAATGAAGAAATTA
AAGAAGGTGTGACCAGACTACATAAAGCAATATATAATTTTAAATCCAAAAATTAA

Upstream 100 bases:

>100_bases
TCATATTTACATAAACTTTATCATGGTAAAATGGTTTATATTAGTACCATTTATAATGAATTTTCAAAGTACCAATTTTA
GATAAGGAGTAAATTTCAAT

Downstream 100 bases:

>100_bases
AGCCGAGCCGTCCTTAGCTTAGCATGAGGACAACTCGGCTTAGTTTTCTGTCAGGATCCCATCACTATCCAGCTAAAATT
TTATAATACCTCCAGAACGA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MLWIPIDRSLDIPLIRQVYQQIREQILNGDLQSGEKLPSTRELSSELNVSRNVILEAYDQLLAEGFLVAKRGAGTFVAEG
TFLEQQNKTPSFHSVNWSEDKNKDDNIINFRSGIPALDLFPRKTWAKLSHTIWNDIAPSTFGYDIPEGRPELRQVLSRYL
LKTRGVDCHPEQIVITSGATQAMTLVSKLLLSHDDTVIMEDPITNDIQTIFKTSGALLYPIPVDEYGMKTSLLPLNNYPK
FIFVTPSHQFPLGGTLPIQRRIQLINYSRRTNCYLVEDDYDSEFRYEGPPVSSLQGLDSDRVLYIGSFSKILSPALRMGY
LILPSQLIEKCRKLKWFSDLHTPSLEQLILARFIDEGYLERHIMKMKKMYKKRRNFLIHCLKTTFSNRVNVFGYSTGLHL
IVELNESHFSKELLEWIERFGVKVYPVEDHTIEKGKHHNRIILGYGHLKNEEIKEGVTRLHKAIYNFKSKN

Sequences:

>Translated_471_residues
MLWIPIDRSLDIPLIRQVYQQIREQILNGDLQSGEKLPSTRELSSELNVSRNVILEAYDQLLAEGFLVAKRGAGTFVAEG
TFLEQQNKTPSFHSVNWSEDKNKDDNIINFRSGIPALDLFPRKTWAKLSHTIWNDIAPSTFGYDIPEGRPELRQVLSRYL
LKTRGVDCHPEQIVITSGATQAMTLVSKLLLSHDDTVIMEDPITNDIQTIFKTSGALLYPIPVDEYGMKTSLLPLNNYPK
FIFVTPSHQFPLGGTLPIQRRIQLINYSRRTNCYLVEDDYDSEFRYEGPPVSSLQGLDSDRVLYIGSFSKILSPALRMGY
LILPSQLIEKCRKLKWFSDLHTPSLEQLILARFIDEGYLERHIMKMKKMYKKRRNFLIHCLKTTFSNRVNVFGYSTGLHL
IVELNESHFSKELLEWIERFGVKVYPVEDHTIEKGKHHNRIILGYGHLKNEEIKEGVTRLHKAIYNFKSKN
>Mature_471_residues
MLWIPIDRSLDIPLIRQVYQQIREQILNGDLQSGEKLPSTRELSSELNVSRNVILEAYDQLLAEGFLVAKRGAGTFVAEG
TFLEQQNKTPSFHSVNWSEDKNKDDNIINFRSGIPALDLFPRKTWAKLSHTIWNDIAPSTFGYDIPEGRPELRQVLSRYL
LKTRGVDCHPEQIVITSGATQAMTLVSKLLLSHDDTVIMEDPITNDIQTIFKTSGALLYPIPVDEYGMKTSLLPLNNYPK
FIFVTPSHQFPLGGTLPIQRRIQLINYSRRTNCYLVEDDYDSEFRYEGPPVSSLQGLDSDRVLYIGSFSKILSPALRMGY
LILPSQLIEKCRKLKWFSDLHTPSLEQLILARFIDEGYLERHIMKMKKMYKKRRNFLIHCLKTTFSNRVNVFGYSTGLHL
IVELNESHFSKELLEWIERFGVKVYPVEDHTIEKGKHHNRIILGYGHLKNEEIKEGVTRLHKAIYNFKSKN

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=341, Percent_Identity=23.1671554252199, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI33469970, Length=341, Percent_Identity=23.1671554252199, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1790797, Length=464, Percent_Identity=25.8620689655172, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787710, Length=418, Percent_Identity=27.511961722488, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54359; Mature: 54359

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWIPIDRSLDIPLIRQVYQQIREQILNGDLQSGEKLPSTRELSSELNVSRNVILEAYDQ
CEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHH
LLAEGFLVAKRGAGTFVAEGTFLEQQNKTPSFHSVNWSEDKNKDDNIINFRSGIPALDLF
HHHCCEEEEECCCCCEEECCCEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCC
PRKTWAKLSHTIWNDIAPSTFGYDIPEGRPELRQVLSRYLLKTRGVDCHPEQIVITSGAT
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCH
QAMTLVSKLLLSHDDTVIMEDPITNDIQTIFKTSGALLYPIPVDEYGMKTSLLPLNNYPK
HHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCC
FIFVTPSHQFPLGGTLPIQRRIQLINYSRRTNCYLVEDDYDSEFRYEGPPVSSLQGLDSD
EEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCEECCCCCHHHCCCCCC
RVLYIGSFSKILSPALRMGYLILPSQLIEKCRKLKWFSDLHTPSLEQLILARFIDEGYLE
CEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RHIMKMKKMYKKRRNFLIHCLKTTFSNRVNVFGYSTGLHLIVELNESHFSKELLEWIERF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECHHHHHHHHHHHHHHC
GVKVYPVEDHTIEKGKHHNRIILGYGHLKNEEIKEGVTRLHKAIYNFKSKN
CCEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLWIPIDRSLDIPLIRQVYQQIREQILNGDLQSGEKLPSTRELSSELNVSRNVILEAYDQ
CEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHH
LLAEGFLVAKRGAGTFVAEGTFLEQQNKTPSFHSVNWSEDKNKDDNIINFRSGIPALDLF
HHHCCEEEEECCCCCEEECCCEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCC
PRKTWAKLSHTIWNDIAPSTFGYDIPEGRPELRQVLSRYLLKTRGVDCHPEQIVITSGAT
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCH
QAMTLVSKLLLSHDDTVIMEDPITNDIQTIFKTSGALLYPIPVDEYGMKTSLLPLNNYPK
HHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCC
FIFVTPSHQFPLGGTLPIQRRIQLINYSRRTNCYLVEDDYDSEFRYEGPPVSSLQGLDSD
EEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCEECCCCCHHHCCCCCC
RVLYIGSFSKILSPALRMGYLILPSQLIEKCRKLKWFSDLHTPSLEQLILARFIDEGYLE
CEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RHIMKMKKMYKKRRNFLIHCLKTTFSNRVNVFGYSTGLHLIVELNESHFSKELLEWIERF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECHHHHHHHHHHHHHHC
GVKVYPVEDHTIEKGKHHNRIILGYGHLKNEEIKEGVTRLHKAIYNFKSKN
CCEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]