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The map label for this gene is kipR [H]

Identifier: 118478319

GI number: 118478319

Start: 2846195

End: 2846944

Strand: Reverse

Name: kipR [H]

Synonym: BALH_2682

Alternate gene names: 118478319

Gene position: 2846944-2846195 (Counterclockwise)

Preceding gene: 118478321

Following gene: 118478318

Centisome position: 54.15

GC content: 34.8

Gene sequence:

>750_bases
ATGGTACAGTCCATTGATCGAGCGATAAGTATTATAAAGTTATTAAATTCTACTAATGAAAAAGAGTATTGGGCCATTTC
GGATATAGCGGACAGAACACATCTCCCAGTTAGTACAGTACATAGATTACTTAACTCTCTAATCGAGCATGGGCTAGTTA
CGCAAATTTCAGAGACGAAACAGTACAAAATTGGACCAATGTGGATGGAAATAGGATTACGACAATTGGAGAAGGTAGAC
TACAGATCAGTCGCAAGAGAAGTAATGAAACGATTGGCCTATGAAGTGGAAGAAAGTGTTTATTTGAACATTCCAAATGG
AACACATTCTATTATTATTGAAAGAATGGATAGCCCTTTAAAAATTCGAGTTATTGATAACTTAGGGGAACAGATTCCTC
TTTCAATTGGTGCTGCAAATAAAACAATGCTTGCCAATATGAAACAGAATGAAATGGAATATATTGTTGAGCAACTACTT
TCTGCTTTACCAGAACAAAAGCAAATTCTTCTTAATCAACTAAAGCAAATAAGAAACGAAGGATATGCTGTCAGTTATGG
AGAAAAAACAGAAGGGACAGCTTCAGTAGCTGCACCTATTATTGGATTTAATCATAAAGTAGTAGGAGCATTAAGTGTTG
GGTTAATTAGTCATCGCATTAATGATGATCGACTATCTTTTCTTATTAGTAAGGTAAAACAAGCAGCACATGAAATATCA
ATAAAAATCGGCAGTACATCAGAACTATAG

Upstream 100 bases:

>100_bases
TTAGAAAATTGAATAAACGGATTGATTTCATTTCGAATTTTTGTTAAATTGATAGGTAATTGAGCGTACTAACATATTAC
AAGTCAAGTAGAGGTGAGTT

Downstream 100 bases:

>100_bases
TTTTGATAGCTGTCGTCATTTTTTATTCATATACTGGAATTCATTTTCATAATACGGAAAAATAGGGGGATTTATATGTC
AAAGTGGCAATCAAAAGAAC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MVQSIDRAISIIKLLNSTNEKEYWAISDIADRTHLPVSTVHRLLNSLIEHGLVTQISETKQYKIGPMWMEIGLRQLEKVD
YRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERMDSPLKIRVIDNLGEQIPLSIGAANKTMLANMKQNEMEYIVEQLL
SALPEQKQILLNQLKQIRNEGYAVSYGEKTEGTASVAAPIIGFNHKVVGALSVGLISHRINDDRLSFLISKVKQAAHEIS
IKIGSTSEL

Sequences:

>Translated_249_residues
MVQSIDRAISIIKLLNSTNEKEYWAISDIADRTHLPVSTVHRLLNSLIEHGLVTQISETKQYKIGPMWMEIGLRQLEKVD
YRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERMDSPLKIRVIDNLGEQIPLSIGAANKTMLANMKQNEMEYIVEQLL
SALPEQKQILLNQLKQIRNEGYAVSYGEKTEGTASVAAPIIGFNHKVVGALSVGLISHRINDDRLSFLISKVKQAAHEIS
IKIGSTSEL
>Mature_249_residues
MVQSIDRAISIIKLLNSTNEKEYWAISDIADRTHLPVSTVHRLLNSLIEHGLVTQISETKQYKIGPMWMEIGLRQLEKVD
YRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERMDSPLKIRVIDNLGEQIPLSIGAANKTMLANMKQNEMEYIVEQLL
SALPEQKQILLNQLKQIRNEGYAVSYGEKTEGTASVAAPIIGFNHKVVGALSVGLISHRINDDRLSFLISKVKQAAHEIS
IKIGSTSEL

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=249, Percent_Identity=26.9076305220884, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788131, Length=246, Percent_Identity=26.0162601626016, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786715, Length=247, Percent_Identity=28.7449392712551, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI87082359, Length=252, Percent_Identity=25.7936507936508, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789999, Length=256, Percent_Identity=22.65625, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788581, Length=253, Percent_Identity=25.296442687747, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27973; Mature: 27973

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQSIDRAISIIKLLNSTNEKEYWAISDIADRTHLPVSTVHRLLNSLIEHGLVTQISETK
CCCHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
QYKIGPMWMEIGLRQLEKVDYRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERMDSPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCE
KIRVIDNLGEQIPLSIGAANKTMLANMKQNEMEYIVEQLLSALPEQKQILLNQLKQIRNE
EEEEEHHCCCCCCEEECCCCHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
GYAVSYGEKTEGTASVAAPIIGFNHKVVGALSVGLISHRINDDRLSFLISKVKQAAHEIS
CCEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEE
IKIGSTSEL
EEECCCCCC
>Mature Secondary Structure
MVQSIDRAISIIKLLNSTNEKEYWAISDIADRTHLPVSTVHRLLNSLIEHGLVTQISETK
CCCHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
QYKIGPMWMEIGLRQLEKVDYRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERMDSPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCE
KIRVIDNLGEQIPLSIGAANKTMLANMKQNEMEYIVEQLLSALPEQKQILLNQLKQIRNE
EEEEEHHCCCCCCEEECCCCHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
GYAVSYGEKTEGTASVAAPIIGFNHKVVGALSVGLISHRINDDRLSFLISKVKQAAHEIS
CCEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEE
IKIGSTSEL
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]