Click here to switch to the map view.

The map label for this gene is dhbB [H]

Identifier: 118477772

GI number: 118477772

Start: 2261569

End: 2262462

Strand: Direct

Name: dhbB [H]

Synonym: BALH_2110

Alternate gene names: 118477772

Gene position: 2261569-2262462 (Clockwise)

Preceding gene: 118477771

Following gene: 118477773

Centisome position: 43.02

GC content: 36.91

Gene sequence:

>894_bases
ATGGCTATCCCATCTATTTCAGTATACAAAATGCCAATTGAATCAGAACTACCAAAAAATAAAGTGAACTGGACACCAGA
TCCGAAGCGTGCGGTTCTTCTAATCCATGACATGCAAGAATATTTTCTTGATGCATATAGCGATAAAGAATCACCAAAAG
TAGAACTCATTTCAAATATTAAGGTAATAAGAGAAAAATGTAAGGAACTTGGTATACCAGTTGTTTATACAGCGCAACCA
GGTGGACAAACGTTAGAACAACGAGGATTATTACAAGACTTCTGGGGTGACGGTATTCCTGCTGGACCAGATAAAAAGAA
AATTGTCGATGAACTTTCCCCTAATGATGATGATATATTCTTAACAAAATGGAGATATAGTGCATTTAAAAAGACAAATC
TATTAGAAATTTTAAATGAACAAGGAAGAGATCAACTCATTATTTGTGGTATTTATGCGCATATTGGCTGCCTTTTAACA
GCTTGTGAAGCGTTTATGGATGGTATAGAGCCGTTCTTTGTAGCAGATGCAGTGGCGGATTTTTCATTAGGGCATCATAA
GCAAGCATTGGAGTATGCGTCTAGTAGATGTGCAGTAACGACATCCACCCACTTACTGTTAAAAGATTTACAAAGTGTAA
AAGGTGATAAGAGTGAAGGGATTACTTTACAGGAAGTACATGAACTAGTTGCACAATTACTTCGTGAACCAGTAGAAAGT
ATTGAGACTGATGAAGATTTATTAAATAGAGGACTTGATTCGGTCAGAATTATGAGTTTAGTAGAGAAGTGGCGTCGCGA
AGGAAAAGAAATCACTTTTGCGGATTTAGCAGAGAACCCAACCGTTGTTGATTGGTACCGCTTATTATCTCCGCAAACAG
AACATGTACTTTAA

Upstream 100 bases:

>100_bases
GTGGGAAAAGTGAGCAAAAAAGAATTACGTAAAGTCATTGCGGAAAAACTTGTTACGGTAAAACGATAAGAAAATATAAA
ACTTGGAAGGAAGTGATTAG

Downstream 100 bases:

>100_bases
TATAGACTACATAATAAAGGGGTAGTAAAGAATGCCTAATAGTCAAAAGGTTCGTCATTCATTATCATCTGCGCAGACTG
GTATGTGGTTTGCGCAACAA

Product: isochorismatase

Products: NA

Alternate protein names: 2,3 dihydro-2,3 dihydroxybenzoate synthase; Superoxide-inducible protein 1; SOI1 [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MAIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNIKVIREKCKELGIPVVYTAQP
GGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELSPNDDDIFLTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLT
ACEAFMDGIEPFFVADAVADFSLGHHKQALEYASSRCAVTTSTHLLLKDLQSVKGDKSEGITLQEVHELVAQLLREPVES
IETDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSPQTEHVL

Sequences:

>Translated_297_residues
MAIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNIKVIREKCKELGIPVVYTAQP
GGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELSPNDDDIFLTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLT
ACEAFMDGIEPFFVADAVADFSLGHHKQALEYASSRCAVTTSTHLLLKDLQSVKGDKSEGITLQEVHELVAQLLREPVES
IETDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSPQTEHVL
>Mature_296_residues
AIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNIKVIREKCKELGIPVVYTAQPG
GQTLEQRGLLQDFWGDGIPAGPDKKKIVDELSPNDDDIFLTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLTA
CEAFMDGIEPFFVADAVADFSLGHHKQALEYASSRCAVTTSTHLLLKDLQSVKGDKSEGITLQEVHELVAQLLREPVESI
ETDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSPQTEHVL

Specific function: Required For Production Of 2,3-Dhb. Also Serves As An Aryl Carrier Protein And Plays A Role In Enterobactin Assembly. [C]

COG id: COG1535

COG function: function code Q; Isochorismate hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Escherichia coli, GI1786811, Length=290, Percent_Identity=44.8275862068966, Blast_Score=264, Evalue=6e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009081
- InterPro:   IPR016291
- InterPro:   IPR000868
- InterPro:   IPR006163 [H]

Pfam domain/function: PF00857 Isochorismatase; PF00550 PP-binding [H]

EC number: =3.3.2.1 [H]

Molecular weight: Translated: 33568; Mature: 33437

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNI
CCCCCCEEEECCCHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHH
KVIREKCKELGIPVVYTAQPGGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELSPNDDDIF
HHHHHHHHHCCCCEEEECCCCCHHHHHCCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCEE
LTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLTACEAFMDGIEPFFVADAVAD
EEEHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FSLGHHKQALEYASSRCAVTTSTHLLLKDLQSVKGDKSEGITLQEVHELVAQLLREPVES
HHCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
IETDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSPQTEHVL
CCCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
AIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNI
CCCCCEEEECCCHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHH
KVIREKCKELGIPVVYTAQPGGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELSPNDDDIF
HHHHHHHHHCCCCEEEECCCCCHHHHHCCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCEE
LTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLTACEAFMDGIEPFFVADAVAD
EEEHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FSLGHHKQALEYASSRCAVTTSTHLLLKDLQSVKGDKSEGITLQEVHELVAQLLREPVES
HHCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
IETDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSPQTEHVL
CCCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550523; 9384377; 9298659 [H]