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The map label for this gene is entC [H]

Identifier: 118477770

GI number: 118477770

Start: 2258649

End: 2259908

Strand: Direct

Name: entC [H]

Synonym: BALH_2108

Alternate gene names: 118477770

Gene position: 2258649-2259908 (Clockwise)

Preceding gene: 118477769

Following gene: 118477771

Centisome position: 42.96

GC content: 38.25

Gene sequence:

>1260_bases
ATGTGTCGATGGCGGAGCTACATTAGGAGTTTAATAAAAAATTTAGGGGGCTACTATACTATGAATGAATTTACGGCTGT
AAAGGAACTGTCAGAAAAATTACTAGAAGATTATAAGACTGAATCTTCATTCTTTTTTGCTTCACCAACCCGAACGATAT
TAGCAGAAGGAGAATTTACTACAGTAAAGCATCATGAAATTGAAAGCTTCCCAGAGCTTGTGCAAGCAGTATTACGTAAT
GCAAAACAAGCCGGAAATCCGAATCCTATCGTTGTGGGGGCTTTGCCATTTGATCGTAGAAAAGAAGTCCAACTTATCGT
ACCAGAATATAGCAGGATTTCTGAGCGTTTACAATTGGATACAACAAATCATCTTGAAATAAATAGGAACTTAACATTCG
AAATGACGCCTGTGCCAGATCATGAAGTGTATATGAATGGTGTGAAGCAAGGAATTGAAAAAATAAAGGACGGAGATTTA
AAGAAAATCGTTCTATCTAGATCGTTAGATGTTAAATCTTCTGGAAAAATTGATAAGCAAAAACTTCTTCGAGAATTAGC
AGAGCATAATAAGCACGGTTATACATTTGCGGTGAATTTACCGAAAGATGAAAACGAGAATAGTAAGACGTTAATTGGAG
CTAGTCCTGAATTACTCGTTTCACGTCATGGTATGCAAGTGATTTCTAATCCGTTAGCTGGTTCAAGACCACGTAGTGAT
GATCCAGTAGAAGATAAAAGAAGAGCGGAGGAATTACTTTCTTCTCCAAAAGATTTGCATGAACATGCGGTAGTAGTGGA
AGCAGTTGCTGCTGCGCTTCGCCCATACTGTCATACATTACATGTTCCGGAAAAACCATCTGTTATTCATAGTGAAGCGA
TGTGGCATTTGTCTACTGAAGTGAAAGGTGAACTAAAGAATCCAAATACTAGTTCTTTAGAATTAGCAATTGCTCTTCAT
CCTACGCCAGCAGTTTGCGGAACGCCGATGGAAGAAGCGAGAGAAGCTATTCAACAAATTGAGCCATTTGACCGTGAGTT
CTTTACAGGAATGTTAGGGTGGAGCGATTTAAATGGAGACGGTGAATGGATTGTTACAATTCGTTGTGCTGAAGTACAAG
AAAATACACTCCGTTTATATGCAGGTGCTGGAGTTGTTGCTGAGTCAAAACCAGAAGATGAATTAGCAGAAACATCAGCT
AAGTTTCAAACAATGTTGAAAGCTTTAGGGTTAAATGATAGTTCACTTAATGAAAAGTAG

Upstream 100 bases:

>100_bases
TCGGTATACCGTTACAAAAAATTGCACAGCCTTCAGAAATTGCTGAAGCGGTATTGTTTTTAGCTTCAGATAAAGCGAGT
CATATTACAATGCACAATTT

Downstream 100 bases:

>100_bases
GGGGCAGAAAGAATGTTAACAGGTTATACAAAATGGCCAAAAGAATTTGCCGATCGCTATCGAGAGGAAGGGTGTTGGCT
TGGGGAAACATTTGGCGGAG

Product: isochorismate synthase DhbC

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MCRWRSYIRSLIKNLGGYYTMNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRN
AKQAGNPNPIVVGALPFDRRKEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPDHEVYMNGVKQGIEKIKDGDL
KKIVLSRSLDVKSSGKIDKQKLLRELAEHNKHGYTFAVNLPKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSD
DPVEDKRRAEELLSSPKDLHEHAVVVEAVAAALRPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALH
PTPAVCGTPMEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETSA
KFQTMLKALGLNDSSLNEK

Sequences:

>Translated_419_residues
MCRWRSYIRSLIKNLGGYYTMNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRN
AKQAGNPNPIVVGALPFDRRKEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPDHEVYMNGVKQGIEKIKDGDL
KKIVLSRSLDVKSSGKIDKQKLLRELAEHNKHGYTFAVNLPKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSD
DPVEDKRRAEELLSSPKDLHEHAVVVEAVAAALRPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALH
PTPAVCGTPMEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETSA
KFQTMLKALGLNDSSLNEK
>Mature_419_residues
MCRWRSYIRSLIKNLGGYYTMNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRN
AKQAGNPNPIVVGALPFDRRKEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPDHEVYMNGVKQGIEKIKDGDL
KKIVLSRSLDVKSSGKIDKQKLLRELAEHNKHGYTFAVNLPKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSD
DPVEDKRRAEELLSSPKDLHEHAVVVEAVAAALRPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALH
PTPAVCGTPMEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETSA
KFQTMLKALGLNDSSLNEK

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=377, Percent_Identity=37.9310344827586, Blast_Score=257, Evalue=9e-70,
Organism=Escherichia coli, GI87082077, Length=275, Percent_Identity=29.8181818181818, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788114, Length=277, Percent_Identity=26.7148014440433, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787518, Length=339, Percent_Identity=27.1386430678466, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320935, Length=280, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 47020; Mature: 47020

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRWRSYIRSLIKNLGGYYTMNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFT
CCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCEE
TVKHHEIESFPELVQAVLRNAKQAGNPNPIVVGALPFDRRKEVQLIVPEYSRISERLQLD
EEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEECCCHHHHHHHHCCC
TTNHLEINRNLTFEMTPVPDHEVYMNGVKQGIEKIKDGDLKKIVLSRSLDVKSSGKIDKQ
CCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHH
KLLRELAEHNKHGYTFAVNLPKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSD
HHHHHHHHCCCCCEEEEEECCCCCCCCCCEEECCCHHHHHHHCCHHHHCCCCCCCCCCCC
DPVEDKRRAEELLSSPKDLHEHAVVVEAVAAALRPYCHTLHVPEKPSVIHSEAMWHLSTE
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHH
VKGELKNPNTSSLELAIALHPTPAVCGTPMEEAREAIQQIEPFDREFFTGMLGWSDLNGD
HCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCC
GEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETSAKFQTMLKALGLNDSSLNEK
CCEEEEEEEECCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MCRWRSYIRSLIKNLGGYYTMNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFT
CCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCEE
TVKHHEIESFPELVQAVLRNAKQAGNPNPIVVGALPFDRRKEVQLIVPEYSRISERLQLD
EEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEECCCHHHHHHHHCCC
TTNHLEINRNLTFEMTPVPDHEVYMNGVKQGIEKIKDGDLKKIVLSRSLDVKSSGKIDKQ
CCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHH
KLLRELAEHNKHGYTFAVNLPKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSD
HHHHHHHHCCCCCEEEEEECCCCCCCCCCEEECCCHHHHHHHCCHHHHCCCCCCCCCCCC
DPVEDKRRAEELLSSPKDLHEHAVVVEAVAAALRPYCHTLHVPEKPSVIHSEAMWHLSTE
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHH
VKGELKNPNTSSLELAIALHPTPAVCGTPMEEAREAIQQIEPFDREFFTGMLGWSDLNGD
HCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCC
GEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETSAKFQTMLKALGLNDSSLNEK
CCEEEEEEEECCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550523; 9384377 [H]