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The map label for this gene is adhB [H]

Identifier: 118477653

GI number: 118477653

Start: 2135854

End: 2137065

Strand: Direct

Name: adhB [H]

Synonym: BALH_1985

Alternate gene names: 118477653

Gene position: 2135854-2137065 (Clockwise)

Preceding gene: 118477652

Following gene: 118477654

Centisome position: 40.63

GC content: 35.97

Gene sequence:

>1212_bases
GTGGAGTACTTGCAAGAAGTTGCTGAGTTTCGTATGCCGAAGTCTGTATTATATGGAAGAAATTCTCTTGAAAAGCTGTG
GGAACAATCTAAGAAATTCGGGAAAAGAGCGTTTATAGTTACGGATACAATTATGGAGGATTTAGGATATGTTGAGAGGT
GTATACAACAATTAAATACGAAAGGTATAACTGTTATTACATATAATAAAGTAAATGCTGAGCCTACAAATATACACGTG
TTAGAGGCGTTAACTATTTGTAAAGAAGGAAAGTGTGATTTTATAATCGGTCTTGGTGGTGGAAGTTGTATTGATGCAGC
AAAAGCAGTTGCGGTGTTATATACAAATGGCGGAGAAGTGGAAGATTATGTCCAAAAGGATAGGGAAATAGACAATGATC
CGCTACCACTTATTGCAATCCCAACAACCTCTGGAACTGGATCGGAAGTAACAAGTGTAGCAGTAATTACGAATAAACGA
ACAGATGTAAAAATGATGATGAAGCATCCGAGTTTTACCCCGCAAGTAGCGATTATTGACCCAATTTTAACACGTTCGGT
ACCACCTCACATTACAGCAGCAACAGGGATCGATGCATTATGTCATGCAGTCGAAGCATATATTTCTAAAGTTTCACAAT
CACTTACAGATGTACTCGCTCTTTCAGCAATTGAAAGTATTATGAAATATTTACGTATTGCTTATGAAGATGGAGAGAAT
ATGGAGGCAAGAGAAGCGATGATGATTGCTTCCTTACAAGCTGGAATTGCATTTTCTAATGCATCTGTTACATTAGTTCA
TGGCATGTCGAGACCAGTAGGAGCATTATTTCATGTACCACATGGTATATCGAATGCAATACTATTACCTACAGTTTTAG
AATATACAAAAGGTAGTGCGGTAAAAAGACTAGCGGAAATTGGCCACTGTTTAAATAAAGATTTGTATTCCTATTGTGAT
GAAGAAGTAGCCGACTACACGCTGAGGGAAATAAAAAAACTTTGTTTTGATCTTCGTATTCCAAATTTAAAAGAATACGG
AATTGGTGAAGTTGAATTTGAAAAAGCTATTTCTAAAATGGCGTCAGATGCAATTGAAAGTGGTAGCCCAGAAAATAATC
CACGAGTACCATCCTATGATGAAATTAAACAGTTGTATCGAGAATGTTTTCATTATAAATATGAAGATTCAATAAAAACA
TTAGGGAATTAA

Upstream 100 bases:

>100_bases
AAAACGGTTGCTGTGTTTTTAGTTATTGCATTCTATACAGTAACAGGAATTTATTAAGTCGATATATTATGAACTAAAAT
ATTAATTAGGGTAAGAAGGG

Downstream 100 bases:

>100_bases
TTTCAGAATATTCTTATAAAATTTCCTTGGAAATAGTTAAAACAAGGCTTTATATTTCAAACGTAAAGTCTTGCTTTATT
ATGTATAATATACATAATAA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase II; ADH II [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MEYLQEVAEFRMPKSVLYGRNSLEKLWEQSKKFGKRAFIVTDTIMEDLGYVERCIQQLNTKGITVITYNKVNAEPTNIHV
LEALTICKEGKCDFIIGLGGGSCIDAAKAVAVLYTNGGEVEDYVQKDREIDNDPLPLIAIPTTSGTGSEVTSVAVITNKR
TDVKMMMKHPSFTPQVAIIDPILTRSVPPHITAATGIDALCHAVEAYISKVSQSLTDVLALSAIESIMKYLRIAYEDGEN
MEAREAMMIASLQAGIAFSNASVTLVHGMSRPVGALFHVPHGISNAILLPTVLEYTKGSAVKRLAEIGHCLNKDLYSYCD
EEVADYTLREIKKLCFDLRIPNLKEYGIGEVEFEKAISKMASDAIESGSPENNPRVPSYDEIKQLYRECFHYKYEDSIKT
LGN

Sequences:

>Translated_403_residues
MEYLQEVAEFRMPKSVLYGRNSLEKLWEQSKKFGKRAFIVTDTIMEDLGYVERCIQQLNTKGITVITYNKVNAEPTNIHV
LEALTICKEGKCDFIIGLGGGSCIDAAKAVAVLYTNGGEVEDYVQKDREIDNDPLPLIAIPTTSGTGSEVTSVAVITNKR
TDVKMMMKHPSFTPQVAIIDPILTRSVPPHITAATGIDALCHAVEAYISKVSQSLTDVLALSAIESIMKYLRIAYEDGEN
MEAREAMMIASLQAGIAFSNASVTLVHGMSRPVGALFHVPHGISNAILLPTVLEYTKGSAVKRLAEIGHCLNKDLYSYCD
EEVADYTLREIKKLCFDLRIPNLKEYGIGEVEFEKAISKMASDAIESGSPENNPRVPSYDEIKQLYRECFHYKYEDSIKT
LGN
>Mature_403_residues
MEYLQEVAEFRMPKSVLYGRNSLEKLWEQSKKFGKRAFIVTDTIMEDLGYVERCIQQLNTKGITVITYNKVNAEPTNIHV
LEALTICKEGKCDFIIGLGGGSCIDAAKAVAVLYTNGGEVEDYVQKDREIDNDPLPLIAIPTTSGTGSEVTSVAVITNKR
TDVKMMMKHPSFTPQVAIIDPILTRSVPPHITAATGIDALCHAVEAYISKVSQSLTDVLALSAIESIMKYLRIAYEDGEN
MEAREAMMIASLQAGIAFSNASVTLVHGMSRPVGALFHVPHGISNAILLPTVLEYTKGSAVKRLAEIGHCLNKDLYSYCD
EEVADYTLREIKKLCFDLRIPNLKEYGIGEVEFEKAISKMASDAIESGSPENNPRVPSYDEIKQLYRECFHYKYEDSIKT
LGN

Specific function: May Act On The Acetaldehyde Produced From The Degradation Of Ethanolamine. [C]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=381, Percent_Identity=30.4461942257218, Blast_Score=150, Evalue=3e-36,
Organism=Escherichia coli, GI48994951, Length=380, Percent_Identity=35.5263157894737, Blast_Score=234, Evalue=5e-63,
Organism=Escherichia coli, GI87082107, Length=395, Percent_Identity=36.7088607594937, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789163, Length=380, Percent_Identity=32.6315789473684, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1787493, Length=411, Percent_Identity=33.3333333333333, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI1789386, Length=357, Percent_Identity=23.249299719888, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17537053, Length=422, Percent_Identity=27.9620853080569, Blast_Score=138, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6321181, Length=393, Percent_Identity=35.6234096692112, Blast_Score=229, Evalue=8e-61,
Organism=Drosophila melanogaster, GI24657991, Length=353, Percent_Identity=30.3116147308782, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 44595; Mature: 44595

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYLQEVAEFRMPKSVLYGRNSLEKLWEQSKKFGKRAFIVTDTIMEDLGYVERCIQQLNT
CHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCC
KGITVITYNKVNAEPTNIHVLEALTICKEGKCDFIIGLGGGSCIDAAKAVAVLYTNGGEV
CCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHEEEEEEECCCCH
EDYVQKDREIDNDPLPLIAIPTTSGTGSEVTSVAVITNKRTDVKMMMKHPSFTPQVAIID
HHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCEEEEC
PILTRSVPPHITAATGIDALCHAVEAYISKVSQSLTDVLALSAIESIMKYLRIAYEDGEN
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MEAREAMMIASLQAGIAFSNASVTLVHGMSRPVGALFHVPHGISNAILLPTVLEYTKGSA
CHHHHHHHHHHHHHCEEECCCCEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCHH
VKRLAEIGHCLNKDLYSYCDEEVADYTLREIKKLCFDLRIPNLKEYGIGEVEFEKAISKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHH
ASDAIESGSPENNPRVPSYDEIKQLYRECFHYKYEDSIKTLGN
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MEYLQEVAEFRMPKSVLYGRNSLEKLWEQSKKFGKRAFIVTDTIMEDLGYVERCIQQLNT
CHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCC
KGITVITYNKVNAEPTNIHVLEALTICKEGKCDFIIGLGGGSCIDAAKAVAVLYTNGGEV
CCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHEEEEEEECCCCH
EDYVQKDREIDNDPLPLIAIPTTSGTGSEVTSVAVITNKRTDVKMMMKHPSFTPQVAIID
HHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCEEEEC
PILTRSVPPHITAATGIDALCHAVEAYISKVSQSLTDVLALSAIESIMKYLRIAYEDGEN
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MEAREAMMIASLQAGIAFSNASVTLVHGMSRPVGALFHVPHGISNAILLPTVLEYTKGSA
CHHHHHHHHHHHHHCEEECCCCEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCHH
VKRLAEIGHCLNKDLYSYCDEEVADYTLREIKKLCFDLRIPNLKEYGIGEVEFEKAISKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHH
ASDAIESGSPENNPRVPSYDEIKQLYRECFHYKYEDSIKTLGN
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3584063; 2308827; 2935393 [H]