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The map label for this gene is mhpF [C]

Identifier: 118477518

GI number: 118477518

Start: 1995120

End: 1996019

Strand: Direct

Name: mhpF [C]

Synonym: BALH_1843

Alternate gene names: 118477518

Gene position: 1995120-1996019 (Clockwise)

Preceding gene: 118477517

Following gene: 118477519

Centisome position: 37.95

GC content: 37.67

Gene sequence:

>900_bases
GTGCAGAAAGTAAAGGCGGCCATAATTGGATCAGGTAATATTGGTACGGATTTAATGTATAAATTAAGAAAAAGTGAAGT
CATAGACCTCAATGCCATGATTGGAATAGATGTAGAATCGGATGGTTTAAAGAGGGCGAAAGAAGCCGGATACGAGGTTT
TTGATAATGGAATACAGGCAATTATTGATAATCCCAGTTTAGCTGATATTGTATTTGATGCAACTTCAGCTAAAGCACAT
AGATATCATGCGAAAACGTTAGAAGAGCTTGAAAAAATAGTAATTGACTTAACACCGGCTGCATATGGGCCATTTGTTTG
TCCTGCTATTCGAAATAATAATTTTTTAGATAAGCAAAACGTTAATATGATTACGTGCGGGGGACAAGCAACAATCCCGA
TTGTTCATGCTATTAATGGGGTGGCGAATGTTACATATGCAGAGATCGTTGCTACAATTTCCAGTTTAAGTGCAGGTCCA
GGTACAAGGGCAAATATTGATGAATTTACAATTACGACAAAGCGTGGAATTGAAGAAGTTGGTGGGGCTGATAAGGGGAA
GGCGATAATTATATTAAACCCTGCAGAGCCACCTATATTAATGAGAGATACGATTTATTGTGAAGTTAAGGATATGGATG
AGGTTTCTATCTATGAAGCAATTCATAAGATGGTAGAACGGGTTAGGACGTATGTTCCTGGTTACTCTTTGAAACAAGAG
CCAATGTTTGATGGGAATCGTGTAACTGTATTTTTAGAAGTTGAAGGAGCTGGAGATTATTTTCCTCCTTATGCCGGTAA
TTTAGATATTATGACAGCTGCAGCATTAAAAGTAGGTGAAGAATTTGCAACGCAAATCATCTCAGAGAAGAAAAGAGGTG
TAATGAATGAGGCGAAATAG

Upstream 100 bases:

>100_bases
AGTGAATAGTAAAGATAGCATTCAAGCTGACTTCGGTTCACTAGGATCGGTTTCAGTTACATTCATATAGGTTAAAATGC
TATGAAAAGGTGGGATAGAT

Downstream 100 bases:

>100_bases
TGAAAGACCAGTGAGAATAACGGAAGTTTGTTTACGTGATGGAAGTCATGTAATGAAACATCAATTTACAGAAGAGCAAG
TTCGATTTGTAACAAGGGCA

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MQKVKAAIIGSGNIGTDLMYKLRKSEVIDLNAMIGIDVESDGLKRAKEAGYEVFDNGIQAIIDNPSLADIVFDATSAKAH
RYHAKTLEELEKIVIDLTPAAYGPFVCPAIRNNNFLDKQNVNMITCGGQATIPIVHAINGVANVTYAEIVATISSLSAGP
GTRANIDEFTITTKRGIEEVGGADKGKAIIILNPAEPPILMRDTIYCEVKDMDEVSIYEAIHKMVERVRTYVPGYSLKQE
PMFDGNRVTVFLEVEGAGDYFPPYAGNLDIMTAAALKVGEEFATQIISEKKRGVMNEAK

Sequences:

>Translated_299_residues
MQKVKAAIIGSGNIGTDLMYKLRKSEVIDLNAMIGIDVESDGLKRAKEAGYEVFDNGIQAIIDNPSLADIVFDATSAKAH
RYHAKTLEELEKIVIDLTPAAYGPFVCPAIRNNNFLDKQNVNMITCGGQATIPIVHAINGVANVTYAEIVATISSLSAGP
GTRANIDEFTITTKRGIEEVGGADKGKAIIILNPAEPPILMRDTIYCEVKDMDEVSIYEAIHKMVERVRTYVPGYSLKQE
PMFDGNRVTVFLEVEGAGDYFPPYAGNLDIMTAAALKVGEEFATQIISEKKRGVMNEAK
>Mature_299_residues
MQKVKAAIIGSGNIGTDLMYKLRKSEVIDLNAMIGIDVESDGLKRAKEAGYEVFDNGIQAIIDNPSLADIVFDATSAKAH
RYHAKTLEELEKIVIDLTPAAYGPFVCPAIRNNNFLDKQNVNMITCGGQATIPIVHAINGVANVTYAEIVATISSLSAGP
GTRANIDEFTITTKRGIEEVGGADKGKAIIILNPAEPPILMRDTIYCEVKDMDEVSIYEAIHKMVERVRTYVPGYSLKQE
PMFDGNRVTVFLEVEGAGDYFPPYAGNLDIMTAAALKVGEEFATQIISEKKRGVMNEAK

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=308, Percent_Identity=51.9480519480519, Blast_Score=296, Evalue=9e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH_BACAH (A0RD69)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_894669.1
- ProteinModelPortal:   A0RD69
- SMR:   A0RD69
- STRING:   A0RD69
- EnsemblBacteria:   EBBACT00000068498
- GeneID:   4545493
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_1843
- NMPDR:   fig|412694.5.peg.1829
- eggNOG:   COG4569
- GeneTree:   EBGT00050000005163
- HOGENOM:   HBG300125
- OMA:   HVKNDAF
- ProtClustDB:   PRK08300
- BioCyc:   BTHU412694:BALH_1843-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 32520; Mature: 32520

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: BINDING 267-267

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVKAAIIGSGNIGTDLMYKLRKSEVIDLNAMIGIDVESDGLKRAKEAGYEVFDNGIQA
CCCEEEEEEECCCCCHHHHHHHHHCCEEEEEEEEEEEECCCHHHHHHHCCHHHHHCCCEE
IIDNPSLADIVFDATSAKAHRYHAKTLEELEKIVIDLTPAAYGPFVCPAIRNNNFLDKQN
EECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHEECCCCCCCCEECCEECCCCCCCCCC
VNMITCGGQATIPIVHAINGVANVTYAEIVATISSLSAGPGTRANIDEFTITTKRGIEEV
CCEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHCHHHH
GGADKGKAIIILNPAEPPILMRDTIYCEVKDMDEVSIYEAIHKMVERVRTYVPGYSLKQE
CCCCCCCEEEEECCCCCCEEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
PMFDGNRVTVFLEVEGAGDYFPPYAGNLDIMTAAALKVGEEFATQIISEKKRGVMNEAK
CCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQKVKAAIIGSGNIGTDLMYKLRKSEVIDLNAMIGIDVESDGLKRAKEAGYEVFDNGIQA
CCCEEEEEEECCCCCHHHHHHHHHCCEEEEEEEEEEEECCCHHHHHHHCCHHHHHCCCEE
IIDNPSLADIVFDATSAKAHRYHAKTLEELEKIVIDLTPAAYGPFVCPAIRNNNFLDKQN
EECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHEECCCCCCCCEECCEECCCCCCCCCC
VNMITCGGQATIPIVHAINGVANVTYAEIVATISSLSAGPGTRANIDEFTITTKRGIEEV
CCEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHCHHHH
GGADKGKAIIILNPAEPPILMRDTIYCEVKDMDEVSIYEAIHKMVERVRTYVPGYSLKQE
CCCCCCCEEEEECCCCCCEEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
PMFDGNRVTVFLEVEGAGDYFPPYAGNLDIMTAAALKVGEEFATQIISEKKRGVMNEAK
CCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA