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The map label for this gene is yccK [H]

Identifier: 118477452

GI number: 118477452

Start: 1931496

End: 1932431

Strand: Direct

Name: yccK [H]

Synonym: BALH_1773

Alternate gene names: 118477452

Gene position: 1931496-1932431 (Clockwise)

Preceding gene: 118477450

Following gene: 118477453

Centisome position: 36.74

GC content: 34.29

Gene sequence:

>936_bases
ATGAAGTATACAAAATTGCAAAAGGCAGGACTACATATTTCAAAGTTGGGGTTAGGAACAAATGCTGTAGGGGGGCATAA
TTTATATGCTGATGTGAATGAGGAAGAAGGAAAACAATTAATAGAAGAAGCTATGGGGCAAGGGATTACATTTTTTGATA
CAGCAGATTCATACGGTTTCGGTAGATCAGAGGAATTAGTAGGAGAAGTATTGAAAGGAAAACGCCACGAAATTGTACTT
GCTACAAAAGGTGGAATACAGCCGCTATTAAATGGAGAGGTGTATATAAATAATGAACGAAACTATTTAAGAAATGCTGT
GGAAAATAGCTTACGAAGATTACAAACTGATTATATTGATTTATATTATTTACATTTTACAAATCCAGAAACAAGTTATA
TAGATTCAATTGGAGAACTTACTCGCCTAAAAGAAGAAGGGAAAATTCGTTCAATTGGAATATCTAACGTAAACGTAGAG
CAATTAAAAGAAGCGAATCAGCACGGACACATAGATGTTGTACAATCACCGTATAATATGTTGGATCGTACTGCAGGGGA
AGAACTTTTGCCATATTGTATAGAATCAGGTATTTCATTTATCCCTTACGGGCCTCTTGCTTTTGGGATATTAGGTGGTA
AATATACAGAAGATTTTAAATTGAACGAAGGAGACTGGCGTCAAAGTGTAAATCTATTTGAAGAAAATACATATAAGAGT
AACTTTAAAAAAGTTGAGAAGTTAAAAGGCGTAGCTAAAGAAGAGGCTGTCGAAGTATCGCATTTAGCATTAGCATGGCT
ATTAAATAAAAAAGGAATTGATACTGTTATTCCTGGTGGGAAAAGAGCGGAGCAAATAAGAGAAAGTGTAAGAGCTGTGG
AAGTTTCATTGAATGAAAATGTCATGAAAGAGATTGAATCTATTTTAGAAGATTAG

Upstream 100 bases:

>100_bases
CCTGCTTGTATAAGTTACTATATTTGCACTATAACATATAAAGTGGTATATTTCTATTGTTCGAATATAATCGAACAATA
GAAATATAGGGGGAGAAAAA

Downstream 100 bases:

>100_bases
TTGAAGGAGGGATAGTTCCCTTTTTTTATATAAAAGGAGAAGGTTTAAATGAAAAGAGTACTAGCTGTATTCTTTACAAT
CATGTTTATGATCGGTACAG

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEEEGKQLIEEAMGQGITFFDTADSYGFGRSEELVGEVLKGKRHEIVL
ATKGGIQPLLNGEVYINNERNYLRNAVENSLRRLQTDYIDLYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVE
QLKEANQHGHIDVVQSPYNMLDRTAGEELLPYCIESGISFIPYGPLAFGILGGKYTEDFKLNEGDWRQSVNLFEENTYKS
NFKKVEKLKGVAKEEAVEVSHLALAWLLNKKGIDTVIPGGKRAEQIRESVRAVEVSLNENVMKEIESILED

Sequences:

>Translated_311_residues
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEEEGKQLIEEAMGQGITFFDTADSYGFGRSEELVGEVLKGKRHEIVL
ATKGGIQPLLNGEVYINNERNYLRNAVENSLRRLQTDYIDLYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVE
QLKEANQHGHIDVVQSPYNMLDRTAGEELLPYCIESGISFIPYGPLAFGILGGKYTEDFKLNEGDWRQSVNLFEENTYKS
NFKKVEKLKGVAKEEAVEVSHLALAWLLNKKGIDTVIPGGKRAEQIRESVRAVEVSLNENVMKEIESILED
>Mature_311_residues
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEEEGKQLIEEAMGQGITFFDTADSYGFGRSEELVGEVLKGKRHEIVL
ATKGGIQPLLNGEVYINNERNYLRNAVENSLRRLQTDYIDLYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVE
QLKEANQHGHIDVVQSPYNMLDRTAGEELLPYCIESGISFIPYGPLAFGILGGKYTEDFKLNEGDWRQSVNLFEENTYKS
NFKKVEKLKGVAKEEAVEVSHLALAWLLNKKGIDTVIPGGKRAEQIRESVRAVEVSLNENVMKEIESILED

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=330, Percent_Identity=29.0909090909091, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI4504825, Length=328, Percent_Identity=28.9634146341463, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI27436964, Length=332, Percent_Identity=28.3132530120482, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI27436962, Length=332, Percent_Identity=28.0120481927711, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI27436966, Length=332, Percent_Identity=27.710843373494, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI27436971, Length=330, Percent_Identity=28.1818181818182, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI41327764, Length=276, Percent_Identity=30.0724637681159, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI223718702, Length=276, Percent_Identity=27.8985507246377, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI41152114, Length=217, Percent_Identity=29.9539170506912, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1788070, Length=327, Percent_Identity=33.9449541284404, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI87081735, Length=319, Percent_Identity=33.5423197492163, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=27.6162790697674, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=28.1818181818182, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788081, Length=254, Percent_Identity=25.9842519685039, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787674, Length=303, Percent_Identity=24.0924092409241, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082198, Length=163, Percent_Identity=31.2883435582822, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994888, Length=269, Percent_Identity=25.6505576208178, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561298, Length=318, Percent_Identity=24.8427672955975, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI212645785, Length=329, Percent_Identity=24.0121580547112, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564128, Length=326, Percent_Identity=23.9263803680982, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71998625, Length=211, Percent_Identity=29.8578199052133, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=335, Percent_Identity=27.7611940298507, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6323998, Length=325, Percent_Identity=26.1538461538462, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=293, Percent_Identity=27.3037542662116, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=321, Percent_Identity=26.1682242990654, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=222, Percent_Identity=25.6756756756757, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321052, Length=149, Percent_Identity=30.8724832214765, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640980, Length=350, Percent_Identity=23.7142857142857, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45549126, Length=350, Percent_Identity=23.7142857142857, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24646159, Length=225, Percent_Identity=32.4444444444444, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646155, Length=310, Percent_Identity=28.0645161290323, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34902; Mature: 34902

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEEEGKQLIEEAMGQGITFFDTADSYGF
CCCCHHHHCCCEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCC
GRSEELVGEVLKGKRHEIVLATKGGIQPLLNGEVYINNERNYLRNAVENSLRRLQTDYID
CCCHHHHHHHHCCCCCEEEEEECCCCCEEECCEEEECCCHHHHHHHHHHHHHHHHHCCEE
LYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVEQLKEANQHGHIDVVQSPYNM
EEEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCCCCCCEEEECCCHHH
LDRTAGEELLPYCIESGISFIPYGPLAFGILGGKYTEDFKLNEGDWRQSVNLFEENTYKS
HHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NFKKVEKLKGVAKEEAVEVSHLALAWLLNKKGIDTVIPGGKRAEQIRESVRAVEVSLNEN
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
VMKEIESILED
HHHHHHHHHCC
>Mature Secondary Structure
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEEEGKQLIEEAMGQGITFFDTADSYGF
CCCCHHHHCCCEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCC
GRSEELVGEVLKGKRHEIVLATKGGIQPLLNGEVYINNERNYLRNAVENSLRRLQTDYID
CCCHHHHHHHHCCCCCEEEEEECCCCCEEECCEEEECCCHHHHHHHHHHHHHHHHHCCEE
LYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVEQLKEANQHGHIDVVQSPYNM
EEEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCCCCCCEEEECCCHHH
LDRTAGEELLPYCIESGISFIPYGPLAFGILGGKYTEDFKLNEGDWRQSVNLFEENTYKS
HHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NFKKVEKLKGVAKEEAVEVSHLALAWLLNKKGIDTVIPGGKRAEQIRESVRAVEVSLNEN
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
VMKEIESILED
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]