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The map label for this gene is isp [H]

Identifier: 118477450

GI number: 118477450

Start: 1930089

End: 1931039

Strand: Direct

Name: isp [H]

Synonym: BALH_1771

Alternate gene names: 118477450

Gene position: 1930089-1931039 (Clockwise)

Preceding gene: 118477449

Following gene: 118477452

Centisome position: 36.71

GC content: 38.38

Gene sequence:

>951_bases
ATGAACAGTAGTACAGCGAATAAACAAAAAGGTATACAATTGATTCCTTTTACAGTAGATAAGGTAGTTGAACAAGTAAA
TGAAATTCCACCAGGTGTACAACTCATTCATGCTCCACAAGTATGGGAGAAGAGTGCAAAAGGAAAAGATATTGTTGTTG
CCGTATTAGATACAGGGTGTGATATGAATCATATAGATTTAAAGGATCGTATTATCGGCGGAAGAAATTTCACGAAAGAT
TACGAAGGAGATCCAAATATTTATCTTGATAATAACGGACACGGTACTCATGTAGCGGGGACAATTGCAGCGACTGAAAA
TGGAGTTGGTGTTTTAGGAGTCGCACCGCTCGCTAAAATGTTAGTGTTAAAGGTTTTAGCAGGAGATGGTTCTGGAAGTT
ATGAGCAAATTATTGAGGCGATACATTATGCTGTAAATTGGAGAGGGCCTAATAAAGAAAGAGTTAGAGTTATTTCCATG
TCACTTGGTGGCCCGCAAGATGTTCCAGAATTACATGAAGCAATTCAAAATGCGGTAAAGCAAGATGTTCTCGTCGTATG
TGCTGCTGGGAATAATGGAGATTGTAATGATAACACGGAGGAACTAGATTTTCCAGGCGCATACTCAGAAGTAATTGAAG
TCGGCGCTGTCAATTTAGAAAGGAAAATCGCGTGTTTTAGTAATTCAAATCAAGAAATTGATTTAGTAGCACCAGGCGAT
GAAATATTATCTACGTATCCTGAAGGGAAATATGCGGTATTAAGTGGTACTTCTATGGCCACACCGCATGTTGCTGGGGC
ACTGGCATTGCTCATAAAGCAGTGTGAAAGGGAATATGGTAGAAAGTTATCAGAACCAGAAATATATGCACAGCTTATTA
AAAGAACTGTACCTTTAGGGTATGAACGTACATCTGAAGGGAATGGATTAATAGATTTATTGAAAGAATAA

Upstream 100 bases:

>100_bases
TTTTAAGGAAGGAAAACGAAACAACTAAAACGAATGTTACATGTAAGCATTTTCAAAAGTGGTCTGAAATGAAAATAATA
TATTTTCAGGAGGGATTACG

Downstream 100 bases:

>100_bases
CAATTACTAAAAAACATCTCATATTTTTATGAGATGTTTTTTAGTATGGTTCTGTCGCATGTATTATGACATCCAATAAA
CCGGGGAATCTAGCATTTAA

Product: IspA peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNSSTANKQKGIQLIPFTVDKVVEQVNEIPPGVQLIHAPQVWEKSAKGKDIVVAVLDTGCDMNHIDLKDRIIGGRNFTKD
YEGDPNIYLDNNGHGTHVAGTIAATENGVGVLGVAPLAKMLVLKVLAGDGSGSYEQIIEAIHYAVNWRGPNKERVRVISM
SLGGPQDVPELHEAIQNAVKQDVLVVCAAGNNGDCNDNTEELDFPGAYSEVIEVGAVNLERKIACFSNSNQEIDLVAPGD
EILSTYPEGKYAVLSGTSMATPHVAGALALLIKQCEREYGRKLSEPEIYAQLIKRTVPLGYERTSEGNGLIDLLKE

Sequences:

>Translated_316_residues
MNSSTANKQKGIQLIPFTVDKVVEQVNEIPPGVQLIHAPQVWEKSAKGKDIVVAVLDTGCDMNHIDLKDRIIGGRNFTKD
YEGDPNIYLDNNGHGTHVAGTIAATENGVGVLGVAPLAKMLVLKVLAGDGSGSYEQIIEAIHYAVNWRGPNKERVRVISM
SLGGPQDVPELHEAIQNAVKQDVLVVCAAGNNGDCNDNTEELDFPGAYSEVIEVGAVNLERKIACFSNSNQEIDLVAPGD
EILSTYPEGKYAVLSGTSMATPHVAGALALLIKQCEREYGRKLSEPEIYAQLIKRTVPLGYERTSEGNGLIDLLKE
>Mature_316_residues
MNSSTANKQKGIQLIPFTVDKVVEQVNEIPPGVQLIHAPQVWEKSAKGKDIVVAVLDTGCDMNHIDLKDRIIGGRNFTKD
YEGDPNIYLDNNGHGTHVAGTIAATENGVGVLGVAPLAKMLVLKVLAGDGSGSYEQIIEAIHYAVNWRGPNKERVRVISM
SLGGPQDVPELHEAIQNAVKQDVLVVCAAGNNGDCNDNTEELDFPGAYSEVIEVGAVNLERKIACFSNSNQEIDLVAPGD
EILSTYPEGKYAVLSGTSMATPHVAGALALLIKQCEREYGRKLSEPEIYAQLIKRTVPLGYERTSEGNGLIDLLKE

Specific function: Involved in the generation of beta- and alpha-amylases from the large amylase precursor [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=299, Percent_Identity=28.7625418060201, Blast_Score=98, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6320775, Length=233, Percent_Identity=36.9098712446352, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6324576, Length=235, Percent_Identity=35.3191489361702, Blast_Score=105, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6319893, Length=261, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI45550681, Length=252, Percent_Identity=29.7619047619048, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 34057; Mature: 34057

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSTANKQKGIQLIPFTVDKVVEQVNEIPPGVQLIHAPQVWEKSAKGKDIVVAVLDTGC
CCCCCCCHHCCCEEECCCHHHHHHHHHHCCCCCEEEECCHHHHHCCCCCEEEEEEEECCC
DMNHIDLKDRIIGGRNFTKDYEGDPNIYLDNNGHGTHVAGTIAATENGVGVLGVAPLAKM
CCCCCCHHHHEECCCCCCCCCCCCCCEEECCCCCCCEEEEEEEECCCCCEEEEHHHHHHH
LVLKVLAGDGSGSYEQIIEAIHYAVNWRGPNKERVRVISMSLGGPQDVPELHEAIQNAVK
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHC
QDVLVVCAAGNNGDCNDNTEELDFPGAYSEVIEVGAVNLERKIACFSNSNQEIDLVAPGD
CCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHEEEEECCCCCEEEEECCCH
EILSTYPEGKYAVLSGTSMATPHVAGALALLIKQCEREYGRKLSEPEIYAQLIKRTVPLG
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
YERTSEGNGLIDLLKE
CCCCCCCCCHHHHHCC
>Mature Secondary Structure
MNSSTANKQKGIQLIPFTVDKVVEQVNEIPPGVQLIHAPQVWEKSAKGKDIVVAVLDTGC
CCCCCCCHHCCCEEECCCHHHHHHHHHHCCCCCEEEECCHHHHHCCCCCEEEEEEEECCC
DMNHIDLKDRIIGGRNFTKDYEGDPNIYLDNNGHGTHVAGTIAATENGVGVLGVAPLAKM
CCCCCCHHHHEECCCCCCCCCCCCCCEEECCCCCCCEEEEEEEECCCCCEEEEHHHHHHH
LVLKVLAGDGSGSYEQIIEAIHYAVNWRGPNKERVRVISMSLGGPQDVPELHEAIQNAVK
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHC
QDVLVVCAAGNNGDCNDNTEELDFPGAYSEVIEVGAVNLERKIACFSNSNQEIDLVAPGD
CCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHEEEEECCCCCEEEEECCCH
EILSTYPEGKYAVLSGTSMATPHVAGALALLIKQCEREYGRKLSEPEIYAQLIKRTVPLG
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
YERTSEGNGLIDLLKE
CCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1834632 [H]