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The map label for this gene is phoP [H]

Identifier: 118477427

GI number: 118477427

Start: 1905312

End: 1906010

Strand: Direct

Name: phoP [H]

Synonym: BALH_1747

Alternate gene names: 118477427

Gene position: 1905312-1906010 (Clockwise)

Preceding gene: 118477426

Following gene: 118477428

Centisome position: 36.24

GC content: 34.19

Gene sequence:

>699_bases
GTGGAAATGATGCCAACAATTTTAGTTATAGAAGATGAAATACCTATTCGTAGTTTTATTGTCCTAAATTTGAAACGTGC
TGGATTTTATGTATTAGAAGCCAGTACTGGAGAAGAAGCGTTACAAATTTTATGTGAACATACTGTAGATGTAGCTTTAC
TTGATGTAATGTTACCGGGAATGGATGGTTTTCAAGTTTGTAAAGCAATCCGGGAAGAAAATAAAAAAATAGGTATTATT
ATGTTAACCGCGCGCGTACAAAATGAAGATAAAGTACAAGGGTTAGGAATTGGTGCAGATGATTATATCGCAAAGCCGTT
TAGTCCTGTGGAACTAACTGCACGTATACAATCGTTACTAAGAAGAATAGAAGTACATGATGAAAAAGCACATACCATCA
CATCTGGTCCGTTTTTATTAAATATAATAGAAGAAAGATTATATAAAAGTGGACAACTAGTCGATTTAACCCCTACAGAG
TATATGATATTACAGTATTTAATGAATCAGGCTTCAAAACCGGTTTCACGTGATGAAATTTTAAATATGATTTGGGGAAC
GAATTATGTAGGAGAGACGAAAGTAGTAGATGTAAATATGAGGCGGTTACGTCAAAAGATAGAGTGTAATCCATCAGAAC
CTGAATTTATTCTTACTGTGTGGGGAAAAGGATATGTGTGGAAGGAAAGTATAAGATGA

Upstream 100 bases:

>100_bases
AAAACGGCTTCTCACGTATATGCTGTACCGAAACAACCACATTTTGAAAAAGTGAAAATATATGTAAAGCCGCTAGCGGA
TTATCAACAAGAGTAGGGAG

Downstream 100 bases:

>100_bases
AAAGAAAAGTGACTTTATATTTTATGACGGTCATTATACTTATGCTTGTATTATTTGAAGTCGTATTTTCAGTCTCCGTT
TATCGATATTATTATAACGG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MEMMPTILVIEDEIPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDGFQVCKAIREENKKIGII
MLTARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRIEVHDEKAHTITSGPFLLNIIEERLYKSGQLVDLTPTE
YMILQYLMNQASKPVSRDEILNMIWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR

Sequences:

>Translated_232_residues
MEMMPTILVIEDEIPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDGFQVCKAIREENKKIGII
MLTARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRIEVHDEKAHTITSGPFLLNIIEERLYKSGQLVDLTPTE
YMILQYLMNQASKPVSRDEILNMIWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR
>Mature_232_residues
MEMMPTILVIEDEIPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPGMDGFQVCKAIREENKKIGII
MLTARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLLRRIEVHDEKAHTITSGPFLLNIIEERLYKSGQLVDLTPTE
YMILQYLMNQASKPVSRDEILNMIWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=35.8407079646018, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=40, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=35.8078602620087, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=33.0434782608696, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=34.3478260869565, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=34.2465753424658, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=34.2342342342342, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=32.2727272727273, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=31.8385650224215, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=33.0316742081448, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=29.7872340425532, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=31.8777292576419, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=28.3898305084746, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788550, Length=159, Percent_Identity=28.9308176100629, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=29.0076335877863, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=132, Percent_Identity=31.0606060606061, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788713, Length=103, Percent_Identity=32.0388349514563, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26456; Mature: 26456

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMMPTILVIEDEIPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPG
CCCCCEEEEEECCCCCEEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
MDGFQVCKAIREENKKIGIIMLTARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLL
CCHHHHHHHHHHCCCEEEEEEEEEEECCCCCCEEECCCCCHHHCCCCCCHHHHHHHHHHH
RRIEVHDEKAHTITSGPFLLNIIEERLYKSGQLVDLTPTEYMILQYLMNQASKPVSRDEI
HHHHCCCCCCCEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHH
LNMIWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR
HHHHHCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCCC
>Mature Secondary Structure
MEMMPTILVIEDEIPIRSFIVLNLKRAGFYVLEASTGEEALQILCEHTVDVALLDVMLPG
CCCCCEEEEEECCCCCEEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
MDGFQVCKAIREENKKIGIIMLTARVQNEDKVQGLGIGADDYIAKPFSPVELTARIQSLL
CCHHHHHHHHHHCCCEEEEEEEEEEECCCCCCEEECCCCCHHHCCCCCCHHHHHHHHHHH
RRIEVHDEKAHTITSGPFLLNIIEERLYKSGQLVDLTPTEYMILQYLMNQASKPVSRDEI
HHHHCCCCCCCEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHH
LNMIWGTNYVGETKVVDVNMRRLRQKIECNPSEPEFILTVWGKGYVWKESIR
HHHHHCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]