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The map label for this gene is yvrG [H]

Identifier: 118477353

GI number: 118477353

Start: 1821837

End: 1823273

Strand: Direct

Name: yvrG [H]

Synonym: BALH_1671

Alternate gene names: 118477353

Gene position: 1821837-1823273 (Clockwise)

Preceding gene: 118477352

Following gene: 118477354

Centisome position: 34.65

GC content: 40.64

Gene sequence:

>1437_bases
GTGGAAGGAATTACTCGTATATTACAGCGATTTGTCACCACGACCATCCTTATTTCAATATTTGTGCTTATTTTTAATTT
CGTGCTACTAGGTACCTTGGTATTCAATGAAACTAATCAACAAATCCCTCCGGAAGGTTTACTTAAAAAGATTTCTCAAA
ATCTAGACAAGCAGGATAACAACTATCATTTAGACGAGAACACCGCCAAGATTTTGCAGCACAATCAAGCGTGGGCTATG
CTGATTAGTGAAGACGGCCATGTGCAATGGGATTACCATTTACCTAATGATGTTCCGAGATTTTATAATTTAGTCGATGT
AGCTAAGTTATCGCGATATTATCTTTTGCAATATCCTGTTTATACTTGGGAACATGAAAATGACCTAATTGTGGTCGGAT
ATCCAAAGGGAAGTCACTGGAAGTATCAATTTACCTTTCTTTCTGATTGGTTAAGGGAGATACCCTTGCGGCTTGGTGTA
CTGTTGCTCTTTAATGTAGGGATAACTCTGTTGATTTCTGTTGTGATTGGTACACGTCTCATAAGAGGGATACGTCCTCT
TGTGTCAGGAGTCCACAATCTTGCTAGGGAGGAATTGGTTCAGTTGGATTCCAAGGGAATATTTGGTGACTTAGCTCAAA
GTATTAATTCTGCCTCCACTAAGCTCCAGAAAAAAACGGACGCGTTGAAGGCACGAGATGAAGCGCGTTCTAATTGGATT
GCCGGGATTTCTCACGATATCCGGACCCCACTTTCGATTATTCTTGGCTATGCAAGCGAAATGGAAGATAATTTTGACTT
GTCGGAGGACCAGAGGCGGCAGGCTGGTATCATTCGGCATCAGGGTGAGAAGCTCCGCTCACTTGTAAGTGATTTGAATC
TAGTCTCCATGCTTGAGTATGAAATGCAACCTTTGCATTTGAAGCAAATCCGTCTATCAGTTTTAGCGAGACAGGTGGCT
ACGGATTTTTTGAATAATGGGTTGGATGATCGTTATGAAATTGATTTGAAGCTGAATGTTGAAGCGGTTAAGGTTATTGG
AGACGAGAAATTGCTACTTCGTGCAATTAGTAATCTTGTCCAAAATAGTGTAAATCATAACACACAGGGATGTGTAATCA
CGTTGGAAACCTCTCTATCCAAGGATCGCTCCCAATATCGCTTTATTGTAAAGGATAATGGGCGGGGAATCCCAAAGGAG
AAATTGACGGAAATTACCGAGTTACCTTATTCGTCAAGAAGAAAGCGGACTGTCAAAGAAGGCCATGGCCTAGGAATTCC
GATGGTGGCAAGGATTGTGCAGGCTCATCACGGACGTCTATTTATTTCTAGTAATGGGGATCGAGGAGGTCTAACGACTG
TTATAGAATTACCTGCGCATCATGATGAAAAATTAGAAAAAAGTAAAAAAGATGAAAAATCAGAAAAAATAAAGTAA

Upstream 100 bases:

>100_bases
GCGGATACGTGAAAAGATTGAGCTGGATCCTTCCAAACCAATCTATCTTCTCACCTTCAGGGGATTGGGATATAAATTGC
TAGTAAAGGAGACGTATTGA

Downstream 100 bases:

>100_bases
ATATGAACTAATTATTACTTAATTATACATCTAGTGGACAAGCTGCTTATTTTAATAATTTTGTTATGTAACTTTTTATA
ACGTTGTACATAGAAATGTC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MEGITRILQRFVTTTILISIFVLIFNFVLLGTLVFNETNQQIPPEGLLKKISQNLDKQDNNYHLDENTAKILQHNQAWAM
LISEDGHVQWDYHLPNDVPRFYNLVDVAKLSRYYLLQYPVYTWEHENDLIVVGYPKGSHWKYQFTFLSDWLREIPLRLGV
LLLFNVGITLLISVVIGTRLIRGIRPLVSGVHNLAREELVQLDSKGIFGDLAQSINSASTKLQKKTDALKARDEARSNWI
AGISHDIRTPLSIILGYASEMEDNFDLSEDQRRQAGIIRHQGEKLRSLVSDLNLVSMLEYEMQPLHLKQIRLSVLARQVA
TDFLNNGLDDRYEIDLKLNVEAVKVIGDEKLLLRAISNLVQNSVNHNTQGCVITLETSLSKDRSQYRFIVKDNGRGIPKE
KLTEITELPYSSRRKRTVKEGHGLGIPMVARIVQAHHGRLFISSNGDRGGLTTVIELPAHHDEKLEKSKKDEKSEKIK

Sequences:

>Translated_478_residues
MEGITRILQRFVTTTILISIFVLIFNFVLLGTLVFNETNQQIPPEGLLKKISQNLDKQDNNYHLDENTAKILQHNQAWAM
LISEDGHVQWDYHLPNDVPRFYNLVDVAKLSRYYLLQYPVYTWEHENDLIVVGYPKGSHWKYQFTFLSDWLREIPLRLGV
LLLFNVGITLLISVVIGTRLIRGIRPLVSGVHNLAREELVQLDSKGIFGDLAQSINSASTKLQKKTDALKARDEARSNWI
AGISHDIRTPLSIILGYASEMEDNFDLSEDQRRQAGIIRHQGEKLRSLVSDLNLVSMLEYEMQPLHLKQIRLSVLARQVA
TDFLNNGLDDRYEIDLKLNVEAVKVIGDEKLLLRAISNLVQNSVNHNTQGCVITLETSLSKDRSQYRFIVKDNGRGIPKE
KLTEITELPYSSRRKRTVKEGHGLGIPMVARIVQAHHGRLFISSNGDRGGLTTVIELPAHHDEKLEKSKKDEKSEKIK
>Mature_478_residues
MEGITRILQRFVTTTILISIFVLIFNFVLLGTLVFNETNQQIPPEGLLKKISQNLDKQDNNYHLDENTAKILQHNQAWAM
LISEDGHVQWDYHLPNDVPRFYNLVDVAKLSRYYLLQYPVYTWEHENDLIVVGYPKGSHWKYQFTFLSDWLREIPLRLGV
LLLFNVGITLLISVVIGTRLIRGIRPLVSGVHNLAREELVQLDSKGIFGDLAQSINSASTKLQKKTDALKARDEARSNWI
AGISHDIRTPLSIILGYASEMEDNFDLSEDQRRQAGIIRHQGEKLRSLVSDLNLVSMLEYEMQPLHLKQIRLSVLARQVA
TDFLNNGLDDRYEIDLKLNVEAVKVIGDEKLLLRAISNLVQNSVNHNTQGCVITLETSLSKDRSQYRFIVKDNGRGIPKE
KLTEITELPYSSRRKRTVKEGHGLGIPMVARIVQAHHGRLFISSNGDRGGLTTVIELPAHHDEKLEKSKKDEKSEKIK

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon. Probably activates yv

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=296, Percent_Identity=26.6891891891892, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=31.6742081447964, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786783, Length=325, Percent_Identity=25.8461538461538, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=260, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789149, Length=335, Percent_Identity=25.0746268656716, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786912, Length=258, Percent_Identity=26.3565891472868, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789403, Length=324, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=241, Percent_Identity=25.7261410788382, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI145693157, Length=279, Percent_Identity=24.0143369175627, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790861, Length=305, Percent_Identity=25.9016393442623, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54581; Mature: 54581

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGITRILQRFVTTTILISIFVLIFNFVLLGTLVFNETNQQIPPEGLLKKISQNLDKQDN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCC
NYHLDENTAKILQHNQAWAMLISEDGHVQWDYHLPNDVPRFYNLVDVAKLSRYYLLQYPV
CEECCCHHHHHHHCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHEECCE
YTWEHENDLIVVGYPKGSHWKYQFTFLSDWLREIPLRLGVLLLFNVGITLLISVVIGTRL
EEEECCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRGIRPLVSGVHNLAREELVQLDSKGIFGDLAQSINSASTKLQKKTDALKARDEARSNWI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGISHDIRTPLSIILGYASEMEDNFDLSEDQRRQAGIIRHQGEKLRSLVSDLNLVSMLEY
HCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EMQPLHLKQIRLSVLARQVATDFLNNGLDDRYEIDLKLNVEAVKVIGDEKLLLRAISNLV
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCHHHHHHHHHHHH
QNSVNHNTQGCVITLETSLSKDRSQYRFIVKDNGRGIPKEKLTEITELPYSSRRKRTVKE
HHHCCCCCCCEEEEEECCCCCCCHHEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHH
GHGLGIPMVARIVQAHHGRLFISSNGDRGGLTTVIELPAHHDEKLEKSKKDEKSEKIK
CCCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEGITRILQRFVTTTILISIFVLIFNFVLLGTLVFNETNQQIPPEGLLKKISQNLDKQDN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCC
NYHLDENTAKILQHNQAWAMLISEDGHVQWDYHLPNDVPRFYNLVDVAKLSRYYLLQYPV
CEECCCHHHHHHHCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHEECCE
YTWEHENDLIVVGYPKGSHWKYQFTFLSDWLREIPLRLGVLLLFNVGITLLISVVIGTRL
EEEECCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRGIRPLVSGVHNLAREELVQLDSKGIFGDLAQSINSASTKLQKKTDALKARDEARSNWI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGISHDIRTPLSIILGYASEMEDNFDLSEDQRRQAGIIRHQGEKLRSLVSDLNLVSMLEY
HCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EMQPLHLKQIRLSVLARQVATDFLNNGLDDRYEIDLKLNVEAVKVIGDEKLLLRAISNLV
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCHHHHHHHHHHHH
QNSVNHNTQGCVITLETSLSKDRSQYRFIVKDNGRGIPKEKLTEITELPYSSRRKRTVKE
HHHCCCCCCCEEEEEECCCCCCCHHEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHH
GHGLGIPMVARIVQAHHGRLFISSNGDRGGLTTVIELPAHHDEKLEKSKKDEKSEKIK
CCCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]