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The map label for this gene is pbpE [H]

Identifier: 118477321

GI number: 118477321

Start: 1784542

End: 1785522

Strand: Reverse

Name: pbpE [H]

Synonym: BALH_1638

Alternate gene names: 118477321

Gene position: 1785522-1784542 (Counterclockwise)

Preceding gene: 118477329

Following gene: 118477318

Centisome position: 33.96

GC content: 30.78

Gene sequence:

>981_bases
TTGTTAAACTCGTATATTAATTCATTTTTATATAAAAATGATGAAAAATTTAACGGAACAATTTTAATAGCCCATAAAGA
AGAGACTCTTTATAAGCAGTCATTTGGAAAAGCTAATTATAATTGGGACATACCTAATACATCTACAACGAAGTTTCGTA
TCGGATCAATAACTAAAATCTTCACAGCAGTTTCAATTTTAATGCTTGTGGAAGAGGAAAAATTACAGCTACATGATACT
TTAGATCAATTCATTCCCGATTTCCCAAAAGGAAATCAGATTATGATCAAGCATTTACTAAATCATACTGCTGGTGTTGG
TAACATTACTGCTCAACATGACTTTTTATTACAATCTTTACAGCCTCGAACACCAGATGAATTAATACAATGGATTATTG
CATGCCCCTTTGAATCTAACCCTGGCGAAAAATTCAATTATTCAAATTCGGGGTATATTATATTAGGAAAAATTATTGAA
GTTATAAGTGGAATGTCTTATGAGGAATTTCTTAAAAATAAAATTTTCTATCCAATCTCTATAATGAACACAAGTATTGA
TTTGAATCACACTATTCAAAAACATAAAGCAACTGGCTATGAGTTACATCCAAATCAAGGCCTACAGAACGCATCATTTA
TTCATATGTCTAATTCATATTCAGCCGGTGGATTAGTTTCTACAGCCATAGATTTATATAGATTTGATAAGGCGCTAAAA
GAAAATCGTTTCTTATCAAGTAGGATGACGTCTCGTATGCTTACTGCAGAATCTTACGGATATGGTTACGGTTGGAATAT
TGCTATAACTGAAAAAAATAATAAACTTATATTTCATCACGGAGGAATTAACGGCTTTACGTCCTCCTATTTACGATTAA
TTGACAAAGAGGCTACAATCATCATTTTAAGCAATGTATCAACACTATTAACATCAACTCTTGCTAATGAAATCGCTTCT
TATATAGAAAATAATTTTTAA

Upstream 100 bases:

>100_bases
AAAAGTAATATAAAAACATTTCATTTAGGGGGAATTGCCTATGCCGTTGGATTCCATTTCAGGTAACGAATATTCCAAAA
TTTAAAGGAGTGCCTGAAAT

Downstream 100 bases:

>100_bases
ATCTATTATGATTTGAAAAACCGTTCAGCGTTTTGAACGGTTTTTCAAACAATTTAGTTCACCTTAGCTCCATAGCATCT
AGCTACCGCAACTGCCTGTG

Product: beta-lactamase

Products: NA

Alternate protein names: PBP 4*; PBP 4A; Penicillin-binding protein E [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLNSYINSFLYKNDEKFNGTILIAHKEETLYKQSFGKANYNWDIPNTSTTKFRIGSITKIFTAVSILMLVEEEKLQLHDT
LDQFIPDFPKGNQIMIKHLLNHTAGVGNITAQHDFLLQSLQPRTPDELIQWIIACPFESNPGEKFNYSNSGYIILGKIIE
VISGMSYEEFLKNKIFYPISIMNTSIDLNHTIQKHKATGYELHPNQGLQNASFIHMSNSYSAGGLVSTAIDLYRFDKALK
ENRFLSSRMTSRMLTAESYGYGYGWNIAITEKNNKLIFHHGGINGFTSSYLRLIDKEATIIILSNVSTLLTSTLANEIAS
YIENNF

Sequences:

>Translated_326_residues
MLNSYINSFLYKNDEKFNGTILIAHKEETLYKQSFGKANYNWDIPNTSTTKFRIGSITKIFTAVSILMLVEEEKLQLHDT
LDQFIPDFPKGNQIMIKHLLNHTAGVGNITAQHDFLLQSLQPRTPDELIQWIIACPFESNPGEKFNYSNSGYIILGKIIE
VISGMSYEEFLKNKIFYPISIMNTSIDLNHTIQKHKATGYELHPNQGLQNASFIHMSNSYSAGGLVSTAIDLYRFDKALK
ENRFLSSRMTSRMLTAESYGYGYGWNIAITEKNNKLIFHHGGINGFTSSYLRLIDKEATIIILSNVSTLLTSTLANEIAS
YIENNF
>Mature_326_residues
MLNSYINSFLYKNDEKFNGTILIAHKEETLYKQSFGKANYNWDIPNTSTTKFRIGSITKIFTAVSILMLVEEEKLQLHDT
LDQFIPDFPKGNQIMIKHLLNHTAGVGNITAQHDFLLQSLQPRTPDELIQWIIACPFESNPGEKFNYSNSGYIILGKIIE
VISGMSYEEFLKNKIFYPISIMNTSIDLNHTIQKHKATGYELHPNQGLQNASFIHMSNSYSAGGLVSTAIDLYRFDKALK
ENRFLSSRMTSRMLTAESYGYGYGWNIAITEKNNKLIFHHGGINGFTSSYLRLIDKEATIIILSNVSTLLTSTLANEIAS
YIENNF

Specific function: Probably involved in peptidoglycan modification during cortex synthesis [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI87082101, Length=181, Percent_Identity=24.8618784530387, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790593, Length=345, Percent_Identity=23.1884057971014, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17550934, Length=296, Percent_Identity=29.7297297297297, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115533026, Length=352, Percent_Identity=23.5795454545455, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17565630, Length=280, Percent_Identity=27.8571428571429, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR021860 [H]

Pfam domain/function: PF00144 Beta-lactamase; PF11954 DUF3471 [H]

EC number: NA

Molecular weight: Translated: 37013; Mature: 37013

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSYINSFLYKNDEKFNGTILIAHKEETLYKQSFGKANYNWDIPNTSTTKFRIGSITKI
CCHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHCCCCCCEECCCCCCCCEEECCHHHHH
FTAVSILMLVEEEKLQLHDTLDQFIPDFPKGNQIMIKHLLNHTAGVGNITAQHDFLLQSL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHC
QPRTPDELIQWIIACPFESNPGEKFNYSNSGYIILGKIIEVISGMSYEEFLKNKIFYPIS
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCHHHHHHCCCEEEEE
IMNTSIDLNHTIQKHKATGYELHPNQGLQNASFIHMSNSYSAGGLVSTAIDLYRFDKALK
EEECCCCHHHHHHHHCCCCEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
ENRFLSSRMTSRMLTAESYGYGYGWNIAITEKNNKLIFHHGGINGFTSSYLRLIDKEATI
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHCCCCEE
IILSNVSTLLTSTLANEIASYIENNF
EEECCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLNSYINSFLYKNDEKFNGTILIAHKEETLYKQSFGKANYNWDIPNTSTTKFRIGSITKI
CCHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHCCCCCCEECCCCCCCCEEECCHHHHH
FTAVSILMLVEEEKLQLHDTLDQFIPDFPKGNQIMIKHLLNHTAGVGNITAQHDFLLQSL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHC
QPRTPDELIQWIIACPFESNPGEKFNYSNSGYIILGKIIEVISGMSYEEFLKNKIFYPIS
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCHHHHHHCCCEEEEE
IMNTSIDLNHTIQKHKATGYELHPNQGLQNASFIHMSNSYSAGGLVSTAIDLYRFDKALK
EEECCCCHHHHHHHHCCCCEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
ENRFLSSRMTSRMLTAESYGYGYGWNIAITEKNNKLIFHHGGINGFTSSYLRLIDKEATI
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHCCCCEE
IILSNVSTLLTSTLANEIASYIENNF
EEECCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8491712; 9384377 [H]