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The map label for this gene is yhcY [H]

Identifier: 118476318

GI number: 118476318

Start: 666351

End: 668183

Strand: Direct

Name: yhcY [H]

Synonym: BALH_0573

Alternate gene names: 118476318

Gene position: 666351-668183 (Clockwise)

Preceding gene: 118476314

Following gene: 118476319

Centisome position: 12.68

GC content: 33.06

Gene sequence:

>1833_bases
TTGAAGGATGTAAATTCTATCTTTATGAGAGAAAAGATTGCTAGTTCTTATCTTTATTTTATTTCTTTTCTTGGTTTCAT
TACTATAACTATATCTTTACTTGAAATTAAAATCCCTTCTCATTCAACAATACTAATATTGTTATTAATATTTATGGGGA
TTACAGAGTATTTTCCTGTACGATTTTGGAGAGGAACGAGCTCGCTTACCTTTCCTATAATTTACGCTATGAGTTGGCAG
TTTGGAATCCATATAACTATTATTGCTATTGTACTCGTAACGTTAATTATTCACCTGCATCGTCGTTCACCAATACAAAG
AATGTTATTTAATAGTACTCAGCATGCGCTTAGTTTGATCTTGGCCGAATGGTTTTCAAATAAATGTATGCTCTTATTAA
TTAACAAGATAGATATGTCAGTTCTGTATGAAAATTTAATATCTTTATTATTATTTTGCGTGTTTTTTTGTTTTTTTAAC
AACCGCTTTTACGATTTGTTAATGATACTCCTTCCACAGCCATATTCAATCTATCAGTGGTATAAAAAAACTGTAACGGT
ATTTCTTTGCGAAACTTTTGGTTTCTCTTATACGGCCTTGATGCATGTATTAATTAGTACATATAGTGTGGAAGTAAACG
AGATTACAGTACTGTTTTTCTTTTTTCCACTTGTAGCAACTTCAGTTATTAGTTCTTTTTCTGTAAGGATAAGGATGGAG
AAGGAGCGGTTATATGAGCTATTTCTTATTACGACCGAAATTAGTCGAGGACTAACAGGAGGAAACTTGAAGCATATTAA
ACAAGCACTTAAAGGTTTTTTCGGCATACAAGCATATGTAATATGGACAAAAGATGATGAGAACTGGAATATTCTATTAA
AAGATGGGAAAGTCCGCTCTCATATTTCTGATCATTCAGAAAAAAACAAGGCGTTTGAGGAACTCTCTAAAAATCTAGTA
TTTAATAATTGGAAAATTGGTACGGCTCCTGAAGATGAAATATTTGATAGTGTCATACGCTCACTTGTGTATTTTCCTCT
TATTGTAAATGGTGAACTAGTTGGGATGTTTGTTGCAGTGAAAAGTAGAACTGCAGGTTTTTTTCCGGAAGATGTACAGT
CGTTAGCTACATTTTCTAACCAATTAGCTAACGTAGTTAAAACAAGGATACTGATTTCTGAACAAGAAAAAAGAATGATT
TTAGAAGAAAGAAATAGAATAGCACGCGAAATTCATGATGGTATTGCGCAAACATTGGCCGGGGTGATATATCAATTAGA
ATCCGCACAAAAAAAATATCGCGATAAACCAATAGATATGCAGCAAATAGTAGAGAAAAGCATAAAAGATTTAAGGGGAA
GCTTAGGGGAAGTTCGCTATTCTATTTATGCTTTAAAACCATATCCGACACAACAATTAGGGCTAAAACAGGCGATAGCA
AGTAAAATAAAATCTTTAAAACAAGAATATGAACTAGATATTACATATCATGAAAGAGGTCATGCACGTGCGCTTAGCTT
TTCAAAAGAAAGAGTTATTTTTGATACATTACAAGAGAGTTTGCAAAACATTGTAAAACATGCACAAGCAGACAAGACTG
ATGTTTTACTTAGCTATCAAAGTGAGCACGTGCTTTTAAGGGTTAAGGATAATGGGGTTGGTTTTTCGCTATTTGAGTCT
ATGGTTAAAACGAAGAATGAGCCACATTATGGTATATTACATATGAATGAACAAGCTGAACAATTAGGGGCTACTTTACA
GATTGATAGTTCTGTAGGGAAAGGGACAGAAATTACACTATTAATTCCAGATTTACAAACAAGGGGTGCGTAA

Upstream 100 bases:

>100_bases
AGCCGGTGATTGGCTAGTGGAGGTTCTTCCATTTTGCCAGTGCCGGTTTTTTATTGGATAATAGAGAAAATGAAGTTTTA
TAAAGAAAGAAGGGGTTGTT

Downstream 100 bases:

>100_bases
AATGATTAAAATATTAGTAGTGGATGATCATGCTTTTTTACGAGACGCAATTCGGAGCATACTAGAGGATGAATCTGATA
TGAACGTGGTTGGAGAAGCT

Product: sensor histidine kinase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MKDVNSIFMREKIASSYLYFISFLGFITITISLLEIKIPSHSTILILLLIFMGITEYFPVRFWRGTSSLTFPIIYAMSWQ
FGIHITIIAIVLVTLIIHLHRRSPIQRMLFNSTQHALSLILAEWFSNKCMLLLINKIDMSVLYENLISLLLFCVFFCFFN
NRFYDLLMILLPQPYSIYQWYKKTVTVFLCETFGFSYTALMHVLISTYSVEVNEITVLFFFFPLVATSVISSFSVRIRME
KERLYELFLITTEISRGLTGGNLKHIKQALKGFFGIQAYVIWTKDDENWNILLKDGKVRSHISDHSEKNKAFEELSKNLV
FNNWKIGTAPEDEIFDSVIRSLVYFPLIVNGELVGMFVAVKSRTAGFFPEDVQSLATFSNQLANVVKTRILISEQEKRMI
LEERNRIAREIHDGIAQTLAGVIYQLESAQKKYRDKPIDMQQIVEKSIKDLRGSLGEVRYSIYALKPYPTQQLGLKQAIA
SKIKSLKQEYELDITYHERGHARALSFSKERVIFDTLQESLQNIVKHAQADKTDVLLSYQSEHVLLRVKDNGVGFSLFES
MVKTKNEPHYGILHMNEQAEQLGATLQIDSSVGKGTEITLLIPDLQTRGA

Sequences:

>Translated_610_residues
MKDVNSIFMREKIASSYLYFISFLGFITITISLLEIKIPSHSTILILLLIFMGITEYFPVRFWRGTSSLTFPIIYAMSWQ
FGIHITIIAIVLVTLIIHLHRRSPIQRMLFNSTQHALSLILAEWFSNKCMLLLINKIDMSVLYENLISLLLFCVFFCFFN
NRFYDLLMILLPQPYSIYQWYKKTVTVFLCETFGFSYTALMHVLISTYSVEVNEITVLFFFFPLVATSVISSFSVRIRME
KERLYELFLITTEISRGLTGGNLKHIKQALKGFFGIQAYVIWTKDDENWNILLKDGKVRSHISDHSEKNKAFEELSKNLV
FNNWKIGTAPEDEIFDSVIRSLVYFPLIVNGELVGMFVAVKSRTAGFFPEDVQSLATFSNQLANVVKTRILISEQEKRMI
LEERNRIAREIHDGIAQTLAGVIYQLESAQKKYRDKPIDMQQIVEKSIKDLRGSLGEVRYSIYALKPYPTQQLGLKQAIA
SKIKSLKQEYELDITYHERGHARALSFSKERVIFDTLQESLQNIVKHAQADKTDVLLSYQSEHVLLRVKDNGVGFSLFES
MVKTKNEPHYGILHMNEQAEQLGATLQIDSSVGKGTEITLLIPDLQTRGA
>Mature_610_residues
MKDVNSIFMREKIASSYLYFISFLGFITITISLLEIKIPSHSTILILLLIFMGITEYFPVRFWRGTSSLTFPIIYAMSWQ
FGIHITIIAIVLVTLIIHLHRRSPIQRMLFNSTQHALSLILAEWFSNKCMLLLINKIDMSVLYENLISLLLFCVFFCFFN
NRFYDLLMILLPQPYSIYQWYKKTVTVFLCETFGFSYTALMHVLISTYSVEVNEITVLFFFFPLVATSVISSFSVRIRME
KERLYELFLITTEISRGLTGGNLKHIKQALKGFFGIQAYVIWTKDDENWNILLKDGKVRSHISDHSEKNKAFEELSKNLV
FNNWKIGTAPEDEIFDSVIRSLVYFPLIVNGELVGMFVAVKSRTAGFFPEDVQSLATFSNQLANVVKTRILISEQEKRMI
LEERNRIAREIHDGIAQTLAGVIYQLESAQKKYRDKPIDMQQIVEKSIKDLRGSLGEVRYSIYALKPYPTQQLGLKQAIA
SKIKSLKQEYELDITYHERGHARALSFSKERVIFDTLQESLQNIVKHAQADKTDVLLSYQSEHVLLRVKDNGVGFSLFES
MVKTKNEPHYGILHMNEQAEQLGATLQIDSSVGKGTEITLLIPDLQTRGA

Specific function: Member of the two-component regulatory system yhcY/yhcZ. Probably activates yhcZ by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=314, Percent_Identity=21.3375796178344, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788812, Length=207, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87082311, Length=206, Percent_Identity=30.5825242718447, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70225; Mature: 70225

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDVNSIFMREKIASSYLYFISFLGFITITISLLEIKIPSHSTILILLLIFMGITEYFPV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHCCC
RFWRGTSSLTFPIIYAMSWQFGIHITIIAIVLVTLIIHLHRRSPIQRMLFNSTQHALSLI
EEECCCCCCHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHH
LAEWFSNKCMLLLINKIDMSVLYENLISLLLFCVFFCFFNNRFYDLLMILLPQPYSIYQW
HHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHH
YKKTVTVFLCETFGFSYTALMHVLISTYSVEVNEITVLFFFFPLVATSVISSFSVRIRME
HHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
KERLYELFLITTEISRGLTGGNLKHIKQALKGFFGIQAYVIWTKDDENWNILLKDGKVRS
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCHHH
HISDHSEKNKAFEELSKNLVFNNWKIGTAPEDEIFDSVIRSLVYFPLIVNGELVGMFVAV
HHHCCHHHHHHHHHHHHHHEECCEECCCCCHHHHHHHHHHHHHHHHHEECCCEEEEEEEE
KSRTAGFFPEDVQSLATFSNQLANVVKTRILISEQEKRMILEERNRIAREIHDGIAQTLA
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVIYQLESAQKKYRDKPIDMQQIVEKSIKDLRGSLGEVRYSIYALKPYPTQQLGLKQAIA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHEEEEEEEECCCCCHHHHHHHHHH
SKIKSLKQEYELDITYHERGHARALSFSKERVIFDTLQESLQNIVKHAQADKTDVLLSYQ
HHHHHHHHHHCEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
SEHVLLRVKDNGVGFSLFESMVKTKNEPHYGILHMNEQAEQLGATLQIDSSVGKGTEITL
CCEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHCCCEEEEECCCCCCCEEEE
LIPDLQTRGA
EECCHHCCCC
>Mature Secondary Structure
MKDVNSIFMREKIASSYLYFISFLGFITITISLLEIKIPSHSTILILLLIFMGITEYFPV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHCCC
RFWRGTSSLTFPIIYAMSWQFGIHITIIAIVLVTLIIHLHRRSPIQRMLFNSTQHALSLI
EEECCCCCCHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHH
LAEWFSNKCMLLLINKIDMSVLYENLISLLLFCVFFCFFNNRFYDLLMILLPQPYSIYQW
HHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHH
YKKTVTVFLCETFGFSYTALMHVLISTYSVEVNEITVLFFFFPLVATSVISSFSVRIRME
HHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
KERLYELFLITTEISRGLTGGNLKHIKQALKGFFGIQAYVIWTKDDENWNILLKDGKVRS
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCHHH
HISDHSEKNKAFEELSKNLVFNNWKIGTAPEDEIFDSVIRSLVYFPLIVNGELVGMFVAV
HHHCCHHHHHHHHHHHHHHEECCEECCCCCHHHHHHHHHHHHHHHHHEECCCEEEEEEEE
KSRTAGFFPEDVQSLATFSNQLANVVKTRILISEQEKRMILEERNRIAREIHDGIAQTLA
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVIYQLESAQKKYRDKPIDMQQIVEKSIKDLRGSLGEVRYSIYALKPYPTQQLGLKQAIA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHEEEEEEEECCCCCHHHHHHHHHH
SKIKSLKQEYELDITYHERGHARALSFSKERVIFDTLQESLQNIVKHAQADKTDVLLSYQ
HHHHHHHHHHCEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
SEHVLLRVKDNGVGFSLFESMVKTKNEPHYGILHMNEQAEQLGATLQIDSSVGKGTEITL
CCEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHCCCEEEEECCCCCCCEEEE
LIPDLQTRGA
EECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]