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The map label for this gene is vraR [H]

Identifier: 118476319

GI number: 118476319

Start: 668176

End: 668826

Strand: Direct

Name: vraR [H]

Synonym: BALH_0574

Alternate gene names: 118476319

Gene position: 668176-668826 (Clockwise)

Preceding gene: 118476318

Following gene: 118476320

Centisome position: 12.71

GC content: 35.33

Gene sequence:

>651_bases
GTGCGTAAAATGATTAAAATATTAGTAGTGGATGATCATGCTTTTTTACGAGACGCAATTCGGAGCATACTAGAGGATGA
ATCTGATATGAACGTGGTTGGAGAAGCTAGCTCTGGGGACGGAGTATTGGAAAAAGTAGAAGCATGCAGACCAGATTGTA
TTTTGATGGATATTAATCTTCCGGGGAAAAATGGTATTGAAGCTACAGAGTTGGTGAAAAAAAACTATCCGAATTGCCGA
GTACTTGTGTTTACAATGTATGAGCATGATGAGTATTTAATGGATGCACTTCAGGCTGGTGCTGATGGGTATTTATTGAA
AGATTCATCATCGGAGCAGGTAGTAGCAGCAATTCGGATGTTATATCGAGGCGATTCCGTTATTCATCCGCGTATGACTA
AAAAATTAATTACATATCATCAGCAAAAAATGAAAGTAGAATCAAATGAAAATGAACTGACGGAACGTGAAAAGGAAATT
CTCTTTGAATTAGTAAAAGGACTTAGTAATAAAGAAATTGCTGAAGCTCTGTATATTAGTGATAAAACAGTTAAAATTCA
CATCAATAAAATTTTTAAAAAACTAAATGTGAAAAGTCGATCGCAAGCAGTGATTTATGCTGTTCGAAATCAATTGGTTC
CGTTGGATTAA

Upstream 100 bases:

>100_bases
AATGAACAAGCTGAACAATTAGGGGCTACTTTACAGATTGATAGTTCTGTAGGGAAAGGGACAGAAATTACACTATTAAT
TCCAGATTTACAAACAAGGG

Downstream 100 bases:

>100_bases
ATAAGAGATCTTTAAAAGAACTATCGTGTTTCTTTATTCTATATTACAAAGAATAAAGAGCAAGGTAGTTCTTTTGTACT
ATGCAGACATAGAATCATTA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MRKMIKILVVDDHAFLRDAIRSILEDESDMNVVGEASSGDGVLEKVEACRPDCILMDINLPGKNGIEATELVKKNYPNCR
VLVFTMYEHDEYLMDALQAGADGYLLKDSSSEQVVAAIRMLYRGDSVIHPRMTKKLITYHQQKMKVESNENELTEREKEI
LFELVKGLSNKEIAEALYISDKTVKIHINKIFKKLNVKSRSQAVIYAVRNQLVPLD

Sequences:

>Translated_216_residues
MRKMIKILVVDDHAFLRDAIRSILEDESDMNVVGEASSGDGVLEKVEACRPDCILMDINLPGKNGIEATELVKKNYPNCR
VLVFTMYEHDEYLMDALQAGADGYLLKDSSSEQVVAAIRMLYRGDSVIHPRMTKKLITYHQQKMKVESNENELTEREKEI
LFELVKGLSNKEIAEALYISDKTVKIHINKIFKKLNVKSRSQAVIYAVRNQLVPLD
>Mature_216_residues
MRKMIKILVVDDHAFLRDAIRSILEDESDMNVVGEASSGDGVLEKVEACRPDCILMDINLPGKNGIEATELVKKNYPNCR
VLVFTMYEHDEYLMDALQAGADGYLLKDSSSEQVVAAIRMLYRGDSVIHPRMTKKLITYHQQKMKVESNENELTEREKEI
LFELVKGLSNKEIAEALYISDKTVKIHINKIFKKLNVKSRSQAVIYAVRNQLVPLD

Specific function: Member of the two-component regulatory system yfiJ/yfiK [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=212, Percent_Identity=35.8490566037736, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788521, Length=204, Percent_Identity=35.2941176470588, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1787473, Length=201, Percent_Identity=37.8109452736318, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=26.5700483091787, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786747, Length=211, Percent_Identity=29.8578199052133, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1790102, Length=196, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1787277, Length=100, Percent_Identity=44, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI87082052, Length=119, Percent_Identity=32.7731092436975, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788546, Length=216, Percent_Identity=23.6111111111111, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786599, Length=217, Percent_Identity=28.110599078341, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24603; Mature: 24603

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKMIKILVVDDHAFLRDAIRSILEDESDMNVVGEASSGDGVLEKVEACRPDCILMDINL
CCCEEEEEEECCHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHCCCCEEEEEEEC
PGKNGIEATELVKKNYPNCRVLVFTMYEHDEYLMDALQAGADGYLLKDSSSEQVVAAIRM
CCCCCCHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
LYRGDSVIHPRMTKKLITYHQQKMKVESNENELTEREKEILFELVKGLSNKEIAEALYIS
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHEEC
DKTVKIHINKIFKKLNVKSRSQAVIYAVRNQLVPLD
CCEEEEEHHHHHHHHCCCCCCHHHHEEECCCCCCCC
>Mature Secondary Structure
MRKMIKILVVDDHAFLRDAIRSILEDESDMNVVGEASSGDGVLEKVEACRPDCILMDINL
CCCEEEEEEECCHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHCCCCEEEEEEEC
PGKNGIEATELVKKNYPNCRVLVFTMYEHDEYLMDALQAGADGYLLKDSSSEQVVAAIRM
CCCCCCHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
LYRGDSVIHPRMTKKLITYHQQKMKVESNENELTEREKEILFELVKGLSNKEIAEALYIS
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHEEC
DKTVKIHINKIFKKLNVKSRSQAVIYAVRNQLVPLD
CCEEEEEHHHHHHHHCCCCCCHHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8973323; 9384377 [H]