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The map label for this gene is arcB [H]

Identifier: 118476119

GI number: 118476119

Start: 416265

End: 417263

Strand: Direct

Name: arcB [H]

Synonym: BALH_0363

Alternate gene names: 118476119

Gene position: 416265-417263 (Clockwise)

Preceding gene: 118476118

Following gene: 118476120

Centisome position: 7.92

GC content: 35.14

Gene sequence:

>999_bases
ATGTTAATGACTAGACCAAATCTAAAAGGAAGAAGCTTTCTAGCAGAAAAAGATTTTACACAAGAAGAATTGTTATATTT
TCTAGATTTAGCAGCAGAATTAAAAGAGAAAAAGAAAAATGGTATCCCGCATCATTATTTAGAAGGTAAAAATGTAGCGC
TCTTATTTGAAAAAACTTCTACTCGTACGCGTTGTGCATTTACAGTAGCATGTACAGATTTAGGTGCGAACCCTGAATAT
TTAGGGAAAGGTGATATTCAGCTTGGGAAAAAAGAATCCGTAGAGGATACAGCAAAAGTGTTAGGGCGTATGTTTGACGG
AATTGAGTTTCGTGGATTTAATCATGAAACTGTAGAATCTTTAGCACAAAATTCTGGTGTGCCGGTTTGGAATGGATTAA
CAGACATGTGGCATCCAACACAAACACTAGCAGATTTATTAACAATTAGAGAACATGTAGGGAAATTAAAAAATGTGAAG
CTTGTCTATGTTGGAGATGGACGAAATAATGTTGCTAATAGTTTACTAGTGGGTGGAGCAATCGTTGGAATGGATGTACG
TATTTGTACACCGGAATCATTATGGCCTGCACAAGAGGTAATTGATTTAGCAAAAAAATATAATGAACAGGTAATGATAA
CAAGTGATGTGGAAGAAGCTGTTGCGAATGCAGATGTAATTTATACAGATGTATGGGTGTCTATGGGGGAAGAAGAAAAA
TTTGCTGAGCGTGTTGAGTTATTGAAACCTTATCAAGTAAATATGAAAATGATTAAAAAAACAGGGAATGAAAACGTGAT
TTTCTTACATTGTTTACCTGCATTTCATGATGTCGAAACGATGTATGGCGAAGAAGTTTATGAGAAATATGGGTTGAAAG
AAATGGAGGTAACTGACGAAGTATTCCGCAGTAAACATTCAAAAGTATTTGATCAAGCTGAAAATAGAATGCATACAATT
AAAGCGGTTATGGCAGCTACTTTAGGAAACATGGAGTAA

Upstream 100 bases:

>100_bases
TTCGGAATTATCTCGTGGTCGTGGGGGTCCACGTTGCATGAGTATGCCAATTGTTCGTAAAGATATTTAGTATAAATAAC
GGAGAAAGTAGGGATGAAGT

Downstream 100 bases:

>100_bases
AGAAGAAAGGGAGTCTTCCTTTCTTCTTTCTCCTCCTTTAGACACTATCATTCACTATTGCTTTTGTATTGTTATTGCAA
TTAAAGAGAGGTGAGTGGAA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEY
LGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVK
LVYVGDGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSDVEEAVANADVIYTDVWVSMGEEEK
FAERVELLKPYQVNMKMIKKTGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTI
KAVMAATLGNME

Sequences:

>Translated_332_residues
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEY
LGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVK
LVYVGDGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSDVEEAVANADVIYTDVWVSMGEEEK
FAERVELLKPYQVNMKMIKKTGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTI
KAVMAATLGNME
>Mature_332_residues
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEY
LGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVK
LVYVGDGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSDVEEAVANADVIYTDVWVSMGEEEK
FAERVELLKPYQVNMKMIKKTGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTI
KAVMAATLGNME

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=332, Percent_Identity=39.4578313253012, Blast_Score=228, Evalue=4e-60,
Organism=Homo sapiens, GI18105007, Length=336, Percent_Identity=24.702380952381, Blast_Score=85, Evalue=9e-17,
Organism=Escherichia coli, GI1786469, Length=331, Percent_Identity=55.5891238670695, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1790703, Length=326, Percent_Identity=56.441717791411, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI48994908, Length=371, Percent_Identity=27.2237196765499, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI2367364, Length=339, Percent_Identity=27.7286135693215, Blast_Score=84, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193204318, Length=266, Percent_Identity=27.4436090225564, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322373, Length=337, Percent_Identity=35.0148367952522, Blast_Score=179, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6322331, Length=281, Percent_Identity=24.5551601423488, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24642586, Length=335, Percent_Identity=26.2686567164179, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37506; Mature: 37506

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCC
TRTRCAFTVACTDLGANPEYLGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVES
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCHHHHHH
LAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGDGRNNVANSLLVGGA
HHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCHHHCEEEEEEECCCCHHHHHHHHCCE
IVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSDVEEAVANADVIYTDVWVSMGEEEK
EEECEEEEECCCCCCCHHHHHHHHHHCCCCEEEECCHHHHHCCCCEEEEEHHHHCCCHHH
FAERVELLKPYQVNMKMIKKTGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDE
HHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHH
VFRSKHSKVFDQAENRMHTIKAVMAATLGNME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCC
TRTRCAFTVACTDLGANPEYLGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVES
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCHHHHHH
LAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGDGRNNVANSLLVGGA
HHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCHHHCEEEEEEECCCCHHHHHHHHCCE
IVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSDVEEAVANADVIYTDVWVSMGEEEK
EEECEEEEECCCCCCCHHHHHHHHHHCCCCEEEECCHHHHHCCCCEEEEEHHHHCCCHHH
FAERVELLKPYQVNMKMIKKTGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDE
HHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHH
VFRSKHSKVFDQAENRMHTIKAVMAATLGNME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA