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The map label for this gene is rmlC [H]

Identifier: 117919830

GI number: 117919830

Start: 1597487

End: 1598038

Strand: Direct

Name: rmlC [H]

Synonym: Shewana3_1382

Alternate gene names: 117919830

Gene position: 1597487-1598038 (Clockwise)

Preceding gene: 117919829

Following gene: 117919831

Centisome position: 32.13

GC content: 33.88

Gene sequence:

>552_bases
ATGAAGATAATTAATACTAAAATTCCAGATGTAAAAGTAATTGAACCAAAAGTGTTTGGTGATGAACGTGGTTTTTTCAT
GGAGACTTGGAACCAGAAGCAATTTGAAAATTTAGTAACGGGTAAGTCTACTACTTTTGTACAGGATAATCACTCAAAAT
CTAAAAGGGGTATACTCCGAGGGTTGCATTATCAAACTAAAGATACTCAAGGTAAATTAGTTAGAGTGATTAGTGGTGAG
GTATTTGATGTAGCAGTTGACATCCGTAAGGACTCGCCCACATTCGGACAATGGGTTGGAGAGTATCTTTCTGCAGAAAA
TAAGCGCCAGTTATGGATACCAGAAGGTTTTGCTCATGGTTTCTATGTTATTTCTAATGAATGTGAATTTGTCTATAAAT
GCACGAAATACTATAATCCAAATTATGAAAAATGTTTAATATGGAATGATTCTAATCTTCAGATTGATTGGCCTATCCCC
GAAACTGAAAGAGTATTGCTTTCATCTAAAGACTCAAATGGAATACCATTTGATAAAATTCAGTATCTTTAA

Upstream 100 bases:

>100_bases
ACTTAATGGGTTATTTTTAAATCATATTAGTTGCTTATTTCACTTCTAACTCATCCCCGGTATTAACAATTAAATTAAAG
ATTAACTATACACTAATTAT

Downstream 100 bases:

>100_bases
TAATATAACTGATAAGATTAGTTGCAAATGCATCTATAAGGTTGGCTTATTGTTATGTTATTTAGTGTAGATGTTGCAGG
TTTATTTTAGCTTTATCTCA

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKIINTKIPDVKVIEPKVFGDERGFFMETWNQKQFENLVTGKSTTFVQDNHSKSKRGILRGLHYQTKDTQGKLVRVISGE
VFDVAVDIRKDSPTFGQWVGEYLSAENKRQLWIPEGFAHGFYVISNECEFVYKCTKYYNPNYEKCLIWNDSNLQIDWPIP
ETERVLLSSKDSNGIPFDKIQYL

Sequences:

>Translated_183_residues
MKIINTKIPDVKVIEPKVFGDERGFFMETWNQKQFENLVTGKSTTFVQDNHSKSKRGILRGLHYQTKDTQGKLVRVISGE
VFDVAVDIRKDSPTFGQWVGEYLSAENKRQLWIPEGFAHGFYVISNECEFVYKCTKYYNPNYEKCLIWNDSNLQIDWPIP
ETERVLLSSKDSNGIPFDKIQYL
>Mature_183_residues
MKIINTKIPDVKVIEPKVFGDERGFFMETWNQKQFENLVTGKSTTFVQDNHSKSKRGILRGLHYQTKDTQGKLVRVISGE
VFDVAVDIRKDSPTFGQWVGEYLSAENKRQLWIPEGFAHGFYVISNECEFVYKCTKYYNPNYEKCLIWNDSNLQIDWPIP
ETERVLLSSKDSNGIPFDKIQYL

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=181, Percent_Identity=53.0386740331492, Blast_Score=198, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17550412, Length=174, Percent_Identity=48.8505747126437, Blast_Score=166, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21342; Mature: 21342

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIINTKIPDVKVIEPKVFGDERGFFMETWNQKQFENLVTGKSTTFVQDNHSKSKRGILR
CCCCCCCCCCEEEECCEEECCCCCCEEECCCHHHHHHHHCCCCEEEEECCCCCHHHHHHH
GLHYQTKDTQGKLVRVISGEVFDVAVDIRKDSPTFGQWVGEYLSAENKRQLWIPEGFAHG
CCCCCCCCCCCEEEEEECCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCCC
FYVISNECEFVYKCTKYYNPNYEKCLIWNDSNLQIDWPIPETERVLLSSKDSNGIPFDKI
EEEEECCCEEEEEEEHHCCCCCCEEEEECCCCEEEECCCCCCCEEEEECCCCCCCCHHHE
QYL
ECC
>Mature Secondary Structure
MKIINTKIPDVKVIEPKVFGDERGFFMETWNQKQFENLVTGKSTTFVQDNHSKSKRGILR
CCCCCCCCCCEEEECCEEECCCCCCEEECCCHHHHHHHHCCCCEEEEECCCCCHHHHHHH
GLHYQTKDTQGKLVRVISGEVFDVAVDIRKDSPTFGQWVGEYLSAENKRQLWIPEGFAHG
CCCCCCCCCCCEEEEEECCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCCC
FYVISNECEFVYKCTKYYNPNYEKCLIWNDSNLQIDWPIPETERVLLSSKDSNGIPFDKI
EEEEECCCEEEEEEEHHCCCCCCEEEEECCCCEEEECCCCCCCEEEEECCCCCCCCHHHE
QYL
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]