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The map label for this gene is dinB

Identifier: 117919398

GI number: 117919398

Start: 1110035

End: 1111114

Strand: Direct

Name: dinB

Synonym: Shewana3_0949

Alternate gene names: 117919398

Gene position: 1110035-1111114 (Clockwise)

Preceding gene: 117919397

Following gene: 117919400

Centisome position: 22.32

GC content: 50.56

Gene sequence:

>1080_bases
GTGCGAAAAATCATTCATATCGATATGGATTGCTATTTTGCTGCGGTGGAAATGCGGGATTTTCCCGAATACCGCGGTAA
GCCTTTGGCCGTCGGCGGCAGTCGGGTGCAGCGTGGCGTCATCAGCACTTGTAATTATGAGGCGCGCAAATTTGGTGTGC
GTTCTGCCATGGCGACGGGCTACGCATTGAAATTGTGTCCCGATCTTATCCTCGTTCCCGGTCGTATGCAGGTTTACAAA
GAGGTCTCACAGCAAATTCGCGCCATTTTCTGCCGCTACACAGAGTTAATCGAACCGCTTTCCCTCGATGAAGCCTATTT
AGATGTCAGCGATTGTAAGCTGTTTAAGGGCTCTGCCACTTTAATCGCCGAGGCAATTCGCCGGGATATTTTGGCCGAAA
CTGGGCTGACGGCATCGGCTGGCGTGGCGCCGATTAAATTTCTCGCTAAGGTCGCCTCTGATTTAAATAAACCCAACGGG
CAATGTGTTATTCCACCCGATGAGGTTGCCGAGTTCGTTAAAAGCTTATCCCTGCGGAAAATTCCCGGAGTAGGTAAGGT
GACCGCTGAAAAACTGTCTTCACTAGGCTTAAATACCTGCGCCGATGTGCAGGCTTATCCTAAGCAAGAGTTGATTGCTC
GTTTTGGTAAGTTTGGCACAGTGTTAGTCGAGCGGGCCCATGGCATCGATGAACGTGGAATTTCGGTTAGCCGCGAGCGC
AAATCTGTGGGGGTTGAGACCACACTCGCTCAGGATATTTACACGCTTGAGCAGTGTCAGCAGGTGATGCCGGGATTAAT
TCAAGAGCTGTCCAGCCGTTTAGGGCGAAGCGCTAAGGGGAGGCAAATCCATAAGCAGGTGGTCAAACTTAAATTTAATG
ATTTTAAACAGACCACCATCGAGCATCGCAGTGACGAGGTCTCCGTGGTGATGTTCTATGAGCTACTGAGCCAAGCAATG
GCTAGGCAAGAGGGCCGTGGAATTCGGTTACTCGGGGTTTCTGTTGGACTCGCCGAGAGTAAAGACACGCTTTCGCCGCT
CATGGTACGCGAAACGAAGCAGTTGGATTTTGTGTTTTAG

Upstream 100 bases:

>100_bases
GCGCTTACAATCCAAGCGCAAACAGCACCGTTGCAAATTGATAAGTGACACTTGATTACTGTTTTTATATACAGTATTTT
GAGTGTCGGAGGAATGCAAG

Downstream 100 bases:

>100_bases
TGTCAATCTAATCAGAGCGGATCTGGCTCCGCGCCAATCTAACCTAGTTTAGTTTAGATAACGCGATAATCAGCCTTACG
CAGTGCGCAAATAGAAGCCA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSRVQRGVISTCNYEARKFGVRSAMATGYALKLCPDLILVPGRMQVYK
EVSQQIRAIFCRYTELIEPLSLDEAYLDVSDCKLFKGSATLIAEAIRRDILAETGLTASAGVAPIKFLAKVASDLNKPNG
QCVIPPDEVAEFVKSLSLRKIPGVGKVTAEKLSSLGLNTCADVQAYPKQELIARFGKFGTVLVERAHGIDERGISVSRER
KSVGVETTLAQDIYTLEQCQQVMPGLIQELSSRLGRSAKGRQIHKQVVKLKFNDFKQTTIEHRSDEVSVVMFYELLSQAM
ARQEGRGIRLLGVSVGLAESKDTLSPLMVRETKQLDFVF

Sequences:

>Translated_359_residues
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSRVQRGVISTCNYEARKFGVRSAMATGYALKLCPDLILVPGRMQVYK
EVSQQIRAIFCRYTELIEPLSLDEAYLDVSDCKLFKGSATLIAEAIRRDILAETGLTASAGVAPIKFLAKVASDLNKPNG
QCVIPPDEVAEFVKSLSLRKIPGVGKVTAEKLSSLGLNTCADVQAYPKQELIARFGKFGTVLVERAHGIDERGISVSRER
KSVGVETTLAQDIYTLEQCQQVMPGLIQELSSRLGRSAKGRQIHKQVVKLKFNDFKQTTIEHRSDEVSVVMFYELLSQAM
ARQEGRGIRLLGVSVGLAESKDTLSPLMVRETKQLDFVF
>Mature_359_residues
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSRVQRGVISTCNYEARKFGVRSAMATGYALKLCPDLILVPGRMQVYK
EVSQQIRAIFCRYTELIEPLSLDEAYLDVSDCKLFKGSATLIAEAIRRDILAETGLTASAGVAPIKFLAKVASDLNKPNG
QCVIPPDEVAEFVKSLSLRKIPGVGKVTAEKLSSLGLNTCADVQAYPKQELIARFGKFGTVLVERAHGIDERGISVSRER
KSVGVETTLAQDIYTLEQCQQVMPGLIQELSSRLGRSAKGRQIHKQVVKLKFNDFKQTTIEHRSDEVSVVMFYELLSQAM
ARQEGRGIRLLGVSVGLAESKDTLSPLMVRETKQLDFVF

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI84043967, Length=334, Percent_Identity=30.2395209580838, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI7706681, Length=335, Percent_Identity=30.1492537313433, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI154350220, Length=253, Percent_Identity=33.596837944664, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=48.5981308411215, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI5729982, Length=144, Percent_Identity=37.5, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786425, Length=355, Percent_Identity=57.4647887323944, Blast_Score=387, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI193205700, Length=394, Percent_Identity=31.7258883248731, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17537959, Length=285, Percent_Identity=28.7719298245614, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI193205702, Length=332, Percent_Identity=28.3132530120482, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI115534089, Length=351, Percent_Identity=24.5014245014245, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=207, Percent_Identity=31.4009661835749, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19923006, Length=323, Percent_Identity=31.2693498452012, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI21355641, Length=284, Percent_Identity=30.9859154929577, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24644984, Length=284, Percent_Identity=30.9859154929577, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24668444, Length=118, Percent_Identity=38.135593220339, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_SHESA (A0KTR5)

Other databases:

- EMBL:   CP000469
- RefSeq:   YP_868590.1
- ProteinModelPortal:   A0KTR5
- SMR:   A0KTR5
- STRING:   A0KTR5
- GeneID:   4478875
- GenomeReviews:   CP000469_GR
- KEGG:   shn:Shewana3_0949
- NMPDR:   fig|94122.5.peg.1075
- eggNOG:   COG0389
- HOGENOM:   HBG734504
- OMA:   QAMARQE
- PhylomeDB:   A0KTR5
- ProtClustDB:   PRK02406
- BioCyc:   SSP94122:SHEWANA3_0949-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 39801; Mature: 39801

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSRVQRGVISTCNYEARKFGVRSAMATG
CCEEEEECCHHHEEHHHHHHCHHHCCCEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHCC
YALKLCPDLILVPGRMQVYKEVSQQIRAIFCRYTELIEPLSLDEAYLDVSDCKLFKGSAT
HHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHEECCHHH
LIAEAIRRDILAETGLTASAGVAPIKFLAKVASDLNKPNGQCVIPPDEVAEFVKSLSLRK
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHC
IPGVGKVTAEKLSSLGLNTCADVQAYPKQELIARFGKFGTVLVERAHGIDERGISVSRER
CCCCCHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHH
KSVGVETTLAQDIYTLEQCQQVMPGLIQELSSRLGRSAKGRQIHKQVVKLKFNDFKQTTI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
EHRSDEVSVVMFYELLSQAMARQEGRGIRLLGVSVGLAESKDTLSPLMVRETKQLDFVF
HHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSRVQRGVISTCNYEARKFGVRSAMATG
CCEEEEECCHHHEEHHHHHHCHHHCCCEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHCC
YALKLCPDLILVPGRMQVYKEVSQQIRAIFCRYTELIEPLSLDEAYLDVSDCKLFKGSAT
HHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHEECCHHH
LIAEAIRRDILAETGLTASAGVAPIKFLAKVASDLNKPNGQCVIPPDEVAEFVKSLSLRK
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHC
IPGVGKVTAEKLSSLGLNTCADVQAYPKQELIARFGKFGTVLVERAHGIDERGISVSRER
CCCCCHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHH
KSVGVETTLAQDIYTLEQCQQVMPGLIQELSSRLGRSAKGRQIHKQVVKLKFNDFKQTTI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
EHRSDEVSVVMFYELLSQAMARQEGRGIRLLGVSVGLAESKDTLSPLMVRETKQLDFVF
HHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA