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The map label for this gene is ywbI [H]

Identifier: 117919336

GI number: 117919336

Start: 1030101

End: 1030991

Strand: Reverse

Name: ywbI [H]

Synonym: Shewana3_0884

Alternate gene names: 117919336

Gene position: 1030991-1030101 (Counterclockwise)

Preceding gene: 117919342

Following gene: 117919334

Centisome position: 20.74

GC content: 53.54

Gene sequence:

>891_bases
ATGGATCTTAAAGTGCTGCGTTATTTTATCGAGATCATCGATGCTGGCGGTTTCGGTAAGGCCAGCGAAAAGGTTCACCT
CACCCAACCCGCCCTCTCCAAGGCGCTGCGCCAATTAGAGGAAGAACTCGATCTGGTACTACTCGAGCGCGGCAAACGTG
GCACTCAGGTTAAGCTCACCCAAGCGGGAGAAGTGGTCTATCGCCATGGTAAGGAGTTACTCGCAGGGCGACAACGCATG
CTGGCCGAACTCAGCGCCCAGCGCAGTTTAACCGCAGGCGAATTAAAACTCGGTCTCGCGCCACTCGGCAGTGCTGAAAT
TTTTGCCCCTATCATTGCCAAATATCGCCAGCAATATCCGCAAATTGATATGCACCTGCTGGTGCGCGGCGGCGTGGAGC
AAACCTTAGCGATTCAAAAGGGGGAAATTGAACTGGCCACCGGGATTATCAACTTCGACGATGGTTACCACGGCATTCGG
GTGTTTAACGATCCCATGGTGGTGGTGCTGCCCAAGGAGAATCCCCTCACCTCACAAGCTATGCTGTCGATCCACGACTT
AGTCGACGAGCCGCAAGTGATGTTTGAAACCGAATACACCTTGTATCAACTGGTGTTAACCGCTTGCCAACACGCCGGAT
TTACTCCTAAAAACATCACTCGAGTCAGCCAAGCCGACTTCGGGATCGCCCTTGTGGCGGCGGGCACGGGCGTGATGATA
CTGCCGCGCTCTATCGCGCGGCGTTACAGCGTATCTGGGGTGGTGAATATTCCATTGGCGAGCGATGAACTGCGCTGGGA
GTTATCACTGTTTTGGCGCAAAGAACAGGTATTGTCCTTTGCGGCACAGGCGATGATTGCGTTAGTGGAGAAACACTTAA
CGCAAAAGTAG

Upstream 100 bases:

>100_bases
AAAGTTGCTATGGGAATATTTTAGGCTTGCCTATTCAATAAAAAAAATGAATATTAAGCATGTAATCCATGAATTTTAAG
AATGTATTATCGAGGCGAGA

Downstream 100 bases:

>100_bases
CTCACTACCAAGGCACGACTAAGCTAAAGCGCACTAAGGTATCGTTATCCCAAGGCAGAATGGGCAAGTAGTCGGGTGAG
TGCACACTCTCCTTGGCATA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDLKVLRYFIEIIDAGGFGKASEKVHLTQPALSKALRQLEEELDLVLLERGKRGTQVKLTQAGEVVYRHGKELLAGRQRM
LAELSAQRSLTAGELKLGLAPLGSAEIFAPIIAKYRQQYPQIDMHLLVRGGVEQTLAIQKGEIELATGIINFDDGYHGIR
VFNDPMVVVLPKENPLTSQAMLSIHDLVDEPQVMFETEYTLYQLVLTACQHAGFTPKNITRVSQADFGIALVAAGTGVMI
LPRSIARRYSVSGVVNIPLASDELRWELSLFWRKEQVLSFAAQAMIALVEKHLTQK

Sequences:

>Translated_296_residues
MDLKVLRYFIEIIDAGGFGKASEKVHLTQPALSKALRQLEEELDLVLLERGKRGTQVKLTQAGEVVYRHGKELLAGRQRM
LAELSAQRSLTAGELKLGLAPLGSAEIFAPIIAKYRQQYPQIDMHLLVRGGVEQTLAIQKGEIELATGIINFDDGYHGIR
VFNDPMVVVLPKENPLTSQAMLSIHDLVDEPQVMFETEYTLYQLVLTACQHAGFTPKNITRVSQADFGIALVAAGTGVMI
LPRSIARRYSVSGVVNIPLASDELRWELSLFWRKEQVLSFAAQAMIALVEKHLTQK
>Mature_296_residues
MDLKVLRYFIEIIDAGGFGKASEKVHLTQPALSKALRQLEEELDLVLLERGKRGTQVKLTQAGEVVYRHGKELLAGRQRM
LAELSAQRSLTAGELKLGLAPLGSAEIFAPIIAKYRQQYPQIDMHLLVRGGVEQTLAIQKGEIELATGIINFDDGYHGIR
VFNDPMVVVLPKENPLTSQAMLSIHDLVDEPQVMFETEYTLYQLVLTACQHAGFTPKNITRVSQADFGIALVAAGTGVMI
LPRSIARRYSVSGVVNIPLASDELRWELSLFWRKEQVLSFAAQAMIALVEKHLTQK

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=277, Percent_Identity=26.7148014440433, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI2367136, Length=293, Percent_Identity=25.5972696245734, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI157672245, Length=287, Percent_Identity=25.7839721254355, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=27.6450511945392, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788887, Length=302, Percent_Identity=27.4834437086093, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=23.1833910034602, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788297, Length=263, Percent_Identity=28.5171102661597, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789506, Length=287, Percent_Identity=22.6480836236934, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787530, Length=245, Percent_Identity=24.0816326530612, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787806, Length=287, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790262, Length=256, Percent_Identity=22.265625, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=140, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789204, Length=257, Percent_Identity=22.568093385214, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87081904, Length=177, Percent_Identity=25.9887005649718, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=250, Percent_Identity=23.6, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789440, Length=126, Percent_Identity=30.952380952381, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1786401, Length=122, Percent_Identity=27.8688524590164, Blast_Score=61, Evalue=9e-11,
Organism=Escherichia coli, GI1789639, Length=171, Percent_Identity=25.7309941520468, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32875; Mature: 32875

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKVLRYFIEIIDAGGFGKASEKVHLTQPALSKALRQLEEELDLVLLERGKRGTQVKLT
CCHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEE
QAGEVVYRHGKELLAGRQRMLAELSAQRSLTAGELKLGLAPLGSAEIFAPIIAKYRQQYP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCC
QIDMHLLVRGGVEQTLAIQKGEIELATGIINFDDGYHGIRVFNDPMVVVLPKENPLTSQA
CCCEEEEEECCCHHHHEEECCCEEEEEEEEECCCCCCCEEEECCCEEEEECCCCCCHHHH
MLSIHDLVDEPQVMFETEYTLYQLVLTACQHAGFTPKNITRVSQADFGIALVAAGTGVMI
HHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEECCCCEEE
LPRSIARRYSVSGVVNIPLASDELRWELSLFWRKEQVLSFAAQAMIALVEKHLTQK
ECHHHHHHHCCCCEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLKVLRYFIEIIDAGGFGKASEKVHLTQPALSKALRQLEEELDLVLLERGKRGTQVKLT
CCHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEE
QAGEVVYRHGKELLAGRQRMLAELSAQRSLTAGELKLGLAPLGSAEIFAPIIAKYRQQYP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCC
QIDMHLLVRGGVEQTLAIQKGEIELATGIINFDDGYHGIRVFNDPMVVVLPKENPLTSQA
CCCEEEEEECCCHHHHEEECCCEEEEEEEEECCCCCCCEEEECCCEEEEECCCCCCHHHH
MLSIHDLVDEPQVMFETEYTLYQLVLTACQHAGFTPKNITRVSQADFGIALVAAGTGVMI
HHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEECCCCEEE
LPRSIARRYSVSGVVNIPLASDELRWELSLFWRKEQVLSFAAQAMIALVEKHLTQK
ECHHHHHHHCCCCEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]