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The map label for this gene is cysH [H]

Identifier: 117919309

GI number: 117919309

Start: 996944

End: 997741

Strand: Direct

Name: cysH [H]

Synonym: Shewana3_0857

Alternate gene names: 117919309

Gene position: 996944-997741 (Clockwise)

Preceding gene: 117919308

Following gene: 117919310

Centisome position: 20.05

GC content: 50.5

Gene sequence:

>798_bases
ATGGCTGATCTTGATTCTGGGGTAACGGGTTCTGGCTTGCCGAACGCGTTGCAGAGCGTGGTAAGTCACAGCGAACTTAA
AGCGCTGCTGACGGCGCCTAAGGATGTGCAGCAAGCGGAACTGGAGCGCATTAATCGCTTCTTGGCCGGATTGACGGCTC
AAGAGCGAGTGCTCTGGGGCTTAGCCTATCTGCCGGGTAATCACGCGCTGTCATCCAGTTTTGGGATCCAGGCGGCGGTG
ATGCTGCATATGGTGAGTCAGGTGCAATCGGATATTCCGGTTATCTTAACGGATACTGGCTATCTCTTTCCTGAGACATA
TCAGTTTATTGACCAGCTTACCGAGCGTTTATCCTTAAACCTCAAGGTTTACCAAGCGCCAATGACCTCGGCATGGCAGG
AGGCGCGTTTTGGCAAGTTGTGGGAGCAGGGCTTAGATGGGCTCGAGCGTTACAATCGACTGAATAAAGTGGAGCCGATG
CAACGTGCTTTGGCGGAACTTGAAGTAGGTACTTGGTTCGCGGGACTACGCCGCAGCCAGTCGAGCACACGCGAAGAGTT
ACCGATATTGGCTATCCATGGCACTCGCTTTAAGTTGTTGCCGATTATCGAGTGGTCGAACAAAGATGTGCATCTGTATC
TGACGCAATTTGACTTGCCTTACCATCCTCTATGGGATCAAGGTTATGTTTCTGTTGGGGATACCCACTCGAGTAAACCC
TTAGAATTAGGGATGACTGAAGAAGAAACCCGCTTTAATGGCTTAAAACGCGAATGCGGTTTGCATTACGAAATATAA

Upstream 100 bases:

>100_bases
GCCCGCTACGCGGTTGAGCGTAATGCAGGCGAAACCTTTGGTAACTTCACCGTCCGCACGGGCGTGGTGAAGGCGGTTAT
CGATGCCGCTAAGGATTTCC

Downstream 100 bases:

>100_bases
CCATCTATCTGATTTAATAGATAAATGCCACAGTATTCCCTGTGGCATTTTTTATTTTATGCCGCCAAAAGAATACTTTG
CTTAATTTTGCAGCGGTTTG

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MADLDSGVTGSGLPNALQSVVSHSELKALLTAPKDVQQAELERINRFLAGLTAQERVLWGLAYLPGNHALSSSFGIQAAV
MLHMVSQVQSDIPVILTDTGYLFPETYQFIDQLTERLSLNLKVYQAPMTSAWQEARFGKLWEQGLDGLERYNRLNKVEPM
QRALAELEVGTWFAGLRRSQSSTREELPILAIHGTRFKLLPIIEWSNKDVHLYLTQFDLPYHPLWDQGYVSVGDTHSSKP
LELGMTEEETRFNGLKRECGLHYEI

Sequences:

>Translated_265_residues
MADLDSGVTGSGLPNALQSVVSHSELKALLTAPKDVQQAELERINRFLAGLTAQERVLWGLAYLPGNHALSSSFGIQAAV
MLHMVSQVQSDIPVILTDTGYLFPETYQFIDQLTERLSLNLKVYQAPMTSAWQEARFGKLWEQGLDGLERYNRLNKVEPM
QRALAELEVGTWFAGLRRSQSSTREELPILAIHGTRFKLLPIIEWSNKDVHLYLTQFDLPYHPLWDQGYVSVGDTHSSKP
LELGMTEEETRFNGLKRECGLHYEI
>Mature_264_residues
ADLDSGVTGSGLPNALQSVVSHSELKALLTAPKDVQQAELERINRFLAGLTAQERVLWGLAYLPGNHALSSSFGIQAAVM
LHMVSQVQSDIPVILTDTGYLFPETYQFIDQLTERLSLNLKVYQAPMTSAWQEARFGKLWEQGLDGLERYNRLNKVEPMQ
RALAELEVGTWFAGLRRSQSSTREELPILAIHGTRFKLLPIIEWSNKDVHLYLTQFDLPYHPLWDQGYVSVGDTHSSKPL
ELGMTEEETRFNGLKRECGLHYEI

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=242, Percent_Identity=61.9834710743802, Blast_Score=313, Evalue=6e-87,
Organism=Saccharomyces cerevisiae, GI6325425, Length=244, Percent_Identity=32.3770491803279, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 29928; Mature: 29797

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLDSGVTGSGLPNALQSVVSHSELKALLTAPKDVQQAELERINRFLAGLTAQERVLWG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
LAYLPGNHALSSSFGIQAAVMLHMVSQVQSDIPVILTDTGYLFPETYQFIDQLTERLSLN
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCC
LKVYQAPMTSAWQEARFGKLWEQGLDGLERYNRLNKVEPMQRALAELEVGTWFAGLRRSQ
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
SSTREELPILAIHGTRFKLLPIIEWSNKDVHLYLTQFDLPYHPLWDQGYVSVGDTHSSKP
CCHHHCCCEEEEECCCEEEEEEEEECCCCEEEEEEEECCCCCCCCCCCCEEECCCCCCCC
LELGMTEEETRFNGLKRECGLHYEI
EEECCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ADLDSGVTGSGLPNALQSVVSHSELKALLTAPKDVQQAELERINRFLAGLTAQERVLWG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
LAYLPGNHALSSSFGIQAAVMLHMVSQVQSDIPVILTDTGYLFPETYQFIDQLTERLSLN
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCC
LKVYQAPMTSAWQEARFGKLWEQGLDGLERYNRLNKVEPMQRALAELEVGTWFAGLRRSQ
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
SSTREELPILAIHGTRFKLLPIIEWSNKDVHLYLTQFDLPYHPLWDQGYVSVGDTHSSKP
CCHHHCCCEEEEECCCEEEEEEEEECCCCEEEEEEEECCCCCCCCCCCCEEECCCCCCCC
LELGMTEEETRFNGLKRECGLHYEI
EEECCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]