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The map label for this gene is mtgA [H]

Identifier: 117919310

GI number: 117919310

Start: 998418

End: 999203

Strand: Direct

Name: mtgA [H]

Synonym: Shewana3_0858

Alternate gene names: 117919310

Gene position: 998418-999203 (Clockwise)

Preceding gene: 117919309

Following gene: 117919311

Centisome position: 20.08

GC content: 49.36

Gene sequence:

>786_bases
ATGACCGCCCCTATGTATGCCATGCGCGATCATGTCAATCGTCCTCAAGGGAATAAATCTAATCGTCCAGCACAAAAGCC
CAAAGCGCGTGGCCTTAAGCGAATAGTCGCTTGGCTCGTTAAACTCATCTTAGGCTTATTACTCGCCTCCATTTTAAGCG
TGGTGCTACTGCGTTTTATTGACCCGCCGATGTGGACTTGGCGGATTGAACGGGCATTATTCCCGCCCGCACCAGTGACA
GAAGTGCGACATCAATGGCGCTCACTCGAGCAAATCTCCCCTGAATTACAATTAGCCGTGATTGCCGCAGAGGATCAAAA
GTTTGCCAGCCACACGGGGTTTGATTTAGCCGCGATAAGTTCGGCCATTGAATACAATCAAAAGGGCAACAAGGTTCGTG
GTGCGAGTACCTTAAGTCAGCAAGCGGCGAAAAACCTGTTTATGTGGTCGAGCCGCAGTTTTATCCGCAAGGGAATTGAG
GCCTGGTTTACCCTATTAATGGAATTGATTTGGGATAAGTCGCGCATACTCGAAGTGTATCTGAATATCGTCGAATTCGG
CCCCGGAATATATGGCGCCGAAGCCGCATCGAAACATTATTTTGGTAAGAGTGCCGCCAAATTAACCCGTTATGAGGCGT
CATTATTAGCGGCGGTATTGCCTAATCCTTGGCGTTATAAAGTCTCGCCGCCTTCACCCTATGTTGAGCAGCGCTCCGCT
TGGATCCGTAAGCAAATGCGCCAGTTAGGGGAAGTGACTCTTAACCGTGTTCATCAGGCCGATTAA

Upstream 100 bases:

>100_bases
TGACAATATTATCATCAACTTACACTGTGCTATTTTATGCTGAGTGGCTAATGCCGCCGCATATGGCCCCTTTGATGGAA
TTATTGATGAGGATTACTGG

Downstream 100 bases:

>100_bases
CGGATAAATAAGGCGATAACTTTCGTCTTATTAATATGCCATGCGCTTTATCGTTAATATGAACTTTATCCTCAAGATGA
ATTAGGCTCTGAATGTAAAT

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTAPMYAMRDHVNRPQGNKSNRPAQKPKARGLKRIVAWLVKLILGLLLASILSVVLLRFIDPPMWTWRIERALFPPAPVT
EVRHQWRSLEQISPELQLAVIAAEDQKFASHTGFDLAAISSAIEYNQKGNKVRGASTLSQQAAKNLFMWSSRSFIRKGIE
AWFTLLMELIWDKSRILEVYLNIVEFGPGIYGAEAASKHYFGKSAAKLTRYEASLLAAVLPNPWRYKVSPPSPYVEQRSA
WIRKQMRQLGEVTLNRVHQAD

Sequences:

>Translated_261_residues
MTAPMYAMRDHVNRPQGNKSNRPAQKPKARGLKRIVAWLVKLILGLLLASILSVVLLRFIDPPMWTWRIERALFPPAPVT
EVRHQWRSLEQISPELQLAVIAAEDQKFASHTGFDLAAISSAIEYNQKGNKVRGASTLSQQAAKNLFMWSSRSFIRKGIE
AWFTLLMELIWDKSRILEVYLNIVEFGPGIYGAEAASKHYFGKSAAKLTRYEASLLAAVLPNPWRYKVSPPSPYVEQRSA
WIRKQMRQLGEVTLNRVHQAD
>Mature_260_residues
TAPMYAMRDHVNRPQGNKSNRPAQKPKARGLKRIVAWLVKLILGLLLASILSVVLLRFIDPPMWTWRIERALFPPAPVTE
VRHQWRSLEQISPELQLAVIAAEDQKFASHTGFDLAAISSAIEYNQKGNKVRGASTLSQQAAKNLFMWSSRSFIRKGIEA
WFTLLMELIWDKSRILEVYLNIVEFGPGIYGAEAASKHYFGKSAAKLTRYEASLLAAVLPNPWRYKVSPPSPYVEQRSAW
IRKQMRQLGEVTLNRVHQAD

Specific function: Cell wall formation [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family [H]

Homologues:

Organism=Escherichia coli, GI1789601, Length=178, Percent_Identity=60.1123595505618, Blast_Score=217, Evalue=7e-58,
Organism=Escherichia coli, GI87082258, Length=212, Percent_Identity=31.1320754716981, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786343, Length=137, Percent_Identity=40.8759124087591, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788867, Length=140, Percent_Identity=36.4285714285714, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001264
- InterPro:   IPR011812 [H]

Pfam domain/function: PF00912 Transgly [H]

EC number: 2.4.2.- [C]

Molecular weight: Translated: 29709; Mature: 29578

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPMYAMRDHVNRPQGNKSNRPAQKPKARGLKRIVAWLVKLILGLLLASILSVVLLRFI
CCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPPMWTWRIERALFPPAPVTEVRHQWRSLEQISPELQLAVIAAEDQKFASHTGFDLAAIS
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHCCCCHHHHHH
SAIEYNQKGNKVRGASTLSQQAAKNLFMWSSRSFIRKGIEAWFTLLMELIWDKSRILEVY
HHHHHCCCCCEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNIVEFGPGIYGAEAASKHYFGKSAAKLTRYEASLLAAVLPNPWRYKVSPPSPYVEQRSA
HHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHH
WIRKQMRQLGEVTLNRVHQAD
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAPMYAMRDHVNRPQGNKSNRPAQKPKARGLKRIVAWLVKLILGLLLASILSVVLLRFI
CCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPPMWTWRIERALFPPAPVTEVRHQWRSLEQISPELQLAVIAAEDQKFASHTGFDLAAIS
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHCCCCHHHHHH
SAIEYNQKGNKVRGASTLSQQAAKNLFMWSSRSFIRKGIEAWFTLLMELIWDKSRILEVY
HHHHHCCCCCEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNIVEFGPGIYGAEAASKHYFGKSAAKLTRYEASLLAAVLPNPWRYKVSPPSPYVEQRSA
HHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHH
WIRKQMRQLGEVTLNRVHQAD
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]