Click here to switch to the map view.

The map label for this gene is putA [H]

Identifier: 117919271

GI number: 117919271

Start: 947610

End: 950804

Strand: Reverse

Name: putA [H]

Synonym: Shewana3_0819

Alternate gene names: 117919271

Gene position: 950804-947610 (Counterclockwise)

Preceding gene: 117919272

Following gene: 117919269

Centisome position: 19.12

GC content: 51.3

Gene sequence:

>3195_bases
ATGGAAGCGATTACTATGTTCAAAGCGAGTGAAGTGCTGGCAGGCCGCTACGATTCTGCCAATCTCGACGAACTGTTCAA
AGCCGTCACCGACAACTACATTGTCGATGAAGAACAATACTTGTCAGAGCTAATCAAACTAGTGCCCTCCAGTGATGAAG
CCATCGAGCGCGTCACTCGTCGTGCCCACGAACTGGTCAACAAAGTTCGTCAATTCGATAAGAAAGGTTTAATGGTTGGC
ATCGACGCCTTCCTGCAGCAATACAGCTTAGAAACACAGGAAGGGATTATCCTGATGTGTTTAGCCGAAGCCCTGCTGCG
TATTCCCGATGCGGCCACCGCCGACGCCTTGATTGAAGATAAACTCTCAGGCGCAAAATGGGATGAACACTTAAGCAAGA
GCGATTCGGTACTGGTTAACGCCTCCACTTGGGGCTTAATGCTCACTGGCAAAATCGTCAAACTCGATAAAAAAATCGAT
GGTACGCCAAGCAACCTGTTAAGCCGTTTAGTAAACCGTTTAGGTGAGCCTGTGATCCGCCAAGCCATGATGGCGGCGAT
GAAGATCATGGGTAAGCAGTTCGTTCTCGGTCGCACCATGAAAGAAGCGCTCAAGAACAGTGAAGACAAGCGTAAATTAG
GTTATACCCACTCCTACGATATGCTGGGTGAAGCCGCGCTGACGCGTAAGGATGCCGAAAAATACTTTAACGATTATGCC
AATGCGATTACCGAGTTAGGCGCGCAAAGCTATAACGAAAACGAATCTCCACGCCCAACCATTTCGATCAAGCTGTCGGC
ACTGCACCCACGTTACGAAGTCGCTAACGAAGACCGTGTACTGACCGAGCTGTATGACACAGTTATTCGCCTGATTAAGT
TAGCCCGTGGCTTAAATATCGGTATTTCTATCGACGCCGAAGAAGTTGACCGCCTCGAACTGTCATTAAAACTGTTCCAA
AAGCTGTTTAACGCTGACGCCACTAAGGGTTGGGGCTTACTCGGTATCGTAGTGCAAGCTTACTCTAAGCGCGCCCTGCC
TGTACTGGTATGGTTAACCCGTCTAGCGAAAGAGCAAGGCGACGAAATTCCGGTTCGCTTAGTGAAAGGCGCTTACTGGG
ATAGTGAGCTGAAATGGGCACAACAAGCTGGCGAAGCCGCATACCCACTCTACACCCGCAAAGCAGGTACCGACGTATCT
TACTTAGCCTGTGCGCGTTACCTGTTATCTGACGCCACCCGCGGCGCGATTTACCCCCAATTTGCCAGCCACAACGCGCA
AACCGTTGCCGCGATTTCAGATATGGCGGGCGATCGTAACCACGAGTTCCAACGCCTACACGGCATGGGACAAGAGCTGT
ACGACACTATTCTGTCGGAAGCTGGCGCGAAAGCGGTACGTATCTACGCCCCAATCGGTGCCCATAAAGATCTACTGCCC
TACTTAGTGCGTCGCCTACTGGAAAACGGTGCGAACACCTCGTTCGTACACAAGCTGGTCGATCCTAAAACCCCTATCGA
GTCTTTAGTGGTTCACCCACTGAAAACCCTGACAGGCTACAAAACCCTGGCTAACAACAAAATCGTTTTACCTACCGACA
TCTTCGGTAGCGATCGCAAAAATTCCAAGGGACTCAATATGAACATCATTTCAGAAGCAGAGCCATTCTTCGCGGCCTTA
GACAAATTCAAATCGACGCAGTGGCAAGCGGGCCCTCTGGTTAATGGCCAAACCTTAACTGGCGAGCACAAAACCGTGGT
GAGCCCATTCGATACCACCCAAACTGTGGGTCAAGTGGCCTTTGCTGACAAAGCGGCTATCGAACAAGCTGTGGCCTCTG
CCGATGCGGCGTTTGCAACTTGGACTCGTACTCCGGTTGAAGTACGCGCCTCAGCCCTGCAAAAGCTTGCGGACCTGTTA
GAAGAAAACCGCGAAGAACTGATTGCTCTGTGTACCCGTGAAGCGGGCAAGAGCATTCAAGACGGTATCGATGAAGTGCG
TGAAGCCGTAGACTTCTGCCGCTACTACGCGGTGCAAGCTAAGAAGCTGATGTCAAAACCTGAACTGCTCCCTGGCCCAA
CGGGTGAATTAAACGAACTCTTCCTCCAAGGTCGCGGTGTGTTCGTCTGTATCAGCCCATGGAACTTCCCATTGGCTATC
TTCCTAGGCCAAGTATCAGCAGCCCTCGCTGCGGGTAACACTGTAGTAGCTAAACCTGCAGAGCAAACCTCTATCATTGG
TTACCGTGCAGTGCAGCTCGCACACCAAGCGGGTATTCCAACGGACGTGCTGCAATATCTACCAGGCACAGGCGCTACCG
TAGGTAACGCACTGACGGCAGATGAGCGCATCGGCGGCGTATGTTTTACCGGTTCAACGGGCACAGCCAAACTCATCAAC
CGCACACTGGCCAACCGTGAAGGCGCAATTATTCCATTAATCGCCGAAACTGGTGGTCAAAACGCTATGGTGGTTGACTC
TACTTCTCAGCCAGAACAAGTGGTTAACGATGTAGTATCTTCATCCTTCACCAGCGCGGGTCAACGCTGCTCGGCGCTGC
GTGTACTCTTCCTACAGGAAGATATTGCTGACCGCGTTATCGACGTACTCCAAGGTGCGATGGATGAGTTAGTGATTGGC
AACCCAAGTTCAGTGAAAACCGACGTAGGCCCAGTTATCGATGCGACCGCGAAGGCGAACCTTGACGCCCATATCGACCA
CATCAAGCAAGTGGGCAAGCTTATCAAGCAAATGTCCCTGCCAGCGGGCACTGAAAACGGTCACTTTGTGTCGCCAACTG
CCGTTGAAATCGACTCAATCAAAGTGCTTGAAAAAGAACACTTTGGTCCAATCCTGCACGTAATCCGTTACAAGGCATCT
GAACTTGCCCATGTGATCGATGAAATCAACAGCACAGGCTTTGGCTTAACCTTAGGTATCCACAGCCGTAACGAAGGCCA
TGCCCTCGAAGTAGCTGACAAGGTTAACGTAGGTAACGTGTACATCAACCGTAACCAAATCGGCGCAGTCGTTGGCGTAC
AGCCTTTCGGCGGCCAAGGTCTGTCAGGCACAGGTCCAAAAGCCGGTGGTCCACACTACTTAACTCGCTTCGTGACTGAA
AAGACACGCACTAACAACATCACCGCTATCGGTGGTAATGCGACCCTGTTGTCACTGGGTGATAGCGACGCCTAA

Upstream 100 bases:

>100_bases
AATCTGCGCGCGCAAAGCTTCATATTGTATACAAAATATCAAATGCGTTTCGCGCCCCCCATTTTTGTTTCAACAATAGA
GCCGAAAACAACTGGCCAAG

Downstream 100 bases:

>100_bases
GTCCTAACGACTTATTGATAAACGAAAGCCAGACTCAGTCTGGCTTTTTTATGGGCTAATGAATGTGTATACCTATATTC
AATGAGAGAAATGATCATAG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1064; Mature: 1064

Protein sequence:

>1064_residues
MEAITMFKASEVLAGRYDSANLDELFKAVTDNYIVDEEQYLSELIKLVPSSDEAIERVTRRAHELVNKVRQFDKKGLMVG
IDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIEDKLSGAKWDEHLSKSDSVLVNASTWGLMLTGKIVKLDKKID
GTPSNLLSRLVNRLGEPVIRQAMMAAMKIMGKQFVLGRTMKEALKNSEDKRKLGYTHSYDMLGEAALTRKDAEKYFNDYA
NAITELGAQSYNENESPRPTISIKLSALHPRYEVANEDRVLTELYDTVIRLIKLARGLNIGISIDAEEVDRLELSLKLFQ
KLFNADATKGWGLLGIVVQAYSKRALPVLVWLTRLAKEQGDEIPVRLVKGAYWDSELKWAQQAGEAAYPLYTRKAGTDVS
YLACARYLLSDATRGAIYPQFASHNAQTVAAISDMAGDRNHEFQRLHGMGQELYDTILSEAGAKAVRIYAPIGAHKDLLP
YLVRRLLENGANTSFVHKLVDPKTPIESLVVHPLKTLTGYKTLANNKIVLPTDIFGSDRKNSKGLNMNIISEAEPFFAAL
DKFKSTQWQAGPLVNGQTLTGEHKTVVSPFDTTQTVGQVAFADKAAIEQAVASADAAFATWTRTPVEVRASALQKLADLL
EENREELIALCTREAGKSIQDGIDEVREAVDFCRYYAVQAKKLMSKPELLPGPTGELNELFLQGRGVFVCISPWNFPLAI
FLGQVSAALAAGNTVVAKPAEQTSIIGYRAVQLAHQAGIPTDVLQYLPGTGATVGNALTADERIGGVCFTGSTGTAKLIN
RTLANREGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVSSSFTSAGQRCSALRVLFLQEDIADRVIDVLQGAMDELVIG
NPSSVKTDVGPVIDATAKANLDAHIDHIKQVGKLIKQMSLPAGTENGHFVSPTAVEIDSIKVLEKEHFGPILHVIRYKAS
ELAHVIDEINSTGFGLTLGIHSRNEGHALEVADKVNVGNVYINRNQIGAVVGVQPFGGQGLSGTGPKAGGPHYLTRFVTE
KTRTNNITAIGGNATLLSLGDSDA

Sequences:

>Translated_1064_residues
MEAITMFKASEVLAGRYDSANLDELFKAVTDNYIVDEEQYLSELIKLVPSSDEAIERVTRRAHELVNKVRQFDKKGLMVG
IDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIEDKLSGAKWDEHLSKSDSVLVNASTWGLMLTGKIVKLDKKID
GTPSNLLSRLVNRLGEPVIRQAMMAAMKIMGKQFVLGRTMKEALKNSEDKRKLGYTHSYDMLGEAALTRKDAEKYFNDYA
NAITELGAQSYNENESPRPTISIKLSALHPRYEVANEDRVLTELYDTVIRLIKLARGLNIGISIDAEEVDRLELSLKLFQ
KLFNADATKGWGLLGIVVQAYSKRALPVLVWLTRLAKEQGDEIPVRLVKGAYWDSELKWAQQAGEAAYPLYTRKAGTDVS
YLACARYLLSDATRGAIYPQFASHNAQTVAAISDMAGDRNHEFQRLHGMGQELYDTILSEAGAKAVRIYAPIGAHKDLLP
YLVRRLLENGANTSFVHKLVDPKTPIESLVVHPLKTLTGYKTLANNKIVLPTDIFGSDRKNSKGLNMNIISEAEPFFAAL
DKFKSTQWQAGPLVNGQTLTGEHKTVVSPFDTTQTVGQVAFADKAAIEQAVASADAAFATWTRTPVEVRASALQKLADLL
EENREELIALCTREAGKSIQDGIDEVREAVDFCRYYAVQAKKLMSKPELLPGPTGELNELFLQGRGVFVCISPWNFPLAI
FLGQVSAALAAGNTVVAKPAEQTSIIGYRAVQLAHQAGIPTDVLQYLPGTGATVGNALTADERIGGVCFTGSTGTAKLIN
RTLANREGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVSSSFTSAGQRCSALRVLFLQEDIADRVIDVLQGAMDELVIG
NPSSVKTDVGPVIDATAKANLDAHIDHIKQVGKLIKQMSLPAGTENGHFVSPTAVEIDSIKVLEKEHFGPILHVIRYKAS
ELAHVIDEINSTGFGLTLGIHSRNEGHALEVADKVNVGNVYINRNQIGAVVGVQPFGGQGLSGTGPKAGGPHYLTRFVTE
KTRTNNITAIGGNATLLSLGDSDA
>Mature_1064_residues
MEAITMFKASEVLAGRYDSANLDELFKAVTDNYIVDEEQYLSELIKLVPSSDEAIERVTRRAHELVNKVRQFDKKGLMVG
IDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIEDKLSGAKWDEHLSKSDSVLVNASTWGLMLTGKIVKLDKKID
GTPSNLLSRLVNRLGEPVIRQAMMAAMKIMGKQFVLGRTMKEALKNSEDKRKLGYTHSYDMLGEAALTRKDAEKYFNDYA
NAITELGAQSYNENESPRPTISIKLSALHPRYEVANEDRVLTELYDTVIRLIKLARGLNIGISIDAEEVDRLELSLKLFQ
KLFNADATKGWGLLGIVVQAYSKRALPVLVWLTRLAKEQGDEIPVRLVKGAYWDSELKWAQQAGEAAYPLYTRKAGTDVS
YLACARYLLSDATRGAIYPQFASHNAQTVAAISDMAGDRNHEFQRLHGMGQELYDTILSEAGAKAVRIYAPIGAHKDLLP
YLVRRLLENGANTSFVHKLVDPKTPIESLVVHPLKTLTGYKTLANNKIVLPTDIFGSDRKNSKGLNMNIISEAEPFFAAL
DKFKSTQWQAGPLVNGQTLTGEHKTVVSPFDTTQTVGQVAFADKAAIEQAVASADAAFATWTRTPVEVRASALQKLADLL
EENREELIALCTREAGKSIQDGIDEVREAVDFCRYYAVQAKKLMSKPELLPGPTGELNELFLQGRGVFVCISPWNFPLAI
FLGQVSAALAAGNTVVAKPAEQTSIIGYRAVQLAHQAGIPTDVLQYLPGTGATVGNALTADERIGGVCFTGSTGTAKLIN
RTLANREGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVSSSFTSAGQRCSALRVLFLQEDIADRVIDVLQGAMDELVIG
NPSSVKTDVGPVIDATAKANLDAHIDHIKQVGKLIKQMSLPAGTENGHFVSPTAVEIDSIKVLEKEHFGPILHVIRYKAS
ELAHVIDEINSTGFGLTLGIHSRNEGHALEVADKVNVGNVYINRNQIGAVVGVQPFGGQGLSGTGPKAGGPHYLTRFVTE
KTRTNNITAIGGNATLLSLGDSDA

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=490, Percent_Identity=31.0204081632653, Blast_Score=209, Evalue=2e-53,
Organism=Homo sapiens, GI25777734, Length=490, Percent_Identity=31.0204081632653, Blast_Score=209, Evalue=2e-53,
Organism=Homo sapiens, GI238859541, Length=490, Percent_Identity=31.0204081632653, Blast_Score=208, Evalue=3e-53,
Organism=Homo sapiens, GI153266822, Length=490, Percent_Identity=29.7959183673469, Blast_Score=198, Evalue=3e-50,
Organism=Homo sapiens, GI25777732, Length=455, Percent_Identity=31.6483516483516, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI21361176, Length=498, Percent_Identity=29.3172690763052, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI25777724, Length=479, Percent_Identity=30.062630480167, Blast_Score=180, Evalue=6e-45,
Organism=Homo sapiens, GI12007648, Length=464, Percent_Identity=30.1724137931034, Blast_Score=180, Evalue=8e-45,
Organism=Homo sapiens, GI25777730, Length=478, Percent_Identity=30.1255230125523, Blast_Score=177, Evalue=4e-44,
Organism=Homo sapiens, GI238814322, Length=490, Percent_Identity=29.7959183673469, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI21614513, Length=434, Percent_Identity=30.4147465437788, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI25777728, Length=410, Percent_Identity=30, Blast_Score=160, Evalue=5e-39,
Organism=Homo sapiens, GI4507229, Length=431, Percent_Identity=29.4663573085847, Blast_Score=154, Evalue=5e-37,
Organism=Homo sapiens, GI188035924, Length=480, Percent_Identity=27.5, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI310128103, Length=461, Percent_Identity=27.9826464208243, Blast_Score=148, Evalue=3e-35,
Organism=Homo sapiens, GI310128093, Length=461, Percent_Identity=27.9826464208243, Blast_Score=148, Evalue=3e-35,
Organism=Homo sapiens, GI25952152, Length=454, Percent_Identity=28.8546255506608, Blast_Score=146, Evalue=8e-35,
Organism=Homo sapiens, GI25777721, Length=444, Percent_Identity=28.3783783783784, Blast_Score=144, Evalue=7e-34,
Organism=Homo sapiens, GI115387104, Length=445, Percent_Identity=25.3932584269663, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI25777726, Length=479, Percent_Identity=27.348643006263, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI11095441, Length=420, Percent_Identity=28.0952380952381, Blast_Score=134, Evalue=4e-31,
Organism=Homo sapiens, GI310128091, Length=416, Percent_Identity=27.6442307692308, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI206597441, Length=445, Percent_Identity=24.4943820224719, Blast_Score=114, Evalue=5e-25,
Organism=Homo sapiens, GI206597439, Length=445, Percent_Identity=24.4943820224719, Blast_Score=114, Evalue=5e-25,
Organism=Homo sapiens, GI22907049, Length=445, Percent_Identity=24.4943820224719, Blast_Score=114, Evalue=5e-25,
Organism=Homo sapiens, GI4502043, Length=415, Percent_Identity=25.7831325301205, Blast_Score=107, Evalue=9e-23,
Organism=Homo sapiens, GI238814371, Length=415, Percent_Identity=25.7831325301205, Blast_Score=107, Evalue=9e-23,
Organism=Homo sapiens, GI310128087, Length=282, Percent_Identity=28.3687943262411, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI71773324, Length=412, Percent_Identity=25.4854368932039, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI301500698, Length=283, Percent_Identity=28.6219081272085, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI4557303, Length=441, Percent_Identity=23.1292517006803, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI73466520, Length=441, Percent_Identity=23.1292517006803, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI310128089, Length=327, Percent_Identity=27.5229357798165, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI310128095, Length=313, Percent_Identity=27.1565495207668, Blast_Score=88, Evalue=5e-17,
Organism=Homo sapiens, GI73695881, Length=323, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI73695879, Length=323, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI310128097, Length=260, Percent_Identity=28.4615384615385, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI310128099, Length=232, Percent_Identity=28.448275862069, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI310128101, Length=230, Percent_Identity=28.2608695652174, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI223972651, Length=494, Percent_Identity=25.3036437246964, Blast_Score=80, Evalue=1e-14,
Organism=Escherichia coli, GI1787250, Length=1041, Percent_Identity=47.1661863592699, Blast_Score=901, Evalue=0.0,
Organism=Escherichia coli, GI87081896, Length=503, Percent_Identity=32.20675944334, Blast_Score=212, Evalue=8e-56,
Organism=Escherichia coli, GI1789015, Length=473, Percent_Identity=30.4439746300211, Blast_Score=187, Evalue=4e-48,
Organism=Escherichia coli, GI1787715, Length=471, Percent_Identity=31.6348195329087, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI1787558, Length=481, Percent_Identity=29.7297297297297, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1788042, Length=461, Percent_Identity=31.0195227765727, Blast_Score=172, Evalue=8e-44,
Organism=Escherichia coli, GI1787684, Length=432, Percent_Identity=28.9351851851852, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI87082295, Length=488, Percent_Identity=28.0737704918033, Blast_Score=142, Evalue=2e-34,
Organism=Escherichia coli, GI1786504, Length=440, Percent_Identity=26.1363636363636, Blast_Score=137, Evalue=4e-33,
Organism=Escherichia coli, GI87081926, Length=431, Percent_Identity=26.6821345707657, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI1787653, Length=342, Percent_Identity=23.3918128654971, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17534447, Length=476, Percent_Identity=31.7226890756302, Blast_Score=197, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI133930964, Length=492, Percent_Identity=29.0650406504065, Blast_Score=178, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25144435, Length=446, Percent_Identity=30.4932735426009, Blast_Score=175, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17562198, Length=444, Percent_Identity=30.4054054054054, Blast_Score=173, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI115532534, Length=397, Percent_Identity=31.4861460957179, Blast_Score=172, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17551164, Length=454, Percent_Identity=30.6167400881057, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32564736, Length=408, Percent_Identity=30.3921568627451, Blast_Score=161, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI115534176, Length=462, Percent_Identity=29.2207792207792, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32564151, Length=428, Percent_Identity=29.4392523364486, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17534119, Length=481, Percent_Identity=27.4428274428274, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71995606, Length=463, Percent_Identity=28.0777537796976, Blast_Score=147, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71986308, Length=419, Percent_Identity=28.6396181384248, Blast_Score=143, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI25143874, Length=435, Percent_Identity=26.6666666666667, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25143876, Length=435, Percent_Identity=26.6666666666667, Blast_Score=139, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71995613, Length=419, Percent_Identity=27.2076372315036, Blast_Score=133, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71990744, Length=308, Percent_Identity=30.1948051948052, Blast_Score=116, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI25146391, Length=451, Percent_Identity=24.8337028824834, Blast_Score=106, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI25146394, Length=451, Percent_Identity=24.8337028824834, Blast_Score=105, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI32566756, Length=451, Percent_Identity=24.8337028824834, Blast_Score=105, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17564084, Length=463, Percent_Identity=25.2699784017279, Blast_Score=105, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320917, Length=467, Percent_Identity=30.6209850107066, Blast_Score=188, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6324950, Length=447, Percent_Identity=29.082774049217, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6321826, Length=517, Percent_Identity=29.4003868471954, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6323821, Length=469, Percent_Identity=29.637526652452, Blast_Score=178, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6323822, Length=484, Percent_Identity=28.5123966942149, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6325196, Length=491, Percent_Identity=29.938900203666, Blast_Score=174, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6319478, Length=489, Percent_Identity=27.6073619631902, Blast_Score=150, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6321828, Length=481, Percent_Identity=25.5717255717256, Blast_Score=122, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6323757, Length=415, Percent_Identity=23.1325301204819, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24668425, Length=486, Percent_Identity=30.0411522633745, Blast_Score=197, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24668417, Length=486, Percent_Identity=30.0411522633745, Blast_Score=197, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24668413, Length=486, Percent_Identity=30.0411522633745, Blast_Score=197, Evalue=3e-50,
Organism=Drosophila melanogaster, GI20129399, Length=515, Percent_Identity=30.6796116504854, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24585660, Length=470, Percent_Identity=27.2340425531915, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281362580, Length=453, Percent_Identity=28.476821192053, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI62472918, Length=453, Percent_Identity=28.476821192053, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI62472926, Length=453, Percent_Identity=28.476821192053, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI62472936, Length=453, Percent_Identity=28.476821192053, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI21356737, Length=453, Percent_Identity=28.476821192053, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24650465, Length=443, Percent_Identity=29.1196388261851, Blast_Score=173, Evalue=6e-43,
Organism=Drosophila melanogaster, GI28571798, Length=483, Percent_Identity=26.5010351966874, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI28571796, Length=483, Percent_Identity=26.5010351966874, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI28571794, Length=483, Percent_Identity=26.5010351966874, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI28571806, Length=483, Percent_Identity=26.5010351966874, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI28571802, Length=483, Percent_Identity=26.5010351966874, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI28571800, Length=483, Percent_Identity=26.5010351966874, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24666674, Length=477, Percent_Identity=28.5115303983228, Blast_Score=150, Evalue=4e-36,
Organism=Drosophila melanogaster, GI28574525, Length=475, Percent_Identity=24, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24638876, Length=425, Percent_Identity=28.2352941176471, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24638878, Length=425, Percent_Identity=28.2352941176471, Blast_Score=128, Evalue=3e-29,
Organism=Drosophila melanogaster, GI45552499, Length=464, Percent_Identity=25.2155172413793, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281360303, Length=464, Percent_Identity=25.2155172413793, Blast_Score=93, Evalue=9e-19,
Organism=Drosophila melanogaster, GI281360299, Length=464, Percent_Identity=25.2155172413793, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360297, Length=464, Percent_Identity=25.2155172413793, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360295, Length=464, Percent_Identity=25.2155172413793, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24586250, Length=464, Percent_Identity=25.2155172413793, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360301, Length=464, Percent_Identity=25.2155172413793, Blast_Score=91, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 115649; Mature: 115649

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAITMFKASEVLAGRYDSANLDELFKAVTDNYIVDEEQYLSELIKLVPSSDEAIERVTR
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECHHHHHHHHHHHCCCCHHHHHHHHH
RAHELVNKVRQFDKKGLMVGIDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIED
HHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
KLSGAKWDEHLSKSDSVLVNASTWGLMLTGKIVKLDKKIDGTPSNLLSRLVNRLGEPVIR
HCCCCCHHHHHCCCCCEEEEECCCCEEEECEEEEECCCCCCCHHHHHHHHHHHHCCHHHH
QAMMAAMKIMGKQFVLGRTMKEALKNSEDKRKLGYTHSYDMLGEAALTRKDAEKYFNDYA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NAITELGAQSYNENESPRPTISIKLSALHPRYEVANEDRVLTELYDTVIRLIKLARGLNI
HHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
GISIDAEEVDRLELSLKLFQKLFNADATKGWGLLGIVVQAYSKRALPVLVWLTRLAKEQG
EEEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
DEIPVRLVKGAYWDSELKWAQQAGEAAYPLYTRKAGTDVSYLACARYLLSDATRGAIYPQ
CCCCCEEHCCCCCCHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCH
FASHNAQTVAAISDMAGDRNHEFQRLHGMGQELYDTILSEAGAKAVRIYAPIGAHKDLLP
HHCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
YLVRRLLENGANTSFVHKLVDPKTPIESLVVHPLKTLTGYKTLANNKIVLPTDIFGSDRK
HHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
NSKGLNMNIISEAEPFFAALDKFKSTQWQAGPLVNGQTLTGEHKTVVSPFDTTQTVGQVA
CCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCEEECCCCCHHHHHHHH
FADKAAIEQAVASADAAFATWTRTPVEVRASALQKLADLLEENREELIALCTREAGKSIQ
HHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DGIDEVREAVDFCRYYAVQAKKLMSKPELLPGPTGELNELFLQGRGVFVCISPWNFPLAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHH
FLGQVSAALAAGNTVVAKPAEQTSIIGYRAVQLAHQAGIPTDVLQYLPGTGATVGNALTA
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCC
DERIGGVCFTGSTGTAKLINRTLANREGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVS
HHCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCHHHHHHHHHH
SSFTSAGQRCSALRVLFLQEDIADRVIDVLQGAMDELVIGNPSSVKTDVGPVIDATAKAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHCCHHHCC
LDAHIDHIKQVGKLIKQMSLPAGTENGHFVSPTAVEIDSIKVLEKEHFGPILHVIRYKAS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEECHHHHHHHHHCHHHHHHHHHHHH
ELAHVIDEINSTGFGLTLGIHSRNEGHALEVADKVNVGNVYINRNQIGAVVGVQPFGGQG
HHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEECCCCCEEEECCCCCCCC
LSGTGPKAGGPHYLTRFVTEKTRTNNITAIGGNATLLSLGDSDA
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCC
>Mature Secondary Structure
MEAITMFKASEVLAGRYDSANLDELFKAVTDNYIVDEEQYLSELIKLVPSSDEAIERVTR
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECHHHHHHHHHHHCCCCHHHHHHHHH
RAHELVNKVRQFDKKGLMVGIDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIED
HHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
KLSGAKWDEHLSKSDSVLVNASTWGLMLTGKIVKLDKKIDGTPSNLLSRLVNRLGEPVIR
HCCCCCHHHHHCCCCCEEEEECCCCEEEECEEEEECCCCCCCHHHHHHHHHHHHCCHHHH
QAMMAAMKIMGKQFVLGRTMKEALKNSEDKRKLGYTHSYDMLGEAALTRKDAEKYFNDYA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NAITELGAQSYNENESPRPTISIKLSALHPRYEVANEDRVLTELYDTVIRLIKLARGLNI
HHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
GISIDAEEVDRLELSLKLFQKLFNADATKGWGLLGIVVQAYSKRALPVLVWLTRLAKEQG
EEEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
DEIPVRLVKGAYWDSELKWAQQAGEAAYPLYTRKAGTDVSYLACARYLLSDATRGAIYPQ
CCCCCEEHCCCCCCHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCH
FASHNAQTVAAISDMAGDRNHEFQRLHGMGQELYDTILSEAGAKAVRIYAPIGAHKDLLP
HHCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
YLVRRLLENGANTSFVHKLVDPKTPIESLVVHPLKTLTGYKTLANNKIVLPTDIFGSDRK
HHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
NSKGLNMNIISEAEPFFAALDKFKSTQWQAGPLVNGQTLTGEHKTVVSPFDTTQTVGQVA
CCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCEEECCCCCHHHHHHHH
FADKAAIEQAVASADAAFATWTRTPVEVRASALQKLADLLEENREELIALCTREAGKSIQ
HHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DGIDEVREAVDFCRYYAVQAKKLMSKPELLPGPTGELNELFLQGRGVFVCISPWNFPLAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHH
FLGQVSAALAAGNTVVAKPAEQTSIIGYRAVQLAHQAGIPTDVLQYLPGTGATVGNALTA
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCC
DERIGGVCFTGSTGTAKLINRTLANREGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVS
HHCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCHHHHHHHHHH
SSFTSAGQRCSALRVLFLQEDIADRVIDVLQGAMDELVIGNPSSVKTDVGPVIDATAKAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHCCHHHCC
LDAHIDHIKQVGKLIKQMSLPAGTENGHFVSPTAVEIDSIKVLEKEHFGPILHVIRYKAS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEECHHHHHHHHHCHHHHHHHHHHHH
ELAHVIDEINSTGFGLTLGIHSRNEGHALEVADKVNVGNVYINRNQIGAVVGVQPFGGQG
HHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEECCCCCEEEECCCCCCCC
LSGTGPKAGGPHYLTRFVTEKTRTNNITAIGGNATLLSLGDSDA
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]