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The map label for this gene is erg3 [H]

Identifier: 117919241

GI number: 117919241

Start: 909849

End: 910712

Strand: Direct

Name: erg3 [H]

Synonym: Shewana3_0789

Alternate gene names: 117919241

Gene position: 909849-910712 (Clockwise)

Preceding gene: 117919240

Following gene: 117919242

Centisome position: 18.3

GC content: 46.06

Gene sequence:

>864_bases
ATGGATATCGCCGCGTTAATCAATCACCCCGAGGTGTTGCTGCTGGTATTGGCTCCGCTATTTTTTGTCTGCATTTTGCT
GGAATGGTATTTCGGCGACAGAAGACAAAAACTACCAGTGAGTGCCCGTTATCACACCAAGGAAGTGCTGTGTAATTTTA
GTCTTGCCGCCATGCATCAAGGGGTGGATATCCTCGCGGGTTTGCTGATTGCTAAGTTGTATCTAGCGGTATTTGGTTGG
AAATTATTCGATATTCAAATGGGGCCACTCAGCTTTGTGCTGCTGATGATTGCCCAAGATTTTTGCTATTACTGGTTCCA
TCGTGCGAGCCATAGAGTGCGTTGGATGTGGGCGGCCCATGTGGTACACCATAGCTCGGAGAATATGAATTTTAGCACTG
CGTTTCGCCAGAGTTTGATGTATCCCTTTGCTGGTATGTGGGTGTTTTGGTTGCCGCTGGTGATCTTAGGCTTCGACCCT
AATTGGGTGGTTTTTGTGGTACTGCTGAACTTAGGATTGCAGTTTTTTGTGCATACCCAAGCGGTGAAAAAACTAGGCCC
ATTAGAATGGCTGTTTAATACGCCATCACATCACAGAGTGCACCATGGGCGTAATCCACAATATATTGATAAAAATTATG
CTGGTATTTTAATCATCTGGGACAAACTATTTGGTACCTTTGTACCCGAAGAGGAAACAGTGATTTACGGGATCACTAAA
CCCGTCAACAGTTTTAATCCACTTAAAGTGACCTTTAGCGAATGGCGCGATATGTTCAGCGAGGTGACGACGCGGGGGCT
GACATTCTCGGAGCGATGTAAAATCCTCTTCGCCCCTCCTGCAAGCCAGCAAAAGGATGAATGA

Upstream 100 bases:

>100_bases
CTCAACAATGTGTTGGGATTGACCGAGGACCATTACGCTCGTTGGTAGACTATGGGCTGATTTACGCTTTAATACAATAA
TAACAATAGGATAAAGGTAT

Downstream 100 bases:

>100_bases
TTTAGCTCAATACGCGAGCAGTAGCCACTCAACGAGTGGTTCGCTCTTCATTAAATAGTGCAAATGGCTAATAGGAGTCA
GAGCTTAGCCTTGCTAGCCT

Product: sterol desaturase family protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MDIAALINHPEVLLLVLAPLFFVCILLEWYFGDRRQKLPVSARYHTKEVLCNFSLAAMHQGVDILAGLLIAKLYLAVFGW
KLFDIQMGPLSFVLLMIAQDFCYYWFHRASHRVRWMWAAHVVHHSSENMNFSTAFRQSLMYPFAGMWVFWLPLVILGFDP
NWVVFVVLLNLGLQFFVHTQAVKKLGPLEWLFNTPSHHRVHHGRNPQYIDKNYAGILIIWDKLFGTFVPEEETVIYGITK
PVNSFNPLKVTFSEWRDMFSEVTTRGLTFSERCKILFAPPASQQKDE

Sequences:

>Translated_287_residues
MDIAALINHPEVLLLVLAPLFFVCILLEWYFGDRRQKLPVSARYHTKEVLCNFSLAAMHQGVDILAGLLIAKLYLAVFGW
KLFDIQMGPLSFVLLMIAQDFCYYWFHRASHRVRWMWAAHVVHHSSENMNFSTAFRQSLMYPFAGMWVFWLPLVILGFDP
NWVVFVVLLNLGLQFFVHTQAVKKLGPLEWLFNTPSHHRVHHGRNPQYIDKNYAGILIIWDKLFGTFVPEEETVIYGITK
PVNSFNPLKVTFSEWRDMFSEVTTRGLTFSERCKILFAPPASQQKDE
>Mature_287_residues
MDIAALINHPEVLLLVLAPLFFVCILLEWYFGDRRQKLPVSARYHTKEVLCNFSLAAMHQGVDILAGLLIAKLYLAVFGW
KLFDIQMGPLSFVLLMIAQDFCYYWFHRASHRVRWMWAAHVVHHSSENMNFSTAFRQSLMYPFAGMWVFWLPLVILGFDP
NWVVFVVLLNLGLQFFVHTQAVKKLGPLEWLFNTPSHHRVHHGRNPQYIDKNYAGILIIWDKLFGTFVPEEETVIYGITK
PVNSFNPLKVTFSEWRDMFSEVTTRGLTFSERCKILFAPPASQQKDE

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=207, Percent_Identity=48.3091787439614, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI25144659, Length=191, Percent_Identity=41.3612565445026, Blast_Score=137, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 33427; Mature: 33427

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIAALINHPEVLLLVLAPLFFVCILLEWYFGDRRQKLPVSARYHTKEVLCNFSLAAMHQ
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GVDILAGLLIAKLYLAVFGWKLFDIQMGPLSFVLLMIAQDFCYYWFHRASHRVRWMWAAH
CHHHHHHHHHHHHHHHHHCCHHEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHH
VVHHSSENMNFSTAFRQSLMYPFAGMWVFWLPLVILGFDPNWVVFVVLLNLGLQFFVHTQ
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AVKKLGPLEWLFNTPSHHRVHHGRNPQYIDKNYAGILIIWDKLFGTFVPEEETVIYGITK
HHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCEEEEEECC
PVNSFNPLKVTFSEWRDMFSEVTTRGLTFSERCKILFAPPASQQKDE
CCCCCCCEEEEHHHHHHHHHHHHHCCCCHHHCCEEEECCCCCCCCCC
>Mature Secondary Structure
MDIAALINHPEVLLLVLAPLFFVCILLEWYFGDRRQKLPVSARYHTKEVLCNFSLAAMHQ
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GVDILAGLLIAKLYLAVFGWKLFDIQMGPLSFVLLMIAQDFCYYWFHRASHRVRWMWAAH
CHHHHHHHHHHHHHHHHHCCHHEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHH
VVHHSSENMNFSTAFRQSLMYPFAGMWVFWLPLVILGFDPNWVVFVVLLNLGLQFFVHTQ
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AVKKLGPLEWLFNTPSHHRVHHGRNPQYIDKNYAGILIIWDKLFGTFVPEEETVIYGITK
HHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCEEEEEECC
PVNSFNPLKVTFSEWRDMFSEVTTRGLTFSERCKILFAPPASQQKDE
CCCCCCCEEEEHHHHHHHHHHHHHCCCCHHHCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]