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The map label for this gene is murA [H]

Identifier: 117919136

GI number: 117919136

Start: 800823

End: 802082

Strand: Direct

Name: murA [H]

Synonym: Shewana3_0684

Alternate gene names: 117919136

Gene position: 800823-802082 (Clockwise)

Preceding gene: 117919135

Following gene: 117919138

Centisome position: 16.11

GC content: 52.3

Gene sequence:

>1260_bases
GTGGATAAATTAGCGATTCAAGCAAGCCCTCCGCTTGCTGGTGATGTGATTATTTCCGGCGCTAAAAATGCTGCGCTGCC
GATTCTGATGGCAGGCGTGTTAGCCGAGACTGATTTTATTGTGTCGAATGTCCCCAATTTGCGCGATGTGAGCACCAGCT
GTAAATTGCTGCGCTGCCTAGGCGCCGATGTGGATGAATTAGGCAATGGTCAAATCCGTATTTCGACCAAGAACCTTAAC
GAGTTCTGCGCACCTTACGATCTCGTTAAGACCATGCGTGCCTCGATTCTGATCCTTGGCCCGTTATTAGCCCGTTATGG
CACCGCAGATGTGTCATTACCCGGTGGCTGCGCCATTGGTGCCCGTCCAGTAAACCTTCACTTACATGGCCTCGAAATGA
TGGGCGCCAAGATTGAAGTGAAAGAAGGCTATATCAAGGCCCGTGTCGATGGTCGCTTAAAGGGCGCCCATATTTTTATG
GACATGGTGAGCGTCGGAGCGACCGAAAACCTGTTGATGGCCGCGGCACTTGCCGATGGCGAAACCGTGATTGAAAACGC
AGCCCGTGAACCAGAAGTGATCGACTTGGCTAACTGTTTGATTGCCATGGGCGCGAAGATCACCGGTGTTGGCAGTGCCA
CACTGCGTATTCAAGGCGTTGAGCGTCTACAGGGCTGTGAGTACCGCGTGATGCCAGACCGTATCGAAACCGGTTCCTTC
CTCGTGGCCGCAGCTGTGACCCGTGGTCGTATCCGTTGCTTAAAGGCCGATCCTGCTTCGTTAGAGTCTGTTATCGCGAA
ACTTGAAGATGCGGGCGCCAAGATCACCACTGGTGAAGATTGGATTGAGCTCGATATGGAAGGCAAGCGTCCGAAAGCGG
TAAATATCAAGACGGCGCCATACCCAGGTTTTCCAACCGATATGCAGGCGCAGTTCTGCGTGCTCAACGTATTAGCCCAG
GGCACGGCGACCATTACCGAAACCATCTTCGAAAACCGCTTTATGCACGTGCCAGAACTTATCCGTATGGGCGCGAACAT
GGAGCTTGAAGGCAATACCTGCATTATTCAAGGCATTGAGTCTTTGAGTGGTGCGCAGGTGATGGCGACCGATTTACGCG
CTTCGGCAAGTTTAGTGATCGCAGGTTTAGTCGCCGATGGTAAAACCATCGTCGATCGCATCTATCACTTAGATCGCGGT
TATGAGCATATCGAGCAGAAGTTCCAAGGATTGGGCGCGCATGTAGAGCGTGTGCAATAA

Upstream 100 bases:

>100_bases
CTATATCGCCAGCGGTGAGTTACATGCATTAACGATTAAAACTTTCACGCCGACTCAATGGAAACGCGAGAAAATTTTCA
ACAGCTAGTAGTGAGGAAAA

Downstream 100 bases:

>100_bases
CATTCGCGTAGGATTCGCTCCCAATAAAAAACCAGCCAAGTGCTGGTTTTTTTATTGTATTCATTCAGCTGAAAAGACAG
GGGAATAAGTAAGAGTAAGT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MDKLAIQASPPLAGDVIISGAKNAALPILMAGVLAETDFIVSNVPNLRDVSTSCKLLRCLGADVDELGNGQIRISTKNLN
EFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFM
DMVSVGATENLLMAAALADGETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCEYRVMPDRIETGSF
LVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMEGKRPKAVNIKTAPYPGFPTDMQAQFCVLNVLAQ
GTATITETIFENRFMHVPELIRMGANMELEGNTCIIQGIESLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRG
YEHIEQKFQGLGAHVERVQ

Sequences:

>Translated_419_residues
MDKLAIQASPPLAGDVIISGAKNAALPILMAGVLAETDFIVSNVPNLRDVSTSCKLLRCLGADVDELGNGQIRISTKNLN
EFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFM
DMVSVGATENLLMAAALADGETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCEYRVMPDRIETGSF
LVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMEGKRPKAVNIKTAPYPGFPTDMQAQFCVLNVLAQ
GTATITETIFENRFMHVPELIRMGANMELEGNTCIIQGIESLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRG
YEHIEQKFQGLGAHVERVQ
>Mature_419_residues
MDKLAIQASPPLAGDVIISGAKNAALPILMAGVLAETDFIVSNVPNLRDVSTSCKLLRCLGADVDELGNGQIRISTKNLN
EFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFM
DMVSVGATENLLMAAALADGETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCEYRVMPDRIETGSF
LVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMEGKRPKAVNIKTAPYPGFPTDMQAQFCVLNVLAQ
GTATITETIFENRFMHVPELIRMGANMELEGNTCIIQGIESLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRG
YEHIEQKFQGLGAHVERVQ

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=65.8711217183771, Blast_Score=572, Evalue=1e-164,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44779; Mature: 44779

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLAIQASPPLAGDVIISGAKNAALPILMAGVLAETDFIVSNVPNLRDVSTSCKLLRCL
CCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHH
GADVDELGNGQIRISTKNLNEFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIG
CCCHHHCCCCEEEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
ARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFMDMVSVGATENLLMAAALADG
CEEEEEEEECHHHCCCEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCHHHEEEEECCCC
ETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCEYRVMPDRIETGSF
HHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCEEEEEEEHHHHCCCCEEECCCCCCCCCE
LVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMEGKRPKAVNIKTAP
EEEEECCCCCEEEEECCHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCEEEEECCC
YPGFPTDMQAQFCVLNVLAQGTATITETIFENRFMHVPELIRMGANMELEGNTCIIQGIE
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCCEEECCCEEEEEEHH
SLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRGYEHIEQKFQGLGAHVERVQ
CCCCCEEEEHHHHCCCEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MDKLAIQASPPLAGDVIISGAKNAALPILMAGVLAETDFIVSNVPNLRDVSTSCKLLRCL
CCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHH
GADVDELGNGQIRISTKNLNEFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIG
CCCHHHCCCCEEEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
ARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFMDMVSVGATENLLMAAALADG
CEEEEEEEECHHHCCCEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCHHHEEEEECCCC
ETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCEYRVMPDRIETGSF
HHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCEEEEEEEHHHHCCCCEEECCCCCCCCCE
LVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMEGKRPKAVNIKTAP
EEEEECCCCCEEEEECCHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCEEEEECCC
YPGFPTDMQAQFCVLNVLAQGTATITETIFENRFMHVPELIRMGANMELEGNTCIIQGIE
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCCEEECCCEEEEEEHH
SLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRGYEHIEQKFQGLGAHVERVQ
CCCCCEEEEHHHHCCCEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA