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The map label for this gene is ytfL [H]

Identifier: 117918810

GI number: 117918810

Start: 387672

End: 388988

Strand: Direct

Name: ytfL [H]

Synonym: Shewana3_0353

Alternate gene names: 117918810

Gene position: 387672-388988 (Clockwise)

Preceding gene: 117918808

Following gene: 117918812

Centisome position: 7.8

GC content: 48.67

Gene sequence:

>1317_bases
ATGAGTCTCTTAGATAACGTGATGATTATATTGTGCTTAATTGGCGCAAGTTGTTTCTTTTCCATGTCAGAAATCGCTTT
GGCCGCATCACGCAAAATCCGTTTACGTCAATTAGCCGATGAAGGCGATAGCCGCGCCGAAAAAGTGCTGCAACTCCAAG
CCCAGCCCGGTAGCTTTTTTACTGTGGTGCAAATTGGCCTGAATGCCGTTGCCATCATGGGCGGTATTGTGGGTGAATCG
GCGTTTCGTCCCTATTTTTACCAGTTTTTAAGTGCGTGGTTGAGCGACCCTTGGCTGAGCCAGCTGAGCTTCTTCCTGTC
TTTCTTTGTGGTAACCAGTGCCTTTATTTTGGTCGCCGATTTAATGCCTAAGCGAATTGCGATGGCGATGCCTGAATCGG
TTGCGCTAGTGGTTGTTGGGCCAATGAGTTTCTGCATCGCGATCCTGCGTCCATTGGTGTGGTTTTTCAATGGCATGGCT
AGCGGTATCTTCAAGTTGCTGCAGATCCCTACCGTGCGTAACGATGAAATCACCCCAGATGATATTTATGCGGTCATGAA
CGCGGGGGCTGAAGCTGGGGTGCTCGACAAGGGCGAGCAACAAATGATCGAAAATGTGTTTGAAATGCAAACCGTTTCGG
TAACGTCCGCCATGACGGCCCGCGAAAGCTTAGTGTATTTCCTGTTGCAAGACAGCGAGGAGGATATCAAGCGTAAGATT
GCCGAAGATCCCCATACTAAGTTTTTGGTCTGCGATGGCCAATTGGATATGGTCAAAGGGTTTGTGGATGCGAAGGAACT
GCTGATCCGTGTGATCAACGGTGAAAAAATTACCTTAAAAGACAACAGTCTTGTGCATACCTCGCTGATTATTCCCGATA
CCTTAAGCCTGTCTGAGGCGATGGAATACTTCAAAAATAGCCGCGCCGATTTCGCGGTGGTGATGAACGAATATGCTCTG
GTTGTGGGGATTGTCACCACCAACGATCTGCAGCGCGCGGTGATGGGGGCCTGGTCGCTACACGAGAGCGAAGAGCAAAT
TATTGCCCGTGATGGCAATTCTTGGTTAGTGGATGGGGTGACGCCGATTACCGACGTAATGCGTGCCTTCGATATTGAGG
AATTCCCCCATAATCAAAACTACGAAACCATTGCTGGCTTTATGATGTACATGCTGCGTAAGATCCCCAAGCGCACCGAC
TTTGTTAACTATGCTGGCTACAAGTTTGAAGTGGTGGATATCGACGCCTACAAGGTCGACCAATTGCTTGTAACTCGTAT
CGATGGCAACGATAAGTTGATGTCGCCAGATACCTAA

Upstream 100 bases:

>100_bases
CACAGGCTTGTGCCGCTTTACGGGGCCAAATCCAACTGACTCGCGAAAATCACTGCGCGGGTTGGTACAAGTAAGTCTAG
TGTGAAACAAAAGGTGTTAC

Downstream 100 bases:

>100_bases
TCTTATCAACATCATAAAAAAACGGGACTCAGTCCCGTTTTTTATATTGCTACTAAAATTTAGATCGCTTCTAAAAACGC
ATTCACTATCGGATCGTCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSLLDNVMIILCLIGASCFFSMSEIALAASRKIRLRQLADEGDSRAEKVLQLQAQPGSFFTVVQIGLNAVAIMGGIVGES
AFRPYFYQFLSAWLSDPWLSQLSFFLSFFVVTSAFILVADLMPKRIAMAMPESVALVVVGPMSFCIAILRPLVWFFNGMA
SGIFKLLQIPTVRNDEITPDDIYAVMNAGAEAGVLDKGEQQMIENVFEMQTVSVTSAMTARESLVYFLLQDSEEDIKRKI
AEDPHTKFLVCDGQLDMVKGFVDAKELLIRVINGEKITLKDNSLVHTSLIIPDTLSLSEAMEYFKNSRADFAVVMNEYAL
VVGIVTTNDLQRAVMGAWSLHESEEQIIARDGNSWLVDGVTPITDVMRAFDIEEFPHNQNYETIAGFMMYMLRKIPKRTD
FVNYAGYKFEVVDIDAYKVDQLLVTRIDGNDKLMSPDT

Sequences:

>Translated_438_residues
MSLLDNVMIILCLIGASCFFSMSEIALAASRKIRLRQLADEGDSRAEKVLQLQAQPGSFFTVVQIGLNAVAIMGGIVGES
AFRPYFYQFLSAWLSDPWLSQLSFFLSFFVVTSAFILVADLMPKRIAMAMPESVALVVVGPMSFCIAILRPLVWFFNGMA
SGIFKLLQIPTVRNDEITPDDIYAVMNAGAEAGVLDKGEQQMIENVFEMQTVSVTSAMTARESLVYFLLQDSEEDIKRKI
AEDPHTKFLVCDGQLDMVKGFVDAKELLIRVINGEKITLKDNSLVHTSLIIPDTLSLSEAMEYFKNSRADFAVVMNEYAL
VVGIVTTNDLQRAVMGAWSLHESEEQIIARDGNSWLVDGVTPITDVMRAFDIEEFPHNQNYETIAGFMMYMLRKIPKRTD
FVNYAGYKFEVVDIDAYKVDQLLVTRIDGNDKLMSPDT
>Mature_437_residues
SLLDNVMIILCLIGASCFFSMSEIALAASRKIRLRQLADEGDSRAEKVLQLQAQPGSFFTVVQIGLNAVAIMGGIVGESA
FRPYFYQFLSAWLSDPWLSQLSFFLSFFVVTSAFILVADLMPKRIAMAMPESVALVVVGPMSFCIAILRPLVWFFNGMAS
GIFKLLQIPTVRNDEITPDDIYAVMNAGAEAGVLDKGEQQMIENVFEMQTVSVTSAMTARESLVYFLLQDSEEDIKRKIA
EDPHTKFLVCDGQLDMVKGFVDAKELLIRVINGEKITLKDNSLVHTSLIIPDTLSLSEAMEYFKNSRADFAVVMNEYALV
VGIVTTNDLQRAVMGAWSLHESEEQIIARDGNSWLVDGVTPITDVMRAFDIEEFPHNQNYETIAGFMMYMLRKIPKRTDF
VNYAGYKFEVVDIDAYKVDQLLVTRIDGNDKLMSPDT

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=387, Percent_Identity=26.0981912144703, Blast_Score=155, Evalue=7e-38,
Organism=Escherichia coli, GI1790664, Length=434, Percent_Identity=58.7557603686636, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI145693175, Length=419, Percent_Identity=23.3890214797136, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI87082033, Length=264, Percent_Identity=31.0606060606061, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1788119, Length=234, Percent_Identity=26.9230769230769, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1786879, Length=268, Percent_Identity=22.0149253731343, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48995; Mature: 48864

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLDNVMIILCLIGASCFFSMSEIALAASRKIRLRQLADEGDSRAEKVLQLQAQPGSFF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEE
TVVQIGLNAVAIMGGIVGESAFRPYFYQFLSAWLSDPWLSQLSFFLSFFVVTSAFILVAD
EHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LMPKRIAMAMPESVALVVVGPMSFCIAILRPLVWFFNGMASGIFKLLQIPTVRNDEITPD
HHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
DIYAVMNAGAEAGVLDKGEQQMIENVFEMQTVSVTSAMTARESLVYFLLQDSEEDIKRKI
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHH
AEDPHTKFLVCDGQLDMVKGFVDAKELLIRVINGEKITLKDNSLVHTSLIIPDTLSLSEA
HCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCCHHHH
MEYFKNSRADFAVVMNEYALVVGIVTTNDLQRAVMGAWSLHESEEQIIARDGNSWLVDGV
HHHHHCCCCCEEHHEECCEEEEEEEECHHHHHHHHHHHHCCCCCHHHEEECCCCEEECCC
TPITDVMRAFDIEEFPHNQNYETIAGFMMYMLRKIPKRTDFVNYAGYKFEVVDIDAYKVD
CHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCEEEEEEECCHHHHC
QLLVTRIDGNDKLMSPDT
EEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SLLDNVMIILCLIGASCFFSMSEIALAASRKIRLRQLADEGDSRAEKVLQLQAQPGSFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEE
TVVQIGLNAVAIMGGIVGESAFRPYFYQFLSAWLSDPWLSQLSFFLSFFVVTSAFILVAD
EHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LMPKRIAMAMPESVALVVVGPMSFCIAILRPLVWFFNGMASGIFKLLQIPTVRNDEITPD
HHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
DIYAVMNAGAEAGVLDKGEQQMIENVFEMQTVSVTSAMTARESLVYFLLQDSEEDIKRKI
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHH
AEDPHTKFLVCDGQLDMVKGFVDAKELLIRVINGEKITLKDNSLVHTSLIIPDTLSLSEA
HCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCCHHHH
MEYFKNSRADFAVVMNEYALVVGIVTTNDLQRAVMGAWSLHESEEQIIARDGNSWLVDGV
HHHHHCCCCCEEHHEECCEEEEEEEECHHHHHHHHHHHHCCCCCHHHEEECCCCEEECCC
TPITDVMRAFDIEEFPHNQNYETIAGFMMYMLRKIPKRTDFVNYAGYKFEVVDIDAYKVD
CHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCEEEEEEECCHHHHC
QLLVTRIDGNDKLMSPDT
EEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]