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The map label for this gene is silC [H]

Identifier: 117676236

GI number: 117676236

Start: 180422

End: 181807

Strand: Direct

Name: silC [H]

Synonym: Shewana3_4297

Alternate gene names: 117676236

Gene position: 180422-181807 (Clockwise)

Preceding gene: 117676233

Following gene: 117676237

Centisome position: 64.68

GC content: 51.8

Gene sequence:

>1386_bases
ATGTTCAAATTAAAATTACTCAGCATTAGCACGATATTCATCCTGACCGGTTGTGTCTCTCTGGCACCTGAATATCAGCG
CCCGGCAGCACCGGTACCCCAGCAGTTTTCACTGTCCCGAAACAGCCTGATGCCAGCAGTGAATGGTTATCAGGATACGG
GCTGGCGTAACTTTTTTGTCGATCCCCAGGTTACCCGGCTGATCGGGGAAGCCCTTGCTAATAACCGTAATTTGAGAATG
GCTGCCCTGAAGGTTGAAGAGGCCCGGGCCCAGTTCAACGTCACGGATGCAGATCGTTATCCCCAGCTGAATGCCTCATC
CGGGATCACCTACAGCGGTGGTCTGAAAGGCGACAAGCCGACCACACAGGAGTACGACGCGGGTCTGGAACTCCGCTATG
AGCTCGATTTTTTCGGCAAGCTCAAGAACTTGAGTGACGCTGATCGCCAGAACTACTTTGCCAGCGAAGAAGCCCGTCGG
GCTGTACATATCCTGCTGGTCTCCAGCGTTTCACAAAGCTATTTCAGCCAGCAACTGGCGTATGAACAACTCCGTATCGC
GCGGGAAACGCTGAAAAATTACGAACAGTCCTATGCTTTCGTTGAGCAACAGCTCGTGACCGGGAGTACGAATGTGCTGG
CGCTTGAACAGGCCAGGGGACAAATCGAAAGTACCCGCGCTGAGATAGCCAAACGAGAAGGCGATCTGGCTCAGGCAAAC
AATGCCCTGCAACTGGTGCTGGGAACGTACCGTGCACTGCCGCCAGAAAAAGGGATGAAAGGCGGTGAGACCGCGCCAGT
TAAACTGCCATCAAACCTGTCGTCACAAATTTTGCTGCAGCGACCGGATATTATGGAGGCGGAATACCAGCTGAAAGCTG
CTGATGCGAATATTGGCGCAGCGCGGGCGGCCTTTTTCCCGTCCATTACCCTGACCAGTGGCCTTTCCGCAAGCAGTACG
GAGCTGTCCAGTCTCTTCACGCCAGGAAGCGGAATGTGGAATTTTATCCCTAAAATTGACATTCCTGTTTTTAATGCCGG
CAGGAACAAAGCCAATCTCAAACTGGCAGAAATTCGCCAGCAACAGTCGGTGGTTAATTACGAACAAAAAATTCAGTCCG
CCTTTAAGGATGTTTCCGACACGTTTGCGCTGCGCGACAGCCTTAGCCAGCAACTTGAGTCACAGCAGCGTTATCTTGAT
TCACTTCAGATAACTCTCCAGCGAGCCAGAGGATTGTATGCAAGTGGTGCTGTCAGTTACATCGAAGTGCTGGATGCAGA
ACGTTCCCTCTTCGCTACGCAGCAAACCATTCTCGATCTTACCTATTCCCGACAGGTTAACGAAATTAATCTGTTTACTG
CGCTGGGTGGCGGTTGGGTAGAATAA

Upstream 100 bases:

>100_bases
CCTGTCACCCGACAAACAGAGAGCGTTCGGTAAAGTACCCCTATCAATACTCTGGACTTCATTTGAACCATTTACCAGGT
CTGCCTGGACGAGAAGCGTT

Downstream 100 bases:

>100_bases
ATTTATTTAATTAATCAGGAAATTAAAAATGCGTAATTCACTTAAAGCTGTTTTATTTGGTGCCTTCTCTGTCATGTTTT
CTGCCGGTCTTCATGCTGAA

Product: copper/silver efflux system outer membrane protein CusC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MFKLKLLSISTIFILTGCVSLAPEYQRPAAPVPQQFSLSRNSLMPAVNGYQDTGWRNFFVDPQVTRLIGEALANNRNLRM
AALKVEEARAQFNVTDADRYPQLNASSGITYSGGLKGDKPTTQEYDAGLELRYELDFFGKLKNLSDADRQNYFASEEARR
AVHILLVSSVSQSYFSQQLAYEQLRIARETLKNYEQSYAFVEQQLVTGSTNVLALEQARGQIESTRAEIAKREGDLAQAN
NALQLVLGTYRALPPEKGMKGGETAPVKLPSNLSSQILLQRPDIMEAEYQLKAADANIGAARAAFFPSITLTSGLSASST
ELSSLFTPGSGMWNFIPKIDIPVFNAGRNKANLKLAEIRQQQSVVNYEQKIQSAFKDVSDTFALRDSLSQQLESQQRYLD
SLQITLQRARGLYASGAVSYIEVLDAERSLFATQQTILDLTYSRQVNEINLFTALGGGWVE

Sequences:

>Translated_461_residues
MFKLKLLSISTIFILTGCVSLAPEYQRPAAPVPQQFSLSRNSLMPAVNGYQDTGWRNFFVDPQVTRLIGEALANNRNLRM
AALKVEEARAQFNVTDADRYPQLNASSGITYSGGLKGDKPTTQEYDAGLELRYELDFFGKLKNLSDADRQNYFASEEARR
AVHILLVSSVSQSYFSQQLAYEQLRIARETLKNYEQSYAFVEQQLVTGSTNVLALEQARGQIESTRAEIAKREGDLAQAN
NALQLVLGTYRALPPEKGMKGGETAPVKLPSNLSSQILLQRPDIMEAEYQLKAADANIGAARAAFFPSITLTSGLSASST
ELSSLFTPGSGMWNFIPKIDIPVFNAGRNKANLKLAEIRQQQSVVNYEQKIQSAFKDVSDTFALRDSLSQQLESQQRYLD
SLQITLQRARGLYASGAVSYIEVLDAERSLFATQQTILDLTYSRQVNEINLFTALGGGWVE
>Mature_461_residues
MFKLKLLSISTIFILTGCVSLAPEYQRPAAPVPQQFSLSRNSLMPAVNGYQDTGWRNFFVDPQVTRLIGEALANNRNLRM
AALKVEEARAQFNVTDADRYPQLNASSGITYSGGLKGDKPTTQEYDAGLELRYELDFFGKLKNLSDADRQNYFASEEARR
AVHILLVSSVSQSYFSQQLAYEQLRIARETLKNYEQSYAFVEQQLVTGSTNVLALEQARGQIESTRAEIAKREGDLAQAN
NALQLVLGTYRALPPEKGMKGGETAPVKLPSNLSSQILLQRPDIMEAEYQLKAADANIGAARAAFFPSITLTSGLSASST
ELSSLFTPGSGMWNFIPKIDIPVFNAGRNKANLKLAEIRQQQSVVNYEQKIQSAFKDVSDTFALRDSLSQQLESQQRYLD
SLQITLQRARGLYASGAVSYIEVLDAERSLFATQQTILDLTYSRQVNEINLFTALGGGWVE

Specific function: Component of the sil cation-efflux system that confers resistance to silver. May be part of a three-component cation/proton antiporter [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=458, Percent_Identity=70.5240174672489, Blast_Score=662, Evalue=0.0,
Organism=Escherichia coli, GI2367348, Length=477, Percent_Identity=25.1572327044025, Blast_Score=141, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 51126; Mature: 51126

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKLKLLSISTIFILTGCVSLAPEYQRPAAPVPQQFSLSRNSLMPAVNGYQDTGWRNFFV
CEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCEEEC
DPQVTRLIGEALANNRNLRMAALKVEEARAQFNVTDADRYPQLNASSGITYSGGLKGDKP
CHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCC
TTQEYDAGLELRYELDFFGKLKNLSDADRQNYFASEEARRAVHILLVSSVSQSYFSQQLA
CCHHHCCCCEEEEEEHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YEQLRIARETLKNYEQSYAFVEQQLVTGSTNVLALEQARGQIESTRAEIAKREGDLAQAN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCHHHHHHHHHHHHCCCHHHCC
NALQLVLGTYRALPPEKGMKGGETAPVKLPSNLSSQILLQRPDIMEAEYQLKAADANIGA
CHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCHHEECCCCCCCCCEEEEECCCCCCH
ARAAFFPSITLTSGLSASSTELSSLFTPGSGMWNFIPKIDIPVFNAGRNKANLKLAEIRQ
HHHHHCCCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHH
QQSVVNYEQKIQSAFKDVSDTFALRDSLSQQLESQQRYLDSLQITLQRARGLYASGAVSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHH
IEVLDAERSLFATQQTILDLTYSRQVNEINLFTALGGGWVE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MFKLKLLSISTIFILTGCVSLAPEYQRPAAPVPQQFSLSRNSLMPAVNGYQDTGWRNFFV
CEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCEEEC
DPQVTRLIGEALANNRNLRMAALKVEEARAQFNVTDADRYPQLNASSGITYSGGLKGDKP
CHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCC
TTQEYDAGLELRYELDFFGKLKNLSDADRQNYFASEEARRAVHILLVSSVSQSYFSQQLA
CCHHHCCCCEEEEEEHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YEQLRIARETLKNYEQSYAFVEQQLVTGSTNVLALEQARGQIESTRAEIAKREGDLAQAN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCHHHHHHHHHHHHCCCHHHCC
NALQLVLGTYRALPPEKGMKGGETAPVKLPSNLSSQILLQRPDIMEAEYQLKAADANIGA
CHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCHHEECCCCCCCCCEEEEECCCCCCH
ARAAFFPSITLTSGLSASSTELSSLFTPGSGMWNFIPKIDIPVFNAGRNKANLKLAEIRQ
HHHHHCCCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHH
QQSVVNYEQKIQSAFKDVSDTFALRDSLSQQLESQQRYLDSLQITLQRARGLYASGAVSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHH
IEVLDAERSLFATQQTILDLTYSRQVNEINLFTALGGGWVE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]